ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Cheesecake (ukb-b-1814)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Cheesecake (👉 📊) Osteoarthritis (hip) (ebi-a-GCST007091) Inverse variance weighted 26 -0.719223771 0.308223313 0.019624526
Cheesecake (👉 📊) Frozen shoulder (ebi-a-GCST90000512) MR Egger 19 1.915708922 0.871009505 0.041973162
Cheesecake (👉 📊) Frozen shoulder (ebi-a-GCST90000513) MR Egger 18 -2.663086873 0.824357322 0.005231267
Cheesecake (👉 📊) Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) MR Egger 20 -1.83059399 0.708173734 0.018680704
Cheesecake (👉 📊) Osteoporosis (ebi-a-GCST90038656) MR Egger 21 -0.035240047 0.015196281 0.031692926
Cheesecake (👉 📊) Fractures (ebi-a-GCST90038703) MR Egger 21 -0.037672453 0.01607344 0.030116411
Cheesecake (👉 📊) Fractures (ebi-a-GCST90038703) Weighted median 21 -0.021708773 0.010885608 0.046123238
Cheesecake (👉 📊) Fractures (ebi-a-GCST90038703) Inverse variance weighted 21 -0.020126103 0.007944808 0.011301363
Cheesecake (👉 📊) Fracture of upper limb or shoulder (ebi-a-GCST90038704) Weighted median 21 -0.015733037 0.007352086 0.03235947
Cheesecake (👉 📊) Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) Weighted mode 26 16.75720093 7.863926883 0.043114619
Cheesecake (👉 📊) Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) Weighted mode 26 16.32329169 7.747511997 0.045328253
Cheesecake (👉 📊) Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) Inverse variance weighted 26 0.719120917 0.33970937 0.034270797
Cheesecake (👉 📊) Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) Simple mode 26 -20.34118287 9.48792003 0.0419551
Cheesecake (👉 📊) Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) Weighted median 26 2.737513018 1.383289286 0.047817348
Cheesecake (👉 📊) Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) Inverse variance weighted 26 1.189248068 0.579674673 0.040210648
Cheesecake (👉 📊) Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) Simple mode 26 -21.09270176 10.02179583 0.045538622
Cheesecake (👉 📊) Cervical disc disorders (finn-b-M13_CERVICDISC) MR Egger 26 2.428726162 1.176532783 0.049958062
Cheesecake (👉 📊) Lower back pain or/and sciatica (finn-b-M13_LOWBACKPAINORANDSCIATICA) Inverse variance weighted 26 -0.661367946 0.336142906 0.049123273
Cheesecake (👉 📊) Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) Inverse variance weighted 26 1.310012598 0.607937364 0.031173733
Cheesecake (👉 📊) Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) Inverse variance weighted 26 1.200218834 0.599334591 0.045221784
Cheesecake (👉 📊) Other/unspecified rheumatoid arthritis (finn-b-RHEUMA_NOS) Inverse variance weighted 26 2.366448806 1.066822867 0.026539773
Cheesecake (👉 📊) Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS) MR Egger 26 3.040962185 1.307027742 0.028751293
Cheesecake (👉 📊) Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS) Inverse variance weighted 26 1.899166091 0.711049585 0.007564065
Cheesecake (👉 📊) Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) MR Egger 26 2.914084501 1.304785669 0.035107425
Cheesecake (👉 📊) Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) Inverse variance weighted 26 1.820645368 0.709082908 0.010240354
Cheesecake (👉 📊) Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) MR Egger 26 2.891631109 1.286447598 0.034050218
Cheesecake (👉 📊) Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) Inverse variance weighted 26 1.780014949 0.7000533 0.011000438
Cheesecake (👉 📊) Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) Simple mode 26 3.803978234 1.83838262 0.049013921
Cheesecake (👉 📊) Burn and corrosion of wrist and hand (finn-b-ST19_BURN_CORROSION_WRIST_HAND) MR Egger 26 8.423715486 3.379891753 0.019993604
Cheesecake (👉 📊) Contusion of ankle (finn-b-ST19_CONTU_ANKLE) MR Egger 26 -6.977923759 3.293433041 0.044655903
Cheesecake (👉 📊) Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) Inverse variance weighted 26 -1.917722053 0.840757411 0.022551657
Cheesecake (👉 📊) Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) MR Egger 26 -9.739799537 4.065860824 0.024752058
Cheesecake (👉 📊) Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) Inverse variance weighted 26 -3.151576026 1.131613828 0.005352313
Cheesecake (👉 📊) Superficial injury of ankle and foot (finn-b-ST19_SUPERF_INJURY_ANKLE_FOOT) MR Egger 26 -4.530822773 1.9113855 0.026144214
Cheesecake (👉 📊) Osteocrin (prot-a-2157) Inverse variance weighted 26 1.773858727 0.735724009 0.01590718
Cheesecake (👉 📊) Osteocalcin (prot-a-246) MR Egger 26 -2.547646034 1.141240685 0.035184568
Cheesecake (👉 📊) Bone morphogenetic protein 6 (prot-a-255) MR Egger 26 2.388136236 1.141125204 0.047117252
Cheesecake (👉 📊) Bone morphogenetic protein 6 (prot-a-256) MR Egger 26 4.015960166 1.260928025 0.003983356
Cheesecake (👉 📊) Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) MR Egger 26 -0.031370881 0.013751176 0.031695054
Cheesecake (👉 📊) Operative procedures - secondary OPCS: S06.5 Excision of lesion of skin of head or neck NEC (ukb-b-12747) Inverse variance weighted 5 0.014599316 0.006413881 0.02283366
Cheesecake (👉 📊) Operation code: knee surgery (not replacement) (ukb-b-1508) Inverse variance weighted 13 -0.031861346 0.013740086 0.020402588
Cheesecake (👉 📊) Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) Weighted median 7 0.029392815 0.013927747 0.034825788
Cheesecake (👉 📊) Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) Inverse variance weighted 7 0.029405575 0.010956239 0.00727664
Cheesecake (👉 📊) Diagnoses - secondary ICD10: M81.99 Osteoporosis, unspecified (Site unspecified) (ukb-b-17796) Inverse variance weighted 6 -0.01509907 0.007377899 0.040704558
Cheesecake (👉 📊) Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) Inverse variance weighted 26 0.049487696 0.024586192 0.044133068
Cheesecake (👉 📊) Operative procedures - secondary OPCS: Z67.5 Lumbar intervertebral joint (ukb-b-19054) Weighted median 6 -0.018380749 0.00898743 0.0408389
Cheesecake (👉 📊) Operative procedures - main OPCS: W26.2 Manipulation of fracture of bone NEC (ukb-b-1935) Weighted median 4 0.01741943 0.008569051 0.042069642
Cheesecake (👉 📊) Diagnoses - main ICD10: M51.3 Other specified intervertebral disk degeneration (ukb-b-19807) Inverse variance weighted 2 -0.023471358 0.009358876 0.012144248
Cheesecake (👉 📊) Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) Inverse variance weighted 26 0.195502619 0.077662326 0.011824406
Cheesecake (👉 📊) Fractured heel (right) (ukb-b-3499) Inverse variance weighted 26 0.0216458 0.010964511 0.048362512
Cheesecake (👉 📊) Operation code: reduction or fixation of bone fracture (ukb-b-847) MR Egger 18 -0.069520696 0.030089903 0.034529483
Cheesecake (👉 📊) Heel bone mineral density (BMD) (ukb-b-8875) Inverse variance weighted 26 0.189987778 0.078557531 0.015586615
Cheesecake (👉 📊) Diagnoses - main ICD10: M13 Other arthritis (ukb-d-M13) MR Egger 21 0.019887827 0.008194645 0.025342281
Cheesecake (👉 📊) Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) MR Egger 20 0.02158801 0.008107189 0.01585311
Cheesecake (👉 📊) Other arthritis (FG) (ukb-d-RHEU_ARTHRITIS_OTH) MR Egger 21 0.019887827 0.008194645 0.025342281
Cheesecake (👉 📊) Heel bone mineral density (BMD) (right) (ukb-e-4124_AFR) MR Egger 13 4.306448388 1.711613386 0.028677959
Cheesecake (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) MR Egger 13 4.171903595 1.681427277 0.030510358
Cheesecake (👉 📊) Open wounds of head; neck; and trunk (ukb-e-870_CSA) Weighted median 16 7.404996893 3.73183042 0.047224622
Cheesecake (👉 📊) Open wounds of head; neck; and trunk (ukb-e-870_CSA) Inverse variance weighted 16 5.540042954 2.654348981 0.036873948

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Cheesecake Osteoarthritis (hip) (ebi-a-GCST007091) All - Inverse variance weighted -0.719223771153825 0.308223312786718 0.0196245257124668
Cheesecake Frozen shoulder (ebi-a-GCST90000512) rs117977709 3.86625580713259 1.96090437377113 0.0486473207469906
Cheesecake Frozen shoulder (ebi-a-GCST90000512) rs146462193 4.14370562956736 1.93328185630089 0.032084757278625
Cheesecake Frozen shoulder (ebi-a-GCST90000512) All - MR Egger 1.91570892219723 0.871009505034633 0.0419731621089164
Cheesecake Frozen shoulder (ebi-a-GCST90000513) rs146462193 -5.26825072572842 1.82450241583668 0.0038831660595394
Cheesecake Frozen shoulder (ebi-a-GCST90000513) All - MR Egger -2.66308687263891 0.824357322104152 0.0052312669025279
Cheesecake Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) rs145639946 -4.23660319906772 1.9284626806759 0.0280289395967334
Cheesecake Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) All - MR Egger -1.83059398979538 0.708173734483658 0.0186807040324719
Cheesecake Osteoporosis (ebi-a-GCST90038656) rs28381866 -0.071366496021711 0.0319987047431074 0.0257279792979442
Cheesecake Osteoporosis (ebi-a-GCST90038656) rs73084384 -0.0827421907008943 0.0332543337901414 0.0128404999453426
Cheesecake Osteoporosis (ebi-a-GCST90038656) All - MR Egger -0.0352400474367274 0.0151962808383858 0.031692926482204
Cheesecake Fractures (ebi-a-GCST90038703) rs1394426 0.088111386350047 0.035751654171403 0.0137189200881901
Cheesecake Fractures (ebi-a-GCST90038703) rs28381866 -0.0719795842842164 0.0338459877875779 0.0334466828956713
Cheesecake Fractures (ebi-a-GCST90038703) rs28694319 -0.0843567951983457 0.0376802932102657 0.0251721202400035
Cheesecake Fractures (ebi-a-GCST90038703) All - Inverse variance weighted -0.0201261029950119 0.0079448078397455 0.0113013627192904
Cheesecake Fractures (ebi-a-GCST90038703) All - MR Egger -0.0376724532131954 0.0160734395587156 0.0301164110400621
Cheesecake Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) rs10179681 20.1666334518578 9.33161315586137 0.0306869182369602
Cheesecake Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) rs145774296 26.8865100933313 12.3626798265459 0.0296441731849462
Cheesecake Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) rs28381866 23.9530006784679 11.4291001048541 0.0361007697138138
Cheesecake Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) rs10179681 20.0058038508201 9.31762797316243 0.0317859634504011
Cheesecake Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) rs145774296 27.1731646380705 12.4076452453285 0.0285217729128514
Cheesecake Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) rs28381866 23.7062850798742 11.4044285449948 0.0376457437705026
Cheesecake Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs2392968 4.03110237762872 1.43305174038464 0.0049089338475809
Cheesecake Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs3931851 3.08880892054058 1.30651330868831 0.0180709159439756
Cheesecake Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs79910083 3.10446274433662 1.35068399481675 0.0215369012538487
Cheesecake Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) All - Inverse variance weighted 0.719120916964194 0.339709370183413 0.0342707968063688
Cheesecake Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) rs650058 47.8005487554967 18.1304280552724 0.0083770623584511
Cheesecake Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) rs1394426 -10.5525293874145 4.91487670098758 0.0317885988775997
Cheesecake Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs12724320 -5.87446569614841 2.13176487117963 0.0058569942057487
Cheesecake Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs145774296 4.36445596058781 1.6946342203699 0.0100107994024268
Cheesecake Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs3931851 3.86667522571339 1.95599391300736 0.0480603997401257
Cheesecake Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs650058 5.69307252289336 2.19691180344017 0.0095586914577666
Cheesecake Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) All - Inverse variance weighted 1.18924806814034 0.579674672732931 0.0402106480323177
Cheesecake Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) rs1394426 -50.1080878632771 20.7108173282257 0.0155454402624303
Cheesecake Cervical disc disorders (finn-b-M13_CERVICDISC) rs12724320 -5.85024109533955 2.22866327441507 0.0086648967260251
Cheesecake Cervical disc disorders (finn-b-M13_CERVICDISC) rs1509520 8.6491377474984 3.26005961251863 0.0079765401182518
Cheesecake Cervical disc disorders (finn-b-M13_CERVICDISC) rs28381866 3.870350952939 1.59748350089434 0.0154022543881094
Cheesecake Cervical disc disorders (finn-b-M13_CERVICDISC) rs28694319 7.79260081204449 2.69840869543288 0.0038788422280202
Cheesecake Cervical disc disorders (finn-b-M13_CERVICDISC) rs73084384 6.2552097314251 3.18941523855272 0.0498509966177808
Cheesecake Cervical disc disorders (finn-b-M13_CERVICDISC) rs79851982 10.0694538393175 4.60597382108508 0.028802978881827
Cheesecake Cervical disc disorders (finn-b-M13_CERVICDISC) All - MR Egger 2.42872616193299 1.17653278301209 0.0499580620213312
Cheesecake Lower back pain or/and sciatica (finn-b-M13_LOWBACKPAINORANDSCIATICA) rs28381866 -2.57201011533954 1.00536606426941 0.0105190687890317
Cheesecake Lower back pain or/and sciatica (finn-b-M13_LOWBACKPAINORANDSCIATICA) All - Inverse variance weighted -0.661367945870654 0.336142905797292 0.049123273364983
Cheesecake Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) rs145774296 4.1564908987182 1.9222716529569 0.0305965463068706
Cheesecake Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) rs28694319 6.06091174270127 2.90856513588715 0.0371769957493888
Cheesecake Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) rs79910083 8.80266084746979 2.31093589738178 0.0001394552600793
Cheesecake Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) All - Inverse variance weighted 1.31001259754104 0.60793736381666 0.0311737326055491
Cheesecake Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) rs28694319 7.16213149068166 2.84972133255996 0.0119616277270683
Cheesecake Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) rs79910083 8.60850002321488 2.25817480383425 0.0001377634872056
Cheesecake Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) All - Inverse variance weighted 1.20021883424883 0.59933459067818 0.0452217843747355
Cheesecake Other/unspecified rheumatoid arthritis (finn-b-RHEUMA_NOS) rs12724320 9.79885102718363 4.1181821375061 0.0173402938573487
Cheesecake Other/unspecified rheumatoid arthritis (finn-b-RHEUMA_NOS) rs149946736 24.4798041615667 8.63654077314467 0.0045905286742092
Cheesecake Other/unspecified rheumatoid arthritis (finn-b-RHEUMA_NOS) rs79910083 11.7256254300029 3.97607600974181 0.0031875798567912
Cheesecake Other/unspecified rheumatoid arthritis (finn-b-RHEUMA_NOS) All - Inverse variance weighted 2.36644880582287 1.06682286689054 0.0265397727274959
Cheesecake Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS) rs28694319 8.0195697677351 3.36250304726839 0.017079121353364
Cheesecake Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS) rs73084384 8.82652124157613 3.94526779785536 0.0252704875731762
Cheesecake Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS) rs79910083 10.3643892164767 2.7034784333754 0.0001262179343639
Cheesecake Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS) All - Inverse variance weighted 1.89916609080286 0.711049584934406 0.0075640651367247
Cheesecake Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS) All - MR Egger 3.04096218468789 1.3070277421112 0.028751293031908
Cheesecake Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) rs28694319 7.817819584899 3.36250304726839 0.0200719602005481
Cheesecake Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) rs73084384 8.93954592334101 3.95233184046566 0.0237072330587552
Cheesecake Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) rs79910083 10.1048046362228 2.68026355221449 0.0001631960506507
Cheesecake Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) All - Inverse variance weighted 1.82064536817679 0.709082907681208 0.0102403541997808
Cheesecake Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) All - MR Egger 2.91408450132676 1.30478566934182 0.0351074245943999
Cheesecake Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) rs28694319 8.32219504198926 3.34569053203204 0.0128667173059092
Cheesecake Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) rs73084384 8.86890549723796 3.92760769132959 0.023939829232071
Cheesecake Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) rs79910083 9.69537855029398 2.65704867105358 0.0002633371760452
Cheesecake Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) All - Inverse variance weighted 1.78001494927985 0.700053299639779 0.0110004383905435
Cheesecake Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) All - MR Egger 2.89163110891666 1.28644759817787 0.0340502184946781
Cheesecake Burn and corrosion of wrist and hand (finn-b-ST19_BURN_CORROSION_WRIST_HAND) rs149946736 36.1351548649494 16.6995076595441 0.0304762071452001
Cheesecake Burn and corrosion of wrist and hand (finn-b-ST19_BURN_CORROSION_WRIST_HAND) rs79851982 48.355440481369 18.7277688396401 0.0098224397321008
Cheesecake Burn and corrosion of wrist and hand (finn-b-ST19_BURN_CORROSION_WRIST_HAND) All - MR Egger 8.42371548609066 3.37989175261365 0.0199936041246105
Cheesecake Contusion of ankle (finn-b-ST19_CONTU_ANKLE) rs73084384 -24.7983215834758 11.7227787118012 0.0343961930904851
Cheesecake Contusion of ankle (finn-b-ST19_CONTU_ANKLE) All - MR Egger -6.97792375880132 3.29343304108375 0.0446559028754948
Cheesecake Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) rs1509520 -12.9537470725995 5.68847136470087 0.0227747040176229
Cheesecake Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) rs79851982 17.4123709838219 7.66552263129523 0.0231156516111728
Cheesecake Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) All - Inverse variance weighted -1.91772205281603 0.840757411463927 0.0225516566820499
Cheesecake Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) rs142750856 41.3511151081612 19.574329455328 0.0346420796377242
Cheesecake Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) rs650058 24.0124822386767 10.405802681886 0.0210211164833419
Cheesecake Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) All - MR Egger -9.73979953733935 4.06586082371521 0.0247520576930527
Cheesecake Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) rs145774296 -9.19823847971919 4.03002565839209 0.022464155868626
Cheesecake Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) rs28381866 -7.1825078640597 3.64213902423981 0.0486030339411985
Cheesecake Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) rs28694319 -15.5599828512345 5.92641162081053 0.0086513698091187
Cheesecake Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) All - Inverse variance weighted -3.15157602555509 1.13161382780523 0.0053523125784375
Cheesecake Superficial injury of ankle and foot (finn-b-ST19_SUPERF_INJURY_ANKLE_FOOT) rs146462193 -14.986984130087 6.87446445967035 0.0292504361337401
Cheesecake Superficial injury of ankle and foot (finn-b-ST19_SUPERF_INJURY_ANKLE_FOOT) All - MR Egger -4.53082277313828 1.91138549984539 0.0261442138449235
Cheesecake Osteocrin (prot-a-2157) rs10179681 8.34565777558677 3.34595496071912 0.0126222585814513
Cheesecake Osteocrin (prot-a-2157) rs142750856 10.2505982192224 3.07655600089016 0.000862732503641
Cheesecake Osteocrin (prot-a-2157) rs3931851 7.26512024831305 3.25117907162034 0.0254429034704229
Cheesecake Osteocrin (prot-a-2157) All - Inverse variance weighted 1.77385872721259 0.735724009274336 0.015907180108786
Cheesecake Osteocalcin (prot-a-246) rs145774296 -7.05395007152312 3.15882066947888 0.0255426087072432
Cheesecake Osteocalcin (prot-a-246) All - MR Egger -2.54764603427477 1.14124068543285 0.0351845681057768
Cheesecake Bone morphogenetic protein 6 (prot-a-255) rs28381866 8.81083081477826 3.13020415715784 0.0048810890353692
Cheesecake Bone morphogenetic protein 6 (prot-a-255) rs73084384 7.04285048247411 3.29537587770729 0.0325823903077116
Cheesecake Bone morphogenetic protein 6 (prot-a-255) rs79910083 6.42419075034717 3.10868363182043 0.0387783788434907
Cheesecake Bone morphogenetic protein 6 (prot-a-255) All - MR Egger 2.38813623624483 1.1411252038469 0.0471172523571712
Cheesecake Bone morphogenetic protein 6 (prot-a-256) rs28381866 7.01289089002652 3.13328810214026 0.0252087342239485
Cheesecake Bone morphogenetic protein 6 (prot-a-256) rs79851982 6.66648628510416 2.58292522004816 0.0098519410780646
Cheesecake Bone morphogenetic protein 6 (prot-a-256) rs79910083 11.0924923074326 3.10446274433662 0.0003528075404281
Cheesecake Bone morphogenetic protein 6 (prot-a-256) All - MR Egger 4.0159601660078 1.26092802506296 0.0039833564569586
Cheesecake Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs13017478 0.0842631465107249 0.0337260543138067 0.0124734752276976
Cheesecake Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs149946736 -0.0906677607565687 0.0340411985224298 0.0077338971905619
Cheesecake Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs73084384 -0.0715103629505093 0.0306567440414801 0.019668391889639
Cheesecake Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) All - MR Egger -0.0313708814533309 0.0137511760969858 0.031695054117094
Cheesecake Operative procedures - secondary OPCS: S06.5 Excision of lesion of skin of head or neck NEC (ukb-b-12747) rs650058 0.0303759672022328 0.0137095564482314 0.0267135397034304
Cheesecake Operative procedures - secondary OPCS: S06.5 Excision of lesion of skin of head or neck NEC (ukb-b-12747) All - Inverse variance weighted 0.0145993164251746 0.0064138808097458 0.0228336601949306
Cheesecake Operation code: knee surgery (not replacement) (ukb-b-1508) All - Inverse variance weighted -0.0318613459246041 0.0137400859252447 0.0204025880501663
Cheesecake Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) rs1394426 0.0604358996261277 0.0287496632520977 0.0355407624921512
Cheesecake Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) All - Inverse variance weighted 0.0294055748728396 0.0109562393495337 0.0072766403450783
Cheesecake Diagnoses - secondary ICD10: M81.99 Osteoporosis, unspecified (Site unspecified) (ukb-b-17796) rs13017478 -0.0404089562273768 0.019102344598979 0.0343965096933474
Cheesecake Diagnoses - secondary ICD10: M81.99 Osteoporosis, unspecified (Site unspecified) (ukb-b-17796) All - Inverse variance weighted -0.0150990697864766 0.0073778994698489 0.0407045578967749
Cheesecake Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) rs2392968 0.296122100132171 0.117373123372352 0.0116387413406942
Cheesecake Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) rs882488 0.267779510489419 0.118256918144357 0.0235502800189203
Cheesecake Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) All - Inverse variance weighted 0.0494876958801327 0.0245861918720363 0.0441330676121526
Cheesecake Diagnoses - main ICD10: M51.3 Other specified intervertebral disk degeneration (ukb-b-19807) rs882488 -0.0285657707374968 0.0133293728495811 0.0321075281656893
Cheesecake Diagnoses - main ICD10: M51.3 Other specified intervertebral disk degeneration (ukb-b-19807) All - Inverse variance weighted -0.0234713583427111 0.0093588761480287 0.0121442481733411
Cheesecake Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) rs2392968 1.69055773548958 0.343028254831653 8.29338482226435e-07
Cheesecake Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) rs28381866 0.729451674582125 0.354527231234195 0.0396349306071547
Cheesecake Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) All - Inverse variance weighted 0.195502619385254 0.0776623258811508 0.0118244056791691
Cheesecake Fractured heel (right) (ukb-b-3499) rs12724320 0.137216617591663 0.0543200336237459 0.0115344016030651
Cheesecake Fractured heel (right) (ukb-b-3499) rs145774296 0.114562893974353 0.0569914200360285 0.0444123618403604
Cheesecake Fractured heel (right) (ukb-b-3499) All - Inverse variance weighted 0.021645799647505 0.0109645111276488 0.0483625122407049
Cheesecake Operation code: reduction or fixation of bone fracture (ukb-b-847) rs12724320 0.127569170319535 0.056726384345094 0.0245219951493528
Cheesecake Operation code: reduction or fixation of bone fracture (ukb-b-847) All - MR Egger -0.0695206956835047 0.0300899026684727 0.0345294832296771
Cheesecake Heel bone mineral density (BMD) (ukb-b-8875) rs2392968 1.71042457508469 0.342974644262947 6.13147926608451e-07
Cheesecake Heel bone mineral density (BMD) (ukb-b-8875) All - Inverse variance weighted 0.189987777691351 0.0785575310821397 0.0155866148383564
Cheesecake Diagnoses - main ICD10: M13 Other arthritis (ukb-d-M13) rs73084384 0.0359980079399839 0.0173693505319224 0.0382186809034701
Cheesecake Diagnoses - main ICD10: M13 Other arthritis (ukb-d-M13) All - MR Egger 0.0198878266318293 0.0081946449888083 0.0253422809536351
Cheesecake Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) All - MR Egger 0.0215880097809528 0.0081071886381653 0.0158531101692859
Cheesecake Other arthritis (FG) (ukb-d-RHEU_ARTHRITIS_OTH) rs73084384 0.0359980079399839 0.0173693505319224 0.0382186809034701
Cheesecake Other arthritis (FG) (ukb-d-RHEU_ARTHRITIS_OTH) All - MR Egger 0.0198878266318293 0.0081946449888083 0.0253422809536351
Cheesecake Heel bone mineral density (BMD) (right) (ukb-e-4124_AFR) rs10179681 6.78980620033075 2.71417433229493 0.0123629959223929
Cheesecake Heel bone mineral density (BMD) (right) (ukb-e-4124_AFR) All - MR Egger 4.30644838780332 1.71161338571879 0.0286779593315691
Cheesecake Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) rs10179681 6.34927294531444 2.66697434068604 0.0172796526171852
Cheesecake Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) rs2392968 -14.4645438256089 6.73946706970817 0.0318534805741338
Cheesecake Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) All - MR Egger 4.17190359487337 1.6814272767647 0.0305103582178823
Cheesecake Open wounds of head; neck; and trunk (ukb-e-870_CSA) rs882488 23.3850932081612 11.4762833465567 0.0415810722366369
Cheesecake Open wounds of head; neck; and trunk (ukb-e-870_CSA) All - Inverse variance weighted 5.54004295396783 2.65434898079529 0.0368739484553298