ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Snackpot (ukb-b-12912)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Snackpot (👉 📊) Rheumatoid Arthritis (bbj-a-74) Inverse variance weighted 86 2.33763479 0.96264326 0.015167697
Snackpot (👉 📊) Rheumatoid arthritis (ebi-a-GCST002318) Inverse variance weighted 71 2.19862816 1.086570214 0.043026047
Snackpot (👉 📊) Osteoarthritis (self-reported) (ebi-a-GCST005811) MR Egger 120 3.565055735 1.3201905 0.007944266
Snackpot (👉 📊) Rheumatoid arthritis (ebi-a-GCST90013534) Simple mode 76 4.993671118 1.858255292 0.008867994
Snackpot (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) MR Egger 116 21.77009387 9.728361534 0.027177606
Snackpot (👉 📊) Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) MR Egger 116 21.76020078 9.725442357 0.02720084
Snackpot (👉 📊) Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) MR Egger 116 17.57261825 7.595507693 0.022484827
Snackpot (👉 📊) Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) MR Egger 116 13.99855968 6.235676982 0.026702886
Snackpot (👉 📊) Chondromalacia (finn-b-M13_CHONDROMALACIA) MR Egger 116 -18.50156568 7.943840669 0.021618279
Snackpot (👉 📊) Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) MR Egger 116 -13.95142934 5.63632278 0.014784326
Snackpot (👉 📊) Gluteal tendinitis (finn-b-M13_GLUTEALTEND) MR Egger 116 18.03422921 8.677045223 0.039918356
Snackpot (👉 📊) Osteonecrosis (finn-b-M13_OSTEONECROSIS) MR Egger 116 15.02239326 6.42232252 0.021072249
Snackpot (👉 📊) Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) MR Egger 116 2.71351953 1.03289435 0.009795913
Snackpot (👉 📊) Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) Weighted median 116 1.858784895 0.783817956 0.017718456
Snackpot (👉 📊) Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) Weighted mode 116 2.425401001 1.08732829 0.027647483
Snackpot (👉 📊) Rheumatoid arthritis (ieu-a-831) Inverse variance weighted 12 3.304445937 1.544003143 0.032340155
Snackpot (👉 📊) Psoriatic arthritis (ieu-b-5116) MR Egger 91 -9.648962626 3.942207311 0.01634428
Snackpot (👉 📊) Psoriatic arthritis (ieu-b-5116) Weighted median 91 -4.472123875 1.982972438 0.024116841
Snackpot (👉 📊) Psoriatic arthritis (ieu-b-5116) Inverse variance weighted 91 -4.288251729 1.459534002 0.003302342
Snackpot (👉 📊) Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) MR Egger 120 1.16770395 0.508506054 0.023420719
Snackpot (👉 📊) Pain type(s) experienced in last month: Knee pain (ukb-a-476) Inverse variance weighted 120 -0.103962681 0.048556166 0.032267512
Snackpot (👉 📊) Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) Weighted median 9 -0.10005606 0.049505456 0.043268197
Snackpot (👉 📊) Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach (ukb-b-13920) Inverse variance weighted 2 -0.14072371 0.071216081 0.04815361
Snackpot (👉 📊) Operation code: knee surgery (not replacement) (ukb-b-1508) MR Egger 28 0.200164692 0.085936315 0.027886394
Snackpot (👉 📊) Ankle spacing width (ukb-b-4080) Weighted median 123 -0.315560658 0.151675818 0.037480228
Snackpot (👉 📊) Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) Weighted median 99 0.022932907 0.011546262 0.047013802
Snackpot (👉 📊) Other joint disorders (ukb-d-M13_OTHERJOINT) MR Egger 121 0.166832324 0.08176972 0.04353659
Snackpot (👉 📊) Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) Weighted median 77 -0.024322439 0.012238979 0.046889925
Snackpot (👉 📊) Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) Inverse variance weighted 77 -0.015380255 0.007635964 0.043989971
Snackpot (👉 📊) Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) MR Egger 121 -0.068433664 0.030738332 0.027874569
Snackpot (👉 📊) Fractured/broken bones in last 5 years (ukb-e-2463_CSA) MR Egger 49 -19.42864189 8.104547458 0.020545849
Snackpot (👉 📊) Fractured/broken bones in last 5 years (ukb-e-2463_CSA) Inverse variance weighted 49 -7.734613472 3.398073275 0.022835467
Snackpot (👉 📊) Heel bone mineral density (BMD) (ukb-e-3148_CSA) Weighted median 49 -4.378075881 2.152677776 0.041973647
Snackpot (👉 📊) Neck/shoulder pain for 3+ months (ukb-e-3404_CSA) Weighted median 50 -9.506662543 4.729721448 0.044432925
Snackpot (👉 📊) Neck/shoulder pain for 3+ months (ukb-e-3404_CSA) Inverse variance weighted 50 -7.925220702 3.236543317 0.014338546
Snackpot (👉 📊) Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) Weighted median 26 5.899232285 2.637089552 0.02528478
Snackpot (👉 📊) Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) Inverse variance weighted 26 3.920111251 1.810690608 0.03038912
Snackpot (👉 📊) Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) Weighted mode 26 6.309664794 2.710132507 0.028288055
Snackpot (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) Weighted median 26 5.788065768 2.648969178 0.028886961
Snackpot (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) Inverse variance weighted 26 3.766797119 1.798487007 0.03622209
Snackpot (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) Weighted mode 26 6.250123846 2.661395099 0.027064456
Snackpot (👉 📊) M75 Shoulder lesions (ukb-e-M75_CSA) Weighted median 50 13.44157629 6.25020989 0.031509366

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Snackpot Rheumatoid Arthritis (bbj-a-74) rs116374832 23.5603027937931 10.9687219382831 0.0317174632889183
Snackpot Rheumatoid Arthritis (bbj-a-74) rs117541068 23.7664849898139 11.7110464209774 0.0424168057474799
Snackpot Rheumatoid Arthritis (bbj-a-74) rs141954310 -62.5671620914628 27.4942605411701 0.0228672971377451
Snackpot Rheumatoid Arthritis (bbj-a-74) rs150981940 -28.1460710680321 12.3655775488901 0.0228362508071837
Snackpot Rheumatoid Arthritis (bbj-a-74) rs59914248 11.9882783413533 4.13780955507338 0.0037644685172929
Snackpot Rheumatoid Arthritis (bbj-a-74) rs76868724 23.1283570763673 9.43719282901961 0.0142552349945355
Snackpot Rheumatoid Arthritis (bbj-a-74) rs79505368 34.9468643737928 14.5988939564192 0.0166747388313667
Snackpot Rheumatoid Arthritis (bbj-a-74) All - Inverse variance weighted 2.33763479002407 0.962643259810911 0.0151676965892776
Snackpot Rheumatoid arthritis (ebi-a-GCST002318) rs116374832 23.4086121671408 11.1132791191453 0.0351727372399665
Snackpot Rheumatoid arthritis (ebi-a-GCST002318) rs117541068 23.8610643259423 11.8167114148006 0.0434597490956357
Snackpot Rheumatoid arthritis (ebi-a-GCST002318) rs141954310 -62.3686514591742 27.1780691478702 0.0217437060583078
Snackpot Rheumatoid arthritis (ebi-a-GCST002318) rs150981940 -28.9141818369157 12.8459227694183 0.0243953523134799
Snackpot Rheumatoid arthritis (ebi-a-GCST002318) rs59914248 11.8833919149379 4.33917548059601 0.0061695946435249
Snackpot Rheumatoid arthritis (ebi-a-GCST002318) rs76868724 22.3891370997432 10.0155303718447 0.0253883463270529
Snackpot Rheumatoid arthritis (ebi-a-GCST002318) rs79505368 35.1079971504322 14.4461042442403 0.015087395955155
Snackpot Rheumatoid arthritis (ebi-a-GCST002318) All - Inverse variance weighted 2.19862815974153 1.08657021412667 0.0430260474743969
Snackpot Osteoarthritis (self-reported) (ebi-a-GCST005811) rs112869543 16.7729797125779 5.39737514413889 0.0018860172805377
Snackpot Osteoarthritis (self-reported) (ebi-a-GCST005811) rs147606020 -18.0778440973587 7.65404102337837 0.0181830541448584
Snackpot Osteoarthritis (self-reported) (ebi-a-GCST005811) rs41303053 -19.0124955095779 7.45324621105469 0.0107444746465671
Snackpot Osteoarthritis (self-reported) (ebi-a-GCST005811) All - MR Egger 3.56505573492567 1.32019049970446 0.0079442658047179
Snackpot Rheumatoid arthritis (ebi-a-GCST90013534) rs116374832 23.5613518299387 11.119783143248 0.0341016303619169
Snackpot Rheumatoid arthritis (ebi-a-GCST90013534) rs117541068 23.7647715960434 11.8738188291695 0.0453446704947177
Snackpot Rheumatoid arthritis (ebi-a-GCST90013534) rs141954310 -62.5658171684798 27.8668042074571 0.0247569808766833
Snackpot Rheumatoid arthritis (ebi-a-GCST90013534) rs150981940 -28.1509775564951 12.5360780229795 0.0247298412286492
Snackpot Rheumatoid arthritis (ebi-a-GCST90013534) rs76868724 23.1347878721622 9.56580874491766 0.0155851855279881
Snackpot Rheumatoid arthritis (ebi-a-GCST90013534) rs79505368 34.9439266750391 14.7913132247854 0.0181539652265909
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) rs11663173 130.665589851675 56.650974057951 0.0210825936934924
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) rs117983125 114.207778748069 44.1069217998791 0.0096160339619707
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) rs140930672 -70.162663329983 34.0403273778999 0.0392874920236765
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) rs187579178 84.398127251091 40.9018527612722 0.0390717521705643
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) rs187693471 83.3001118187564 31.8537605133939 0.0089206724366116
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) rs73035011 93.9516129032258 38.0040322580645 0.0134303699245328
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) All - MR Egger 21.7700938747386 9.72836153384336 0.0271776063576524
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) rs11663173 129.267043551914 56.3062619418126 0.0216882059849171
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) rs117983125 116.199007744201 44.382814974042 0.0088418787825608
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) rs140930672 -70.0293327316363 34.0403273778999 0.0396625535459368
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) rs187579178 84.4907851699677 40.915089606826 0.0389203984401077
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) rs187693471 82.4055617677087 31.7370800719529 0.0094176889970495
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) rs73035011 93.5931899641577 37.959229390681 0.0136774794949662
Snackpot Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) All - MR Egger 21.7602007756138 9.72544235650291 0.027200839606012
Snackpot Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) rs111624017 65.5053464539982 31.8078845762203 0.039455367153403
Snackpot Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) rs12561800 -90.0676839992183 43.9235401751612 0.0403101935660957
Snackpot Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) rs138628484 -130.589403375756 60.1317808466468 0.029876773632569
Snackpot Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) rs141355349 61.2588875757987 28.9439525737645 0.0343052055430173
Snackpot Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) rs59914248 39.0241559044653 13.9955323186306 0.005298062400293
Snackpot Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) All - MR Egger 17.5726182506968 7.59550769268136 0.0224848265067266
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs116374832 -104.609884438178 42.7377325713135 0.0143764433149664
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs116676851 70.3614935956681 31.9824970889401 0.0278068950269972
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs117522648 128.286336713357 53.7537511264315 0.0170070174767047
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs117769198 84.0220128719336 42.1353729440662 0.0461414755489566
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs12561800 -82.5620436659502 31.1772752304987 0.0080934049142647
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs142131091 21.019253408271 10.1298750617096 0.0379887063304031
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs145419059 261.718887365053 81.3552765762915 0.0012954435613213
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs150981940 53.9468406507476 25.2316169210068 0.0325114564607484
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs192501286 -121.765823709984 58.446620864396 0.0372176864013832
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs35346248 -57.2448573197123 26.2472229286527 0.0291843630230157
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs55871450 -35.9074909640689 15.5914105501878 0.0212771381759598
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs7340729 226.709896476892 81.3154807023373 0.0053029840525603
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) rs80061971 52.8528787096034 25.5295333218529 0.0384276107597864
Snackpot Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) All - MR Egger 13.9985596817188 6.23567698164451 0.0267028859837298
Snackpot Chondromalacia (finn-b-M13_CHONDROMALACIA) rs114880853 145.147055159291 55.079294512922 0.0084078283102817
Snackpot Chondromalacia (finn-b-M13_CHONDROMALACIA) rs11663173 -99.2770894478697 42.6064175547107 0.0198010203422768
Snackpot Chondromalacia (finn-b-M13_CHONDROMALACIA) rs117729114 58.7862865958825 28.3524848449564 0.0381342670071715
Snackpot Chondromalacia (finn-b-M13_CHONDROMALACIA) rs117983125 72.5599048048596 33.4910322723042 0.0302693911853277
Snackpot Chondromalacia (finn-b-M13_CHONDROMALACIA) rs187707703 -83.6786555212215 33.9412833361691 0.0136862447245267
Snackpot Chondromalacia (finn-b-M13_CHONDROMALACIA) rs72919932 95.218596260096 38.8707887506157 0.0143007715712302
Snackpot Chondromalacia (finn-b-M13_CHONDROMALACIA) rs73035011 60.8982974910394 30.2195340501792 0.0438840702123159
Snackpot Chondromalacia (finn-b-M13_CHONDROMALACIA) rs8015208 138.386229781784 48.6838147540824 0.0044754060147208
Snackpot Chondromalacia (finn-b-M13_CHONDROMALACIA) All - MR Egger -18.5015656790408 7.94384066911019 0.021618279137171
Snackpot Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) rs116412151 -71.6140270934792 22.9734476309819 0.0018254541968322
Snackpot Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) rs12561800 64.5307420369153 32.5096374198362 0.047147511415575
Snackpot Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) rs2695967 65.6626102275882 24.3673582719761 0.0070452986648808
Snackpot Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) rs59914248 -22.8588356806008 10.2964843030657 0.0264145451050738
Snackpot Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) rs62194265 229.721387377142 100.861018601251 0.0227502245590887
Snackpot Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) All - MR Egger -13.9514293378845 5.63632278022026 0.0147843258526636
Snackpot Gluteal tendinitis (finn-b-M13_GLUTEALTEND) rs111624017 -87.8443492190797 34.8522035620632 0.0117194256169572
Snackpot Gluteal tendinitis (finn-b-M13_GLUTEALTEND) rs114791547 358.619940528724 102.336759494358 0.0004577885682441
Snackpot Gluteal tendinitis (finn-b-M13_GLUTEALTEND) rs114993579 167.3206252862 66.4703294335252 0.011828402243786
Snackpot Gluteal tendinitis (finn-b-M13_GLUTEALTEND) rs1468798 -64.1374062398087 27.071666275086 0.0178280093539164
Snackpot Gluteal tendinitis (finn-b-M13_GLUTEALTEND) rs62194265 377.20737551783 163.691008041589 0.0212009480944311
Snackpot Gluteal tendinitis (finn-b-M13_GLUTEALTEND) rs8015208 -105.687783200567 53.7292723867925 0.0491782664219222
Snackpot Gluteal tendinitis (finn-b-M13_GLUTEALTEND) All - MR Egger 18.0342292065053 8.67704522323596 0.0399183556717264
Snackpot Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs113246204 -92.7364771534339 37.9682579148019 0.0145869862825177
Snackpot Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs114993579 89.1149560485935 45.1006976556257 0.0481648796189932
Snackpot Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs145135330 120.9249335415 53.8672517827756 0.0247765317645029
Snackpot Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs145710369 58.871498336623 26.6881654666259 0.0273908076999423
Snackpot Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs150427208 49.6772618097394 23.8363383885323 0.0371512667446953
Snackpot Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs192501286 173.342103980899 66.5472884081275 0.0091929003453181
Snackpot Osteonecrosis (finn-b-M13_OSTEONECROSIS) All - MR Egger 15.0223932599195 6.42232252028968 0.0210722492145154
Snackpot Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) rs111393448 17.9794236900251 6.19277102292854 0.0036926195451134
Snackpot Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) rs144939326 -8.97714035331459 4.45294660382668 0.0437999757901902
Snackpot Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) rs1468798 6.64518233047772 3.34889135915895 0.0472231645041677
Snackpot Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) rs7093445 7.59060285818694 2.44027458607302 0.0018673753039492
Snackpot Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) rs72919932 10.6078679224008 5.19266261935706 0.0410665819027064
Snackpot Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) rs76717272 16.2274338748883 6.06246937540232 0.0074350366843835
Snackpot Injuries to the knee and lower leg (finn-b-ST19_INJURI_KNEE_LOWER_LEG) All - MR Egger 2.71351952963188 1.03289435015275 0.0097959134210509
Snackpot Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs111624017 -15.8304587263829 5.58475069127036 0.0045885038918955
Snackpot Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs117541068 -14.9407936782623 7.00778052111158 0.0330044346643981
Snackpot Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs141510253 -24.0875573899736 12.1689931827668 0.047768656246682
Snackpot Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs145845264 11.0257846351414 4.95633039390524 0.0261090239577294
Snackpot Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs184560749 -12.0892481035634 5.46242230175174 0.0268861932821194
Snackpot Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs190398287 -34.3866262233609 14.5870758115656 0.0184066269497635
Snackpot Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs75293558 16.9385997507056 4.57329765829761 0.0002123900916398
Snackpot Rheumatoid arthritis (ieu-a-831) rs59914248 13.2520396806969 4.48048391874905 0.0030991839002709
Snackpot Rheumatoid arthritis (ieu-a-831) All - Inverse variance weighted 3.30444593690862 1.54400314273672 0.0323401552857712
Snackpot Psoriatic arthritis (ieu-b-5116) rs111393448 -32.3637271816776 9.8623064121939 0.0010323541381686
Snackpot Psoriatic arthritis (ieu-b-5116) rs117362095 -26.6387973017938 9.23306815088176 0.0039122576396035
Snackpot Psoriatic arthritis (ieu-b-5116) rs117972079 -24.0359273565003 12.0305623548413 0.0457269003147585
Snackpot Psoriatic arthritis (ieu-b-5116) rs144939326 -25.2961803217759 11.2473119045668 0.0245069765632441
Snackpot Psoriatic arthritis (ieu-b-5116) rs147606020 -24.6942596109644 10.7400747605039 0.0214899931379246
Snackpot Psoriatic arthritis (ieu-b-5116) rs1800493 -25.9898195431037 10.9223624536479 0.0173358928741346
Snackpot Psoriatic arthritis (ieu-b-5116) rs74324714 -30.4614729787046 11.1608688419188 0.0063466975284611
Snackpot Psoriatic arthritis (ieu-b-5116) rs859544 26.7595117133208 12.3467450511885 0.0302094490147005
Snackpot Psoriatic arthritis (ieu-b-5116) All - Inverse variance weighted -4.28825172927039 1.45953400217038 0.0033023422652591
Snackpot Psoriatic arthritis (ieu-b-5116) All - MR Egger -9.6489626261325 3.94220731145019 0.0163442799341047
Snackpot Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) rs116458593 5.69863977743812 2.28776532770331 0.012741290412323
Snackpot Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) rs118110367 5.61479277435662 2.34906645407389 0.0168381433703675
Snackpot Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) rs141355349 4.6076680163512 2.16795500190506 0.0335572324168204
Snackpot Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) rs187707703 4.73795946146204 2.22766565860031 0.0334307293415972
Snackpot Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) rs35346248 -4.68534042216283 2.36141994117167 0.0472424693112335
Snackpot Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) rs617799 -4.6434301294221 2.23413092179959 0.0376720210605929
Snackpot Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) rs77200066 2.21658041659711 0.862617550498025 0.0101816560441521
Snackpot Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) rs79070505 4.71051144787595 2.37794647204322 0.0476007305820363
Snackpot Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) All - MR Egger 1.16770395028805 0.508506053656594 0.0234207192938746
Snackpot Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs117765683 -1.52444578745916 0.53958316910599 0.0047246898472561
Snackpot Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs140930672 1.16926832270107 0.563277676355357 0.0379097384751634
Snackpot Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs148403887 -1.1200390399604 0.566752398015679 0.0481275454136986
Snackpot Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs190398287 -0.989840091880908 0.486016628873772 0.041686299446877
Snackpot Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs41303053 -1.22133654378283 0.499673776906123 0.0145146463924954
Snackpot Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs7340729 1.18673486870113 0.597202176373472 0.0469049301626815
Snackpot Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs73422081 -1.12196898219868 0.537827502583983 0.0369683821148734
Snackpot Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs78070167 1.20146607824071 0.554497344603186 0.0302526895057586
Snackpot Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs80025170 -1.4447934201371 0.584040018569997 0.0133687572907496
Snackpot Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs859544 -1.12150980890816 0.553894287353399 0.0428907508843675
Snackpot Pain type(s) experienced in last month: Knee pain (ukb-a-476) All - Inverse variance weighted -0.103962680820049 0.0485561658375751 0.0322675120590308
Snackpot Operative procedures - secondary OPCS: Y81.1 Epidural anaesthetic using lumbar approach (ukb-b-13920) All - Inverse variance weighted -0.140723710265543 0.071216081019781 0.0481536096228981
Snackpot Operation code: knee surgery (not replacement) (ukb-b-1508) rs12561800 -0.459349629603311 0.207547831802597 0.0268822769365533
Snackpot Operation code: knee surgery (not replacement) (ukb-b-1508) rs76517621 0.613983879240496 0.211648277041174 0.0037201747356632
Snackpot Operation code: knee surgery (not replacement) (ukb-b-1508) All - MR Egger 0.200164692281479 0.085936315015433 0.0278863938350774
Snackpot Ankle spacing width (ukb-b-4080) rs111624017 -2.44794739416792 1.19085570557866 0.0398191107891846
Snackpot Ankle spacing width (ukb-b-4080) rs116374832 4.09993747744572 1.26412002651963 0.0011814815476829
Snackpot Ankle spacing width (ukb-b-4080) rs144101715 -2.7534391011384 1.22170052224913 0.0242102744659746
Snackpot Ankle spacing width (ukb-b-4080) rs35346248 -4.81063132488496 1.29408885668632 0.0002012925993666
Snackpot Ankle spacing width (ukb-b-4080) rs7340729 2.94815018638313 1.31004236452179 0.0244220715672453
Snackpot Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) rs114880853 -0.162489164460216 0.0734502063506427 0.0269503872817511
Snackpot Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) rs117419380 0.202765158026571 0.0869778901958858 0.0197414222369606
Snackpot Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) rs145419059 0.141527763125505 0.0687183071350705 0.0394430095368032
Snackpot Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) rs1468798 -0.212135610813237 0.0747726786572173 0.0045529080720286
Snackpot Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) rs147606020 0.175985437353877 0.0758644106232384 0.0203551396252625
Snackpot Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) rs74776989 -0.161947459333869 0.0808855869543712 0.0452654359151691
Snackpot Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) rs859544 0.197790408147574 0.0835637948675487 0.0179358869421349
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs112869543 0.58595975112357 0.25231640881254 0.0202156456066633
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs117488292 0.675952510148432 0.327547067429545 0.0390480152858047
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs117983125 -0.782636962967939 0.331257737004232 0.0181461460885672
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs145469972 0.894345406084912 0.353178209732568 0.0113324108587149
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs148403887 -0.742244090660586 0.352805334282818 0.0353928721962444
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs17083751 -0.68560863524634 0.340957571871326 0.0443431307716796
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs212288 0.833828650838831 0.320262532230519 0.0092256131485527
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs62072033 0.659299452197209 0.306051421488264 0.0312235995516627
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs72919932 -0.814071522251301 0.344371450444195 0.0180820134768394
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs75293558 0.853407168892628 0.34627568285672 0.013719267992571
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs80037115 -1.03084423613646 0.338714273938081 0.0023391838388078
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) rs859544 -0.763557111680201 0.345695258485578 0.0271914890950403
Snackpot Other joint disorders (ukb-d-M13_OTHERJOINT) All - MR Egger 0.166832323666322 0.08176972023085 0.0435365896959056
Snackpot Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) rs113278375 0.1327776272113 0.0607484775412726 0.0288379467239912
Snackpot Diagnoses - main ICD10: M84 Disorders of continuity of bone (ukb-d-M84) All - Inverse variance weighted -0.015380255278174 0.0076359643726789 0.0439899713011903
Snackpot Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) rs11024072 -0.311352201489514 0.144480069834769 0.0311631065093046
Snackpot Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) rs116412151 -0.301584645762728 0.128831676776882 0.0192362897084317
Snackpot Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) rs117541068 -0.416442069299924 0.14629058815668 0.0044178146253973
Snackpot Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) rs144027086 0.272171165357485 0.1365458362076 0.0462331348190169
Snackpot Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) rs145419059 -0.244979252382459 0.120608713999367 0.0422356919651259
Snackpot Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) rs1729766 0.298355097873375 0.148644685762719 0.0447316049273366
Snackpot Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) rs187707703 -0.292978479338299 0.144313023814882 0.0423403128433092
Snackpot Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) rs35346248 0.444376040652006 0.150829402647755 0.0032168738954979
Snackpot Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) All - MR Egger -0.0684336635440162 0.0307383320544964 0.0278745688680075
Snackpot Fractured/broken bones in last 5 years (ukb-e-2463_CSA) rs1800493 -101.124420853885 34.2658617340512 0.0031657149899918
Snackpot Fractured/broken bones in last 5 years (ukb-e-2463_CSA) rs77200066 -41.3072913768479 15.7197707417506 0.0085957061512886
Snackpot Fractured/broken bones in last 5 years (ukb-e-2463_CSA) All - Inverse variance weighted -7.73461347241198 3.3980732751319 0.0228354665397173
Snackpot Fractured/broken bones in last 5 years (ukb-e-2463_CSA) All - MR Egger -19.4286418909832 8.10454745763064 0.0205458488689081
Snackpot Heel bone mineral density (BMD) (ukb-e-3148_CSA) rs1729766 -27.215360764462 10.4105013384164 0.0089430928223452
Snackpot Heel bone mineral density (BMD) (ukb-e-3148_CSA) rs41303053 -18.4762662990184 7.92450265541715 0.0197250936431408
Snackpot Neck/shoulder pain for 3+ months (ukb-e-3404_CSA) rs112869543 48.7220024203111 22.6445769141442 0.031429113268123
Snackpot Neck/shoulder pain for 3+ months (ukb-e-3404_CSA) rs11663173 101.3453621447 40.2426773297615 0.0117904298268739
Snackpot Neck/shoulder pain for 3+ months (ukb-e-3404_CSA) rs117488292 -138.111395778527 54.0562817245808 0.0106201365965008
Snackpot Neck/shoulder pain for 3+ months (ukb-e-3404_CSA) rs77707295 -30.3256756974472 13.1613680386959 0.0212146105524946
Snackpot Neck/shoulder pain for 3+ months (ukb-e-3404_CSA) All - Inverse variance weighted -7.92522070168596 3.2365433170517 0.0143385464893934
Snackpot Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs77707295 -15.4788593976753 7.06896829498319 0.0285466219742704
Snackpot Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) All - Inverse variance weighted 3.92011125087912 1.81069060765701 0.0303891196863195
Snackpot Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs77707295 -15.1938203535228 7.02187488768842 0.0304809326089632
Snackpot Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) All - Inverse variance weighted 3.76679711865758 1.79848700676085 0.0362220896944197
Snackpot M75 Shoulder lesions (ukb-e-M75_CSA) rs76517621 -112.196125170041 43.0399004903625 0.0091394507253962