ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Canned soup | Knee osteoarthritis (ebi-a-GCST007090) | All - Inverse variance weighted | 0.540774546942658 | 0.264748495413053 | 0.0410923242157442 |
| Canned soup | Osteoarthritis of the hip or knee (ebi-a-GCST007092) | rs141906452 | 1.36557940880581 | 0.631943662585666 | 0.0307015552023783 |
| Canned soup | Osteoarthritis of the hip or knee (ebi-a-GCST007092) | All - Inverse variance weighted | 0.567699885118995 | 0.216696063635923 | 0.0087981899464019 |
| Canned soup | Frozen shoulder (ebi-a-GCST90000513) | rs141906452 | 2.90548810384215 | 0.917044682775177 | 0.0015332432968687 |
| Canned soup | Frozen shoulder (ebi-a-GCST90000513) | All - Inverse variance weighted | 0.893578619236863 | 0.37980280042516 | 0.0186354774727922 |
| Canned soup | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | rs341745 | -14.6795535289675 | 7.44118387556998 | 0.0485246950891527 |
| Canned soup | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | All - MR Egger | 14.240124025117 | 5.174656013454 | 0.0249855532100308 |
| Canned soup | Rheumatoid arthritis (ebi-a-GCST90018910) | rs74379710 | 2.92283278591726 | 1.40605971140717 | 0.0376412398443135 |
| Canned soup | Rheumatoid arthritis (ebi-a-GCST90018910) | All - Inverse variance weighted | 0.870196941485277 | 0.365427866706641 | 0.0172511992953639 |
| Canned soup | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | rs341745 | 14.490726494531 | 5.07035555431225 | 0.0042641305755977 |
| Canned soup | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | All - Inverse variance weighted | 4.24643152570145 | 1.13710548540474 | 0.0001881469311838 |
| Canned soup | Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) | rs141906452 | -5.5567459985981 | 2.63491452417185 | 0.0349540412785909 |
| Canned soup | Infective bursitis (finn-b-M13_INFBURSA) | rs182387902 | 10.496759077773 | 4.13889927159019 | 0.0112087246010281 |
| Canned soup | Infective bursitis (finn-b-M13_INFBURSA) | All - Inverse variance weighted | 3.72232063762585 | 1.82711197971509 | 0.0416229806661436 |
| Canned soup | Lower back pain or/and sciatica (finn-b-M13_LOWBACKPAINORANDSCIATICA) | All - Inverse variance weighted | 0.571295958735789 | 0.270840549130557 | 0.0349148766860833 |
| Canned soup | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | All - Inverse variance weighted | -2.44843305381398 | 1.18763165818084 | 0.0392449011863376 |
| Canned soup | Pyogenic arthritis (finn-b-M13_PYOGARTH) | All - Inverse variance weighted | 2.18944903950057 | 1.04564428566689 | 0.0362710647776005 |
| Canned soup | Short Achilles tendon (acquired) (finn-b-M13_SHORTACHILLES) | rs141906452 | 8.29153667633952 | 3.80800534609811 | 0.0294510129750492 |
| Canned soup | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | rs147596965 | 2.11768428167718 | 1.05704444620219 | 0.0451342255568333 |
| Canned soup | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | rs182387902 | 2.32288884229335 | 0.860599319907741 | 0.0069516304279784 |
| Canned soup | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | All - Inverse variance weighted | 0.98681386190517 | 0.360036954959338 | 0.0061277071253292 |
| Canned soup | Other/unspecified synovitis and tenosynovitis (finn-b-M13_TENDOSYNOVITISNAS) | All - Inverse variance weighted | 1.99201327396099 | 0.786869624943924 | 0.0113554080456071 |
| Canned soup | Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) | rs141906452 | 19.0908727723078 | 6.14873919975594 | 0.0019037974384878 |
| Canned soup | Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) | All - MR Egger | 16.825014138443 | 6.85369318309849 | 0.0396337654982344 |
| Canned soup | Fracture of foot, except ankle (finn-b-ST19_FRACT_FOOT_ANKLE) | rs147596965 | 4.0843622138969 | 1.75095457585193 | 0.0196665817438312 |
| Canned soup | Injuries to the wrist and hand (finn-b-ST19_INJURI_WRIST_HAND) | rs141906452 | -1.28386255588525 | 0.544779019470402 | 0.0184397908009106 |
| Canned soup | Shoulder region (finn-b-Z21_SHOUL_REGION) | rs141906452 | 14.614605162326 | 6.37573045786861 | 0.0218926954978066 |
| Canned soup | Shoulder region (finn-b-Z21_SHOUL_REGION) | All - Inverse variance weighted | 7.66104316299117 | 3.05343707323852 | 0.0121076902915031 |
| Canned soup | Shoulder region (finn-b-Z21_SHOUL_REGION) | All - MR Egger | 16.4201709571123 | 6.89324905561938 | 0.0444022996892945 |
| Canned soup | Femoral neck bone mineral density (ieu-a-980) | rs147596965 | 1.79384756987639 | 0.684885702575018 | 0.0088138167134842 |
| Canned soup | Femoral neck bone mineral density (ieu-a-980) | All - Inverse variance weighted | 0.47876399361844 | 0.235744882079957 | 0.0422695675823509 |
| Canned soup | Osteocalcin (prot-a-246) | All - Inverse variance weighted | 1.48184444913443 | 0.703638679148115 | 0.0352066497127019 |
| Canned soup | Bone morphogenetic protein 10 (prot-a-254) | rs7310153 | -4.14039110771387 | 2.1073529099518 | 0.0494448569926383 |
| Canned soup | Bone morphogenetic protein 10 (prot-a-254) | All - Inverse variance weighted | -1.52152421559783 | 0.70351675131778 | 0.0305611392993195 |
| Canned soup | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | rs11543913 | -0.934257631060887 | 0.37529126587688 | 0.0127951665034551 |
| Canned soup | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | rs141906452 | 0.905048648766439 | 0.352232322828783 | 0.010185566073994 |
| Canned soup | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | All - MR Egger | 0.870656189913052 | 0.302384076163406 | 0.0236750552961223 |
| Canned soup | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | All - Inverse variance weighted | 0.0567463866965336 | 0.0244274869178207 | 0.0201762176119367 |
| Canned soup | Diagnoses - secondary ICD10: M81.99 Osteoporosis, unspecified (Site unspecified) (ukb-b-17796) | rs11543913 | 0.0254802821933739 | 0.0123236816847533 | 0.0386788896829411 |
| Canned soup | Diagnoses - secondary ICD10: M81.99 Osteoporosis, unspecified (Site unspecified) (ukb-b-17796) | All - Inverse variance weighted | 0.0183754910653774 | 0.0087956806036335 | 0.0366942745177521 |
| Canned soup | Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) | rs341745 | -0.0364691442638543 | 0.0129617170671665 | 0.0048989474478941 |
| Canned soup | Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) | All - Inverse variance weighted | -0.0255536295008845 | 0.0107121328989901 | 0.0170566302742883 |
| Canned soup | Shoulder lesions (ukb-d-M13_SHOULDER) | rs141906452 | -0.0601728402235773 | 0.0279722235337273 | 0.0314632575392169 |
| Canned soup | Shoulder lesions (ukb-d-M13_SHOULDER) | All - MR Egger | -0.0816972757334708 | 0.024115541887765 | 0.0116351620137455 |
| Canned soup | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | All - Inverse variance weighted | -0.0124627441375896 | 0.0063493111248704 | 0.0496636280564028 |
| Canned soup | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | rs141906452 | -0.0602327659157191 | 0.0279740394637922 | 0.0313055918778395 |
| Canned soup | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | All - MR Egger | -0.0819952680451488 | 0.0241171508067117 | 0.011444453291475 |
| Canned soup | Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) | All - Inverse variance weighted | -9.50265667782607 | 4.59375179656403 | 0.0385831940656968 |