ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Mixed vegetable | Frozen shoulder (ebi-a-GCST90000513) | All - MR Egger | 0.719457052580928 | 0.284543146090944 | 0.0299496657928689 |
| Mixed vegetable | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs11134553 | 0.879730746089049 | 0.29236198856799 | 0.0026206921553682 |
| Mixed vegetable | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | All - Inverse variance weighted | 0.221662196720696 | 0.0980454006469952 | 0.0237709148499567 |
| Mixed vegetable | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs11134553 | 0.881223676293622 | 0.293158844765343 | 0.0026474407315725 |
| Mixed vegetable | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | All - Inverse variance weighted | 0.221492993974249 | 0.098052130864095 | 0.0238876798745674 |
| Mixed vegetable | Neck circumference (ebi-a-GCST90017134) | rs2730078 | -5.91376180166427 | 2.61090086780353 | 0.0235110029084736 |
| Mixed vegetable | Neck circumference (ebi-a-GCST90017134) | rs80030163 | 7.6303185675391 | 3.85738985273952 | 0.0479169675239884 |
| Mixed vegetable | Neck circumference (ebi-a-GCST90017134) | All - Inverse variance weighted | -1.90584204432153 | 0.910298674431173 | 0.0362916376847065 |
| Mixed vegetable | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | rs2730078 | -5.91376180166427 | 2.61090086780353 | 0.0235110029084736 |
| Mixed vegetable | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | rs80030163 | 7.6303185675391 | 3.85738985273952 | 0.0479169675239884 |
| Mixed vegetable | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | All - Inverse variance weighted | -1.90584204432153 | 0.910298674431173 | 0.0362916376847065 |
| Mixed vegetable | Achilles tendon injury (ebi-a-GCST90018567) | All - Inverse variance weighted | -4.55412223721552 | 1.99438157133232 | 0.0224023513604096 |
| Mixed vegetable | Rheumatoid arthritis (ebi-a-GCST90018910) | rs12856231 | 1.37048064653339 | 0.672905146746065 | 0.0416838796499597 |
| Mixed vegetable | Rheumatoid arthritis (ebi-a-GCST90018910) | rs12980103 | 1.19978552506543 | 0.599892762532715 | 0.0455002638963584 |
| Mixed vegetable | Rheumatoid arthritis (ebi-a-GCST90018910) | All - Inverse variance weighted | 0.403629305741028 | 0.160015048494441 | 0.0116541869455901 |
| Mixed vegetable | Rheumatoid arthritis (ebi-a-GCST90038685) | All - Inverse variance weighted | 0.0070507990902989 | 0.0023408174903921 | 0.0025943881533571 |
| Mixed vegetable | Fractures (ebi-a-GCST90038703) | rs2730078 | 0.0264526702881621 | 0.0111459072702175 | 0.017629558699099 |
| Mixed vegetable | Fractures (ebi-a-GCST90038703) | rs72769311 | 0.0260488228778449 | 0.0101472152355774 | 0.0102555753631726 |
| Mixed vegetable | Fractures (ebi-a-GCST90038703) | All - Inverse variance weighted | 0.0062006050550429 | 0.0030008165054438 | 0.0387995982338036 |
| Mixed vegetable | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | rs59455016 | -5.74563772445189 | 2.82046053284245 | 0.0416372663768104 |
| Mixed vegetable | Benign neoplasm: Skin of scalp and neck (finn-b-CD2_BENIGN_SKIN_SCALPNECK) | All - Inverse variance weighted | -1.82424242040365 | 0.775911849275907 | 0.0187182573442676 |
| Mixed vegetable | Cervical root disorders (finn-b-G6_CERVROOT) | rs12980103 | -10.2034857485653 | 4.22313887252013 | 0.0156881611701885 |
| Mixed vegetable | Cervical root disorders (finn-b-G6_CERVROOT) | rs80030163 | 5.96096901766728 | 2.81802102585504 | 0.0344041101682328 |
| Mixed vegetable | Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) | rs12980103 | 1.81029585861642 | 0.913111107571921 | 0.0474168071151743 |
| Mixed vegetable | Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) | All - MR Egger | -1.95807260371502 | 0.539312043616933 | 0.0039519056478991 |
| Mixed vegetable | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | rs59455016 | 8.65014715446258 | 4.16524288753431 | 0.0378251050256002 |
| Mixed vegetable | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | All - Inverse variance weighted | 1.78923472294127 | 0.703113097322123 | 0.01093614923147 |
| Mixed vegetable | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | rs59455016 | 5.88617850332338 | 2.90864298233044 | 0.0430025258670679 |
| Mixed vegetable | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | rs7618279 | 3.97941776895327 | 1.4532472011708 | 0.0061758879719791 |
| Mixed vegetable | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | All - Inverse variance weighted | 1.15915735911775 | 0.488567822646822 | 0.0176652070302049 |
| Mixed vegetable | Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) | rs7618279 | 4.21059500172451 | 1.71052508925492 | 0.0138326397735575 |
| Mixed vegetable | Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) | All - MR Egger | 2.9318758529855 | 1.16066334655795 | 0.0281714617171944 |
| Mixed vegetable | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | rs12980103 | 3.99486109562715 | 1.91381717604464 | 0.036853921160406 |
| Mixed vegetable | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | rs2730078 | 6.02789954451907 | 2.32555651066653 | 0.0095412965423648 |
| Mixed vegetable | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | All - MR Egger | -2.93900147947737 | 1.18706100324298 | 0.0307991119488563 |
| Mixed vegetable | Dislocation, sprain and strain of joints and ligaments of elbow (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ELBOW) | rs2730078 | 5.80319086327369 | 2.04021215352953 | 0.0044494368975539 |
| Mixed vegetable | Dislocation, sprain and strain of joints and ligaments of elbow (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ELBOW) | All - MR Egger | -2.78856914009033 | 1.10330824038793 | 0.0281000357416798 |
| Mixed vegetable | Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) | rs11134553 | 2.91064981949458 | 1.18832731648616 | 0.0143107515227529 |
| Mixed vegetable | Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) | rs2730078 | 2.53599797405506 | 1.28404960711649 | 0.0482681480094495 |
| Mixed vegetable | Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) | All - Inverse variance weighted | 0.797247045034574 | 0.340166752289135 | 0.0190937890023533 |
| Mixed vegetable | Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) | rs116940027 | -4.05632454142845 | 2.01855713063434 | 0.0444823508706789 |
| Mixed vegetable | Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) | All - MR Egger | -1.79171132880307 | 0.799342284115036 | 0.0465801600531055 |
| Mixed vegetable | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | rs12980103 | -10.0628029325731 | 4.3744392595306 | 0.021427602193693 |
| Mixed vegetable | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | All - Inverse variance weighted | -3.99780341273516 | 1.25976396524853 | 0.0015063659763771 |
| Mixed vegetable | Traumatic amputation of wrist and hand (finn-b-ST19_TRAUMAT_AMPUT_WRIST_HAND) | All - Inverse variance weighted | -1.36752905085425 | 0.569282479599301 | 0.0162968991068893 |
| Mixed vegetable | Osteocrin (prot-a-2157) | rs80030163 | -1.9903018740436 | 0.998628748584034 | 0.0462576337254643 |
| Mixed vegetable | Osteocrin (prot-a-2157) | All - MR Egger | -1.28733709429337 | 0.580771140048251 | 0.0486538996768147 |
| Mixed vegetable | Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) | All - Inverse variance weighted | 0.0063817726298154 | 0.0027756542708153 | 0.0214938236515414 |
| Mixed vegetable | Fracture resulting from simple fall (ukb-a-332) | rs12980103 | 0.307030955528304 | 0.149778889083544 | 0.0403747045063337 |
| Mixed vegetable | Fracture resulting from simple fall (ukb-a-332) | All - Inverse variance weighted | 0.0927643533051349 | 0.0410431510408944 | 0.0238109217656715 |
| Mixed vegetable | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | rs72769311 | 0.0095701652927965 | 0.0047150611662903 | 0.0423869211743818 |
| Mixed vegetable | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | rs73555777 | 0.0125868625253827 | 0.0046169188735183 | 0.0064058986687641 |
| Mixed vegetable | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | rs7618279 | 0.0100038218816708 | 0.0047785079746823 | 0.0363042559960204 |
| Mixed vegetable | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | All - Inverse variance weighted | 0.0036133673546302 | 0.0013218375400845 | 0.0062647211807993 |
| Mixed vegetable | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | rs11134553 | 0.0272238643200963 | 0.0120236913357401 | 0.0235627246875111 |
| Mixed vegetable | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | rs62542879 | 0.0228005229542228 | 0.011118744035151 | 0.0403021785067682 |
| Mixed vegetable | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | All - Inverse variance weighted | 0.0076085281526912 | 0.0037222011577149 | 0.040944285682738 |
| Mixed vegetable | Operative procedures - main OPCS: S06.5 Excision of lesion of skin of head or neck NEC (ukb-b-10810) | rs116940027 | -0.025298609027945 | 0.0120484217277135 | 0.0357513098327674 |
| Mixed vegetable | Operative procedures - main OPCS: S06.5 Excision of lesion of skin of head or neck NEC (ukb-b-10810) | All - MR Egger | -0.0371984054120817 | 0.0135569615987006 | 0.0406053180857393 |
| Mixed vegetable | Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC (ukb-b-13151) | All - Inverse variance weighted | 0.0065476634462869 | 0.0030865080667619 | 0.0338896472399115 |
| Mixed vegetable | Fractured/broken bones in last 5 years (ukb-b-13346) | rs11134553 | 0.0781727587244284 | 0.0245742704572804 | 0.0014672631284486 |
| Mixed vegetable | Fractured/broken bones in last 5 years (ukb-b-13346) | rs936730 | 0.0480057815190499 | 0.0241713586201048 | 0.0470266022783282 |
| Mixed vegetable | Fractured/broken bones in last 5 years (ukb-b-13346) | All - Inverse variance weighted | 0.016690634804212 | 0.0082205678505048 | 0.042320915028744 |
| Mixed vegetable | Diagnoses - secondary ICD10: M13.99 Arthritis, unspecified (Site unspecified) (ukb-b-15026) | All - Inverse variance weighted | 0.0079394438991886 | 0.0032013500978471 | 0.0131371373326918 |
| Mixed vegetable | Operative procedures - main OPCS: W87.9 Unspecified diagnostic endoscopic examination of knee joint (ukb-b-15942) | All - Inverse variance weighted | 0.0070884087161048 | 0.0032482955509488 | 0.0290952712069464 |
| Mixed vegetable | Fractured heel (right) (ukb-b-3499) | rs62542879 | 0.031808674979577 | 0.0153444422055922 | 0.0381744249086793 |
| Mixed vegetable | Fractured heel (right) (ukb-b-3499) | rs7618279 | 0.0432613700979707 | 0.0164975717068896 | 0.0087341809371268 |
| Mixed vegetable | Fractured heel (right) (ukb-b-3499) | All - Inverse variance weighted | 0.0126278344762487 | 0.0045148759430117 | 0.0051589206202849 |
| Mixed vegetable | Diagnoses - main ICD10: M75.0 Adhesive capsulitis of shoulder (ukb-b-4921) | All - Inverse variance weighted | 0.0063067799958938 | 0.0028108615434524 | 0.0248505659925083 |
| Mixed vegetable | Non-cancer illness code, self-reported: spine arthritis/spondylitis (ukb-b-5389) | All - Inverse variance weighted | 0.0085612398110323 | 0.0038478066167371 | 0.0260835047487144 |
| Mixed vegetable | Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) | rs2730078 | 0.0119624558162097 | 0.0056603760125266 | 0.0345693085961127 |
| Mixed vegetable | Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) | All - Inverse variance weighted | 0.0070102432453228 | 0.0032187384212544 | 0.0294099467904814 |
| Mixed vegetable | Operation code: reduction or fixation of bone fracture (ukb-b-847) | rs11134553 | 0.0363479993983153 | 0.0173132897111913 | 0.0357792180607917 |
| Mixed vegetable | Operation code: reduction or fixation of bone fracture (ukb-b-847) | rs80030163 | 0.034873606391224 | 0.0171080506369363 | 0.0415066990534151 |
| Mixed vegetable | Operation code: reduction or fixation of bone fracture (ukb-b-847) | All - Inverse variance weighted | 0.0158010061301338 | 0.0048762989007959 | 0.0011937525215624 |
| Mixed vegetable | Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) | All - Inverse variance weighted | 0.0115173078889191 | 0.0038684924014178 | 0.0029088625382555 |
| Mixed vegetable | Adhesive capsulitis of shoulder (ukb-d-M13_ADHCAPSULITIS) | rs59455016 | 0.0113679302476825 | 0.0053577313962588 | 0.0338561710294323 |
| Mixed vegetable | Adhesive capsulitis of shoulder (ukb-d-M13_ADHCAPSULITIS) | rs936730 | 0.0109389437666154 | 0.0053076778425494 | 0.0393062803883994 |
| Mixed vegetable | Adhesive capsulitis of shoulder (ukb-d-M13_ADHCAPSULITIS) | All - Inverse variance weighted | 0.0033042096417816 | 0.001681521876851 | 0.0494129191893781 |