ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Omelette | Total body bone mineral density (age 30-45) (ebi-a-GCST005346) | rs12508999 | 2.54849325237402 | 1.18668301187467 | 0.0317473668279387 |
| Omelette | Total body bone mineral density (age 30-45) (ebi-a-GCST005346) | All - Inverse variance weighted | 0.626985590374221 | 0.296268555490787 | 0.0343214678499475 |
| Omelette | Rheumatoid arthritis (ebi-a-GCST90018690) | rs2291762 | -0.987959044792265 | 0.478373052377712 | 0.0388995300556174 |
| Omelette | Rheumatoid arthritis (ebi-a-GCST90018690) | All - MR Egger | -3.01356718317407 | 1.07171490999835 | 0.0306789076187046 |
| Omelette | Compression fracture (ebi-a-GCST90018828) | rs73401048 | 3.72591219536469 | 1.8940572011495 | 0.0491648511235429 |
| Omelette | Compression fracture (ebi-a-GCST90018828) | All - MR Egger | -2.44428124199415 | 1.09944945905151 | 0.0445566623259998 |
| Omelette | Joint disorder (ebi-a-GCST90038654) | All - Inverse variance weighted | -0.0277518466897756 | 0.0141037779541549 | 0.0491038489846616 |
| Omelette | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | rs146053608 | 12.0343583642459 | 4.92474140323234 | 0.0145394092629217 |
| Omelette | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | rs2074128 | 17.1618741027537 | 6.21158543027425 | 0.0057293573388979 |
| Omelette | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | rs72940321 | 15.5696547429061 | 7.81985909462458 | 0.0464764548533175 |
| Omelette | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | rs75079782 | 31.5335591019997 | 12.5261040995752 | 0.0118215291433782 |
| Omelette | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | All - Inverse variance weighted | 4.13170403074871 | 1.62399096515507 | 0.0109538737186934 |
| Omelette | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs72940321 | 38.5932816939784 | 11.4942976139504 | 0.000786216048919 |
| Omelette | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs77529174 | 7.81791270391132 | 3.23843715227478 | 0.0157741113422386 |
| Omelette | Chondromalacia (finn-b-M13_CHONDROMALACIA) | All - Inverse variance weighted | 2.75989053532427 | 1.12494868081498 | 0.0141533362138705 |
| Omelette | Other intervertebral disc disorders (finn-b-M13_INTERVERTEB) | rs2447563 | -1.69312616112143 | 0.662894781286945 | 0.0106450406406109 |
| Omelette | Other intervertebral disc disorders (finn-b-M13_INTERVERTEB) | rs77529174 | 0.724318196132771 | 0.351661732905041 | 0.0394270866538407 |
| Omelette | Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) | rs72940321 | 4.40231987855669 | 1.98902339340625 | 0.0268764707664075 |
| Omelette | Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) | All - Inverse variance weighted | 0.619712715685978 | 0.314426406348149 | 0.0487317817350073 |
| Omelette | Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) | rs72940321 | 3.94301506364096 | 1.93452960180608 | 0.0415269989615106 |
| Omelette | Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) | All - Inverse variance weighted | 0.599645846110518 | 0.304706857790001 | 0.049074551821392 |
| Omelette | Postmenopausal osteoporosis with pathological fracture (finn-b-OSTPOPATFRCTURE_POSTEMENO) | rs146053608 | 10.707485032805 | 3.77489083596209 | 0.00456107068166 |
| Omelette | Other/unspecified rheumatoid arthritis (finn-b-RHEUMA_NOS) | rs72940321 | 6.68716671207816 | 3.38639990658207 | 0.0483007672689638 |
| Omelette | Other/unspecified rheumatoid arthritis (finn-b-RHEUMA_NOS) | All - Inverse variance weighted | 1.45188319207244 | 0.529610457714191 | 0.006117478618297 |
| Omelette | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | rs112108866 | 3.34177364268049 | 1.49317765028518 | 0.0252192182294581 |
| Omelette | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | All - Inverse variance weighted | 0.787556609219517 | 0.328486953360999 | 0.0165061274856498 |
| Omelette | Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) | All - MR Egger | -1.49795289154731 | 0.687697873969546 | 0.0483933624081668 |
| Omelette | Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) | rs145566815 | -0.114361672733389 | 0.0505964608786535 | 0.0238044863200333 |
| Omelette | Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) | All - MR Egger | -0.0806549118956988 | 0.0343884524464158 | 0.0355289002001947 |
| Omelette | Operation code: knee replacement/revision (ukb-b-11120) | rs17133684 | 0.0381688272222593 | 0.0170739480725472 | 0.0253844789983399 |
| Omelette | Operation code: knee replacement/revision (ukb-b-11120) | rs35193122 | -0.0418693582267496 | 0.0182374552916082 | 0.0216879205282116 |
| Omelette | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | rs145566815 | -0.0854768683701541 | 0.0432058721062938 | 0.0478878499203982 |
| Omelette | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | All - MR Egger | -0.0784227139652444 | 0.0322785738291534 | 0.0317580752173296 |
| Omelette | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | rs2447563 | 0.147704357372066 | 0.0638684343860834 | 0.0207427322151017 |
| Omelette | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | rs75079782 | -0.136441033229722 | 0.068989971775697 | 0.047963270294211 |
| Omelette | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | All - MR Egger | -0.105535263682672 | 0.0433436188292812 | 0.0300560242014033 |
| Omelette | Fractured heel (right) (ukb-b-3499) | All - Inverse variance weighted | -0.0196602287812783 | 0.0084169383912204 | 0.019502014009713 |
| Omelette | Non-cancer illness code, self-reported: joint disorder (ukb-b-8201) | rs2031784 | -0.0254572264060744 | 0.0110724596291031 | 0.0214965212818186 |
| Omelette | Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) | All - Inverse variance weighted | 0.0081324656001897 | 0.0029784512910498 | 0.0063250936836849 |
| Omelette | Heel bone mineral density (BMD) (ukb-e-3148_EAS) | rs17133684 | 7.37108932025882 | 3.536195791549 | 0.0371175576377577 |
| Omelette | Heel bone mineral density (BMD) (ukb-e-3148_EAS) | All - Inverse variance weighted | 1.76384381604605 | 0.624229336100617 | 0.0047187104063457 |
| Omelette | Spondylosis and allied disorders (ukb-e-721_CSA) | rs2291762 | 6.08919439536982 | 2.7553216721677 | 0.0271068373627234 |
| Omelette | Spondylosis and allied disorders (ukb-e-721_CSA) | rs72940321 | 15.6864271534779 | 7.70308668405278 | 0.0417120103726967 |
| Omelette | Spondylosis and allied disorders (ukb-e-721_CSA) | rs73401048 | 9.63201174377667 | 4.67138574076608 | 0.0392155965181266 |
| Omelette | Spondylosis and allied disorders (ukb-e-721_CSA) | All - Inverse variance weighted | 3.96472217095223 | 1.59917015749855 | 0.0131663708416953 |
| Omelette | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_EAS) | rs17133684 | 7.13761590287506 | 3.59252588590191 | 0.046945012927708 |
| Omelette | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_EAS) | rs2291762 | 1.98791027803701 | 0.970680096735509 | 0.0405642957931124 |
| Omelette | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_EAS) | All - Inverse variance weighted | 1.78741060819176 | 0.633796213680825 | 0.0047998794355699 |