ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Carrot | Total body bone mineral density (ebi-a-GCST005348) | rs28656094 | -0.334723329449521 | 0.163528954845567 | 0.0406703593113469 |
| Carrot | Total body bone mineral density (ebi-a-GCST005348) | All - Inverse variance weighted | -0.151074481728833 | 0.0749941756922875 | 0.0439588623456181 |
| Carrot | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | rs16898247 | -1.20196542128705 | 0.47407849986212 | 0.0112327925606853 |
| Carrot | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | rs28656094 | -1.05916681997506 | 0.444727213262198 | 0.0172371374687205 |
| Carrot | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | All - Inverse variance weighted | -0.594617464700619 | 0.251524686638695 | 0.0180762700947763 |
| Carrot | Osteoporosis (ebi-a-GCST90038656) | All - Inverse variance weighted | 0.00733234328366 | 0.0033369753692031 | 0.0279988714263902 |
| Carrot | Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) | rs28656094 | -8.30675987817093 | 4.05500705218618 | 0.0405091509258777 |
| Carrot | Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) | All - Inverse variance weighted | -5.70155877852397 | 2.01064677185099 | 0.0045727673125289 |
| Carrot | Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) | rs28656094 | -8.27865333905685 | 4.05500705218618 | 0.0411924263917443 |
| Carrot | Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) | All - Inverse variance weighted | -5.68881834296369 | 2.01167632540791 | 0.0046854522803249 |
| Carrot | Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) | rs116391685 | 9.21055204646342 | 3.63924360052408 | 0.0113771133452719 |
| Carrot | Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) | All - Inverse variance weighted | 6.23630959509159 | 2.03619880878304 | 0.0021933418306671 |
| Carrot | Ankylosing spondylitis, strict definition (finn-b-M13_ANKYLOSPON_STRICT) | All - Inverse variance weighted | -1.75696088126317 | 0.779069943547502 | 0.0241205891242476 |
| Carrot | Other intervertebral disc disorders (finn-b-M13_INTERVERTEB) | All - Inverse variance weighted | 0.335300410284545 | 0.158486407392369 | 0.0343753150349935 |
| Carrot | Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) | All - Inverse variance weighted | -0.31235010005644 | 0.155735215060908 | 0.0448937637430614 |
| Carrot | Postmenopausal osteoporosis with pathological fracture (finn-b-OSTPOPATFRCTURE_POSTEMENO) | rs16898247 | -4.80157768511477 | 2.28045692702371 | 0.0352449237668473 |
| Carrot | Postmenopausal osteoporosis with pathological fracture (finn-b-OSTPOPATFRCTURE_POSTEMENO) | All - Inverse variance weighted | -2.06731260700796 | 0.789962467907096 | 0.0088712648404924 |
| Carrot | Burn and corrosion of wrist and hand (finn-b-ST19_BURN_CORROSION_WRIST_HAND) | rs4375234 | -4.57115753055189 | 2.29487918751511 | 0.0463826202760451 |
| Carrot | Burn and corrosion of wrist and hand (finn-b-ST19_BURN_CORROSION_WRIST_HAND) | All - Inverse variance weighted | -2.65466212418999 | 0.921055663915807 | 0.003949151238672 |
| Carrot | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | rs116391685 | -1.26033987132605 | 0.564170756986135 | 0.02548512574919 |
| Carrot | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | All - Inverse variance weighted | -0.670106684209285 | 0.316226685873372 | 0.0340844979065474 |
| Carrot | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | All - Inverse variance weighted | -0.405638900686451 | 0.198646068376792 | 0.0411497191828464 |
| Carrot | Bone morphogenetic protein 6 (prot-a-255) | All - Inverse variance weighted | 0.668747790162189 | 0.332532361114506 | 0.0443174489778008 |
| Carrot | Bone morphogenetic protein 7 (prot-a-257) | All - Inverse variance weighted | -0.804226463421472 | 0.332532361114506 | 0.0155850387151143 |
| Carrot | Bone morphogenetic protein receptor type-1A (prot-a-259) | rs11681135 | 1.72078616673953 | 0.776679161744598 | 0.0267210433446375 |
| Carrot | Bone morphogenetic protein receptor type-1A (prot-a-259) | All - Inverse variance weighted | 0.750651556266628 | 0.338624117565622 | 0.0266388587486513 |
| Carrot | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | All - Inverse variance weighted | -0.0036156713919701 | 0.0016254306814359 | 0.0261189226720259 |
| Carrot | Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) | rs28656094 | 0.0069237137425645 | 0.0031985752539809 | 0.0304164679899843 |
| Carrot | Fractured bone site(s): Other bones (ukb-b-17738) | rs16898247 | -0.0303460378209896 | 0.0143737308743284 | 0.0347538265863755 |
| Carrot | Fractured heel (ukb-b-18389) | All - Inverse variance weighted | -0.0056074832362484 | 0.0019798912889135 | 0.0046226358178759 |
| Carrot | Diagnoses - main ICD10: M13 Other arthritis (ukb-d-M13) | rs11681135 | -0.0119767182282414 | 0.0042117636662977 | 0.004460212145755 |
| Carrot | Impingement syndrome of shoulder (ukb-d-M13_IMPINGEMENT) | rs116391685 | -0.0143726655846061 | 0.0065539042180808 | 0.0283078888030003 |
| Carrot | Impingement syndrome of shoulder (ukb-d-M13_IMPINGEMENT) | rs11681135 | 0.0139609009478276 | 0.0070537815438707 | 0.0477925912141912 |
| Carrot | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | All - Inverse variance weighted | -0.005858112965729 | 0.0028141899309683 | 0.0373759288357459 |
| Carrot | Other arthritis (FG) (ukb-d-RHEU_ARTHRITIS_OTH) | rs11681135 | -0.0119767182282414 | 0.0042117636662977 | 0.004460212145755 |