ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Boiled/baked potatoes | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs16841871 | 0.590934380625102 | 0.218244275770049 | 0.006775651469975 |
| Boiled/baked potatoes | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs9962730 | 0.599129461808212 | 0.199647825004425 | 0.0026915503992923 |
| Boiled/baked potatoes | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | All - Inverse variance weighted | 0.21554777191578 | 0.102856013331858 | 0.0361153497599513 |
| Boiled/baked potatoes | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs16841871 | 0.589670581423159 | 0.217237767959417 | 0.0066395588234899 |
| Boiled/baked potatoes | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs9962730 | 0.594758772127179 | 0.197122004337692 | 0.0025511177511065 |
| Boiled/baked potatoes | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | All - Inverse variance weighted | 0.216423537582943 | 0.10269631827087 | 0.0350818114028743 |
| Boiled/baked potatoes | Bone mineral density (ebi-a-GCST90014022) | rs9962730 | -0.425431294378099 | 0.0551111871057155 | 1.16778849370455e-14 |
| Boiled/baked potatoes | Bone mineral density (ebi-a-GCST90014022) | All - Inverse variance weighted | -0.0912087847587182 | 0.0454271399711814 | 0.0446641437119914 |
| Boiled/baked potatoes | Neck circumference (ebi-a-GCST90017135) | rs145471075 | 3.49963603785206 | 1.34036060249734 | 0.0090286854455515 |
| Boiled/baked potatoes | Neck circumference (ebi-a-GCST90017135) | All - MR Egger | 3.07421765238255 | 1.03437043560344 | 0.0248908434912686 |
| Boiled/baked potatoes | Neck circumference (BMI adjusted) (ebi-a-GCST90017138) | rs145471075 | 2.19917128618624 | 1.0715885547903 | 0.0401450394179012 |
| Boiled/baked potatoes | Neck circumference (BMI adjusted) (ebi-a-GCST90017138) | All - MR Egger | 2.31690381260264 | 0.80986408431983 | 0.0287694513395957 |
| Boiled/baked potatoes | Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) | rs1614617 | 1.03211912703207 | 0.464847545762534 | 0.0263957655841366 |
| Boiled/baked potatoes | Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) | rs9962730 | 1.06942407089097 | 0.428969543162435 | 0.0126666351544814 |
| Boiled/baked potatoes | Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) | All - Inverse variance weighted | 0.346388184463534 | 0.170240409798933 | 0.0418810548148372 |
| Boiled/baked potatoes | Bone disorder (ebi-a-GCST90038652) | rs9962730 | 0.0236948676643958 | 0.007947440731708 | 0.0028689036830523 |
| Boiled/baked potatoes | Bone disorder (ebi-a-GCST90038652) | All - Inverse variance weighted | 0.0086567827709987 | 0.0032790587129822 | 0.008290097154826 |
| Boiled/baked potatoes | Osteoporosis (ebi-a-GCST90038656) | rs9962730 | 0.0235759261092462 | 0.0067781837489538 | 0.0005047799655386 |
| Boiled/baked potatoes | Osteoporosis (ebi-a-GCST90038656) | All - Inverse variance weighted | 0.0074921229488439 | 0.0028386344948442 | 0.0083067504859441 |
| Boiled/baked potatoes | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs117282450 | -4.39374499487648 | 1.9503836184998 | 0.0242743245275826 |
| Boiled/baked potatoes | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | All - Inverse variance weighted | -2.20201077271724 | 0.879778380194596 | 0.0123175016441086 |
| Boiled/baked potatoes | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs117282450 | -4.40623089442096 | 1.9409115567764 | 0.0231962797354933 |
| Boiled/baked potatoes | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | All - Inverse variance weighted | -2.21295092382037 | 0.879672852909895 | 0.0118812374272459 |
| Boiled/baked potatoes | Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) | rs117282450 | 2.17383816551997 | 0.541629711274337 | 5.98215760547398e-05 |
| Boiled/baked potatoes | Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) | rs16841871 | -1.5935954080284 | 0.798056468159561 | 0.0458419771695555 |
| Boiled/baked potatoes | Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) | rs9962730 | 1.56588882189365 | 0.604457083547068 | 0.0095816932178006 |
| Boiled/baked potatoes | Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) | All - MR Egger | 1.92635120348869 | 0.625179891653454 | 0.0177835032725324 |
| Boiled/baked potatoes | Cervical disc disorders (finn-b-M13_CERVICDISC) | rs145471075 | 0.912705078671818 | 0.42485581499524 | 0.031692298279652 |
| Boiled/baked potatoes | Cervical disc disorders (finn-b-M13_CERVICDISC) | rs79385065 | 1.13013762234645 | 0.522816336385417 | 0.030646390635198 |
| Boiled/baked potatoes | Cervical disc disorders (finn-b-M13_CERVICDISC) | All - Inverse variance weighted | 0.40471008989918 | 0.155658917084502 | 0.0093229161239609 |
| Boiled/baked potatoes | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | rs61911616 | 0.66154746689665 | 0.26323354703741 | 0.0119655767588397 |
| Boiled/baked potatoes | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | All - Inverse variance weighted | 0.266848813345226 | 0.10192365219506 | 0.0088414534284593 |
| Boiled/baked potatoes | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | rs79385065 | 4.86228479096633 | 1.7309585275709 | 0.0049693659115077 |
| Boiled/baked potatoes | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | rs9962730 | -3.11377892169656 | 1.30940703210072 | 0.0174065014815246 |
| Boiled/baked potatoes | Other joint disorders (finn-b-M13_OTHERJOINT) | rs61911616 | 0.45373150870922 | 0.192229761323372 | 0.0182571903419345 |
| Boiled/baked potatoes | Other joint disorders (finn-b-M13_OTHERJOINT) | All - Inverse variance weighted | 0.188742562815837 | 0.0780766548802212 | 0.0156317970175161 |
| Boiled/baked potatoes | Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) | All - Inverse variance weighted | 0.238878664416339 | 0.0997172589482437 | 0.0165950035801743 |
| Boiled/baked potatoes | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | rs111760027 | -1.96455108920222 | 0.761172931240712 | 0.009852817141497 |
| Boiled/baked potatoes | Fracture at wrist and hand level (finn-b-ST19_FRACT_WRIST_HAND_LEVEL) | rs9962730 | 1.16091757485219 | 0.437968904207801 | 0.0080328737451792 |
| Boiled/baked potatoes | Fracture at wrist and hand level (finn-b-ST19_FRACT_WRIST_HAND_LEVEL) | All - Inverse variance weighted | 0.33830575831997 | 0.168614910591337 | 0.044815610476984 |
| Boiled/baked potatoes | Open wound of wrist and hand (finn-b-ST19_OPEN_WOUND_WRIST_HAND) | rs1614617 | -1.56262310581191 | 0.514746434855687 | 0.0023996663848087 |
| Boiled/baked potatoes | Open wound of wrist and hand (finn-b-ST19_OPEN_WOUND_WRIST_HAND) | All - Inverse variance weighted | -0.459388022015689 | 0.172179281033591 | 0.0076286188940056 |
| Boiled/baked potatoes | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | All - Inverse variance weighted | 0.788389964662204 | 0.246939387319623 | 0.0014097582008321 |
| Boiled/baked potatoes | Fractured/broken bones in last 5 years (ukb-a-308) | rs16841871 | 0.0464310260186549 | 0.0212552396057551 | 0.0289291358660349 |
| Boiled/baked potatoes | Fractured/broken bones in last 5 years (ukb-a-308) | rs9962730 | 0.0401881466415885 | 0.0192884805178832 | 0.0372028512168741 |
| Boiled/baked potatoes | Fractured/broken bones in last 5 years (ukb-a-308) | All - Inverse variance weighted | 0.0202015055272828 | 0.007271010700349 | 0.0054633582851726 |
| Boiled/baked potatoes | Heel bone mineral density (BMD) T-score automated (ukb-a-500) | rs12514848 | -0.252793067455639 | 0.0883336211881143 | 0.0042124398051812 |
| Boiled/baked potatoes | Heel bone mineral density (BMD) T-score automated (ukb-a-500) | rs9962730 | -0.49311848858731 | 0.0833982787222107 | 3.36312411189227e-09 |
| Boiled/baked potatoes | Heel bone mineral density (BMD) T-score automated (ukb-a-500) | All - Inverse variance weighted | -0.14429110488299 | 0.0521187759652157 | 0.0056314078340463 |
| Boiled/baked potatoes | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | rs9962730 | 0.0212267928977043 | 0.0080775564934889 | 0.0085920577994982 |
| Boiled/baked potatoes | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | All - Inverse variance weighted | 0.0079273246113383 | 0.0028418379799167 | 0.0052788488754594 |
| Boiled/baked potatoes | Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) | rs9962730 | 0.0262407869041298 | 0.0070800673152206 | 0.0002103169745072 |
| Boiled/baked potatoes | Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) | All - Inverse variance weighted | 0.0131683742828538 | 0.0049052743741005 | 0.0072631064275975 |
| Boiled/baked potatoes | Fractured/broken bones in last 5 years (ukb-b-13346) | rs16841871 | 0.0365089435192528 | 0.0182012008609947 | 0.0448718744059869 |
| Boiled/baked potatoes | Fractured/broken bones in last 5 years (ukb-b-13346) | rs9962730 | 0.0521022507401974 | 0.0166218198507906 | 0.0017210643719667 |
| Boiled/baked potatoes | Fractured/broken bones in last 5 years (ukb-b-13346) | All - Inverse variance weighted | 0.0164363888592248 | 0.0072226381724251 | 0.0228653714045949 |
| Boiled/baked potatoes | Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) | rs9962730 | -0.438477368106864 | 0.0690814952138398 | 2.19200914463285e-10 |
| Boiled/baked potatoes | Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) | All - Inverse variance weighted | -0.110925825353512 | 0.0447387540384813 | 0.0131599019687485 |
| Boiled/baked potatoes | Diagnoses - main ICD10: S52.50 Fracture of lower end of radius (closed) (ukb-b-2804) | rs16841871 | 0.009650969877774 | 0.0046727339098473 | 0.0388870854241452 |
| Boiled/baked potatoes | Diagnoses - main ICD10: S52.50 Fracture of lower end of radius (closed) (ukb-b-2804) | All - Inverse variance weighted | 0.0082333895569614 | 0.0033154037960532 | 0.0130144149693821 |
| Boiled/baked potatoes | Non-cancer illness code, self-reported: sciatica (ukb-b-8194) | All - Inverse variance weighted | 0.0058792442810621 | 0.0029179667570283 | 0.0439211239877152 |
| Boiled/baked potatoes | Heel bone mineral density (BMD) (ukb-b-8875) | rs9962730 | -0.438669354475832 | 0.069066646268115 | 2.1337499766115e-10 |
| Boiled/baked potatoes | Heel bone mineral density (BMD) (ukb-b-8875) | All - Inverse variance weighted | -0.107962618312513 | 0.0455004645282826 | 0.0176547486779691 |