ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Lobster/crab (ukb-b-14746)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Lobster/crab (👉 📊) Rheumatoid arthritis (ebi-a-GCST002318) MR Egger 34 3.909579228 1.661117383 0.024900457
Lobster/crab (👉 📊) Total body bone mineral density (age 15-30) (ebi-a-GCST005344) MR Egger 42 5.722056847 2.564911305 0.031360871
Lobster/crab (👉 📊) Total body bone mineral density (age 0-15) (ebi-a-GCST005345) MR Egger 55 -2.449277309 1.203446517 0.046843102
Lobster/crab (👉 📊) Total body bone mineral density (age over 60) (ebi-a-GCST005349) MR Egger 57 2.573713261 1.069570476 0.019501893
Lobster/crab (👉 📊) Osteoarthritis of the hip (hospital diagnosed) (ebi-a-GCST005810) Inverse variance weighted 57 -3.002209455 1.484246271 0.043102383
Lobster/crab (👉 📊) Rheumatoid arthritis (ebi-a-GCST90018690) Inverse variance weighted 19 2.746030562 0.992784995 0.005675077
Lobster/crab (👉 📊) Rheumatoid arthritis (ebi-a-GCST90018910) MR Egger 57 2.402499824 1.092207592 0.032050891
Lobster/crab (👉 📊) Rheumatoid arthritis (ebi-a-GCST90018910) Inverse variance weighted 57 1.132357043 0.577099486 0.049744764
Lobster/crab (👉 📊) Arthritis (not osteoarthritis) (ebi-a-GCST90038699) MR Egger 46 0.040901644 0.018132896 0.029115012
Lobster/crab (👉 📊) Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) Inverse variance weighted 54 17.59678566 6.283219559 0.005100768
Lobster/crab (👉 📊) Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) Inverse variance weighted 54 17.57301074 6.296570474 0.005256397
Lobster/crab (👉 📊) Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) Weighted median 54 -13.64496021 5.407626224 0.011626547
Lobster/crab (👉 📊) Carcinoma in situ of skin of upper limb, including shoulder (finn-b-CD2_INSITU_SKIN_UPPERLIMB) MR Egger 54 -17.53312836 8.715746485 0.049450925
Lobster/crab (👉 📊) Drug-induced osteoporosis (finn-b-DRUGADVERS_OSTEOPO) Weighted median 54 -16.45579556 7.275462696 0.023708454
Lobster/crab (👉 📊) Drug-induced osteoporosis (finn-b-DRUGADVERS_OSTEOPO) Inverse variance weighted 54 -18.87069652 5.130690886 0.000235067
Lobster/crab (👉 📊) Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) Simple mode 54 -19.94970638 9.414342172 0.038787204
Lobster/crab (👉 📊) Ankylosing hyperostosis [Forestier] (finn-b-M13_FORESTIER) Inverse variance weighted 54 8.929254298 4.347880432 0.040004464
Lobster/crab (👉 📊) Other intervertebral disc disorders (finn-b-M13_INTERVERTEB) Inverse variance weighted 54 -0.938710163 0.471442934 0.0464652
Lobster/crab (👉 📊) Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) Inverse variance weighted 54 -5.750271492 2.353920999 0.014571868
Lobster/crab (👉 📊) Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) Inverse variance weighted 54 12.92796224 6.18604602 0.036630492
Lobster/crab (👉 📊) Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) Weighted median 54 -12.12554083 6.171043698 0.049424742
Lobster/crab (👉 📊) Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) Inverse variance weighted 54 -9.404487363 4.302770742 0.028838899
Lobster/crab (👉 📊) Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) Inverse variance weighted 54 6.523450564 3.318324811 0.049311701
Lobster/crab (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) Inverse variance weighted 54 -1.898601349 0.87935435 0.030843524
Lobster/crab (👉 📊) Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) Weighted median 54 -1.529987743 0.731635331 0.036511127
Lobster/crab (👉 📊) Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) Inverse variance weighted 54 -1.28704906 0.485249849 0.007993528
Lobster/crab (👉 📊) Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) Simple mode 54 -2.896559488 1.433286545 0.048352337
Lobster/crab (👉 📊) Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) Inverse variance weighted 54 -1.680557431 0.802902003 0.036339868
Lobster/crab (👉 📊) Open wound of wrist and hand (finn-b-ST19_OPEN_WOUND_WRIST_HAND) Inverse variance weighted 54 1.465000516 0.712447321 0.039754272
Lobster/crab (👉 📊) Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) Inverse variance weighted 54 12.053523 5.869305296 0.04000918
Lobster/crab (👉 📊) Rheumatoid arthritis (ieu-a-833) MR Egger 17 4.823656405 2.250501073 0.048885009
Lobster/crab (👉 📊) Psoriatic arthritis (ieu-b-5116) Inverse variance weighted 45 -3.171993535 1.337637569 0.017723716
Lobster/crab (👉 📊) Osteomodulin (prot-a-2147) Weighted median 51 -3.517678414 1.60608822 0.028508652
Lobster/crab (👉 📊) Osteomodulin (prot-a-2147) Inverse variance weighted 51 -2.703838625 1.149045495 0.018616769
Lobster/crab (👉 📊) Fractured bone site(s): Ankle (ukb-a-438) Weighted median 54 -0.049372306 0.019758262 0.012460819
Lobster/crab (👉 📊) Fractured bone site(s): Ankle (ukb-a-438) Inverse variance weighted 54 -0.030103965 0.01479841 0.041924356
Lobster/crab (👉 📊) Heel bone mineral density (BMD) (left) (ukb-b-1096) MR Egger 57 -0.722561139 0.321334655 0.028562808
Lobster/crab (👉 📊) Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) Weighted median 3 0.069833194 0.034654224 0.043889736
Lobster/crab (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) MR Egger 57 -0.708981381 0.318700011 0.030230116
Lobster/crab (👉 📊) Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy (ukb-b-18279) Inverse variance weighted 5 0.04622547 0.022021388 0.03580659
Lobster/crab (👉 📊) Operative procedures - main OPCS: W38.1 Primary total prosthetic replacement of hip joint not using cement (ukb-b-8136) Weighted median 5 -0.078057594 0.032267672 0.015560463
Lobster/crab (👉 📊) Operative procedures - main OPCS: W38.1 Primary total prosthetic replacement of hip joint not using cement (ukb-b-8136) Inverse variance weighted 5 -0.071265963 0.024694781 0.003903315
Lobster/crab (👉 📊) Fractured/broken bones in last 5 years (ukb-e-2463_CSA) Weighted mode 25 -14.29139282 6.505285074 0.037924689
Lobster/crab (👉 📊) Ankle spacing width (ukb-e-3143_EAS) MR Egger 15 -7.43369608 3.285406986 0.041428506
Lobster/crab (👉 📊) Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) Simple mode 17 -12.11799106 5.593523683 0.045721007
Lobster/crab (👉 📊) Knee pain for 3+ months (ukb-e-3773_CSA) MR Egger 30 12.72031825 6.050875525 0.044652381
Lobster/crab (👉 📊) Ankle spacing width (left) (ukb-e-4100_AFR) MR Egger 18 3.96300243 1.859360836 0.048911891
Lobster/crab (👉 📊) Ankle spacing width (left) (ukb-e-4100_EAS) Inverse variance weighted 16 3.998009059 1.715736232 0.019795568
Lobster/crab (👉 📊) Ankle spacing width (right) (ukb-e-4119_AFR) MR Egger 18 4.158865771 1.918158444 0.045569218
Lobster/crab (👉 📊) Ankle spacing width (right) (ukb-e-4119_EAS) Weighted median 16 5.28481178 2.577545445 0.040332503
Lobster/crab (👉 📊) Ankle spacing width (right) (ukb-e-4119_EAS) Inverse variance weighted 16 5.023758618 2.243824251 0.025160669
Lobster/crab (👉 📊) Ankle spacing width (right) (ukb-e-4119_EAS) Weighted mode 16 4.593110206 1.884712518 0.027738489
Lobster/crab (👉 📊) M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_CSA) Inverse variance weighted 25 -7.418121841 3.28551487 0.023956492

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Lobster/crab Rheumatoid arthritis (ebi-a-GCST002318) rs217514 -17.2628571236256 5.50989294284339 0.0017299065833724
Lobster/crab Rheumatoid arthritis (ebi-a-GCST002318) All - MR Egger 3.9095792279605 1.66111738258968 0.0249004570484381
Lobster/crab Total body bone mineral density (age 15-30) (ebi-a-GCST005344) rs117123413 25.2288380588764 11.6187245497058 0.0299013417240028
Lobster/crab Total body bone mineral density (age 15-30) (ebi-a-GCST005344) rs143695299 30.5175468355385 10.3283199517509 0.0031292806081428
Lobster/crab Total body bone mineral density (age 15-30) (ebi-a-GCST005344) rs186181876 29.1908396946565 10.0424088210348 0.0036519705452261
Lobster/crab Total body bone mineral density (age 15-30) (ebi-a-GCST005344) All - MR Egger 5.72205684732583 2.56491130525718 0.0313608707279129
Lobster/crab Total body bone mineral density (age 0-15) (ebi-a-GCST005345) All - MR Egger -2.44927730865484 1.20344651686052 0.0468431016360294
Lobster/crab Total body bone mineral density (age over 60) (ebi-a-GCST005349) rs10981135 -9.3461708899005 3.49138567726168 0.0074301691584902
Lobster/crab Total body bone mineral density (age over 60) (ebi-a-GCST005349) rs116077835 6.93677332384715 3.08925127782667 0.024738967141598
Lobster/crab Total body bone mineral density (age over 60) (ebi-a-GCST005349) rs138084455 8.12094621508023 4.03074782856837 0.0439309276825129
Lobster/crab Total body bone mineral density (age over 60) (ebi-a-GCST005349) rs143695299 10.0343020845113 4.39519016924875 0.0224292569767125
Lobster/crab Total body bone mineral density (age over 60) (ebi-a-GCST005349) rs146893734 -9.27803465892667 4.09229533380896 0.0233782692975352
Lobster/crab Total body bone mineral density (age over 60) (ebi-a-GCST005349) rs55990710 6.74023353915755 2.78168368282692 0.0153896675618411
Lobster/crab Total body bone mineral density (age over 60) (ebi-a-GCST005349) rs72784354 13.0551745964764 4.77371030699441 0.0062416931139245
Lobster/crab Total body bone mineral density (age over 60) (ebi-a-GCST005349) All - MR Egger 2.57371326084695 1.06957047556143 0.0195018927238453
Lobster/crab Osteoarthritis of the hip (hospital diagnosed) (ebi-a-GCST005810) rs116077835 -29.0243582782573 13.3435996330344 0.0296187230342838
Lobster/crab Osteoarthritis of the hip (hospital diagnosed) (ebi-a-GCST005810) All - Inverse variance weighted -3.00220945478376 1.48424627148358 0.0431023825701358
Lobster/crab Rheumatoid arthritis (ebi-a-GCST90018690) rs116077835 4.77111456441557 2.10351332122596 0.0233191729084002
Lobster/crab Rheumatoid arthritis (ebi-a-GCST90018690) All - Inverse variance weighted 2.74603056239391 0.992784995205761 0.0056750766981931
Lobster/crab Rheumatoid arthritis (ebi-a-GCST90018910) rs116077835 4.61047349796858 1.99865196307877 0.0210664424839068
Lobster/crab Rheumatoid arthritis (ebi-a-GCST90018910) rs143695299 10.403709148479 4.9153756266727 0.0342968327099919
Lobster/crab Rheumatoid arthritis (ebi-a-GCST90018910) rs72908058 10.2770130635571 4.83075568686258 0.0333857723703581
Lobster/crab Rheumatoid arthritis (ebi-a-GCST90018910) rs72952065 -12.2519946052225 5.97975333517492 0.0404706186592943
Lobster/crab Rheumatoid arthritis (ebi-a-GCST90018910) All - Inverse variance weighted 1.13235704349977 0.577099486138215 0.0497447636491503
Lobster/crab Rheumatoid arthritis (ebi-a-GCST90018910) All - MR Egger 2.40249982379792 1.09220759211737 0.0320508912572911
Lobster/crab Arthritis (not osteoarthritis) (ebi-a-GCST90038699) rs186181876 0.118930619168787 0.0577734351145038 0.0395355174103978
Lobster/crab Arthritis (not osteoarthritis) (ebi-a-GCST90038699) rs2808659 0.121095001765201 0.0530626239035386 0.0224825607404041
Lobster/crab Arthritis (not osteoarthritis) (ebi-a-GCST90038699) rs72784354 -0.134847206104723 0.0602094102753455 0.0251145168408775
Lobster/crab Arthritis (not osteoarthritis) (ebi-a-GCST90038699) All - MR Egger 0.0409016438860346 0.0181328962007914 0.0291150119001901
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) rs149425396 97.2255400820824 43.7068941653398 0.0261155082920262
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) rs217514 113.754539243633 51.7616808747657 0.0279733941202927
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) rs3134489 99.2029041544408 42.1820261671552 0.018683751920793
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) rs58783475 272.781723765772 100.597266249654 0.0066954970420722
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) rs74919141 103.390400230493 45.0010632873185 0.0215896840023004
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) rs75589235 52.1543363812691 21.0931005818786 0.0134142438582862
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) All - Inverse variance weighted 17.5967856622087 6.28321955879229 0.0051007676643975
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) rs149425396 99.7989462363166 44.0862408892707 0.0235912843434445
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) rs217514 113.283366595879 51.7616808747657 0.0286290855759153
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) rs3134489 98.7651799119591 42.1820261671552 0.0192113474807507
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) rs58783475 268.679403072785 99.5801619456075 0.0069731927781233
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) rs74919141 102.898772760637 44.9553304994249 0.0220844952170102
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) rs75589235 52.3067331670823 21.1346633416459 0.0133263690074413
Lobster/crab Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) All - Inverse variance weighted 17.5730107396414 6.29657047426879 0.0052563973127848
Lobster/crab Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) rs116077835 130.090243582783 57.3336953062103 0.0232682315413362
Lobster/crab Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) rs12064617 184.982755331615 66.3039078830895 0.0052720681997581
Lobster/crab Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) rs138793955 116.033079962353 41.3786184194811 0.0050444787992295
Lobster/crab Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) rs144063850 -56.3158340031304 23.6843775117391 0.0174180219346402
Lobster/crab Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) rs151163598 63.9876635571095 29.1234713040292 0.0280121166563362
Lobster/crab Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) rs457294 71.3845248094848 34.0808449410373 0.0362097319265406
Lobster/crab Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) rs74510013 69.4933338651616 33.7345312764875 0.0393979756483865
Lobster/crab Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) rs74919141 59.669855004196 26.7308145238188 0.0255984585990358
Lobster/crab Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) rs75589235 -33.1255195344971 12.6350789692436 0.0087489707574757
Lobster/crab Carcinoma in situ of skin of upper limb, including shoulder (finn-b-CD2_INSITU_SKIN_UPPERLIMB) rs116077835 140.51412630357 69.1149763157402 0.0420475832640536
Lobster/crab Carcinoma in situ of skin of upper limb, including shoulder (finn-b-CD2_INSITU_SKIN_UPPERLIMB) rs144063850 57.2253479419603 28.9035069165362 0.047717509378994
Lobster/crab Carcinoma in situ of skin of upper limb, including shoulder (finn-b-CD2_INSITU_SKIN_UPPERLIMB) rs457294 84.8087742315315 42.5566470335961 0.0462784920188854
Lobster/crab Carcinoma in situ of skin of upper limb, including shoulder (finn-b-CD2_INSITU_SKIN_UPPERLIMB) All - MR Egger -17.5331283629896 8.71574648545594 0.0494509252954193
Lobster/crab Drug-induced osteoporosis (finn-b-DRUGADVERS_OSTEOPO) rs1395502 -122.968685335908 51.5105531797489 0.0169748384559539
Lobster/crab Drug-induced osteoporosis (finn-b-DRUGADVERS_OSTEOPO) rs217514 -103.018533912651 44.4921600236933 0.0205893476169188
Lobster/crab Drug-induced osteoporosis (finn-b-DRUGADVERS_OSTEOPO) All - Inverse variance weighted -18.8706965216864 5.13069088562219 0.0002350671863513
Lobster/crab Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) rs9301989 78.0114320294154 31.474258200738 0.0131906936492191
Lobster/crab Ankylosing hyperostosis [Forestier] (finn-b-M13_FORESTIER) rs116918010 87.5853586122068 37.5971740012967 0.0198287345313754
Lobster/crab Ankylosing hyperostosis [Forestier] (finn-b-M13_FORESTIER) rs74919141 68.0618215826746 32.8247085106432 0.0381263701872708
Lobster/crab Ankylosing hyperostosis [Forestier] (finn-b-M13_FORESTIER) All - Inverse variance weighted 8.92925429832352 4.34788043168608 0.0400044635732024
Lobster/crab Other intervertebral disc disorders (finn-b-M13_INTERVERTEB) rs188857983 -6.89725271533949 3.25259917523378 0.0339608929706045
Lobster/crab Other intervertebral disc disorders (finn-b-M13_INTERVERTEB) rs217514 -11.341798735238 4.07227788416557 0.0053507262005622
Lobster/crab Other intervertebral disc disorders (finn-b-M13_INTERVERTEB) All - Inverse variance weighted -0.938710163302471 0.471442934379083 0.0464651998069518
Lobster/crab Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) rs146893734 63.4414038521707 31.8939207761937 0.0466859935319356
Lobster/crab Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) rs3134489 -39.657816368844 16.5751579819745 0.0167292116666386
Lobster/crab Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) All - Inverse variance weighted -5.75027149208741 2.353920998847 0.0145718682041578
Lobster/crab Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) rs118099326 87.021492030311 37.439574078913 0.0201084337730212
Lobster/crab Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) rs149425396 -87.4342935590002 42.2305177262573 0.0384143930126462
Lobster/crab Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) rs151163598 165.022825472922 54.7047956394949 0.0025562166150542
Lobster/crab Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) rs17688110 120.265190554179 44.8043114077661 0.0072696523528177
Lobster/crab Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) rs74919141 97.8224333044455 43.4690148928824 0.0244239119847209
Lobster/crab Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) All - Inverse variance weighted 12.9279622366944 6.18604602008477 0.0366304924148865
Lobster/crab Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) All - Inverse variance weighted -9.40448736314764 4.30277074225024 0.0288388990833776
Lobster/crab Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) rs144509894 187.291639552695 78.5938110064373 0.0171706583894057
Lobster/crab Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) rs9301989 87.3188667951509 33.9080043938985 0.0100190905039911
Lobster/crab Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) All - Inverse variance weighted 6.523450563697 3.31832481059557 0.0493117013910575
Lobster/crab Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) rs10281272 -17.9292814670237 8.52694579715596 0.0354953612996384
Lobster/crab Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) rs35976064 -15.1087832393231 7.09553227683767 0.033226344090106
Lobster/crab Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) rs75589235 -6.33139373787753 3.11027985591577 0.0417870462631175
Lobster/crab Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) All - Inverse variance weighted -1.89860134871892 0.879354350227879 0.0308435236230971
Lobster/crab Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs35976064 -11.3371832751365 3.92828364222401 0.0039012271280975
Lobster/crab Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs55990710 -8.2839151433637 3.72164822400196 0.0260227101258546
Lobster/crab Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) All - Inverse variance weighted -1.28704905969445 0.485249848573676 0.0079935282947826
Lobster/crab Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs118099326 -13.865299189966 5.29135092761955 0.0087834316053037
Lobster/crab Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs146893734 24.8352526342798 10.8586566661651 0.0221877353968312
Lobster/crab Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs55990710 -14.3210857736749 6.13651647612643 0.019608897860603
Lobster/crab Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs6554575 -14.1187999234963 6.1245935741194 0.0211518395721945
Lobster/crab Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs74002881 -11.8469765528589 5.5578408519585 0.0330414759684301
Lobster/crab Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) All - Inverse variance weighted -1.68055743094686 0.802902003397666 0.036339867723183
Lobster/crab Open wound of wrist and hand (finn-b-ST19_OPEN_WOUND_WRIST_HAND) rs116077835 -21.4890191159125 10.3255883619479 0.0374208794746212
Lobster/crab Open wound of wrist and hand (finn-b-ST19_OPEN_WOUND_WRIST_HAND) rs217514 12.4187647872487 6.15889960993636 0.0437588506629623
Lobster/crab Open wound of wrist and hand (finn-b-ST19_OPEN_WOUND_WRIST_HAND) All - Inverse variance weighted 1.46500051551274 0.712447321169633 0.0397542723291723
Lobster/crab Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) rs138793955 132.272073612949 67.0628872825604 0.0485686654533469
Lobster/crab Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) rs3134489 112.028224459155 41.5400306115154 0.0069993769579302
Lobster/crab Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) rs72878659 138.981662647313 59.8443827637985 0.0202122450723132
Lobster/crab Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) All - Inverse variance weighted 12.0535229960232 5.86930529574539 0.040009180165938
Lobster/crab Rheumatoid arthritis (ieu-a-833) rs217514 -17.2628571236256 5.42424048651941 0.0014598983168658
Lobster/crab Rheumatoid arthritis (ieu-a-833) All - MR Egger 4.82365640492634 2.25050107299709 0.0488850085129113
Lobster/crab Psoriatic arthritis (ieu-b-5116) rs145421886 -22.8109498672338 9.36953573225168 0.0149087954662782
Lobster/crab Psoriatic arthritis (ieu-b-5116) rs146893734 -16.4915171481249 7.41225111969747 0.0260879553652932
Lobster/crab Psoriatic arthritis (ieu-b-5116) rs150869774 -17.6243462209004 7.11046730249889 0.0131881350532773
Lobster/crab Psoriatic arthritis (ieu-b-5116) rs457294 -25.2813636398241 9.03358092487749 0.0051324954525704
Lobster/crab Psoriatic arthritis (ieu-b-5116) All - Inverse variance weighted -3.17199353533941 1.33763756910134 0.0177237163719481
Lobster/crab Osteomodulin (prot-a-2147) rs138793955 -14.3709599591039 7.23325577728834 0.0469456776473221
Lobster/crab Osteomodulin (prot-a-2147) rs72952065 -15.8755951317008 8.01091954956858 0.047507852697887
Lobster/crab Osteomodulin (prot-a-2147) All - Inverse variance weighted -2.70383862485504 1.14904549457656 0.0186167693115501
Lobster/crab Fractured bone site(s): Ankle (ukb-a-438) rs140747487 0.178338491758366 0.0863914501528143 0.0389885996830405
Lobster/crab Fractured bone site(s): Ankle (ukb-a-438) rs188857983 -0.23768441075681 0.100065342394145 0.0175350705569392
Lobster/crab Fractured bone site(s): Ankle (ukb-a-438) rs72908058 -0.20108253691145 0.0937554555831599 0.031972394132758
Lobster/crab Fractured bone site(s): Ankle (ukb-a-438) rs74525102 -0.193570592405731 0.0960462317191802 0.0438638259666713
Lobster/crab Fractured bone site(s): Ankle (ukb-a-438) All - Inverse variance weighted -0.0301039645444244 0.0147984097173144 0.0419243556137468
Lobster/crab Heel bone mineral density (BMD) (left) (ukb-b-1096) rs118099326 2.61952083877711 1.17641102691403 0.025966966314761
Lobster/crab Heel bone mineral density (BMD) (left) (ukb-b-1096) rs147611679 -3.10206067544362 1.25754800437113 0.0136344261536787
Lobster/crab Heel bone mineral density (BMD) (left) (ukb-b-1096) rs217514 4.05380118533576 1.20349273552743 0.0007561578787253
Lobster/crab Heel bone mineral density (BMD) (left) (ukb-b-1096) rs3134489 -2.37361806808946 1.20415458669347 0.0487020914458341
Lobster/crab Heel bone mineral density (BMD) (left) (ukb-b-1096) rs73215950 2.82099478057267 1.20211866473716 0.0189412206827614
Lobster/crab Heel bone mineral density (BMD) (left) (ukb-b-1096) All - MR Egger -0.722561139110268 0.321334654695222 0.0285628076905593
Lobster/crab Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) rs217514 0.11117587865285 0.0462105939804329 0.0161347723380131
Lobster/crab Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs118099326 2.58704598902535 1.17683564149464 0.0279272383042343
Lobster/crab Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs147611679 -3.26374043815372 1.25717853983452 0.0094293152818687
Lobster/crab Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs217514 4.03306958883455 1.20392352194823 0.000808295454257
Lobster/crab Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs73215950 2.67917594835856 1.20233817336303 0.025860195069017
Lobster/crab Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) All - MR Egger -0.708981380856247 0.318700010856527 0.0302301160197857
Lobster/crab Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy (ukb-b-18279) All - Inverse variance weighted 0.0462254700160722 0.0220213882747687 0.0358065901083151
Lobster/crab Operative procedures - main OPCS: W38.1 Primary total prosthetic replacement of hip joint not using cement (ukb-b-8136) rs457294 -0.139989544818976 0.0531805828002122 0.0084798158335153
Lobster/crab Operative procedures - main OPCS: W38.1 Primary total prosthetic replacement of hip joint not using cement (ukb-b-8136) All - Inverse variance weighted -0.0712659626210237 0.0246947806854596 0.0039033154821281
Lobster/crab Fractured/broken bones in last 5 years (ukb-e-2463_CSA) rs116077835 -14.1356649379341 6.23467076070472 0.0233739037757456
Lobster/crab Fractured/broken bones in last 5 years (ukb-e-2463_CSA) rs72784354 25.4685796673348 11.9122973590744 0.0325161442608906
Lobster/crab Fractured/broken bones in last 5 years (ukb-e-2463_CSA) rs72878659 -85.8351913363971 38.2945806980025 0.0249972730071389
Lobster/crab Ankle spacing width (ukb-e-3143_EAS) rs116077835 -5.89298084664208 2.93900132931419 0.0449527473104583
Lobster/crab Ankle spacing width (ukb-e-3143_EAS) rs3134489 -13.8364633048472 6.39077394023313 0.0303824403742537
Lobster/crab Ankle spacing width (ukb-e-3143_EAS) rs6554575 25.0571091488534 9.44047002494966 0.0079491362334139
Lobster/crab Ankle spacing width (ukb-e-3143_EAS) All - MR Egger -7.43369607967785 3.28540698605087 0.0414285058685215
Lobster/crab Knee pain for 3+ months (ukb-e-3773_CSA) rs72878659 -91.4592528552578 46.5395640897302 0.0493918360205001
Lobster/crab Knee pain for 3+ months (ukb-e-3773_CSA) rs74919141 93.5349844394189 44.8638649236377 0.0370817938922067
Lobster/crab Knee pain for 3+ months (ukb-e-3773_CSA) All - MR Egger 12.7203182528026 6.05087552454694 0.0446523805869902
Lobster/crab Ankle spacing width (left) (ukb-e-4100_AFR) All - MR Egger 3.96300242969332 1.85936083553458 0.0489118906151583
Lobster/crab Ankle spacing width (left) (ukb-e-4100_EAS) rs35976064 21.2530217566479 8.77092846270928 0.0153877964525524
Lobster/crab Ankle spacing width (left) (ukb-e-4100_EAS) All - Inverse variance weighted 3.9980090590497 1.71573623198674 0.0197955678602015
Lobster/crab Ankle spacing width (right) (ukb-e-4119_AFR) rs2808659 -14.6800233549684 7.42742307796757 0.0481024163283534
Lobster/crab Ankle spacing width (right) (ukb-e-4119_AFR) All - MR Egger 4.15886577063995 1.91815844391089 0.0455692176351282
Lobster/crab Ankle spacing width (right) (ukb-e-4119_EAS) rs35976064 29.6020234577849 8.92201629510251 0.0009070912007057
Lobster/crab Ankle spacing width (right) (ukb-e-4119_EAS) rs6128982 5.76709772118942 2.48935647345594 0.0205199574097476
Lobster/crab Ankle spacing width (right) (ukb-e-4119_EAS) rs6554575 -21.8981082527287 9.5135353517988 0.021347327853052
Lobster/crab Ankle spacing width (right) (ukb-e-4119_EAS) All - Inverse variance weighted 5.02375861820423 2.24382425096059 0.0251606687054298
Lobster/crab M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_CSA) rs3134489 -36.2289764694038 18.1801468710742 0.0462858838577876
Lobster/crab M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_CSA) All - Inverse variance weighted -7.41812184058923 3.28551487044782 0.0239564916836785