ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
Intake (exposure) | Outcome | SNP | b | se | P-value |
---|---|---|---|---|---|
Vegetable pieces | Rheumatoid arthritis (ebi-a-GCST000679) | All - Inverse variance weighted | 1.06556546477363 | 0.531599140008235 | 0.0450215620584378 |
Vegetable pieces | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs75462991 | 0.564409773541647 | 0.280322420170006 | 0.0440693360441445 |
Vegetable pieces | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs75462991 | 0.568344856922445 | 0.284178196263906 | 0.0455046473696421 |
Vegetable pieces | Osteoporosis (ebi-a-GCST90038656) | rs148090673 | -0.0266387792472024 | 0.0103392878942014 | 0.0099817263571494 |
Vegetable pieces | Osteoporosis (ebi-a-GCST90038656) | rs72883121 | -0.0222132009955142 | 0.0102289682717098 | 0.0298860426296552 |
Vegetable pieces | Osteoporosis (ebi-a-GCST90038656) | All - Inverse variance weighted | -0.0056056077839962 | 0.0028222053308389 | 0.0470054753116304 |
Vegetable pieces | Sciatica (ebi-a-GCST90038692) | rs55998069 | -0.0172914949097787 | 0.0080806750651899 | 0.0323662669813635 |
Vegetable pieces | Sciatica (ebi-a-GCST90038692) | All - Inverse variance weighted | -0.0047937899520179 | 0.0021438228692586 | 0.0253455992174646 |
Vegetable pieces | Fracture of lower leg or ankle (ebi-a-GCST90038707) | rs148090673 | 0.0158829704984741 | 0.0060349135300101 | 0.0084922037524472 |
Vegetable pieces | Fracture of lower leg or ankle (ebi-a-GCST90038707) | All - MR Egger | 0.0093648869422246 | 0.0037491888635147 | 0.0280260518998272 |
Vegetable pieces | Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) | rs148090673 | -2.55462868769074 | 1.03112919633774 | 0.0132304214127225 |
Vegetable pieces | Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) | All - MR Egger | -2.60873823074514 | 1.05604736472094 | 0.0311056898878482 |
Vegetable pieces | Spondylosis (finn-b-M13_SPONDYLOSIS) | All - Inverse variance weighted | -0.304289573491126 | 0.154728596699627 | 0.0492291084275126 |
Vegetable pieces | Other/unspecified synovitis and tenosynovitis (finn-b-M13_TENDOSYNOVITISNAS) | rs148090673 | -1.29318413021363 | 0.575381485249237 | 0.0246065104958745 |
Vegetable pieces | Other/unspecified synovitis and tenosynovitis (finn-b-M13_TENDOSYNOVITISNAS) | rs17015391 | -4.00858242672494 | 1.51864368996581 | 0.0083008681374673 |
Vegetable pieces | Drug-induced osteoporosis with pathological fracture (finn-b-OSTPOPATFRACTURE) | All - Inverse variance weighted | -2.4456455679554 | 1.08259944939665 | 0.023880316101134 |
Vegetable pieces | Open wound of shoulder and upper arm (finn-b-ST19_OPEN_WOUND_SHOUL_UPPER_ARM) | rs17015391 | 10.1946172739251 | 4.39471201499934 | 0.0203546014250575 |
Vegetable pieces | Open wound of shoulder and upper arm (finn-b-ST19_OPEN_WOUND_SHOUL_UPPER_ARM) | All - Inverse variance weighted | 1.79627174301598 | 0.89730680919056 | 0.0453010935046025 |
Vegetable pieces | Rheumatoid arthritis (ieu-a-834) | All - Inverse variance weighted | 1.05705490768421 | 0.525027482198427 | 0.0440796586148329 |
Vegetable pieces | Neck/shoulder pain for 3+ months (ukb-a-341) | rs72883121 | 0.213804563270294 | 0.0943759407460396 | 0.0234846968690645 |
Vegetable pieces | Neck/shoulder pain for 3+ months (ukb-a-341) | rs78111513 | -0.204136373127812 | 0.0955276296057253 | 0.0326032464564393 |
Vegetable pieces | Neck/shoulder pain for 3+ months (ukb-a-341) | All - MR Egger | -0.142898417666167 | 0.0542927677726354 | 0.0218948139296914 |
Vegetable pieces | Fractured bone site(s): Arm (ukb-a-440) | rs17015391 | -0.0222402681411244 | 0.0098964615402987 | 0.0246211827735879 |
Vegetable pieces | Fractured bone site(s): Arm (ukb-a-440) | All - Inverse variance weighted | -0.0054364496726456 | 0.0026258300927931 | 0.0384173589066118 |
Vegetable pieces | Fractured bone site(s): Arm (ukb-a-440) | All - MR Egger | -0.013294385256768 | 0.0056054814155124 | 0.0352936236161581 |
Vegetable pieces | Pain type(s) experienced in last month: Knee pain (ukb-a-476) | rs111613235 | -0.0901007730288022 | 0.0402625786928972 | 0.0252321974525154 |
Vegetable pieces | Pain type(s) experienced in last month: Knee pain (ukb-a-476) | All - Inverse variance weighted | -0.0286126387560695 | 0.0107217309152214 | 0.0076154828323738 |
Vegetable pieces | Diagnoses - main ICD10: M25 Other joint disorders not elsewhere classified (ukb-a-568) | rs75462991 | 0.0239368137216026 | 0.0113092912091477 | 0.0342970553112005 |
Vegetable pieces | Diagnoses - main ICD10: M25 Other joint disorders not elsewhere classified (ukb-a-568) | rs75848007 | 0.0301119709681922 | 0.0117398923713962 | 0.0103197411633645 |
Vegetable pieces | Diagnoses - main ICD10: M25 Other joint disorders not elsewhere classified (ukb-a-568) | All - MR Egger | 0.0181841651580242 | 0.0066959864106239 | 0.0187571396335133 |
Vegetable pieces | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | rs142991386 | -0.0273145456779147 | 0.0124825187667577 | 0.0286532982830553 |
Vegetable pieces | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | All - Inverse variance weighted | -0.0070034428947882 | 0.0032357088097362 | 0.0304318925066697 |
Vegetable pieces | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | All - MR Egger | -0.0170965311584815 | 0.0069070794431151 | 0.0292128981589186 |
Vegetable pieces | Operative procedures - secondary OPCS: Z81.4 Shoulder joint (ukb-b-11427) | rs55998069 | 0.0155762637887362 | 0.0074695127637906 | 0.0370409987219253 |
Vegetable pieces | Operative procedures - secondary OPCS: Z81.4 Shoulder joint (ukb-b-11427) | rs585477 | 0.0150852262631926 | 0.007534854521118 | 0.0452783442314372 |
Vegetable pieces | Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach (ukb-b-13920) | All - Inverse variance weighted | -0.0074646420125716 | 0.0031873085116742 | 0.0191812715580384 |
Vegetable pieces | Diagnoses - secondary ICD10: M13.99 Arthritis, unspecified (Site unspecified) (ukb-b-15026) | rs72883121 | 0.0160384793073129 | 0.0064039582122472 | 0.0122637273976219 |
Vegetable pieces | Diagnoses - secondary ICD10: M13.99 Arthritis, unspecified (Site unspecified) (ukb-b-15026) | All - Inverse variance weighted | 0.0064478272730174 | 0.0028818045821245 | 0.0252584479520515 |
Vegetable pieces | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | All - Inverse variance weighted | -0.0218520244114027 | 0.0091819800427607 | 0.0173182063314117 |
Vegetable pieces | Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe (ukb-b-17501) | rs585477 | 0.0113015908112782 | 0.0048409780982125 | 0.0195660187242514 |
Vegetable pieces | Operative procedures - secondary OPCS: Z86.4 Metatarsophalangeal joint of great toe (ukb-b-17501) | All - Inverse variance weighted | 0.0060213299726425 | 0.0027177403766009 | 0.0267213203418013 |
Vegetable pieces | Diagnoses - main ICD10: M25.56 Pain in joint (Lower leg) (ukb-b-2083) | All - Inverse variance weighted | -0.0060412939276123 | 0.002832450063042 | 0.0329340546740282 |
Vegetable pieces | Diagnoses - main ICD10: M75.0 Adhesive capsulitis of shoulder (ukb-b-4921) | rs585477 | 0.0089916965100072 | 0.0041230795958415 | 0.0291966956084065 |
Vegetable pieces | Diagnoses - main ICD10: M75.0 Adhesive capsulitis of shoulder (ukb-b-4921) | All - Inverse variance weighted | 0.0068150315438412 | 0.0029027597292267 | 0.0188858417578137 |
Vegetable pieces | Operation code: shoulder surgery (ukb-b-5935) | rs585477 | 0.0298240986784698 | 0.0103598178996869 | 0.003991602610961 |
Vegetable pieces | Operation code: shoulder surgery (ukb-b-5935) | All - Inverse variance weighted | 0.0105552063415285 | 0.0041429135681978 | 0.010841276412797 |
Vegetable pieces | Fractured heel (left) (ukb-b-8221) | rs116353880 | 0.0393572003807014 | 0.0144986821875686 | 0.0066368608637356 |
Vegetable pieces | Fractured heel (left) (ukb-b-8221) | rs55998069 | -0.0385293755572384 | 0.0144689867680359 | 0.0077471853957149 |
Vegetable pieces | Fractured heel (left) (ukb-b-8221) | All - MR Egger | 0.0247485000407239 | 0.0091903225709335 | 0.0195651026566366 |
Vegetable pieces | Diagnoses - main ICD10: M13 Other arthritis (ukb-d-M13) | rs75848007 | 0.011254367288703 | 0.0054694406104123 | 0.0396207081002758 |
Vegetable pieces | Diagnoses - main ICD10: M13 Other arthritis (ukb-d-M13) | All - MR Egger | 0.007761376831218 | 0.003127841883757 | 0.0288847286926599 |
Vegetable pieces | Other specific joint derangements/joint disorders (ukb-d-M13_JOINTOTH) | All - MR Egger | 0.0197717016203532 | 0.0079314424059888 | 0.028285178568037 |
Vegetable pieces | Diagnoses - main ICD10: M25 Other joint disorders, not elsewhere classified (ukb-d-M25) | All - MR Egger | 0.0229315496499198 | 0.0077647697850116 | 0.012070404385673 |
Vegetable pieces | Other arthritis (FG) (ukb-d-RHEU_ARTHRITIS_OTH) | rs75848007 | 0.011254367288703 | 0.0054694406104123 | 0.0396207081002758 |
Vegetable pieces | Other arthritis (FG) (ukb-d-RHEU_ARTHRITIS_OTH) | All - MR Egger | 0.007761376831218 | 0.003127841883757 | 0.0288847286926599 |
Vegetable pieces | Knee pain for 3+ months (ukb-e-3773_AFR) | rs12435874 | 5.38464347485451 | 2.6700793753548 | 0.0437309599215741 |
Vegetable pieces | Knee pain for 3+ months (ukb-e-3773_AFR) | All - Inverse variance weighted | 5.60177894448541 | 1.73557380211036 | 0.0012482310687219 |