ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Unsalted peanuts | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | rs142133433 | 7.30148208726094 | 3.61666594929626 | 0.0435035013051964 |
| Unsalted peanuts | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | rs1977495 | 6.94144238335525 | 3.45626956918895 | 0.0446047789210041 |
| Unsalted peanuts | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | rs72694839 | 6.01953038774145 | 2.96978851963746 | 0.0426703660547405 |
| Unsalted peanuts | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | All - Inverse variance weighted | 1.12759054466653 | 0.481287487743434 | 0.0191364193972578 |
| Unsalted peanuts | Rheumatoid arthritis (ebi-a-GCST90018690) | rs113430016 | -5.23236531037319 | 2.338743913926 | 0.0252697121585046 |
| Unsalted peanuts | Rheumatoid arthritis (ebi-a-GCST90018690) | rs12668323 | -4.91009926147231 | 2.4438425777269 | 0.0445189315440247 |
| Unsalted peanuts | Rheumatoid arthritis (ebi-a-GCST90018690) | rs9563880 | -5.37215539805311 | 2.52900038231921 | 0.0336516786930933 |
| Unsalted peanuts | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | rs113940640 | 127.46103892382 | 49.0058405791287 | 0.0092969885224393 |
| Unsalted peanuts | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | rs149876304 | -51.7691269217595 | 26.1188015071833 | 0.0474721178094408 |
| Unsalted peanuts | Juvenile rheumatoid arthritis (ebi-a-GCST90018873) | All - Inverse variance weighted | -5.09210319238947 | 2.13944089740042 | 0.0173075032451146 |
| Unsalted peanuts | Arthritis (not osteoarthritis) (ebi-a-GCST90038699) | rs56379516 | 0.0731108618866687 | 0.0369246020779137 | 0.0477030729082919 |
| Unsalted peanuts | Arthritis (not osteoarthritis) (ebi-a-GCST90038699) | rs6570675 | 0.0782369259584293 | 0.0386067313374523 | 0.0427125521054096 |
| Unsalted peanuts | Arthritis (not osteoarthritis) (ebi-a-GCST90038699) | rs7496663 | -0.0686476523643913 | 0.034437683137646 | 0.046219014842649 |
| Unsalted peanuts | Arthritis (not osteoarthritis) (ebi-a-GCST90038699) | All - MR Egger | -0.0352942403014738 | 0.012182589633986 | 0.0063711231898773 |
| Unsalted peanuts | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | rs117116541 | 0.0929619270983574 | 0.033929907733728 | 0.0061472359413176 |
| Unsalted peanuts | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | All - Inverse variance weighted | -0.0137926500457765 | 0.0060609046668094 | 0.0228654606458981 |
| Unsalted peanuts | Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) | rs117185125 | 13.6902641355794 | 5.97994808896127 | 0.0220583453966198 |
| Unsalted peanuts | Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) | All - Inverse variance weighted | 2.59761181016338 | 1.10328074050754 | 0.0185504797406173 |
| Unsalted peanuts | Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) | rs117185125 | 13.2220469235076 | 5.96976945391623 | 0.0267714770902998 |
| Unsalted peanuts | Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) | All - Inverse variance weighted | 2.59244820316959 | 1.10517898533331 | 0.0189900101951255 |
| Unsalted peanuts | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | rs111785689 | 7.0743115039549 | 3.54496404282067 | 0.0459780554069626 |
| Unsalted peanuts | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | rs146515519 | -26.9368391428457 | 10.1435291279701 | 0.0079174788830111 |
| Unsalted peanuts | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | rs149876304 | 14.0593201555542 | 6.76519776743436 | 0.0376924914224757 |
| Unsalted peanuts | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | rs9563880 | 6.37590800811693 | 2.98797164956033 | 0.0328543844930137 |
| Unsalted peanuts | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | All - Inverse variance weighted | 1.29478295661031 | 0.593910909742512 | 0.0292503265114489 |
| Unsalted peanuts | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | rs56379516 | -75.3676110054186 | 29.1521277487247 | 0.0097288345979024 |
| Unsalted peanuts | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | All - Inverse variance weighted | -6.995254978772 | 3.36211610716883 | 0.037469547407227 |
| Unsalted peanuts | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | rs17322729 | -34.8763859572506 | 16.4009995875488 | 0.0334633718792654 |
| Unsalted peanuts | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | All - Inverse variance weighted | -3.6370821905251 | 1.55040353894114 | 0.018981510405485 |
| Unsalted peanuts | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | rs111557069 | -15.318197186029 | 6.41335725988921 | 0.0169180737986986 |
| Unsalted peanuts | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | rs112322940 | 4.83449941400007 | 2.27740881485954 | 0.0337700265574475 |
| Unsalted peanuts | Collapsed vertebra, not elsewhere classified (finn-b-M13_VERTEBCOLLAPSE) | rs1977495 | 77.9878609122475 | 34.1446235286996 | 0.0223688790793616 |
| Unsalted peanuts | Collapsed vertebra, not elsewhere classified (finn-b-M13_VERTEBCOLLAPSE) | All - Inverse variance weighted | -11.7580363813446 | 4.14809534968491 | 0.0045888451180821 |
| Unsalted peanuts | Villonodular synovitis (pigmented) (finn-b-M13_VILLONODULAR) | rs115700413 | -45.7241594610096 | 21.5044395559718 | 0.0334811143244683 |
| Unsalted peanuts | Villonodular synovitis (pigmented) (finn-b-M13_VILLONODULAR) | rs117116541 | 86.0413296042207 | 42.1615474981083 | 0.0412753252651728 |
| Unsalted peanuts | Osteonecrosis due to drugs (finn-b-OSTEON_DRUGS) | All - Inverse variance weighted | -8.03712313363182 | 3.74931222439708 | 0.0320628664914443 |
| Unsalted peanuts | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | rs6570675 | -36.5564671767295 | 13.3307417900104 | 0.0061016528155596 |
| Unsalted peanuts | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | rs72694839 | 12.6347903151944 | 6.18725846465059 | 0.0411449821923429 |
| Unsalted peanuts | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | All - MR Egger | 11.1062286337438 | 3.43167907376714 | 0.0023324750818155 |
| Unsalted peanuts | Bone morphogenetic protein 6 (prot-a-256) | rs117384765 | -13.8531330079135 | 4.78022272032724 | 0.0037553867521146 |
| Unsalted peanuts | Bone morphogenetic protein 6 (prot-a-256) | rs17322729 | -9.83817356915836 | 4.78766851865331 | 0.0398887950257951 |
| Unsalted peanuts | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | rs113940640 | -0.102376926560019 | 0.0440023729143859 | 0.0199853469477131 |
| Unsalted peanuts | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | rs117607030 | 0.0866203635830523 | 0.0418175487465181 | 0.0383225627517574 |
| Unsalted peanuts | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | rs56379516 | 0.0915082615525336 | 0.0439803084954828 | 0.037464636087583 |
| Unsalted peanuts | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | All - MR Egger | -0.0266245375413122 | 0.0131585448151499 | 0.0494299397664793 |
| Unsalted peanuts | Heel bone mineral density (BMD), manual entry (ukb-b-11364) | rs113940640 | -2.85319455032126 | 1.39321598679422 | 0.0405678622684952 |
| Unsalted peanuts | Heel bone mineral density (BMD), manual entry (ukb-b-11364) | rs7496663 | 3.70181002317189 | 1.54908395417932 | 0.0168632041465159 |
| Unsalted peanuts | Heel bone mineral density (BMD), manual entry (ukb-b-11364) | All - Inverse variance weighted | 0.603616801633554 | 0.215744143653431 | 0.0051446175588522 |
| Unsalted peanuts | Diagnoses - main ICD10: N32.0 Bladder-neck obstruction (ukb-b-123) | rs6570675 | 0.0812493987423162 | 0.024652252188578 | 0.0009813468658208 |
| Unsalted peanuts | Heel bone ultrasound T-score, manual entry (ukb-b-17612) | rs140323162 | 2.68542329464503 | 1.06024153014133 | 0.0113142237794126 |
| Unsalted peanuts | Heel bone ultrasound T-score, manual entry (ukb-b-17612) | rs7496663 | 3.22056209209091 | 1.57037185371057 | 0.0402837292969581 |
| Unsalted peanuts | Heel bone ultrasound T-score, manual entry (ukb-b-17612) | All - Inverse variance weighted | 0.59221099183034 | 0.218806627054998 | 0.0067986422851473 |
| Unsalted peanuts | Diagnoses - main ICD10: M54.56 Low back pain (Lumbar region) (ukb-b-19813) | rs56379516 | -0.0605793695651786 | 0.0238341377656454 | 0.0110312938088153 |
| Unsalted peanuts | Diagnoses - main ICD10: M54.56 Low back pain (Lumbar region) (ukb-b-19813) | rs6570675 | -0.0706372251638857 | 0.0250372534352674 | 0.00478317019882 |
| Unsalted peanuts | Diagnoses - main ICD10: M54.56 Low back pain (Lumbar region) (ukb-b-19813) | All - Inverse variance weighted | -0.0653608430931751 | 0.0172629441391729 | 0.0001529727074581 |
| Unsalted peanuts | Diagnoses - main ICD10: M75.0 Adhesive capsulitis of shoulder (ukb-b-4921) | rs6570675 | 0.0452255722500682 | 0.0210333190013134 | 0.0315404141359968 |
| Unsalted peanuts | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs150206483 | 0.197993785684787 | 0.0920105407371961 | 0.0314083966323138 |
| Unsalted peanuts | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs16946349 | 0.183894200724909 | 0.0888763904511936 | 0.0385366390947203 |
| Unsalted peanuts | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs56379516 | -0.238961863311289 | 0.0876391412335897 | 0.0063979539847204 |
| Unsalted peanuts | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs6570675 | -0.189417668435591 | 0.0910171611213529 | 0.0374228893793622 |
| Unsalted peanuts | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | All - MR Egger | 0.0615969012177821 | 0.0270926211384183 | 0.0281673004193003 |
| Unsalted peanuts | Diagnoses - main ICD10: M47 Spondylosis (ukb-d-M47) | rs112608685 | -0.0906545269597484 | 0.0327781399313739 | 0.0056800627807679 |
| Unsalted peanuts | Diagnoses - main ICD10: M47 Spondylosis (ukb-d-M47) | rs113430016 | 0.0791163086883267 | 0.0390635737691869 | 0.0428343284282177 |
| Unsalted peanuts | Diagnoses - main ICD10: M47 Spondylosis (ukb-d-M47) | rs17322729 | 0.0731235493445261 | 0.0367934751841878 | 0.0468774955411366 |
| Unsalted peanuts | Diagnoses - main ICD10: M47 Spondylosis (ukb-d-M47) | rs1977495 | 0.0928850693622852 | 0.0398669432720509 | 0.0198126593672935 |
| Unsalted peanuts | Diagnoses - main ICD10: M47 Spondylosis (ukb-d-M47) | rs79100208 | 0.109090129246254 | 0.0400564260932556 | 0.0064611534852138 |
| Unsalted peanuts | Diagnoses - main ICD10: M47 Spondylosis (ukb-d-M47) | All - MR Egger | 0.0267400019918878 | 0.0124779853890405 | 0.0380992452589849 |
| Unsalted peanuts | Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) | All - Inverse variance weighted | -2.34182074489241 | 0.963960358009788 | 0.0151248988666787 |
| Unsalted peanuts | Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) | All - Inverse variance weighted | -2.47525844643389 | 0.957528000914458 | 0.0097364673929484 |
| Unsalted peanuts | M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_AFR) | All - MR Egger | 9.13502693172934 | 3.80456391216174 | 0.0320207707301874 |
| Unsalted peanuts | M75 Shoulder lesions (ukb-e-M75_CSA) | rs141446668 | -42.2429626297837 | 19.5713054141031 | 0.0308957255802229 |
| Unsalted peanuts | M75 Shoulder lesions (ukb-e-M75_CSA) | rs34393743 | -54.9345120919887 | 20.1544988735938 | 0.0064171129259258 |
| Unsalted peanuts | M75 Shoulder lesions (ukb-e-M75_CSA) | All - Inverse variance weighted | -5.36063999727063 | 2.40038480299747 | 0.0255329944360622 |