ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Double crust pastry | Menstruation quality of life impact (stiff neck) (ebi-a-GCST006652) | rs12337889 | 6.5490599033721 | 2.14417614338079 | 0.0022555035221558 |
| Double crust pastry | Menstruation quality of life impact (stiff neck) (ebi-a-GCST006652) | All - Inverse variance weighted | 4.91629491481378 | 1.71606209206042 | 0.0041718038489176 |
| Double crust pastry | Other joint disorder (ebi-a-GCST90038688) | rs1728888 | -0.0520481704492821 | 0.0182105351804287 | 0.0042613886762338 |
| Double crust pastry | Other joint disorder (ebi-a-GCST90038688) | All - Inverse variance weighted | -0.0126026461740411 | 0.0053829659433429 | 0.0192214241056862 |
| Double crust pastry | Benign neoplasm: Long bones of lower limb (finn-b-CD2_BENIGN_BONE_LONG_LOWER) | rs10789657 | -14.0052309758598 | 6.1410949704874 | 0.0225735760916109 |
| Double crust pastry | Benign neoplasm: Long bones of lower limb (finn-b-CD2_BENIGN_BONE_LONG_LOWER) | rs75438658 | 7.62317050284867 | 3.25405891923703 | 0.0191465569597597 |
| Double crust pastry | Benign neoplasm: Long bones of lower limb (finn-b-CD2_BENIGN_BONE_LONG_LOWER) | All - MR Egger | 9.05064893063171 | 3.54818612993817 | 0.0341331039968982 |
| Double crust pastry | Benign neoplasm: Long bones of lower limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_LONG_LOWER_EXALLC) | rs10789657 | -13.9875587601173 | 6.15876718622981 | 0.0231371654025208 |
| Double crust pastry | Benign neoplasm: Long bones of lower limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_LONG_LOWER_EXALLC) | rs75438658 | 7.57762096590526 | 3.25405891923703 | 0.0198766917232723 |
| Double crust pastry | Benign neoplasm: Long bones of lower limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_LONG_LOWER_EXALLC) | All - MR Egger | 9.04394915375844 | 3.50960497830981 | 0.0327732413127168 |
| Double crust pastry | Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) | All - Inverse variance weighted | 7.64516194548986 | 3.23324957673842 | 0.0180522668786656 |
| Double crust pastry | Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) | All - Inverse variance weighted | 7.60469737598923 | 3.23517036804359 | 0.01874152179876 |
| Double crust pastry | Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) | rs116893288 | 13.2261245220648 | 6.46586886664633 | 0.0408026989615522 |
| Double crust pastry | Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) | All - Inverse variance weighted | 4.54973403977493 | 2.22758914029607 | 0.0411071545713961 |
| Double crust pastry | Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) | rs116893288 | 13.1764689191394 | 6.45522838030517 | 0.0412300782670336 |
| Double crust pastry | Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) | All - Inverse variance weighted | 4.49692312181453 | 2.22436333158088 | 0.0432107104885112 |
| Double crust pastry | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | rs184629495 | 33.3160057363924 | 14.8033404820555 | 0.024412563683709 |
| Double crust pastry | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | rs75438658 | -12.2929090302868 | 5.07604039697333 | 0.0154459039270273 |
| Double crust pastry | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | rs1728888 | 10.1225314750095 | 4.44650301065308 | 0.0228151948024688 |
| Double crust pastry | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | All - Inverse variance weighted | 2.78417571381611 | 1.25118039314274 | 0.0260651815543858 |
| Double crust pastry | Spondylosis (finn-b-M13_SPONDYLOSIS) | rs75438658 | 1.86570903320197 | 0.745190424394146 | 0.0122913491068616 |
| Double crust pastry | Spondylosis (finn-b-M13_SPONDYLOSIS) | All - MR Egger | 2.27417801257826 | 0.78933836380917 | 0.0204763247022066 |
| Double crust pastry | Collapsed vertebra, not elsewhere classified (finn-b-M13_VERTEBCOLLAPSE) | All - Inverse variance weighted | -10.3293930517187 | 3.98075433839755 | 0.0094636866328012 |
| Double crust pastry | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | rs11784977 | 2.4904599317132 | 1.17292629041976 | 0.033729753177745 |
| Double crust pastry | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | All - Inverse variance weighted | 0.809470337348204 | 0.370009376867821 | 0.0286912998351384 |
| Double crust pastry | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | rs184629495 | 43.615912480833 | 21.0308265786181 | 0.0380882402304971 |
| Double crust pastry | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | All - Inverse variance weighted | 7.91106987148106 | 3.94144129160991 | 0.0447335320874313 |
| Double crust pastry | Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) | rs12337889 | 7.65711914477389 | 3.64577672828589 | 0.0357050085607774 |
| Double crust pastry | Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) | rs4530350 | 7.53895708191869 | 3.55184121180465 | 0.0337916608409748 |
| Double crust pastry | Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) | All - Inverse variance weighted | 2.5270384665955 | 1.12889767448189 | 0.0251884084291323 |
| Double crust pastry | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | rs4530350 | 24.6713676329764 | 11.4738399930356 | 0.0315372146158521 |
| Double crust pastry | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | All - Inverse variance weighted | 9.11071264793366 | 3.25111005807742 | 0.0050733525292487 |
| Double crust pastry | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | All - Inverse variance weighted | 5.59379700351286 | 2.15106498132403 | 0.0093094007752623 |
| Double crust pastry | Lumbar spine bone mineral density (ieu-a-982) | All - Inverse variance weighted | 0.608945818445603 | 0.240275241769877 | 0.0112650447328347 |
| Double crust pastry | Fractured bone site(s): Wrist (ukb-a-439) | rs10789657 | -0.0653892305517266 | 0.0311894284805429 | 0.0360361730102451 |
| Double crust pastry | Fractured bone site(s): Wrist (ukb-a-439) | rs4530350 | -0.060023940106207 | 0.030303560546705 | 0.0476187146674836 |
| Double crust pastry | Fractured bone site(s): Wrist (ukb-a-439) | All - Inverse variance weighted | -0.0194034904272742 | 0.0090542747003917 | 0.0321115043458515 |
| Double crust pastry | Diagnoses - secondary ICD10: G55.1 Nerve root and plexus compressions in intervertebral disk disorders (ukb-b-1220) | rs1728888 | 0.0319337235252011 | 0.0133086024674723 | 0.0164183831801528 |
| Double crust pastry | Diagnoses - secondary ICD10: G55.1 Nerve root and plexus compressions in intervertebral disk disorders (ukb-b-1220) | All - Inverse variance weighted | 0.0127466815656399 | 0.0057512390720975 | 0.026668459213715 |
| Double crust pastry | Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) | rs4530350 | -0.0492071036824236 | 0.0192222512405328 | 0.010470130317112 |
| Double crust pastry | Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) | All - Inverse variance weighted | -0.0153060750013459 | 0.0077817114538976 | 0.0491913807828504 |
| Double crust pastry | Diagnoses - main ICD10: M75.0 Adhesive capsulitis of shoulder (ukb-b-4921) | All - Inverse variance weighted | -0.0087926792816097 | 0.0043916383203821 | 0.0452695655183974 |
| Double crust pastry | Non-cancer illness code, self-reported: other joint disorder (ukb-b-5316) | rs1728888 | -0.0355870984041433 | 0.0148927533790896 | 0.0168686588214708 |
| Double crust pastry | Non-cancer illness code, self-reported: other joint disorder (ukb-b-5316) | All - Inverse variance weighted | -0.0147311011989798 | 0.0064358410554988 | 0.0220842186887291 |
| Double crust pastry | Operative procedures - secondary OPCS: Z67.6 Lumbosacral joint (ukb-b-7012) | rs10789657 | 0.0232874739334818 | 0.0096485879899621 | 0.0157974012681063 |
| Double crust pastry | Operative procedures - secondary OPCS: Z67.6 Lumbosacral joint (ukb-b-7012) | All - Inverse variance weighted | 0.0103121414535098 | 0.0041427568992684 | 0.0128031704117739 |
| Double crust pastry | Operative procedures - main OPCS: W38.1 Primary total prosthetic replacement of hip joint not using cement (ukb-b-8136) | All - Inverse variance weighted | 0.0128256641819667 | 0.0061495799653249 | 0.0370133941193486 |
| Double crust pastry | Fractured bone site(s): Wrist (ukb-b-9571) | rs10789657 | -0.05412389990457 | 0.0265969497755629 | 0.041854251020582 |
| Double crust pastry | Fractured bone site(s): Wrist (ukb-b-9571) | rs1728888 | -0.0568352351677965 | 0.0264268811318371 | 0.0315030487641952 |
| Double crust pastry | Fractured bone site(s): Wrist (ukb-b-9571) | All - Inverse variance weighted | -0.0324429890513513 | 0.0096961322384556 | 0.0008199461189877 |
| Double crust pastry | Ankle spacing width (ukb-e-3143_AFR) | rs116893288 | 6.18212256421534 | 2.98004554128154 | 0.0380323356120156 |
| Double crust pastry | Ankle spacing width (ukb-e-3143_AFR) | rs12337889 | 5.85399108810133 | 2.62910890893462 | 0.0259735815650479 |
| Double crust pastry | Ankle spacing width (ukb-e-3143_AFR) | rs4530350 | 10.3160094019326 | 4.90119265256377 | 0.0353090924130862 |
| Double crust pastry | Ankle spacing width (ukb-e-3143_AFR) | All - Inverse variance weighted | 3.50213556870904 | 1.22489399274943 | 0.00424799838916 |
| Double crust pastry | Heel bone mineral density (BMD) (left) (ukb-e-4105_CSA) | All - MR Egger | 3.72163962691695 | 1.51003767123774 | 0.0488138524946028 |
| Double crust pastry | Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) | All - MR Egger | 4.2582030653193 | 1.54093942256309 | 0.032707419933154 |
| Double crust pastry | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA) | All - MR Egger | 3.95566822863086 | 1.54950084748997 | 0.0433229764880926 |