ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Unsalted nuts | Heel bone mineral density T score (ebi-a-GCST90025982) | rs62030847 | 0.388931975702209 | 0.158594233239758 | 0.0141918062807117 |
| Unsalted nuts | Heel bone mineral density T score (ebi-a-GCST90025982) | All - Inverse variance weighted | 0.231430865658117 | 0.0700149295290842 | 0.0009482393964056 |
| Unsalted nuts | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | rs4734720 | 0.0390587611300687 | 0.015693385089815 | 0.0128150600649921 |
| Unsalted nuts | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | rs73913809 | 0.0308950808880816 | 0.0156018381571766 | 0.047678749179437 |
| Unsalted nuts | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | All - Inverse variance weighted | 0.0090537181768708 | 0.0044317183568265 | 0.0410587471296771 |
| Unsalted nuts | Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) | All - Inverse variance weighted | -1.2340932451864 | 0.606856941302177 | 0.0419937760338985 |
| Unsalted nuts | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | All - Inverse variance weighted | -3.88024266626579 | 1.72200881581866 | 0.0242387688034959 |
| Unsalted nuts | Cervicalgia (finn-b-M13_CERVICALGIA) | rs117713405 | 5.05253825048225 | 2.23931562488767 | 0.0240526765060468 |
| Unsalted nuts | Cervicalgia (finn-b-M13_CERVICALGIA) | rs117987918 | 12.7142948806443 | 6.19479178616497 | 0.0401291709138709 |
| Unsalted nuts | Cervicalgia (finn-b-M13_CERVICALGIA) | All - Inverse variance weighted | 1.14913777639577 | 0.574843729351124 | 0.0456036181469397 |
| Unsalted nuts | Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) | rs2178664 | -22.1434813998556 | 9.7212194905701 | 0.0227355064363118 |
| Unsalted nuts | Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) | rs2664108 | 18.6604439172104 | 8.37417663034995 | 0.0258583986035682 |
| Unsalted nuts | Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) | All - MR Egger | -15.9575148672007 | 5.71522153814521 | 0.0152584603964254 |
| Unsalted nuts | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | rs4904335 | -10.1907855073027 | 4.51195083529435 | 0.0239069897051225 |
| Unsalted nuts | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | rs62030847 | -10.0831073258156 | 4.92854990404593 | 0.0407704619079876 |
| Unsalted nuts | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | All - Inverse variance weighted | -4.10373638292894 | 1.41797199589384 | 0.0038026102295287 |
| Unsalted nuts | Fracture at wrist and hand level (finn-b-ST19_FRACT_WRIST_HAND_LEVEL) | rs117713405 | -4.14195511783665 | 1.68937133819776 | 0.0142154288467821 |
| Unsalted nuts | Fracture at wrist and hand level (finn-b-ST19_FRACT_WRIST_HAND_LEVEL) | rs77536627 | -4.01921820175746 | 1.96613535201115 | 0.0409315675078425 |
| Unsalted nuts | Fracture at wrist and hand level (finn-b-ST19_FRACT_WRIST_HAND_LEVEL) | All - MR Egger | -2.50134600643245 | 1.11234660085599 | 0.0425084733515143 |
| Unsalted nuts | Injuries to the ankle and foot (finn-b-ST19_INJURI_ANKLE_FOOT) | rs145713169 | 1.89079063790937 | 0.932714904840537 | 0.0426429514726688 |
| Unsalted nuts | Injuries to the ankle and foot (finn-b-ST19_INJURI_ANKLE_FOOT) | All - Inverse variance weighted | 0.69849801163279 | 0.307506910327765 | 0.0231175007878004 |
| Unsalted nuts | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | rs4734720 | 15.4565381672761 | 7.20491530117485 | 0.0319307164620576 |
| Unsalted nuts | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | rs76520208 | 18.9614278354941 | 9.51156950287628 | 0.0462054120803659 |
| Unsalted nuts | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | All - Inverse variance weighted | 5.38862802505286 | 2.16301439797898 | 0.0127291466602469 |
| Unsalted nuts | Open wound of shoulder and upper arm (finn-b-ST19_OPEN_WOUND_SHOUL_UPPER_ARM) | rs62030847 | -16.863332857528 | 7.25603083218347 | 0.0201231511619439 |
| Unsalted nuts | Open wound of shoulder and upper arm (finn-b-ST19_OPEN_WOUND_SHOUL_UPPER_ARM) | All - Inverse variance weighted | -4.71331568610642 | 2.10873581398171 | 0.0254082860739201 |
| Unsalted nuts | Superficial injury of neck (finn-b-ST19_SUPERF_INJURY_NECK) | rs11241419 | -15.0393669317773 | 7.0260980776148 | 0.0323143348817064 |
| Unsalted nuts | Superficial injury of neck (finn-b-ST19_SUPERF_INJURY_NECK) | rs2664108 | 14.7816314425748 | 7.46105578622046 | 0.0475720387701396 |
| Unsalted nuts | Superficial injury of neck (finn-b-ST19_SUPERF_INJURY_NECK) | All - MR Egger | -14.6264435037499 | 5.19765541630734 | 0.0146309234675814 |
| Unsalted nuts | Osteocrin (prot-a-2157) | rs117713405 | 4.01615086924745 | 1.66900303128332 | 0.0161142618885537 |
| Unsalted nuts | Osteocrin (prot-a-2157) | All - Inverse variance weighted | 1.14721394202093 | 0.493200366313835 | 0.0200153178350751 |
| Unsalted nuts | Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) | All - MR Egger | -0.0253234514514979 | 0.0116147393151177 | 0.0482099672587771 |
| Unsalted nuts | Diagnoses - secondary ICD10: M13.99 Arthritis, unspecified (Site unspecified) (ukb-b-15026) | rs2664108 | -0.0298023912839884 | 0.0136720725501826 | 0.0292722490558248 |
| Unsalted nuts | Spondylosis and allied disorders (ukb-e-721_CSA) | rs112734217 | 26.2529462845801 | 12.3495844188066 | 0.0335185688633469 |
| Unsalted nuts | Spondylosis and allied disorders (ukb-e-721_CSA) | All - Inverse variance weighted | 3.6714616561254 | 1.86708873827222 | 0.0492512883753214 |
| Unsalted nuts | Osteoarthrosis (ukb-e-740_CSA) | rs145713169 | -16.9833013035466 | 7.41381545207085 | 0.0219770686594197 |
| Unsalted nuts | Osteoarthrosis (ukb-e-740_CSA) | All - Inverse variance weighted | -2.9777747277767 | 1.23800576174798 | 0.0161592132635539 |