ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Garlic | Osteoarthritis (hip) (ebi-a-GCST007091) | rs4584661 | -1.88878142532583 | 0.714506131291019 | 0.0082059034893942 |
| Garlic | Osteoarthritis (hip) (ebi-a-GCST007091) | rs62081074 | -1.91013842703581 | 0.672801794138118 | 0.0045243747072319 |
| Garlic | Osteoarthritis (hip) (ebi-a-GCST007091) | All - Inverse variance weighted | -0.433189910264779 | 0.17680720243544 | 0.0142828696533165 |
| Garlic | Ultradistal forearm bone mineral density (ebi-a-GCST90013422) | rs17640594 | -1.10381290646945 | 0.516458802986317 | 0.0325758799473833 |
| Garlic | Ultradistal forearm bone mineral density (ebi-a-GCST90013422) | rs74679312 | -1.67180715567649 | 0.516960477817017 | 0.0012210503661597 |
| Garlic | Ultradistal forearm bone mineral density (ebi-a-GCST90013422) | All - Inverse variance weighted | -0.503511254422211 | 0.159040388778104 | 0.0015458626443423 |
| Garlic | Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016610) | rs72780997 | 0.628001599751444 | 0.294169170409887 | 0.0327747794725053 |
| Garlic | Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016610) | rs78818759 | -0.279540024246419 | 0.132413695695672 | 0.0347627626222285 |
| Garlic | Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016610) | All - MR Egger | -0.515963359128209 | 0.222105821566431 | 0.045259101467641 |
| Garlic | Cervical spondylosis (ebi-a-GCST90038693) | rs143374250 | -0.0243608093325428 | 0.0098946665219243 | 0.0138159202448042 |
| Garlic | Cervical spondylosis (ebi-a-GCST90038693) | rs147518355 | -0.0207101262060787 | 0.0099524042125582 | 0.0374415122072028 |
| Garlic | Cervical spondylosis (ebi-a-GCST90038693) | rs6835673 | 0.0204817618216733 | 0.009325791766988 | 0.0280741183905595 |
| Garlic | Cervical spondylosis (ebi-a-GCST90038693) | rs74679312 | -0.0271374881800112 | 0.0091852409347922 | 0.0031320998552801 |
| Garlic | Cervical spondylosis (ebi-a-GCST90038693) | All - Inverse variance weighted | -0.0058480093772886 | 0.0029069256622439 | 0.0442462362084709 |
| Garlic | Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) | rs56269735 | -13.6066563542534 | 6.47831087959596 | 0.0356989309960786 |
| Garlic | Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) | rs77374784 | -12.6725272348173 | 5.05939683817742 | 0.0122537766496887 |
| Garlic | Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) | All - Inverse variance weighted | -3.81541949593704 | 1.14927563550125 | 0.0009006673158309 |
| Garlic | Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) | All - Inverse variance weighted | 0.947196992281224 | 0.419415082306268 | 0.0239222222992607 |
| Garlic | Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) | All - MR Egger | 1.45108832236924 | 0.673297668467009 | 0.0457735298135225 |
| Garlic | Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) | All - MR Egger | 1.41312937977189 | 0.668991567209233 | 0.0497570169410911 |
| Garlic | Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) | rs6835673 | 4.28173160341954 | 1.86427130143196 | 0.0216340612988028 |
| Garlic | Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) | All - MR Egger | -2.20400087000014 | 0.938761829225837 | 0.0312493630798801 |
| Garlic | Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) | rs138637793 | 2.80958672509856 | 1.42502520183459 | 0.0486547230262578 |
| Garlic | Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) | rs56317696 | 2.71572637400851 | 1.17019103920692 | 0.0203000857435503 |
| Garlic | Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) | All - MR Egger | -1.29679455445101 | 0.598023013177618 | 0.0446007235158909 |
| Garlic | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | rs143374250 | -7.55722194851068 | 3.83288936394078 | 0.0486464269139645 |
| Garlic | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | All - Inverse variance weighted | -1.84196540775268 | 0.820575996654136 | 0.0247859522921487 |
| Garlic | Shoulder region (finn-b-Z21_SHOUL_REGION) | rs62081074 | -20.4160544428118 | 6.99095197587194 | 0.0034963399939478 |
| Garlic | Shoulder region (finn-b-Z21_SHOUL_REGION) | All - Inverse variance weighted | -3.99085260561465 | 1.68284994859022 | 0.0177167887330438 |
| Garlic | Rheumatoid arthritis (ieu-a-834) | All - Inverse variance weighted | -1.53955362088876 | 0.766522874728432 | 0.0445912348673118 |
| Garlic | Osteomodulin (prot-a-2147) | rs17640594 | -3.31716916157144 | 1.68993983035729 | 0.0496587391197587 |
| Garlic | Osteomodulin (prot-a-2147) | All - Inverse variance weighted | -0.793429648506196 | 0.337490781395084 | 0.0187247005807144 |
| Garlic | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | rs141575721 | -0.455226289940713 | 0.227010732384996 | 0.0449301996638343 |
| Garlic | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | rs62081074 | -0.521931791818112 | 0.239037584100224 | 0.0290010933814615 |
| Garlic | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | rs74679312 | -0.782196202165229 | 0.220807522337367 | 0.0003964517488389 |
| Garlic | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | All - Inverse variance weighted | -0.131675283430879 | 0.0661509482561961 | 0.0465328547951638 |
| Garlic | Pain type(s) experienced in last month: Knee pain (ukb-a-476) | rs143374250 | -0.143571518041302 | 0.0589961003064641 | 0.0149504795055899 |
| Garlic | Pain type(s) experienced in last month: Knee pain (ukb-a-476) | All - MR Egger | -0.088954557432726 | 0.0368195397733978 | 0.0280143108210188 |
| Garlic | Heel bone mineral density (BMD) T-score automated (ukb-a-500) | rs74679312 | -0.988300623323491 | 0.166079526814489 | 2.66888252773681e-09 |
| Garlic | Heel bone mineral density (BMD) T-score automated (ukb-a-500) | All - Inverse variance weighted | -0.130546100097086 | 0.0658915538297033 | 0.0475658658787039 |
| Garlic | Fractured heel (ukb-b-18389) | rs141575721 | 0.0199552654235232 | 0.008153286242589 | 0.0143846359280269 |
| Garlic | Fractured heel (ukb-b-18389) | rs149467747 | 0.020506565003562 | 0.0088997206923638 | 0.0212124999409 |
| Garlic | Fractured heel (ukb-b-18389) | rs77374784 | 0.0199241691352758 | 0.0089707852880911 | 0.0263505460569224 |
| Garlic | Fractured heel (ukb-b-18389) | All - MR Egger | 0.0125635590706866 | 0.0050131810302188 | 0.0226627533570256 |
| Garlic | Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) | rs56317696 | 0.0239491187688707 | 0.0079416229224969 | 0.002564329438672 |
| Garlic | Operative procedures - main OPCS: W37.1 Primary total prosthetic replacement of hip joint using cement (ukb-b-898) | All - Inverse variance weighted | -0.0163362587620173 | 0.0073007023603336 | 0.0252452995500467 |
| Garlic | Pain in joint (ukb-e-745_CSA) | rs4584661 | -4.80686588616364 | 2.20564936181141 | 0.0293062176671348 |
| Garlic | Pain in joint (ukb-e-745_CSA) | rs78818759 | -12.6602205717918 | 5.52606490036605 | 0.0219633520676223 |