ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Sponge pudding | Total body bone mineral density (age 15-30) (ebi-a-GCST005344) | rs1468548 | -7.86683935338418 | 3.01668771952266 | 0.0091133140886449 |
| Sponge pudding | Total body bone mineral density (age 15-30) (ebi-a-GCST005344) | All - Inverse variance weighted | -1.81982597526335 | 0.875190804689847 | 0.0375854050425064 |
| Sponge pudding | Osteoarthritis (hip) (ebi-a-GCST007091) | rs142743017 | 3.33058485069978 | 1.65629084467232 | 0.0443392358133193 |
| Sponge pudding | Osteoarthritis (hip) (ebi-a-GCST007091) | All - MR Egger | 1.71887749728387 | 0.733199017160928 | 0.0332409545728968 |
| Sponge pudding | Neck circumference (BMI adjusted) (ebi-a-GCST90017138) | rs142743017 | -14.3665227613969 | 6.34071342927818 | 0.0234661985738171 |
| Sponge pudding | Neck circumference (BMI adjusted) (ebi-a-GCST90017138) | All - MR Egger | -7.90437503460495 | 3.33314172821323 | 0.0370568937092255 |
| Sponge pudding | Fracture of lower leg or ankle (ebi-a-GCST90038707) | All - Inverse variance weighted | -0.013570742977481 | 0.0052862329921877 | 0.0102527619832162 |
| Sponge pudding | Fracture of lower leg or ankle (ebi-a-GCST90038707) | All - MR Egger | -0.024975450151371 | 0.0112677723541318 | 0.0451052106595335 |
| Sponge pudding | Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) | rs1468548 | -34.4200870895359 | 14.9128838148841 | 0.0209948431671656 |
| Sponge pudding | Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) | rs148036230 | 54.784418824164 | 22.4219592772384 | 0.0145521125824404 |
| Sponge pudding | Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) | rs79889442 | -14.146925957065 | 6.50171342489837 | 0.0295644906187285 |
| Sponge pudding | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | rs112870095 | -22.1044078964454 | 9.37897669724975 | 0.0184329831752736 |
| Sponge pudding | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | All - Inverse variance weighted | -3.63675304252759 | 1.83865745499673 | 0.0479355422930333 |
| Sponge pudding | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | All - MR Egger | -7.86441263213313 | 3.13632917427616 | 0.0262142255231139 |
| Sponge pudding | Other/unspecified synovitis and tenosynovitis (finn-b-M13_TENDOSYNOVITISNAS) | All - Inverse variance weighted | -2.3875126858866 | 1.15150364934848 | 0.0381362787079895 |
| Sponge pudding | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | rs61677937 | 26.8606029538974 | 13.6481594207542 | 0.0490593953600754 |
| Sponge pudding | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | rs72954113 | -40.3744027492376 | 15.7357677215794 | 0.0102946273258569 |
| Sponge pudding | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | rs74631368 | 47.6122770969399 | 21.6344389814339 | 0.0277527922632049 |
| Sponge pudding | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | rs79889442 | 23.1672554380039 | 7.59414718128382 | 0.0022832953135045 |
| Sponge pudding | Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) | rs116805423 | 3.1884476534296 | 1.49602888086643 | 0.033066564924197 |
| Sponge pudding | Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) | All - MR Egger | 1.58696011932658 | 0.717600470923226 | 0.0455267204920784 |
| Sponge pudding | Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) | rs1468548 | 9.61502587635844 | 4.18925185078588 | 0.0217236475668959 |
| Sponge pudding | Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) | All - Inverse variance weighted | 1.97170537140902 | 0.990156323489496 | 0.0464471293480659 |
| Sponge pudding | Ankle and foot (finn-b-Z21_ANKLE_FOOT) | rs112369617 | 65.6314822497481 | 27.7069874948142 | 0.0178473457148809 |
| Sponge pudding | Ankle and foot (finn-b-Z21_ANKLE_FOOT) | rs74631368 | 50.5017612093638 | 23.7671534453658 | 0.0335986914577382 |
| Sponge pudding | Ankle and foot (finn-b-Z21_ANKLE_FOOT) | All - MR Egger | 19.6287004000793 | 7.67529170195961 | 0.0238567333687039 |
| Sponge pudding | Psoriatic arthritis (ieu-b-5116) | rs142743017 | 10.7692030720595 | 4.9437041144425 | 0.0293787070531964 |
| Sponge pudding | Psoriatic arthritis (ieu-b-5116) | rs149738420 | -6.11297536765176 | 3.09113158713848 | 0.0479755461849931 |
| Sponge pudding | Psoriatic arthritis (ieu-b-5116) | All - Inverse variance weighted | -2.01546928109041 | 1.02669440371581 | 0.0496384597844255 |
| Sponge pudding | Heel bone mineral density (BMD), manual entry (ukb-b-11364) | All - MR Egger | -1.16581800969566 | 0.506273089811508 | 0.0384623862859216 |
| Sponge pudding | Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach (ukb-b-13920) | rs61677937 | 0.0475168679716785 | 0.0230325825777721 | 0.0391099465283995 |
| Sponge pudding | Diagnoses - secondary ICD10: M13.99 Arthritis, unspecified (Site unspecified) (ukb-b-15026) | All - Inverse variance weighted | 0.0176837332804475 | 0.0089164666663388 | 0.0473376236630615 |
| Sponge pudding | Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) | All - Inverse variance weighted | -0.0244117917988739 | 0.0109155573415261 | 0.025324146066544 |
| Sponge pudding | Heel bone ultrasound T-score, manual entry (ukb-b-17612) | All - MR Egger | -1.22931133477606 | 0.513522923252627 | 0.032454697295576 |
| Sponge pudding | Ankle spacing width (left) (ukb-e-4100_CSA) | All - Inverse variance weighted | -1.03313767446093 | 0.461755065555066 | 0.0252592340934053 |