ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
Intake (exposure) | Outcome | SNP | b | se | P-value |
---|---|---|---|---|---|
Mashed potato | Osteoarthritis (self-reported) (ebi-a-GCST005811) | rs264633 | 1.325777975588 | 0.644015486478545 | 0.0395314272000412 |
Mashed potato | Osteoarthritis (self-reported) (ebi-a-GCST005811) | rs4756830 | -1.34784284024927 | 0.631424863696558 | 0.0327932668017106 |
Mashed potato | Osteoarthritis (self-reported) (ebi-a-GCST005811) | All - MR Egger | 1.08832157683668 | 0.375401445841401 | 0.0176215409627539 |
Mashed potato | Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) | rs264633 | -7.18474997723082 | 2.98662890706223 | 0.0161442238345114 |
Mashed potato | Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) | All - Inverse variance weighted | -2.66562728879109 | 1.29561893684766 | 0.039646215647784 |
Mashed potato | Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) | rs264633 | -7.1400708336269 | 2.98147362126177 | 0.0166288582387832 |
Mashed potato | Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) | All - Inverse variance weighted | -2.66509498901888 | 1.29529512985423 | 0.0396362810745518 |
Mashed potato | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | rs4756830 | -5.01809259333076 | 2.143651204918 | 0.0192368505599281 |
Mashed potato | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | All - Inverse variance weighted | -1.61643690815683 | 0.694371089773933 | 0.0199166150899221 |
Mashed potato | Melanocytic naevi of scalp and neck (finn-b-CD2_BENIGN_MELANOCYTIC_SCALPNECK) | rs264633 | -7.91851898949525 | 2.70824347383778 | 0.0034572256668406 |
Mashed potato | Melanocytic naevi of scalp and neck (finn-b-CD2_BENIGN_MELANOCYTIC_SCALPNECK) | All - Inverse variance weighted | -2.94162205291814 | 1.17487819038691 | 0.0122878686611235 |
Mashed potato | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | rs57664184 | -18.5285971723329 | 6.86658684372846 | 0.0069679787573132 |
Mashed potato | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | All - Inverse variance weighted | -5.85790192816334 | 2.09471956102957 | 0.0051657985672253 |
Mashed potato | Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) | All - Inverse variance weighted | 1.08027227820453 | 0.548607364725975 | 0.0489396173467148 |
Mashed potato | Ankylosing spondylitis, strict definition (finn-b-M13_ANKYLOSPON_STRICT) | rs55768233 | 5.71232839518034 | 2.18258982558079 | 0.008864791748922 |
Mashed potato | Ankylosing spondylitis, strict definition (finn-b-M13_ANKYLOSPON_STRICT) | All - Inverse variance weighted | 2.10633995754711 | 0.843509459966752 | 0.0125208414277545 |
Mashed potato | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | rs4756830 | -7.26361152079652 | 3.48121869228418 | 0.0369320888436549 |
Mashed potato | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | rs55768233 | 7.42498261238249 | 2.90733496383584 | 0.0106530175019687 |
Mashed potato | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | All - Inverse variance weighted | -2.45963049732892 | 1.02418883900873 | 0.0163262225989932 |
Mashed potato | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | rs79733344 | 3.04822482117149 | 1.29424124083331 | 0.0185116665955291 |
Mashed potato | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | All - Inverse variance weighted | 0.619561509940249 | 0.302206426010194 | 0.0403520533258209 |
Mashed potato | Fracture at wrist and hand level (finn-b-ST19_FRACT_WRIST_HAND_LEVEL) | rs115597995 | -3.26030580513359 | 1.54578583675143 | 0.0349309882156078 |
Mashed potato | Fracture at wrist and hand level (finn-b-ST19_FRACT_WRIST_HAND_LEVEL) | rs55768233 | -1.88600824162627 | 0.741453959886296 | 0.0109697184903318 |
Mashed potato | Fracture at wrist and hand level (finn-b-ST19_FRACT_WRIST_HAND_LEVEL) | All - Inverse variance weighted | -0.625935862450019 | 0.29912338220986 | 0.0363877819914597 |
Mashed potato | Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) | All - MR Egger | -0.975473762714602 | 0.403726259673204 | 0.0388535149500367 |
Mashed potato | Injury of nerves and spinal cord at neck level (finn-b-ST19_INJURY_NERVES_SPINAL_CORD_NECK_LEVEL) | All - Inverse variance weighted | -4.26271553834336 | 1.31440475484706 | 0.0011824634141661 |
Mashed potato | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | All - MR Egger | -6.43840984715185 | 2.83757028875025 | 0.049444893286269 |
Mashed potato | Rheumatoid arthritis (ieu-a-833) | rs264633 | 1.24707566412969 | 0.516331086201534 | 0.0157238268329056 |
Mashed potato | Rheumatoid arthritis (ieu-a-833) | rs58215605 | 1.65057087185789 | 0.826234434115117 | 0.0457488866260935 |
Mashed potato | Fracture resulting from simple fall (ukb-a-332) | rs55768233 | -0.34049863300953 | 0.1685723773938 | 0.0433941995558898 |
Mashed potato | Fracture resulting from simple fall (ukb-a-332) | rs58215605 | -0.35442704497536 | 0.168779432621129 | 0.035733930148549 |
Mashed potato | Fracture resulting from simple fall (ukb-a-332) | All - Inverse variance weighted | -0.109731672659014 | 0.0500060093047882 | 0.0282088408944103 |
Mashed potato | Diagnoses - main ICD10: T84.0 Mechanical complication of internal joint prosthesis (ukb-b-14753) | All - Inverse variance weighted | -0.0072826040173549 | 0.0033353297314922 | 0.0290009598436288 |
Mashed potato | Non-cancer illness code, self-reported: osteopenia (ukb-b-19381) | All - Inverse variance weighted | 0.0075332277145112 | 0.0032865813875193 | 0.0218989164750142 |
Mashed potato | Diagnoses - main ICD10: S82.80 Fractures of other parts of lower leg (closed) (ukb-b-5946) | All - Inverse variance weighted | -0.0074757091691953 | 0.0037353023351763 | 0.0453529020818451 |
Mashed potato | Ankle spacing width (ukb-e-3143_AFR) | rs264633 | 1.51943456825341 | 0.581344395431042 | 0.0089579042831002 |
Mashed potato | Ankle spacing width (ukb-e-3143_AFR) | rs57664184 | 4.8317066386077 | 1.27444577482675 | 0.0001499079863696 |
Mashed potato | Ankle spacing width (ukb-e-3143_AFR) | All - Inverse variance weighted | 1.63501433163665 | 0.649549645795127 | 0.0118308221252686 |