ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Other fish | Osteopontin levels (ebi-a-GCST90010244) | rs34162270 | 11.2369344647956 | 5.36254296848085 | 0.0361311114164849 |
| Other fish | Osteopontin levels (ebi-a-GCST90010244) | rs72838067 | 23.5782612711272 | 9.75172953692831 | 0.0156123264170449 |
| Other fish | Osteopontin levels (ebi-a-GCST90010244) | All - Inverse variance weighted | 2.25268226700231 | 1.10893079959287 | 0.0422144124327858 |
| Other fish | Rheumatoid arthritis (ebi-a-GCST90013534) | rs144345266 | 10.9928881553817 | 4.2834357295108 | 0.0102768641510509 |
| Other fish | Rheumatoid arthritis (ebi-a-GCST90013534) | All - Inverse variance weighted | 0.998225273589878 | 0.461048241657798 | 0.0303784129281359 |
| Other fish | Bone disorder (ebi-a-GCST90038652) | rs80082189 | -0.100504229676618 | 0.0475758708091536 | 0.0346432211081447 |
| Other fish | Joint disorder (ebi-a-GCST90038654) | rs17173732 | -0.239093386964461 | 0.0887355730881625 | 0.0070505328275876 |
| Other fish | Joint disorder (ebi-a-GCST90038654) | All - Inverse variance weighted | -0.0483477520946047 | 0.0233451745839489 | 0.038359214250213 |
| Other fish | Osteoporosis (ebi-a-GCST90038656) | rs61993987 | -0.0851498555329487 | 0.0430653492758066 | 0.048016280818504 |
| Other fish | Osteoporosis (ebi-a-GCST90038656) | All - Inverse variance weighted | -0.0177916556359758 | 0.0089632489599244 | 0.0471493567154899 |
| Other fish | Neck injury (ebi-a-GCST90038700) | rs61747222 | -0.0653018858885713 | 0.0317394567491177 | 0.0396443508055897 |
| Other fish | Benign neoplasm: Short bones of lower limb (finn-b-CD2_BENIGN_BONE_SHORT_LOWER) | rs80082189 | -38.7671584406697 | 18.9671395320569 | 0.0409622709037103 |
| Other fish | Benign neoplasm: Short bones of lower limb (finn-b-CD2_BENIGN_BONE_SHORT_LOWER) | All - Inverse variance weighted | -9.97029214192732 | 3.77160355975704 | 0.0082050029920954 |
| Other fish | Benign neoplasm: Short bones of lower limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_LOWER_EXALLC) | rs80082189 | -38.5465579571495 | 18.9626374813728 | 0.0420764190763515 |
| Other fish | Benign neoplasm: Short bones of lower limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_LOWER_EXALLC) | All - Inverse variance weighted | -9.96145918130609 | 3.76360446038891 | 0.0081260529734675 |
| Other fish | Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) | rs191635022 | 209.372484435812 | 73.6741822800889 | 0.004484970685198 |
| Other fish | Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) | rs4780881 | 33.4709449648379 | 13.1423853315491 | 0.0108717664351235 |
| Other fish | Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) | rs61747222 | 24.900329484907 | 11.6251217603756 | 0.0321981985064125 |
| Other fish | Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) | All - Inverse variance weighted | 11.0453564481197 | 4.24975993465475 | 0.0093481009428559 |
| Other fish | Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) | rs191635022 | 205.94577828325 | 72.8728943112247 | 0.0047119174140017 |
| Other fish | Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) | rs4780881 | 33.5791361785724 | 13.1765509779916 | 0.0108217986104618 |
| Other fish | Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) | rs61747222 | 25.0546923654248 | 11.65173605012 | 0.0315317343597873 |
| Other fish | Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) | All - Inverse variance weighted | 11.1736573849202 | 4.25879696426532 | 0.0086989247954052 |
| Other fish | Pain in joint (finn-b-JOINTPAIN) | rs61993987 | -6.41043507344129 | 3.22844375075485 | 0.0470764773379455 |
| Other fish | Pain in joint (finn-b-JOINTPAIN) | rs72744195 | -6.64154305638265 | 2.79572140977093 | 0.0175199810515024 |
| Other fish | Pain in joint (finn-b-JOINTPAIN) | All - Inverse variance weighted | -0.858431583000398 | 0.411121315942931 | 0.0367955801987017 |
| Other fish | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | rs61993987 | 78.9226752882373 | 33.7593020987207 | 0.0193973506824119 |
| Other fish | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | rs7235226 | 31.0963198478613 | 15.5555885717682 | 0.0456034970548046 |
| Other fish | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | rs72838067 | 106.679333078246 | 35.4043795877259 | 0.0025853600554169 |
| Other fish | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | All - Inverse variance weighted | 13.3534108089703 | 4.61651709736745 | 0.0038215357774462 |
| Other fish | Other shoulder lesions (finn-b-M13_SHOULDERNAS) | rs11775487 | -15.9273001569795 | 7.42084768913988 | 0.0318497525482767 |
| Other fish | Other shoulder lesions (finn-b-M13_SHOULDERNAS) | rs17173732 | 32.8969503597041 | 14.6679116749772 | 0.0249107786592291 |
| Other fish | Other shoulder lesions (finn-b-M13_SHOULDERNAS) | rs61747222 | -9.68760146697965 | 3.89633201858742 | 0.0129065027850669 |
| Other fish | Other shoulder lesions (finn-b-M13_SHOULDERNAS) | All - Inverse variance weighted | -2.90638555019575 | 1.37475291550021 | 0.0345054593648899 |
| Other fish | Pain (limb, back, neck, head abdominally) (finn-b-PAIN) | rs114437011 | -9.61213105561839 | 3.96376538376016 | 0.0153083867547466 |
| Other fish | Pain (limb, back, neck, head abdominally) (finn-b-PAIN) | rs72744195 | -3.60488955763959 | 1.41831720300574 | 0.0110325333029858 |
| Other fish | Pain (limb, back, neck, head abdominally) (finn-b-PAIN) | All - Inverse variance weighted | -0.527196049986459 | 0.233173733215365 | 0.0237618493550208 |
| Other fish | Dislocation, sprain and strain of joints and ligaments of elbow (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ELBOW) | rs117820915 | 6.09865653967087 | 2.73592225080648 | 0.0258069540699998 |
| Other fish | Dislocation, sprain and strain of joints and ligaments of elbow (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ELBOW) | All - MR Egger | 6.09518958828186 | 2.93744354756648 | 0.0493579614825392 |
| Other fish | Fracture of forearm (finn-b-ST19_FRACT_FOREA) | rs144373947 | -6.17709913453734 | 3.01863161446633 | 0.0407244774022174 |
| Other fish | Fracture of forearm (finn-b-ST19_FRACT_FOREA) | rs80082189 | -7.09973392880457 | 2.35907455846138 | 0.0026164191431876 |
| Other fish | Fracture of forearm (finn-b-ST19_FRACT_FOREA) | All - Inverse variance weighted | -0.983324133481392 | 0.464226257258458 | 0.0341581194557172 |
| Other fish | Fracture of rib(s), sternum and thoracic spine (finn-b-ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE) | rs185411372 | -7.68821918364721 | 3.0637773497141 | 0.0120939100676656 |
| Other fish | Fracture of rib(s), sternum and thoracic spine (finn-b-ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE) | rs4780881 | -5.56900037012784 | 2.38590097656806 | 0.019588974578038 |
| Other fish | Fracture of rib(s), sternum and thoracic spine (finn-b-ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE) | All - Inverse variance weighted | -1.92928345274518 | 0.683038201385145 | 0.0047345351324265 |
| Other fish | Fracture of rib(s), sternum and thoracic spine (finn-b-ST19_FRACT_RIBS_STERNUM_THORACIC_SPINE) | All - MR Egger | -2.98311119897134 | 1.35151218672418 | 0.0375472600643964 |
| Other fish | Injury of muscle and tendon at wrist and hand level (finn-b-ST19_INJURY_MUSCLE_TENDON_WRIST_HAND_LEVEL) | rs150868792 | 24.973889537384 | 6.94913750145058 | 0.0003258757664833 |
| Other fish | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | rs72838067 | 45.3835767659309 | 19.7780739137892 | 0.0217537139355348 |
| Other fish | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | rs77082288 | -22.5652755763518 | 9.67625592012225 | 0.0196993495750981 |
| Other fish | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | All - Inverse variance weighted | -6.96027834544337 | 2.67745498490089 | 0.0093335896851877 |
| Other fish | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | rs185411372 | 50.1376160765369 | 17.9967297139007 | 0.0053374516542092 |
| Other fish | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | rs79365677 | 184.831847890671 | 59.2370766488414 | 0.0018072495740773 |
| Other fish | Shoulder region (finn-b-Z21_SHOUL_REGION) | rs61373860 | 56.0268776298817 | 19.7437135088997 | 0.0045438846636543 |
| Other fish | Shoulder region (finn-b-Z21_SHOUL_REGION) | rs7235226 | 41.8480494846995 | 14.069859004264 | 0.0029365320282816 |
| Other fish | Shoulder region (finn-b-Z21_SHOUL_REGION) | All - MR Egger | -15.8942853430499 | 7.56139910495869 | 0.0467026785465154 |
| Other fish | Four-jointed box protein 1 (prot-a-1112) | rs7235226 | -10.2812486071285 | 4.52652274899589 | 0.0231267185700916 |
| Other fish | Bone sialoprotein 2 (prot-a-1396) | rs34162270 | -12.2274926093666 | 4.25446746426083 | 0.0040526277957099 |
| Other fish | Bone sialoprotein 2 (prot-a-1396) | All - MR Egger | 4.48058133723523 | 1.86411590672326 | 0.0251011710507466 |
| Other fish | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | rs61747222 | -0.0847500119764304 | 0.0370624211551666 | 0.0222143270287309 |
| Other fish | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | All - Inverse variance weighted | -0.0150424276206969 | 0.0071068447849436 | 0.0342928545812902 |
| Other fish | Fractured bone site(s): Other bones (ukb-a-441) | rs150868792 | 0.225522721222174 | 0.0890745632897135 | 0.0113465103453226 |
| Other fish | Fractured bone site(s): Other bones (ukb-a-441) | rs185411372 | 0.201267151228727 | 0.0919894917514989 | 0.028674240291832 |
| Other fish | Fractured bone site(s): Other bones (ukb-a-441) | rs34162270 | 0.229959981757194 | 0.0948175336556812 | 0.0152961777653467 |
| Other fish | Fractured bone site(s): Other bones (ukb-a-441) | All - Inverse variance weighted | 0.0405253981078732 | 0.0196155571292389 | 0.038830130331019 |
| Other fish | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | rs116635067 | -0.101960100266171 | 0.0485089283406982 | 0.0355635108266397 |
| Other fish | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | rs185411372 | -0.101652747074177 | 0.0511393527812666 | 0.0468382672757977 |
| Other fish | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | All - Inverse variance weighted | -0.0270196948471352 | 0.0098164274449967 | 0.0059142545626041 |
| Other fish | Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) | rs61373860 | 0.10700233706664 | 0.0431618302749667 | 0.0131715710499895 |
| Other fish | Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) | All - Inverse variance weighted | 0.0771643405884033 | 0.0247695945388102 | 0.0018376740476386 |
| Other fish | Operative procedures - secondary OPCS: Z67.5 Lumbar intervertebral joint (ukb-b-19054) | rs61373860 | -0.0476554340208182 | 0.0217182212114023 | 0.0282166904169215 |
| Other fish | Operative procedures - secondary OPCS: Y76.7 Arthroscopic approach to joint (ukb-b-4455) | rs34162270 | 0.0774297766787374 | 0.0322779556244825 | 0.0164469247567546 |
| Other fish | Operative procedures - secondary OPCS: Y76.7 Arthroscopic approach to joint (ukb-b-4455) | All - Inverse variance weighted | 0.0453374439490359 | 0.0185542253387827 | 0.0145451473955623 |
| Other fish | Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) | All - Inverse variance weighted | -1.4289549691872 | 0.601828949756919 | 0.0175796874525317 |
| Other fish | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA) | All - Inverse variance weighted | -1.38286008847694 | 0.604686712970613 | 0.0222014632276193 |
| Other fish | Internal derangement of knee (ukb-e-835_CSA) | rs150535976 | 17.5669397840002 | 8.24696494423226 | 0.0331625600909956 |
| Other fish | Internal derangement of knee (ukb-e-835_CSA) | rs7235226 | 15.0256783593584 | 7.54750620292094 | 0.046501378323682 |
| Other fish | Internal derangement of knee (ukb-e-835_CSA) | All - Inverse variance weighted | 4.91264578382209 | 2.32694161115296 | 0.0347548791467928 |
| Other fish | Open wounds of head; neck; and trunk (ukb-e-870_CSA) | rs61373860 | -35.1241754136226 | 17.3984657716547 | 0.0435070984134899 |