ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Fried potatoes (ukb-b-12836)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Fried potatoes (👉 📊) Total body bone mineral density (age 45-60) (ebi-a-GCST005350) MR Egger 19 -0.544401728 0.225039154 0.027057028
Fried potatoes (👉 📊) Heel bone mineral density (ebi-a-GCST006288) MR Egger 19 0.181141357 0.080689398 0.038367155
Fried potatoes (👉 📊) Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) Inverse variance weighted 17 0.208073767 0.059567333 0.000477474
Fried potatoes (👉 📊) Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) Inverse variance weighted 17 0.208597578 0.059499814 0.000455147
Fried potatoes (👉 📊) Fractures (ebi-a-GCST90038703) Inverse variance weighted 19 -0.004347101 0.002052304 0.034161863
Fried potatoes (👉 📊) Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) Weighted median 16 1.619499266 0.816660773 0.047359093
Fried potatoes (👉 📊) Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) Inverse variance weighted 16 1.639231515 0.571410732 0.004121043
Fried potatoes (👉 📊) Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) Weighted median 16 4.589628067 2.013468305 0.022639511
Fried potatoes (👉 📊) Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) Inverse variance weighted 16 3.649048619 1.62976567 0.025155785
Fried potatoes (👉 📊) Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) Inverse variance weighted 16 1.071723356 0.479340916 0.025363106
Fried potatoes (👉 📊) Other shoulder lesions (finn-b-M13_SHOULDERNAS) Weighted median 16 1.109843766 0.492285223 0.024166424
Fried potatoes (👉 📊) Other/unspecified synovitis and tenosynovitis (finn-b-M13_TENDOSYNOVITISNAS) Weighted median 16 0.770432042 0.359373567 0.032047356
Fried potatoes (👉 📊) Other/unspecified synovitis and tenosynovitis (finn-b-M13_TENDOSYNOVITISNAS) Inverse variance weighted 16 0.656316405 0.268648673 0.014564581
Fried potatoes (👉 📊) Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) MR Egger 16 0.539524617 0.211586873 0.023122034
Fried potatoes (👉 📊) Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) Weighted median 16 3.580070896 1.752335361 0.041049628
Fried potatoes (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot (finn-b-ST19_BURN_CORROSION_HIP_LOWER_LIMB_ANKLE_FOOT) Weighted median 16 -1.703046174 0.854223156 0.046187222
Fried potatoes (👉 📊) Burn and corrosion of hip and lower limb, except ankle and foot (finn-b-ST19_BURN_CORROSION_HIP_LOWER_LIMB_ANKLE_FOOT) Inverse variance weighted 16 -1.418507307 0.702581982 0.043488065
Fried potatoes (👉 📊) Dislocation, sprain and strain of joints and ligaments of head (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_HEAD) Weighted median 16 1.466754189 0.714488348 0.040084849
Fried potatoes (👉 📊) Dislocation, sprain and strain of joints and ligaments of head (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_HEAD) Inverse variance weighted 16 1.00444488 0.493217809 0.041698788
Fried potatoes (👉 📊) Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) Weighted median 16 0.556218705 0.246975371 0.024314554
Fried potatoes (👉 📊) Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) Inverse variance weighted 16 0.463679098 0.188047397 0.013672423
Fried potatoes (👉 📊) Injury of muscle and tendon at hip and thigh level (finn-b-ST19_INJURY_MUSCLE_TENDON_HIP_THIGH_LEVEL) Weighted median 16 1.368103935 0.522697527 0.008860472
Fried potatoes (👉 📊) Injury of muscle and tendon at hip and thigh level (finn-b-ST19_INJURY_MUSCLE_TENDON_HIP_THIGH_LEVEL) Inverse variance weighted 16 0.993332313 0.418411051 0.017593763
Fried potatoes (👉 📊) Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) Inverse variance weighted 16 0.675717903 0.326887453 0.038722182
Fried potatoes (👉 📊) Open wound of wrist and hand (finn-b-ST19_OPEN_WOUND_WRIST_HAND) Inverse variance weighted 16 -0.301393653 0.148096068 0.04183854
Fried potatoes (👉 📊) Bone morphogenetic protein 7 (prot-a-257) Inverse variance weighted 19 -0.476741027 0.189203913 0.011744797
Fried potatoes (👉 📊) Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) Inverse variance weighted 19 -0.000866186 0.000398939 0.029914141
Fried potatoes (👉 📊) Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) MR Egger 11 -0.046923066 0.014418133 0.009926483
Fried potatoes (👉 📊) Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) Inverse variance weighted 19 0.011534605 0.005086679 0.02335297
Fried potatoes (👉 📊) Fractured bone site(s): Other bones (ukb-b-17738) Inverse variance weighted 17 0.009045289 0.0041592 0.029647601
Fried potatoes (👉 📊) Ankle spacing width (ukb-b-4080) MR Egger 19 -0.10758384 0.045467343 0.030113605
Fried potatoes (👉 📊) Operation code: shoulder surgery (ukb-b-5935) MR Egger 11 -0.034922377 0.014700767 0.041529631
Fried potatoes (👉 📊) Ankle spacing width (right) (ukb-b-8607) Inverse variance weighted 19 0.077709676 0.034572822 0.024594692
Fried potatoes (👉 📊) Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) Inverse variance weighted 19 -0.00211008 0.001068777 0.048348216
Fried potatoes (👉 📊) Diagnoses - main ICD10: S02 Fracture of skull and facial bones (ukb-d-S02) MR Egger 19 -0.007466072 0.002772217 0.015392658
Fried potatoes (👉 📊) Diagnoses - main ICD10: S62 Fracture at wrist and hand level (ukb-d-S62) MR Egger 19 0.008952244 0.003082953 0.009882896
Fried potatoes (👉 📊) Diagnoses - main ICD10: S62 Fracture at wrist and hand level (ukb-d-S62) Inverse variance weighted 19 0.002860051 0.001331086 0.031661434
Fried potatoes (👉 📊) Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) Inverse variance weighted 12 -1.655833254 0.657647406 0.011808596
Fried potatoes (👉 📊) Internal derangement of knee (ukb-e-835_CSA) Inverse variance weighted 13 1.187319597 0.536514511 0.026895977
Fried potatoes (👉 📊) M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_CSA) MR Egger 13 3.491622125 1.38343667 0.028279876

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Fried potatoes Total body bone mineral density (age 45-60) (ebi-a-GCST005350) rs115451005 -1.3365501811564 0.462491443073481 0.0038537457017563
Fried potatoes Total body bone mineral density (age 45-60) (ebi-a-GCST005350) All - MR Egger -0.544401727574596 0.225039154361164 0.0270570278474262
Fried potatoes Heel bone mineral density (ebi-a-GCST006288) rs10495468 -0.354598441112542 0.117636817986737 0.0025753125256224
Fried potatoes Heel bone mineral density (ebi-a-GCST006288) rs182009726 0.399642783377242 0.121137743859039 0.0009700318880081
Fried potatoes Heel bone mineral density (ebi-a-GCST006288) rs4669886 -0.244425222133031 0.117135383508179 0.0369161745059633
Fried potatoes Heel bone mineral density (ebi-a-GCST006288) All - MR Egger 0.181141356695895 0.0806893980797278 0.0383671552997377
Fried potatoes Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) rs10495468 0.552044828397779 0.257003571873572 0.0317133981347132
Fried potatoes Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) rs10742742 0.538987358233946 0.246040304095976 0.0284773753959563
Fried potatoes Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) rs72864648 0.624274233554916 0.237204087707114 0.0084933301564041
Fried potatoes Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) rs9596491 0.553398218818996 0.258686633975848 0.0324145390020211
Fried potatoes Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) All - Inverse variance weighted 0.208073767380675 0.059567333458975 0.0004774742479608
Fried potatoes Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) rs10495468 0.55191330592128 0.256846437125334 0.0316497381313929
Fried potatoes Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) rs10742742 0.537944263520946 0.244973638151799 0.028097157955874
Fried potatoes Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) rs72864648 0.621079472169858 0.23498759797599 0.0082167546913386
Fried potatoes Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) rs9596491 0.552232264679859 0.257479609584529 0.0319719485445571
Fried potatoes Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) All - Inverse variance weighted 0.208597578441079 0.0594998136842089 0.0004551471454146
Fried potatoes Fractures (ebi-a-GCST90038703) All - Inverse variance weighted -0.0043471009708937 0.0020523044994126 0.0341618630519684
Fried potatoes Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) rs60152323 4.71771687459656 2.03130586691047 0.0202057901616774
Fried potatoes Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) All - Inverse variance weighted 1.63923151473354 0.571410731669043 0.0041210427134379
Fried potatoes Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) rs11046610 20.9146210548916 7.10513132469763 0.0032442541553337
Fried potatoes Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) rs140724278 10.5130782652757 4.87191431805458 0.0309360168022814
Fried potatoes Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) All - Inverse variance weighted 3.64904861856164 1.62976566985091 0.0251557850582744
Fried potatoes Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) rs4669886 4.00669859108146 2.0206493758131 0.0473812024930164
Fried potatoes Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) All - Inverse variance weighted 1.07172335618071 0.479340915939448 0.0253631063997545
Fried potatoes Other/unspecified synovitis and tenosynovitis (finn-b-M13_TENDOSYNOVITISNAS) All - Inverse variance weighted 0.656316404620346 0.268648673321725 0.0145645811714705
Fried potatoes Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs76068234 0.759928092825625 0.328485046576238 0.020698853500684
Fried potatoes Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) All - MR Egger 0.539524617457342 0.211586872584504 0.0231220344521011
Fried potatoes Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) rs140724278 9.03689537796411 4.43161340149314 0.0414312116038964
Fried potatoes Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) rs7707187 8.93524550518504 4.1285879257317 0.0304461137456455
Fried potatoes Burn and corrosion of hip and lower limb, except ankle and foot (finn-b-ST19_BURN_CORROSION_HIP_LOWER_LIMB_ANKLE_FOOT) All - Inverse variance weighted -1.41850730689214 0.702581982293702 0.0434880650179636
Fried potatoes Dislocation, sprain and strain of joints and ligaments of head (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_HEAD) All - Inverse variance weighted 1.00444488018062 0.493217809401156 0.0416987877961929
Fried potatoes Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) rs117525941 1.74467814010211 0.888265970130237 0.0495139346183294
Fried potatoes Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) rs4669886 1.93414897445124 0.764663548038863 0.0114253897844285
Fried potatoes Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) All - Inverse variance weighted 0.463679097573799 0.18804739699692 0.0136724231968154
Fried potatoes Injury of muscle and tendon at hip and thigh level (finn-b-ST19_INJURY_MUSCLE_TENDON_HIP_THIGH_LEVEL) rs76068234 2.71939859454159 1.27144958326524 0.0324504531657523
Fried potatoes Injury of muscle and tendon at hip and thigh level (finn-b-ST19_INJURY_MUSCLE_TENDON_HIP_THIGH_LEVEL) rs7707187 3.00155747739575 1.28671238044105 0.0196621203708713
Fried potatoes Injury of muscle and tendon at hip and thigh level (finn-b-ST19_INJURY_MUSCLE_TENDON_HIP_THIGH_LEVEL) All - Inverse variance weighted 0.993332312705016 0.418411050930676 0.0175937626719881
Fried potatoes Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) All - Inverse variance weighted 0.675717902867521 0.326887452954818 0.0387221819472293
Fried potatoes Open wound of wrist and hand (finn-b-ST19_OPEN_WOUND_WRIST_HAND) All - Inverse variance weighted -0.301393652741025 0.148096068264068 0.0418385403733795
Fried potatoes Bone morphogenetic protein 7 (prot-a-257) rs182009726 -1.8380905255869 0.930189708178983 0.0481504351747343
Fried potatoes Bone morphogenetic protein 7 (prot-a-257) All - Inverse variance weighted -0.476741026789371 0.189203912813523 0.0117447966601357
Fried potatoes Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) rs117117106 -0.0054470469920178 0.0017675072044537 0.0020577520664996
Fried potatoes Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) All - Inverse variance weighted -0.0008661861976446 0.0003989388716839 0.0299141408051032
Fried potatoes Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) rs2906294 -0.0206357485938552 0.0069648720493776 0.0030482248848991
Fried potatoes Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) rs4669886 0.0181404143715227 0.0087087912087912 0.0372511996579162
Fried potatoes Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) All - MR Egger -0.046923066114091 0.0144181332157971 0.0099264829057559
Fried potatoes Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs10495468 0.051829200758677 0.0200104179645858 0.0095945030211896
Fried potatoes Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs4669886 0.047504636421513 0.0201355980291749 0.0183125843388403
Fried potatoes Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs7707187 0.0432807462931807 0.0189010180301729 0.0220292460590959
Fried potatoes Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) All - Inverse variance weighted 0.0115346045456348 0.005086678518629 0.0233529700162598
Fried potatoes Fractured bone site(s): Other bones (ukb-b-17738) rs10495468 0.0344480555440185 0.0162276584845842 0.0337707072586231
Fried potatoes Fractured bone site(s): Other bones (ukb-b-17738) rs117117106 -0.0331745190304474 0.0159815618339562 0.0379124930478068
Fried potatoes Fractured bone site(s): Other bones (ukb-b-17738) All - Inverse variance weighted 0.0090452889016474 0.0041591995918682 0.029647601333421
Fried potatoes Ankle spacing width (ukb-b-4080) rs10495468 0.224889244230317 0.0787338538854508 0.0042858015034324
Fried potatoes Ankle spacing width (ukb-b-4080) rs117117106 -0.186884949072529 0.077550572974954 0.0159592491807718
Fried potatoes Ankle spacing width (ukb-b-4080) rs4669886 0.283323760622249 0.0792059955158192 0.0003474944905188
Fried potatoes Ankle spacing width (ukb-b-4080) rs9596491 0.200608611522273 0.0792540098623733 0.0113669487476166
Fried potatoes Ankle spacing width (ukb-b-4080) All - MR Egger -0.107583839979699 0.0454673427244927 0.0301136054903615
Fried potatoes Operation code: shoulder surgery (ukb-b-5935) rs72864648 -0.0223036015477726 0.008069748983034 0.0057123232378986
Fried potatoes Operation code: shoulder surgery (ukb-b-5935) All - MR Egger -0.0349223770608066 0.0147007669074492 0.0415296307376255
Fried potatoes Ankle spacing width (right) (ukb-b-8607) rs10742742 0.300828515229183 0.103737259343148 0.0037327212136792
Fried potatoes Ankle spacing width (right) (ukb-b-8607) rs8111128 0.483207270264168 0.104924221043125 4.11876282253466e-06
Fried potatoes Ankle spacing width (right) (ukb-b-8607) All - Inverse variance weighted 0.0777096761846439 0.0345728221817536 0.0245946915554071
Fried potatoes Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) rs7707187 -0.0085887819971349 0.0043169200363797 0.0466391562128985
Fried potatoes Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) All - Inverse variance weighted -0.0021100803039745 0.0010687766369104 0.0483482161724488
Fried potatoes Diagnoses - main ICD10: S02 Fracture of skull and facial bones (ukb-d-S02) rs10495468 0.0165455621547535 0.0050535088812282 0.0010600883731785
Fried potatoes Diagnoses - main ICD10: S02 Fracture of skull and facial bones (ukb-d-S02) rs182009726 -0.0104721232843126 0.0050700688429539 0.0388776527744444
Fried potatoes Diagnoses - main ICD10: S02 Fracture of skull and facial bones (ukb-d-S02) All - MR Egger -0.0074660722295385 0.0027722174477932 0.0153926579430144
Fried potatoes Diagnoses - main ICD10: S62 Fracture at wrist and hand level (ukb-d-S62) rs140724278 0.0104312497190655 0.0052919470903362 0.0487061114579318
Fried potatoes Diagnoses - main ICD10: S62 Fracture at wrist and hand level (ukb-d-S62) rs60152323 0.0115888339368459 0.005264837651508 0.0277235712885308
Fried potatoes Diagnoses - main ICD10: S62 Fracture at wrist and hand level (ukb-d-S62) All - Inverse variance weighted 0.0028600505522987 0.0013310862462278 0.0316614344916945
Fried potatoes Diagnoses - main ICD10: S62 Fracture at wrist and hand level (ukb-d-S62) All - MR Egger 0.0089522437584649 0.003082953143385 0.0098828962743065
Fried potatoes Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs2906294 -5.16594220259894 1.86672142930486 0.0056507484022125
Fried potatoes Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) All - Inverse variance weighted -1.65583325399074 0.657647405823547 0.0118085963148647
Fried potatoes Internal derangement of knee (ukb-e-835_CSA) All - Inverse variance weighted 1.18731959703855 0.536514511376767 0.0268959773110772
Fried potatoes M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_CSA) rs117525941 4.0508932715673 1.60543152798129 0.0116278141736561
Fried potatoes M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_CSA) rs72864648 4.673082647088 1.83926976882627 0.0110622208652742
Fried potatoes M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_CSA) All - MR Egger 3.49162212467376 1.38343667012654 0.0282798762517444