ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
Intake (exposure) | Outcome | SNP | b | se | P-value |
---|---|---|---|---|---|
Muesli | Neck circumference (ebi-a-GCST90017135) | rs56025738 | -5.7502984753293 | 2.52480770359932 | 0.0227552286844147 |
Muesli | Neck circumference (ebi-a-GCST90017135) | All - Inverse variance weighted | -1.69366334569753 | 0.750756533515077 | 0.0240742512219052 |
Muesli | Neck circumference (BMI adjusted) (ebi-a-GCST90017136) | rs72751802 | -3.55767318228668 | 1.5369871435546 | 0.0206290336339445 |
Muesli | Neck circumference (BMI adjusted) (ebi-a-GCST90017136) | All - MR Egger | -4.9494573192856 | 1.74101499651051 | 0.0217163014555673 |
Muesli | Neck circumference (BMI adjusted) (ebi-a-GCST90017138) | rs56025738 | -4.36850449180905 | 1.96112970465622 | 0.025910877809208 |
Muesli | Neck circumference (BMI adjusted) (ebi-a-GCST90017138) | All - Inverse variance weighted | -1.22470043801167 | 0.579977284460237 | 0.0347177525928183 |
Muesli | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs72751802 | 14.3256242880133 | 5.51055096468546 | 0.0093312940227284 |
Muesli | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | All - MR Egger | 16.8366811065272 | 6.83433787526946 | 0.0391021751610558 |
Muesli | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs72751802 | 14.2058297018245 | 5.50150986384102 | 0.0098181416653726 |
Muesli | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | All - MR Egger | 16.8789261490793 | 6.83286917051993 | 0.0386950908687997 |
Muesli | Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder (finn-b-CD2_BENIGN_CONNSOFT_UPPERLIMB) | All - Inverse variance weighted | -2.04273835675133 | 1.02644815597083 | 0.0465795043343822 |
Muesli | Other bursitis of hip (finn-b-M13_BURSITISHIPOTH) | All - Inverse variance weighted | -3.8062124192161 | 1.58999775450933 | 0.0166726716249733 |
Muesli | Other specific joint derangements/joint disorders (finn-b-M13_JOINTOTH) | rs10020462 | -1.59186922182085 | 0.740274847909698 | 0.0315254899239897 |
Muesli | Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) | rs10020462 | -6.48436238958494 | 2.99449524943923 | 0.0303549612508394 |
Muesli | Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) | rs12662137 | -5.94162177640174 | 2.70952270164826 | 0.028316993308871 |
Muesli | Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) | rs2239578 | -5.25463984698489 | 2.67461168211531 | 0.0494563193865917 |
Muesli | Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) | All - Inverse variance weighted | -2.73874814132506 | 0.882898818358736 | 0.0019222089520517 |
Muesli | Otherdisorders of bone (finn-b-M13_OTHERBONE) | rs56025738 | -3.09631456363885 | 1.22130233104339 | 0.011236504547866 |
Muesli | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | All - Inverse variance weighted | -1.49977594066854 | 0.663177607141995 | 0.0237283330161797 |
Muesli | Shoulder lesions (finn-b-M13_SHOULDER) | rs12662137 | -1.38876460797824 | 0.644272240814646 | 0.0311183861605023 |
Muesli | Shoulder lesions (finn-b-M13_SHOULDER) | rs72751802 | -1.74267218776558 | 0.646438710377376 | 0.0070218929642714 |
Muesli | Shoulder lesions (finn-b-M13_SHOULDER) | All - Inverse variance weighted | -0.521814942267669 | 0.257718667405894 | 0.0428934121584603 |
Muesli | Shoulder lesions (finn-b-M13_SHOULDER) | All - MR Egger | -2.29933582724178 | 0.819748254499413 | 0.0230222570245997 |
Muesli | Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) | rs56025738 | 8.23987630399468 | 2.51697884250289 | 0.001061428747684 |
Muesli | Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) | All - Inverse variance weighted | 2.66478137667431 | 0.987528853371411 | 0.0069666562719227 |
Muesli | Injuries to the neck (finn-b-ST19_INJURI_NECK) | All - Inverse variance weighted | 0.872162919780257 | 0.437700702528241 | 0.0463051400291903 |
Muesli | Injury of muscle and tendon at hip and thigh level (finn-b-ST19_INJURY_MUSCLE_TENDON_HIP_THIGH_LEVEL) | rs78220500 | -7.47255197012763 | 3.00730089728585 | 0.0129622941367386 |
Muesli | Injury of muscle and tendon at hip and thigh level (finn-b-ST19_INJURY_MUSCLE_TENDON_HIP_THIGH_LEVEL) | All - MR Egger | -8.7443204893296 | 2.96931580922832 | 0.0185701108326628 |
Muesli | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | All - Inverse variance weighted | 6.90896636971812 | 2.69945317960575 | 0.0104854592952061 |
Muesli | Osteomodulin (prot-a-2147) | rs72751802 | 2.92479612317596 | 1.43075420863244 | 0.0409304548580216 |
Muesli | Non-cancer illness code self-reported: bone disorder (ukb-a-84) | All - Inverse variance weighted | 0.004149603002167 | 0.0020693214489694 | 0.0449313617148221 |
Muesli | Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified (ukb-b-11045) | rs218011 | -0.0150747266739645 | 0.0059130944583633 | 0.0107914541809476 |
Muesli | Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified (ukb-b-11045) | All - Inverse variance weighted | -0.0081875624767008 | 0.0026539126742504 | 0.002034897872666 |
Muesli | Non-cancer illness code, self-reported: bone disorder (ukb-b-14356) | rs2239578 | 0.0122438363074595 | 0.00518715450743 | 0.0182545105964462 |
Muesli | Non-cancer illness code, self-reported: bone disorder (ukb-b-14356) | All - Inverse variance weighted | 0.0053416449666805 | 0.0025042245192807 | 0.032920334712597 |
Muesli | Operation code: reduction or fixation of bone fracture (ukb-b-847) | rs490737 | 0.0640652218175237 | 0.0246848630183472 | 0.0094501739352462 |
Muesli | Operation code: reduction or fixation of bone fracture (ukb-b-847) | All - Inverse variance weighted | 0.0193262415782965 | 0.0077528134637878 | 0.0126738916125045 |
Muesli | Fractured bone site(s): Spine (ukb-b-873) | rs2239578 | 0.0169952392962986 | 0.0051850211236521 | 0.0010463542951939 |
Muesli | Fractured bone site(s): Spine (ukb-b-873) | All - Inverse variance weighted | 0.0073650550748057 | 0.0030479100444744 | 0.0156736270731702 |
Muesli | Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) | All - MR Egger | -0.0831363661426298 | 0.0296543888227117 | 0.0310201783079899 |
Muesli | Diagnoses - main ICD10: S42 Fracture of shoulder and upper arm (ukb-d-S42) | rs1835512 | 0.0232196739210791 | 0.0099559844637668 | 0.0196884454361034 |
Muesli | Diagnoses - main ICD10: S42 Fracture of shoulder and upper arm (ukb-d-S42) | All - Inverse variance weighted | 0.0083521032523606 | 0.0029894962234679 | 0.0052090061169886 |
Muesli | Osteoarthrosis (ukb-e-740_CSA) | All - Inverse variance weighted | 2.86377859167008 | 1.27836769070262 | 0.0250789929082015 |