ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Celery | Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) | rs143043085 | -2.6648336954705 | 1.04520307538024 | 0.0107851331199817 |
| Celery | Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) | All - Inverse variance weighted | -0.56831965151751 | 0.281625432010158 | 0.0435914352383152 |
| Celery | Rheumatoid arthritis (ebi-a-GCST90013534) | All - MR Egger | 0.701069766994935 | 0.284704776284622 | 0.0315416141042054 |
| Celery | Arthritis (not osteoarthritis) (ebi-a-GCST90038699) | All - Inverse variance weighted | 0.0056531344305569 | 0.00268841189404 | 0.0354851460176039 |
| Celery | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | rs2173148 | -2.73067779123492 | 1.26721392365316 | 0.0311722233151045 |
| Celery | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | rs9409285 | -3.20565977294569 | 1.33360899129633 | 0.0162279613381108 |
| Celery | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | All - Inverse variance weighted | -0.73971497226317 | 0.286953863615782 | 0.0099426212282973 |
| Celery | Osteopathies and chondropathies (finn-b-M13_OSTEOCHONDRO) | rs139795526 | -2.55576247193615 | 0.858077939000902 | 0.0028968800175528 |
| Celery | Osteopathies and chondropathies (finn-b-M13_OSTEOCHONDRO) | rs3110454 | 1.6984482359299 | 0.860253002613846 | 0.0483409394676693 |
| Celery | Osteopathies and chondropathies (finn-b-M13_OSTEOCHONDRO) | All - MR Egger | -0.968382519015346 | 0.336085362419646 | 0.0128598273111855 |
| Celery | Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) | rs116191942 | -1.70504546787914 | 0.722876419561664 | 0.0183392895271589 |
| Celery | Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) | rs3110454 | -2.40429685345921 | 1.09185958024065 | 0.0276638814794126 |
| Celery | Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) | All - Inverse variance weighted | -0.688344913269518 | 0.242986975668478 | 0.0046135469278489 |
| Celery | Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) | rs116191942 | -1.7364748774253 | 0.705852156057495 | 0.0138893927920906 |
| Celery | Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) | rs3110454 | -2.65244675805936 | 1.06428736861841 | 0.0126944526869709 |
| Celery | Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) | All - Inverse variance weighted | -0.713505633533686 | 0.236754675716717 | 0.0025808981386934 |
| Celery | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | rs12551354 | -1.21367801329184 | 0.480126884519571 | 0.0114770678060073 |
| Celery | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | rs61990752 | 1.76001698763496 | 0.812629653223567 | 0.0303242452740913 |
| Celery | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | All - MR Egger | -0.685574685065907 | 0.301648695428269 | 0.0406604061688115 |
| Celery | Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) | rs116191942 | -7.45924653228848 | 3.42056740560701 | 0.0292052843601424 |
| Celery | Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) | rs117343799 | -10.2842142746848 | 4.96012050508775 | 0.0381369358372378 |
| Celery | Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) | rs143043085 | 21.7524653184021 | 9.17934146749123 | 0.0178015804887006 |
| Celery | Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) | All - Inverse variance weighted | -3.74477990706618 | 1.36832716042565 | 0.0062047973617736 |
| Celery | Other/unspecified rheumatoid arthritis (finn-b-RHEUMA_NOS) | rs59063355 | -3.96544902486408 | 1.89381309931849 | 0.0362691820983476 |
| Celery | Other/unspecified rheumatoid arthritis (finn-b-RHEUMA_NOS) | All - Inverse variance weighted | -1.12319064699402 | 0.412159981846208 | 0.0064275646564045 |
| Celery | Other (seronegative) rheumatoid arthritis, wide (finn-b-RHEUMA_OTHER_WIDE) | rs116191942 | -2.46458953191133 | 0.992645518166199 | 0.0130336102648296 |
| Celery | Other (seronegative) rheumatoid arthritis, wide (finn-b-RHEUMA_OTHER_WIDE) | rs3110454 | -3.09911658633962 | 1.49441386992533 | 0.0380978206130131 |
| Celery | Other (seronegative) rheumatoid arthritis, wide (finn-b-RHEUMA_OTHER_WIDE) | All - Inverse variance weighted | -0.904319570412152 | 0.331853764322317 | 0.0064290887498956 |
| Celery | Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) | rs3110454 | -2.79030781617055 | 1.25177840764963 | 0.0258089223271646 |
| Celery | Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) | rs73169197 | -3.07068899260834 | 1.36575297732345 | 0.0245539607394137 |
| Celery | Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) | All - Inverse variance weighted | -0.628272606280829 | 0.284052615691463 | 0.0269792628431877 |
| Celery | Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) | rs3110454 | -2.82890891244168 | 1.24626396532519 | 0.0232129529564645 |
| Celery | Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) | rs73169197 | -2.87583916229006 | 1.35673215184575 | 0.0340329689383513 |
| Celery | Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) | All - Inverse variance weighted | -0.648938016038988 | 0.281153591731365 | 0.0209921094971917 |
| Celery | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | rs61990752 | -2.74007285081916 | 1.12298067656523 | 0.0146872619106967 |
| Celery | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | rs9409285 | -3.27381696159797 | 1.22228558316427 | 0.0073966278267921 |
| Celery | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | All - Inverse variance weighted | -0.693632781478156 | 0.292804595078193 | 0.0178397625988711 |
| Celery | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | rs144837581 | -6.28142899133295 | 2.7280165873577 | 0.0213034649592229 |
| Celery | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | All - Inverse variance weighted | -3.23462554124344 | 1.31790376088678 | 0.0141131061983515 |
| Celery | Sequelae of injuries of neck and trunk (finn-b-ST19_SEQUEL_INJURI_NECK_TRUNK) | All - Inverse variance weighted | -3.20873764674403 | 0.930188465735867 | 0.0005615082620175 |
| Celery | Sequelae of injuries of neck and trunk (finn-b-ST19_SEQUEL_INJURI_NECK_TRUNK) | All - MR Egger | -3.36880881239435 | 1.52888254675642 | 0.0462041979296021 |
| Celery | Knee osteoarthritis (ieu-a-1171) | rs3110454 | -3.41208324602133 | 1.49795414189763 | 0.0227367733165292 |
| Celery | Fractured/broken bones in last 5 years (ukb-a-308) | All - Inverse variance weighted | 0.0264154624851861 | 0.0102892008438843 | 0.0102493977480548 |
| Celery | Fractured bone site(s): Other bones (ukb-a-441) | All - Inverse variance weighted | 0.0159606760822446 | 0.0077468996979407 | 0.0393730933842581 |
| Celery | Non-cancer illness code self-reported: joint disorder (ukb-a-86) | rs117343799 | 0.0197925825084848 | 0.0095497445884581 | 0.0382116485617475 |
| Celery | Non-cancer illness code self-reported: joint disorder (ukb-a-86) | All - Inverse variance weighted | 0.0049000691646111 | 0.0024123112496288 | 0.0422270373980482 |
| Celery | Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) | rs3110454 | -0.025963373074081 | 0.0121085021671758 | 0.0320147304842074 |
| Celery | Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) | All - Inverse variance weighted | -0.010719312763414 | 0.0054015094546154 | 0.0471997724138904 |
| Celery | Fractured heel (ukb-b-18389) | rs3110454 | -0.0279891586063901 | 0.0082935006782764 | 0.0007386118184925 |
| Celery | Fractured heel (ukb-b-18389) | rs73169197 | -0.0204897225735333 | 0.0076792122293526 | 0.0076257414406259 |
| Celery | Fractured heel (ukb-b-18389) | All - Inverse variance weighted | -0.0057133004939467 | 0.0024930189813863 | 0.0219218279466895 |
| Celery | Operative procedures - main OPCS: W26.2 Manipulation of fracture of bone NEC (ukb-b-1935) | All - Inverse variance weighted | -0.0081207845547305 | 0.0039726120440209 | 0.0409345137149871 |
| Celery | Fractured heel (right) (ukb-b-3499) | All - Inverse variance weighted | 0.0121970087426596 | 0.0059080343251965 | 0.0389723879589961 |
| Celery | Fractured heel (right) (ukb-b-3499) | All - MR Egger | 0.0276477976696248 | 0.0108606517866296 | 0.0243908802594748 |
| Celery | Non-cancer illness code, self-reported: fracture wrist / colles fracture (ukb-b-7831) | rs2173148 | 0.0127920199165657 | 0.0055949232943076 | 0.0222330904980563 |
| Celery | Non-cancer illness code, self-reported: fracture wrist / colles fracture (ukb-b-7831) | All - Inverse variance weighted | 0.0093185957360045 | 0.0039495145392876 | 0.0183031254448732 |
| Celery | Operative procedures - main OPCS: W37.1 Primary total prosthetic replacement of hip joint using cement (ukb-b-898) | All - Inverse variance weighted | 0.0099160997384716 | 0.0045424221773065 | 0.0290359376780788 |
| Celery | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs144837581 | -0.0523468569022633 | 0.0236226058357629 | 0.0266939306877263 |
| Celery | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs3110454 | -0.0652943057868558 | 0.0234408465771857 | 0.0053446452107042 |
| Celery | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | All - Inverse variance weighted | -0.0165208951564944 | 0.0065655165525494 | 0.0118589787297061 |
| Celery | Ankle spacing width (ukb-e-3143_EAS) | rs12551354 | -0.948185947884252 | 0.436165536026756 | 0.0297116662879534 |
| Celery | Ankle spacing width (ukb-e-3143_EAS) | All - Inverse variance weighted | -0.803841060431004 | 0.385329377396084 | 0.0369682856990827 |
| Celery | Heel bone mineral density (BMD) (left) (ukb-e-4105_CSA) | rs79810016 | 1.28762404658411 | 0.635768315994675 | 0.0428361688456181 |
| Celery | Heel bone mineral density (BMD) (left) (ukb-e-4105_CSA) | All - Inverse variance weighted | 0.554447163064826 | 0.269926374132697 | 0.0399690979340229 |
| Celery | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_CSA) | rs2173148 | 2.28715291795631 | 1.07376755035213 | 0.033169457838093 |
| Celery | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_CSA) | rs79810016 | 1.40339034376597 | 0.638764991262326 | 0.0280178011793915 |
| Celery | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_CSA) | All - Inverse variance weighted | 0.622431571559641 | 0.271507212140793 | 0.0218765341786756 |
| Celery | Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) | rs2173148 | 2.24341721616651 | 1.08778540348988 | 0.0391724153431648 |
| Celery | Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) | rs79810016 | 1.61031865698478 | 0.650278533080141 | 0.0132732579701411 |
| Celery | Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) | All - Inverse variance weighted | 0.949547213135389 | 0.275182705984421 | 0.0005593285920134 |
| Celery | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA) | rs2173148 | 2.46658143811959 | 1.09339254474499 | 0.0240770551534949 |
| Celery | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA) | rs79810016 | 1.69233292746784 | 0.653117488596862 | 0.0095652575666418 |
| Celery | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA) | All - Inverse variance weighted | 0.986786524270142 | 0.276616547056389 | 0.0003606172148197 |
| Celery | Pain in joint (ukb-e-745_AFR) | All - Inverse variance weighted | -3.09755135891321 | 1.09443093147432 | 0.0046506568499058 |
| Celery | M75 Shoulder lesions (ukb-e-M75_CSA) | rs12551354 | -4.63231934902725 | 2.15238210169725 | 0.0313829740106176 |
| Celery | M75 Shoulder lesions (ukb-e-M75_CSA) | rs79810016 | -8.75502337406709 | 2.87049946690724 | 0.0022884136620453 |
| Celery | M75 Shoulder lesions (ukb-e-M75_CSA) | All - Inverse variance weighted | -3.30472248259786 | 1.4176853547262 | 0.0197497178734647 |