ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Mozzarella | Rheumatoid Arthritis (bbj-a-73) | All - Inverse variance weighted | 2.04411621140803 | 0.94078206331337 | 0.0297965783435147 |
| Mozzarella | Rheumatoid Arthritis (bbj-a-74) | All - Inverse variance weighted | 1.91598821616358 | 0.756166916499571 | 0.0112827795447208 |
| Mozzarella | Rheumatoid arthritis (ebi-a-GCST002318) | All - Inverse variance weighted | 1.81292799035421 | 0.799309233938095 | 0.0233219904497642 |
| Mozzarella | Total body bone mineral density (age 0-15) (ebi-a-GCST005345) | rs116735069 | -6.66221808914665 | 2.48102847326239 | 0.0072472392311813 |
| Mozzarella | Total body bone mineral density (age 0-15) (ebi-a-GCST005345) | rs7950374 | 4.62940279014444 | 2.21332761134643 | 0.0364740391656097 |
| Mozzarella | Total body bone mineral density (age 0-15) (ebi-a-GCST005345) | All - MR Egger | -2.0721128554826 | 0.91938932527331 | 0.0362129542323515 |
| Mozzarella | Total body bone mineral density (ebi-a-GCST005348) | rs116735069 | -2.67624530592252 | 1.25648652293975 | 0.0331762780015911 |
| Mozzarella | Total body bone mineral density (ebi-a-GCST005348) | rs7950374 | 2.06126693575774 | 0.963050945395011 | 0.0323264212100619 |
| Mozzarella | Total body bone mineral density (ebi-a-GCST005348) | All - MR Egger | -0.975173795710996 | 0.402634601580379 | 0.0250599750876836 |
| Mozzarella | Total body bone mineral density (age over 60) (ebi-a-GCST005349) | All - Inverse variance weighted | -0.844096682663367 | 0.404998395698758 | 0.0371421973517963 |
| Mozzarella | Total body bone mineral density (age over 60) (ebi-a-GCST005349) | All - MR Egger | -1.68934875018177 | 0.696761397450029 | 0.0249232059648873 |
| Mozzarella | Osteoarthritis (self-reported) (ebi-a-GCST005811) | rs116735069 | -5.83222710461493 | 2.5545968239996 | 0.0224284648445607 |
| Mozzarella | Osteoarthritis (self-reported) (ebi-a-GCST005811) | rs147986150 | -6.40330038499593 | 2.63163824097023 | 0.0149660596931708 |
| Mozzarella | Osteoarthritis (self-reported) (ebi-a-GCST005811) | rs1714348 | 4.84596442952343 | 2.38349777474274 | 0.0420392383110507 |
| Mozzarella | Osteoarthritis (self-reported) (ebi-a-GCST005811) | All - MR Egger | -1.81454627353982 | 0.867661778834475 | 0.0494697044031926 |
| Mozzarella | Osteoprotegerin levels (ebi-a-GCST90010243) | rs116968441 | -18.0571857872749 | 8.95550275976591 | 0.0437662160887972 |
| Mozzarella | Osteoprotegerin levels (ebi-a-GCST90010243) | rs352863 | -16.8703566591422 | 6.96541760722348 | 0.0154346479773603 |
| Mozzarella | Osteoprotegerin levels (ebi-a-GCST90010243) | All - Inverse variance weighted | -3.38641700102423 | 1.43822795626036 | 0.0185438521814866 |
| Mozzarella | Fractures (ebi-a-GCST90038703) | rs116735069 | 0.130551789251006 | 0.0474511780448502 | 0.0059361686723885 |
| Mozzarella | Fractures (ebi-a-GCST90038703) | All - Inverse variance weighted | 0.027171728971574 | 0.0103265918325639 | 0.0085074237960681 |
| Mozzarella | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | rs116735069 | 0.0948686368186045 | 0.0326973642178194 | 0.0037148104455114 |
| Mozzarella | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | rs12878562 | 0.0761570337227187 | 0.0327815840652845 | 0.0201702820586038 |
| Mozzarella | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | All - Inverse variance weighted | 0.0175956055467149 | 0.0074766726223641 | 0.0186025826714573 |
| Mozzarella | Pain in joint (finn-b-JOINTPAIN) | rs12162199 | 6.04652379374684 | 2.04021134497009 | 0.0030398894631724 |
| Mozzarella | Pain in joint (finn-b-JOINTPAIN) | rs150078925 | -3.38290438330158 | 1.69650130267064 | 0.0461468507860314 |
| Mozzarella | Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) | All - MR Egger | -6.24923911330903 | 2.92550206296716 | 0.0452171633841185 |
| Mozzarella | Peroneal tendinitis (finn-b-M13_PERONEALTEND) | rs73211188 | 61.9868410563946 | 30.9964864516841 | 0.0455216295336582 |
| Mozzarella | Peroneal tendinitis (finn-b-M13_PERONEALTEND) | rs75314632 | 55.927102905671 | 23.1521647521925 | 0.0157079411184939 |
| Mozzarella | Peroneal tendinitis (finn-b-M13_PERONEALTEND) | All - Inverse variance weighted | 11.4842558318306 | 4.31431316204111 | 0.0077701727747248 |
| Mozzarella | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | All - Inverse variance weighted | -4.99343207551544 | 1.94010251523784 | 0.0100588966375883 |
| Mozzarella | Drug-induced osteoporosis with pathological fracture (finn-b-OSTPOPATFRACTURE) | rs117549105 | 108.381803074366 | 46.1154964686332 | 0.018762054516912 |
| Mozzarella | Drug-induced osteoporosis with pathological fracture (finn-b-OSTPOPATFRACTURE) | rs3781735 | 41.1165714336115 | 20.2569307956799 | 0.0423816255765067 |
| Mozzarella | Injuries to the abdomen, lower back, lumbar spine and pelvis (finn-b-ST19_INJURI_ABDOMEN_LOWER_BACK_LUMBAR_SPINE_PELVIS) | rs3781735 | -7.12961642663625 | 3.39575545268654 | 0.0357669394747318 |
| Mozzarella | Injuries to the abdomen, lower back, lumbar spine and pelvis (finn-b-ST19_INJURI_ABDOMEN_LOWER_BACK_LUMBAR_SPINE_PELVIS) | rs7514341 | -6.33335817003204 | 2.73558495747602 | 0.0206033515179539 |
| Mozzarella | Injuries to the abdomen, lower back, lumbar spine and pelvis (finn-b-ST19_INJURI_ABDOMEN_LOWER_BACK_LUMBAR_SPINE_PELVIS) | rs7950374 | 6.70756535652315 | 3.22706544860434 | 0.0376601998258672 |
| Mozzarella | Injuries to the ankle and foot (finn-b-ST19_INJURI_ANKLE_FOOT) | rs117549105 | 13.2284624390981 | 5.36786645012652 | 0.013725053372599 |
| Mozzarella | Injuries to the ankle and foot (finn-b-ST19_INJURI_ANKLE_FOOT) | All - Inverse variance weighted | 1.02477237993417 | 0.47101952733175 | 0.0295816409121717 |
| Mozzarella | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | rs7950374 | -35.3118679978171 | 14.4457641809252 | 0.0145075422497357 |
| Mozzarella | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | All - MR Egger | 14.6435140506908 | 4.97914856320502 | 0.0080789278557519 |
| Mozzarella | Lumbar spine bone mineral density (ieu-a-982) | All - Inverse variance weighted | 0.697462959036472 | 0.336903517447231 | 0.0384321475031432 |
| Mozzarella | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | rs117549105 | -9.40438871473354 | 4.54639876118896 | 0.0385896654128533 |
| Mozzarella | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | All - Inverse variance weighted | -2.03878810189074 | 0.926842067259741 | 0.0278271445649481 |
| Mozzarella | Bone morphogenetic protein receptor type-1A (prot-a-259) | rs116735069 | 8.60018882791814 | 4.28412212765051 | 0.0447010775904983 |
| Mozzarella | Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) | All - MR Egger | -0.0873298606055993 | 0.0412505266828641 | 0.0469838905537351 |
| Mozzarella | Fractured/broken bones in last 5 years (ukb-a-308) | All - Inverse variance weighted | 0.0545715240351117 | 0.0257350983064333 | 0.0339630894701704 |
| Mozzarella | Fractured bone site(s): Arm (ukb-a-440) | rs7514341 | 0.0911577804506796 | 0.042239826710805 | 0.0309200385797062 |
| Mozzarella | Fractured bone site(s): Arm (ukb-a-440) | rs75314632 | 0.0764348640863819 | 0.0380407914371694 | 0.0445067158517043 |
| Mozzarella | Fractured bone site(s): Arm (ukb-a-440) | All - Inverse variance weighted | 0.0214190299303758 | 0.0087441864057242 | 0.0143048107857162 |
| Mozzarella | Fractured bone site(s): Arm (ukb-a-440) | All - MR Egger | 0.0321235870557741 | 0.0149591501228016 | 0.0441990712028187 |
| Mozzarella | Fractured bone site(s): Other bones (ukb-a-441) | rs141366068 | 0.211833501597606 | 0.0871956316423679 | 0.0151236286825455 |
| Mozzarella | Fractured bone site(s): Other bones (ukb-a-441) | rs62164517 | 0.169721248130152 | 0.083129854160609 | 0.0411872393117599 |
| Mozzarella | Fractured bone site(s): Other bones (ukb-a-441) | All - Inverse variance weighted | 0.0427372599416544 | 0.019376864977719 | 0.0274132974302683 |
| Mozzarella | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | rs352863 | 0.0564641083521445 | 0.0212994311512415 | 0.0080261468245865 |
| Mozzarella | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | rs77271533 | 0.0466786899000515 | 0.0212498972835277 | 0.0280451058127438 |
| Mozzarella | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | All - Inverse variance weighted | 0.0113138438578563 | 0.00439781962389 | 0.0100936923101568 |
| Mozzarella | Diagnoses - main ICD10: M67 Other disorders of synovium and tendon (ukb-a-570) | rs352863 | -0.0711656884875847 | 0.0310549887133183 | 0.021928593484461 |
| Mozzarella | Diagnoses - main ICD10: M67 Other disorders of synovium and tendon (ukb-a-570) | All - MR Egger | -0.0227948091844009 | 0.010831659748776 | 0.0481854891549373 |
| Mozzarella | Fractured heel (ukb-b-18389) | rs75314632 | -0.0699329231714995 | 0.0231681283433064 | 0.0025403201560805 |
| Mozzarella | Fractured heel (ukb-b-18389) | All - Inverse variance weighted | -0.0141272005727577 | 0.0052901070799567 | 0.0075739667341402 |
| Mozzarella | Ankle spacing width (left) (ukb-b-2122) | rs117549105 | 1.60675775201118 | 0.533042829625713 | 0.0025756221957765 |
| Mozzarella | Ankle spacing width (left) (ukb-b-2122) | rs12162199 | 1.32151202329677 | 0.508958620328875 | 0.0094178385586441 |
| Mozzarella | Ankle spacing width (left) (ukb-b-2122) | rs3781735 | 1.41309732587933 | 0.535756128897585 | 0.0083500995879756 |
| Mozzarella | Ankle spacing width (left) (ukb-b-2122) | rs62164517 | 1.10011875943682 | 0.481000241722747 | 0.0221871837378336 |
| Mozzarella | Ankle spacing width (left) (ukb-b-2122) | All - Inverse variance weighted | 0.274365121668929 | 0.134416410288319 | 0.0412351319181644 |
| Mozzarella | Diagnoses - secondary ICD10: M47.82 Other spondylosis (Cervical region) (ukb-b-2625) | rs7950374 | -0.0397873515930045 | 0.01664761965908 | 0.0168496387561052 |
| Mozzarella | Diagnoses - secondary ICD10: M47.82 Other spondylosis (Cervical region) (ukb-b-2625) | All - Inverse variance weighted | -0.026647955585627 | 0.0129690443197343 | 0.0399045604388291 |
| Mozzarella | Fractured heel (left) (ukb-b-8221) | rs116968441 | 0.131697526329359 | 0.0593769665584569 | 0.0265555047595782 |
| Mozzarella | Fractured heel (left) (ukb-b-8221) | rs12878562 | -0.121043332358811 | 0.0615044933965502 | 0.0490633809254906 |
| Mozzarella | Fractured heel (left) (ukb-b-8221) | rs73211188 | 0.130136801505982 | 0.0602707210438856 | 0.0308343187336986 |
| Mozzarella | Ankle spacing width (right) (ukb-b-8607) | rs117549105 | 1.07631623673377 | 0.539775087812063 | 0.0461511006021251 |
| Mozzarella | Ankle spacing width (right) (ukb-b-8607) | rs12162199 | 1.2690376131271 | 0.515257990827768 | 0.0137811852828187 |
| Mozzarella | Ankle spacing width (right) (ukb-b-8607) | rs62164517 | 1.16431541665645 | 0.487176433083086 | 0.0168517873562806 |
| Mozzarella | Ankle spacing width (right) (ukb-b-8607) | All - Inverse variance weighted | 0.291463755194419 | 0.119203584840839 | 0.0144815116692634 |
| Mozzarella | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | rs117549105 | 0.0804679533179741 | 0.0366055444347925 | 0.0279316547946706 |
| Mozzarella | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | All - MR Egger | -0.0287048943857359 | 0.0136613451493906 | 0.0485033214436446 |
| Mozzarella | Other/unspecified rheumatoid arthritis (ukb-d-RHEUMA_NOS) | rs12878562 | 0.0524212861155953 | 0.0242624346963938 | 0.030726666604773 |
| Mozzarella | Other/unspecified rheumatoid arthritis (ukb-d-RHEUMA_NOS) | rs142176727 | -0.0492001448472713 | 0.0245473877788665 | 0.0450387384334332 |
| Mozzarella | Diagnoses - main ICD10: S62 Fracture at wrist and hand level (ukb-d-S62) | rs116968441 | 0.0681358619867542 | 0.0275935839254378 | 0.0135391037183849 |
| Mozzarella | Diagnoses - main ICD10: S62 Fracture at wrist and hand level (ukb-d-S62) | rs117549105 | 0.061349001019753 | 0.02875 | 0.032852744529309 |
| Mozzarella | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) | rs148683239 | 16.4794996722023 | 7.9944911117295 | 0.0392690004335699 |
| Mozzarella | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) | All - Inverse variance weighted | 3.89076727123865 | 1.8570203435655 | 0.0361561722136492 |