ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Oily fish | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | rs189644740 | -13.7977152592365 | 6.80157548032039 | 0.0424984604781657 |
| Oily fish | Heel bone mineral density (ebi-a-GCST90029004) | rs112516926 | -0.253891647798263 | 0.112919940889574 | 0.024549311439338 |
| Oily fish | Heel bone mineral density (ebi-a-GCST90029004) | rs114296824 | -0.243953799928036 | 0.115684603118332 | 0.0349632602827748 |
| Oily fish | Heel bone mineral density (ebi-a-GCST90029004) | rs188626385 | -0.634188491630341 | 0.0955396088759938 | 3.18045346525869e-11 |
| Oily fish | Heel bone mineral density (ebi-a-GCST90029004) | All - Inverse variance weighted | -0.111378629196068 | 0.055216375955336 | 0.0436819094236819 |
| Oily fish | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | rs139966282 | 1.82212358424752 | 0.928848247935289 | 0.0497971739899439 |
| Oily fish | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | rs9933496 | 1.52221425906073 | 0.692992483696908 | 0.0280503703581198 |
| Oily fish | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | All - Inverse variance weighted | 0.499374093199482 | 0.2067526099238 | 0.0157213116657667 |
| Oily fish | Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) | All - Inverse variance weighted | 0.683159126674625 | 0.309143150613054 | 0.0271157684898822 |
| Oily fish | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs139608354 | 11.7369180974654 | 5.77230564994269 | 0.0420206660906778 |
| Oily fish | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs188626385 | 52.4813205540806 | 24.2237730720206 | 0.0302713732909849 |
| Oily fish | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs75606319 | 14.6868045458592 | 6.60158452271446 | 0.026098744209688 |
| Oily fish | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | All - MR Egger | 10.7427036164988 | 4.0283698740481 | 0.0193834552510025 |
| Oily fish | Ankylosing hyperostosis [Forestier] (finn-b-M13_FORESTIER) | rs114296824 | -16.5064747284438 | 7.09677505015541 | 0.0200232421428099 |
| Oily fish | Ankylosing hyperostosis [Forestier] (finn-b-M13_FORESTIER) | rs188626385 | 48.4883909268245 | 22.949134161027 | 0.0346124415320698 |
| Oily fish | Ankylosing hyperostosis [Forestier] (finn-b-M13_FORESTIER) | rs61915889 | -11.0539077752534 | 5.39842007628655 | 0.0405973414877944 |
| Oily fish | Ankylosing hyperostosis [Forestier] (finn-b-M13_FORESTIER) | All - Inverse variance weighted | -4.38333748486084 | 2.21034151851868 | 0.0473557948009104 |
| Oily fish | Lower back pain or/and sciatica (finn-b-M13_LOWBACKPAINORANDSCIATICA) | rs72908311 | -1.80425101131943 | 0.881715426346147 | 0.0407272278857206 |
| Oily fish | Lower back pain or/and sciatica (finn-b-M13_LOWBACKPAINORANDSCIATICA) | rs77074496 | -2.94010063962512 | 1.48586794262157 | 0.0478487511217603 |
| Oily fish | Lower back pain or/and sciatica (finn-b-M13_LOWBACKPAINORANDSCIATICA) | All - Inverse variance weighted | -0.466816147612673 | 0.202536491508395 | 0.0211749991734582 |
| Oily fish | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | All - MR Egger | 3.013086793962 | 1.39033679936185 | 0.0493824603206638 |
| Oily fish | Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) | rs112516926 | 1.29700452207445 | 0.605691598328164 | 0.0322449167629025 |
| Oily fish | Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) | All - Inverse variance weighted | 0.558033089506181 | 0.210709216923866 | 0.0080884219486593 |
| Oily fish | Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) | All - MR Egger | 0.985633559951711 | 0.427473488503397 | 0.0382507001388564 |
| Oily fish | Pain (limb, back, neck, head abdominally) (finn-b-PAIN) | All - Inverse variance weighted | -0.245380167754119 | 0.125006939608277 | 0.049654033343787 |
| Oily fish | Fracture of lumbar spine and pelvis (finn-b-ST19_FRACT_LUMBAR_SPINE_PELVIS) | All - MR Egger | 2.33695201305813 | 1.00015234111318 | 0.0361167385165384 |
| Oily fish | Injuries to the ankle and foot (finn-b-ST19_INJURI_ANKLE_FOOT) | rs75606319 | -2.18628527343402 | 0.891368208658497 | 0.01417768313513 |
| Oily fish | Injury of muscle and tendon at hip and thigh level (finn-b-ST19_INJURY_MUSCLE_TENDON_HIP_THIGH_LEVEL) | All - MR Egger | -4.79331640627359 | 1.62905906313637 | 0.0114380190433109 |
| Oily fish | Osteocalcin (prot-a-246) | rs140451057 | 3.3279452315299 | 1.29147262360156 | 0.0099702080571946 |
| Oily fish | Osteocalcin (prot-a-246) | All - MR Egger | 1.5694229454194 | 0.661072767591712 | 0.0336799491030514 |
| Oily fish | Bone morphogenetic protein 6 (prot-a-255) | rs77074496 | -3.266339110061 | 1.16556108073908 | 0.0050727887063108 |
| Oily fish | Bone morphogenetic protein 6 (prot-a-255) | All - Inverse variance weighted | -1.18350412564605 | 0.366067433587104 | 0.0012248805989527 |
| Oily fish | Bone morphogenetic protein 6 (prot-a-255) | All - MR Egger | -1.66268542784433 | 0.660958374621221 | 0.0258191769662001 |
| Oily fish | Bone morphogenetic protein 6 (prot-a-256) | rs11678296 | 3.14016879111958 | 1.52216440503104 | 0.039116147192767 |
| Oily fish | Bone morphogenetic protein 6 (prot-a-256) | rs178461 | -3.53552888386009 | 1.36247885391322 | 0.0094611876186114 |
| Oily fish | Bone morphogenetic protein 6 (prot-a-256) | All - Inverse variance weighted | -0.824767458310677 | 0.409085751832932 | 0.0437870478038807 |
| Oily fish | Bone morphogenetic protein 6 (prot-a-256) | All - MR Egger | -1.97112224144081 | 0.664478066415344 | 0.0109216807309991 |
| Oily fish | Bone morphogenetic protein receptor type-1A (prot-a-259) | rs77074496 | -2.82937727996204 | 1.16556108073908 | 0.01520408672381 |
| Oily fish | Bone morphogenetic protein receptor type-1A (prot-a-259) | All - MR Egger | -1.81735195569023 | 0.661337734727969 | 0.0166013610010602 |
| Oily fish | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | rs17099248 | -0.507773926462534 | 0.257344351559783 | 0.0484807238693942 |
| Oily fish | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | All - Inverse variance weighted | -0.137726437703662 | 0.0637387888578254 | 0.0307112009954544 |
| Oily fish | Heel bone mineral density (BMD) T-score automated (ukb-a-500) | rs188626385 | -0.752286251505271 | 0.160100280983937 | 2.61638147588448e-06 |
| Oily fish | Heel bone mineral density (BMD) T-score automated (ukb-a-500) | All - Inverse variance weighted | -0.130429779100612 | 0.0630492950902965 | 0.0385746905069294 |
| Oily fish | Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) | rs11678296 | 0.0165152582887489 | 0.0082636614255351 | 0.045658142836895 |
| Oily fish | Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) | All - Inverse variance weighted | 0.012624092159498 | 0.0057048901541901 | 0.0269076747188148 |
| Oily fish | Internal derangement of knee (ukb-e-835_CSA) | rs9933496 | 13.81838858517 | 4.4416672096095 | 0.0018640349917813 |
| Oily fish | Internal derangement of knee (ukb-e-835_CSA) | All - Inverse variance weighted | 3.38959405815688 | 1.39696774460642 | 0.0152497072987826 |
| Oily fish | M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_CSA) | All - Inverse variance weighted | 2.43073300392125 | 1.18584272686478 | 0.0403845622757333 |
| Oily fish | M75 Shoulder lesions (ukb-e-M75_CSA) | rs11678296 | -12.8030939400944 | 5.29769589410246 | 0.0156606828829982 |
| Oily fish | M75 Shoulder lesions (ukb-e-M75_CSA) | All - MR Egger | 6.88738631870477 | 2.90714526163187 | 0.0496702014199731 |