ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Other vegetarian alternative (ukb-b-16150)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Other vegetarian alternative (👉 📊) Total body bone mineral density (age 30-45) (ebi-a-GCST005346) MR Egger 30 1.797900049 0.83546388 0.040167849
Other vegetarian alternative (👉 📊) Frozen shoulder (ebi-a-GCST90000512) MR Egger 20 -3.26129099 1.473247961 0.040002322
Other vegetarian alternative (👉 📊) Frozen shoulder (ebi-a-GCST90000513) MR Egger 18 3.160018601 1.445031291 0.043954843
Other vegetarian alternative (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) Inverse variance weighted 28 -3.113053703 1.249292461 0.012707847
Other vegetarian alternative (👉 📊) Compression fracture (ebi-a-GCST90018828) MR Egger 28 -3.137928311 1.46654578 0.041936761
Other vegetarian alternative (👉 📊) Benign neoplasm: Short bones of lower limb (finn-b-CD2_BENIGN_BONE_SHORT_LOWER) Simple mode 29 -23.35637025 10.06649879 0.027838375
Other vegetarian alternative (👉 📊) Benign neoplasm: Short bones of lower limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_LOWER_EXALLC) Simple mode 29 -22.99394994 10.88790785 0.043749022
Other vegetarian alternative (👉 📊) Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) Weighted median 29 -11.14393163 5.566188197 0.045276562
Other vegetarian alternative (👉 📊) Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) Inverse variance weighted 29 -7.663142879 3.749596016 0.040980728
Other vegetarian alternative (👉 📊) Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) Inverse variance weighted 29 -1.745785227 0.879189183 0.047069265
Other vegetarian alternative (👉 📊) Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) Weighted median 29 2.235812862 0.963900016 0.020365313
Other vegetarian alternative (👉 📊) Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) Weighted mode 29 3.059008227 1.28450449 0.024280705
Other vegetarian alternative (👉 📊) Bicipital tendinitis (finn-b-M13_BICIPITALTEND) MR Egger 29 6.93791115 2.929254526 0.025275766
Other vegetarian alternative (👉 📊) Bicipital tendinitis (finn-b-M13_BICIPITALTEND) Inverse variance weighted 29 3.789948589 1.768125828 0.032074292
Other vegetarian alternative (👉 📊) Calcific tendinitis (finn-b-M13_CALCTENDINITIS) MR Egger 29 -14.82257955 6.860168761 0.039757934
Other vegetarian alternative (👉 📊) Chondromalacia (finn-b-M13_CHONDROMALACIA) Inverse variance weighted 29 -4.683000675 2.24220032 0.036746112
Other vegetarian alternative (👉 📊) Osteonecrosis (finn-b-M13_OSTEONECROSIS) MR Egger 29 6.931079966 3.321708064 0.046498692
Other vegetarian alternative (👉 📊) Other joint disorders (finn-b-M13_OTHERJOINT) Weighted median 29 0.869806134 0.408019994 0.033025487
Other vegetarian alternative (👉 📊) Spinal osteochondrosis (finn-b-M13_SPINALOSTEOCHON) Simple mode 29 -24.06952397 8.880285782 0.011343571
Other vegetarian alternative (👉 📊) Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) MR Egger 29 18.97532173 7.69233804 0.020268366
Other vegetarian alternative (👉 📊) Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) Weighted median 29 15.06633204 6.749660077 0.025604284
Other vegetarian alternative (👉 📊) Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) Inverse variance weighted 29 12.51973552 4.643777756 0.007017265
Other vegetarian alternative (👉 📊) Injury of muscle and tendon at wrist and hand level (finn-b-ST19_INJURY_MUSCLE_TENDON_WRIST_HAND_LEVEL) Simple mode 29 -5.588454774 2.489945501 0.032892842
Other vegetarian alternative (👉 📊) Femoral neck bone mineral density (ieu-a-980) MR Egger 28 1.234813849 0.495688738 0.01944458
Other vegetarian alternative (👉 📊) Lumbar spine bone mineral density (ieu-a-982) Inverse variance weighted 28 0.683883349 0.33519447 0.041324591
Other vegetarian alternative (👉 📊) Psoriatic arthritis (ieu-b-5116) Inverse variance weighted 22 -3.242195896 1.280060794 0.011314089
Other vegetarian alternative (👉 📊) Fracture resulting from simple fall (ukb-a-332) MR Egger 28 -0.529383929 0.242536512 0.038281214
Other vegetarian alternative (👉 📊) Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) Inverse variance weighted 3 0.035102811 0.015991716 0.028159141
Other vegetarian alternative (👉 📊) Operative procedures - secondary OPCS: Z81.5 Elbow joint (ukb-b-7443) Inverse variance weighted 2 -0.032104451 0.015089008 0.03336434
Other vegetarian alternative (👉 📊) Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) MR Egger 26 0.0318503 0.012448645 0.017242624
Other vegetarian alternative (👉 📊) Ankle spacing width (ukb-e-3143_AFR) Inverse variance weighted 9 -1.36084361 0.665742819 0.04094386
Other vegetarian alternative (👉 📊) Heel bone mineral density (BMD) (ukb-e-3148_CSA) MR Egger 16 -5.468478779 2.548319232 0.049895012
Other vegetarian alternative (👉 📊) Spondylosis and allied disorders (ukb-e-721_CSA) MR Egger 16 -24.31170916 9.608687448 0.024022603

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Other vegetarian alternative Total body bone mineral density (age 30-45) (ebi-a-GCST005346) rs4076876 4.011752036999 1.66196709678624 0.0157846266647966
Other vegetarian alternative Total body bone mineral density (age 30-45) (ebi-a-GCST005346) All - MR Egger 1.79790004894787 0.835463880425061 0.0401678491066921
Other vegetarian alternative Frozen shoulder (ebi-a-GCST90000512) rs10830644 6.6150238166836 2.622379675481 0.0116514969673736
Other vegetarian alternative Frozen shoulder (ebi-a-GCST90000512) rs117334173 -6.33232297070893 2.94103542609245 0.0313113654263188
Other vegetarian alternative Frozen shoulder (ebi-a-GCST90000512) rs148010405 -8.32855439555646 2.71638700671765 0.0021691344525816
Other vegetarian alternative Frozen shoulder (ebi-a-GCST90000512) rs148271528 -6.0203298364774 2.75492877246733 0.0288672832258214
Other vegetarian alternative Frozen shoulder (ebi-a-GCST90000512) All - MR Egger -3.26129098987876 1.47324796070723 0.0400023215001097
Other vegetarian alternative Frozen shoulder (ebi-a-GCST90000513) rs10830644 -6.69037955448478 2.38433739441745 0.0050165339353528
Other vegetarian alternative Frozen shoulder (ebi-a-GCST90000513) rs148010405 9.10227702329369 2.47768051880071 0.0002390550460103
Other vegetarian alternative Frozen shoulder (ebi-a-GCST90000513) rs148271528 6.2604465386443 2.28951574582055 0.0062494515603487
Other vegetarian alternative Frozen shoulder (ebi-a-GCST90000513) All - MR Egger 3.16001860148657 1.44503129091822 0.0439548428028829
Other vegetarian alternative Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) rs145564253 -7.06483093743673 3.38658837821421 0.0369677226508922
Other vegetarian alternative Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) rs4652232 -21.2830098664594 8.34112697257215 0.0107237284656167
Other vegetarian alternative Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) All - Inverse variance weighted -3.1130537030492 1.24929246125981 0.0127078466228882
Other vegetarian alternative Compression fracture (ebi-a-GCST90018828) rs11072550 -3.71920883387938 1.65028515956801 0.0242165286492764
Other vegetarian alternative Compression fracture (ebi-a-GCST90018828) rs75322691 14.2980647735586 7.19115071711999 0.0467800608946902
Other vegetarian alternative Compression fracture (ebi-a-GCST90018828) All - MR Egger -3.13792831057664 1.46654577982403 0.0419367606732236
Other vegetarian alternative Benign neoplasm: Short bones of lower limb (finn-b-CD2_BENIGN_BONE_SHORT_LOWER) rs117518847 96.6663499470374 40.5788227179471 0.0172101486054745
Other vegetarian alternative Benign neoplasm: Short bones of lower limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_LOWER_EXALLC) rs117518847 99.0206325242906 41.2122619764009 0.0162746073580263
Other vegetarian alternative Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) rs112076774 -43.7384431549456 21.6543493130653 0.0433994008380244
Other vegetarian alternative Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) rs116688995 64.3881266514724 32.688937518728 0.0488702147104426
Other vegetarian alternative Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) rs117334173 -56.3523346256262 28.3481582802522 0.0468265329336096
Other vegetarian alternative Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) All - Inverse variance weighted -7.66314287939749 3.74959601550825 0.0409807282809103
Other vegetarian alternative Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) rs148010405 -10.4807049175561 5.34504318492453 0.0498992089340533
Other vegetarian alternative Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) rs148271528 -7.51320043730083 3.67186487537259 0.040741236636499
Other vegetarian alternative Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) All - Inverse variance weighted -1.74578522670257 0.879189183098011 0.0470692652647182
Other vegetarian alternative Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs145564253 5.61247216035635 1.87487345616522 0.0027577896467481
Other vegetarian alternative Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs146608609 -6.4581990578729 2.58674014508238 0.0125370681172358
Other vegetarian alternative Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs7034934 6.70531777238979 3.12496074169922 0.0318946345606387
Other vegetarian alternative Bicipital tendinitis (finn-b-M13_BICIPITALTEND) rs11586844 -29.5569271588699 14.6604157532013 0.0437890710896251
Other vegetarian alternative Bicipital tendinitis (finn-b-M13_BICIPITALTEND) rs59102815 36.4420033923445 16.8515812583983 0.0305775602965632
Other vegetarian alternative Bicipital tendinitis (finn-b-M13_BICIPITALTEND) All - Inverse variance weighted 3.78994858890712 1.7681258276538 0.0320742922675797
Other vegetarian alternative Bicipital tendinitis (finn-b-M13_BICIPITALTEND) All - MR Egger 6.93791114996672 2.92925452563073 0.025275766054668
Other vegetarian alternative Calcific tendinitis (finn-b-M13_CALCTENDINITIS) rs142607413 130.624214190716 53.2933130809538 0.0142442845111568
Other vegetarian alternative Calcific tendinitis (finn-b-M13_CALCTENDINITIS) All - MR Egger -14.8225795489996 6.86016876060969 0.0397579343575407
Other vegetarian alternative Chondromalacia (finn-b-M13_CHONDROMALACIA) All - Inverse variance weighted -4.68300067450583 2.24220032049443 0.036746112486126
Other vegetarian alternative Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs11072550 72.7551268049994 31.9894430287586 0.0229450693597395
Other vegetarian alternative Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs114012672 23.3363138785021 9.15840242778952 0.0108318583703786
Other vegetarian alternative Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs116688995 42.2005103106357 17.4931217027304 0.015847626916836
Other vegetarian alternative Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs7719244 9.5268720988759 4.50757787595772 0.034555979540612
Other vegetarian alternative Osteonecrosis (finn-b-M13_OSTEONECROSIS) All - MR Egger 6.93107996610117 3.32170806444196 0.0464986923451496
Other vegetarian alternative Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) rs148271528 50.5620777770763 19.8912064651405 0.0110241879739277
Other vegetarian alternative Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) rs7719244 26.542139701359 10.902634080868 0.0149136005256412
Other vegetarian alternative Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) rs77224874 73.183198532728 30.7585916594005 0.01734665232246
Other vegetarian alternative Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) All - Inverse variance weighted 12.5197355172788 4.64377775649145 0.0070172645238923
Other vegetarian alternative Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) All - MR Egger 18.9753217260167 7.6923380395325 0.0202683656866076
Other vegetarian alternative Injury of muscle and tendon at wrist and hand level (finn-b-ST19_INJURY_MUSCLE_TENDON_WRIST_HAND_LEVEL) rs16997270 -20.6363040877422 9.6685307189684 0.0328118101249131
Other vegetarian alternative Femoral neck bone mineral density (ieu-a-980) rs142607413 3.38546625289796 1.4334251473506 0.0181863568513472
Other vegetarian alternative Femoral neck bone mineral density (ieu-a-980) All - MR Egger 1.23481384905242 0.49568873816552 0.019444580026669
Other vegetarian alternative Lumbar spine bone mineral density (ieu-a-982) rs116688995 3.38530269048116 1.53792370765194 0.0277207168846127
Other vegetarian alternative Lumbar spine bone mineral density (ieu-a-982) rs148054266 4.06713683630896 1.84814791282801 0.0277604226170196
Other vegetarian alternative Lumbar spine bone mineral density (ieu-a-982) All - Inverse variance weighted 0.683883349220835 0.335194469943276 0.0413245909927076
Other vegetarian alternative Psoriatic arthritis (ieu-b-5116) rs112076774 -18.4922651953487 4.53237229723519 4.5027741186901e-05
Other vegetarian alternative Psoriatic arthritis (ieu-b-5116) rs144319235 -10.0012257781137 4.36514908526308 0.0219545482381944
Other vegetarian alternative Psoriatic arthritis (ieu-b-5116) All - Inverse variance weighted -3.24219589594568 1.28006079362583 0.0113140890810977
Other vegetarian alternative Fracture resulting from simple fall (ukb-a-332) rs189686440 -1.89449256384447 0.750465811429743 0.0115888649381436
Other vegetarian alternative Fracture resulting from simple fall (ukb-a-332) rs73175034 -1.88496510890252 0.757417408136376 0.0128220430548476
Other vegetarian alternative Fracture resulting from simple fall (ukb-a-332) All - MR Egger -0.529383928603859 0.242536512226395 0.038281214391685
Other vegetarian alternative Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) All - Inverse variance weighted 0.0351028112480364 0.0159917164096213 0.0281591405380456
Other vegetarian alternative Operative procedures - secondary OPCS: Z81.5 Elbow joint (ukb-b-7443) rs10830644 -0.0400278647191019 0.0203383979743808 0.0490573039962592
Other vegetarian alternative Operative procedures - secondary OPCS: Z81.5 Elbow joint (ukb-b-7443) All - Inverse variance weighted -0.0321044512275691 0.0150890084423171 0.0333643404675265
Other vegetarian alternative Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) rs142455309 0.084318970808015 0.0337605235911154 0.0125050909093474
Other vegetarian alternative Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) rs142607413 0.0693499858281794 0.0348386592730946 0.0465244043963376
Other vegetarian alternative Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) rs148271528 0.0889937096468696 0.033487407663398 0.0078716147993363
Other vegetarian alternative Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) All - MR Egger 0.0318503001490124 0.0124486453852027 0.0172426236045492
Other vegetarian alternative Ankle spacing width (ukb-e-3143_AFR) rs11586844 -35.1332816171428 17.8645710366848 0.0492240722378725
Other vegetarian alternative Ankle spacing width (ukb-e-3143_AFR) All - Inverse variance weighted -1.36084360956449 0.665742818824098 0.0409438600129424
Other vegetarian alternative Heel bone mineral density (BMD) (ukb-e-3148_CSA) rs116688995 -11.2731433137502 4.92150114865294 0.021987114347771
Other vegetarian alternative Heel bone mineral density (BMD) (ukb-e-3148_CSA) All - MR Egger -5.46847877895915 2.54831923189934 0.0498950119480635
Other vegetarian alternative Spondylosis and allied disorders (ukb-e-721_CSA) rs10830644 43.1315958512529 18.7366214650864 0.0213354935124398
Other vegetarian alternative Spondylosis and allied disorders (ukb-e-721_CSA) rs145564253 -64.7499493824661 22.9439157724236 0.0047710786205166
Other vegetarian alternative Spondylosis and allied disorders (ukb-e-721_CSA) rs59102815 -39.1881870048242 19.069087811791 0.0398728684277961
Other vegetarian alternative Spondylosis and allied disorders (ukb-e-721_CSA) All - MR Egger -24.3117091585783 9.60868744820308 0.0240226027578671