ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Other savoury snack | Frozen shoulder (ebi-a-GCST90000513) | rs117606244 | -2.5836259361556 | 1.27843400753384 | 0.0432869877732832 |
| Other savoury snack | Frozen shoulder (ebi-a-GCST90000513) | All - Inverse variance weighted | -1.05116144242233 | 0.405160651590281 | 0.0094747569636482 |
| Other savoury snack | Osteoprotegerin levels (ebi-a-GCST90010243) | rs12061341 | 11.8107940727762 | 5.42408954276997 | 0.0294454928476899 |
| Other savoury snack | Osteoprotegerin levels (ebi-a-GCST90010243) | All - Inverse variance weighted | 2.47204963997699 | 1.17032960113992 | 0.0346634781472673 |
| Other savoury snack | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs11061369 | 2.06550543784393 | 0.973398616346751 | 0.0338417434272262 |
| Other savoury snack | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | rs113470581 | 1.76634521206868 | 0.864349559035679 | 0.0409976031549236 |
| Other savoury snack | Fractured bones in last 5 years (UKB data field 2463) (Firth correction) (ebi-a-GCST90013913) | All - Inverse variance weighted | 0.513845044302778 | 0.254782765844919 | 0.0437167322780069 |
| Other savoury snack | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs11061369 | 2.09463148316651 | 0.999803573233965 | 0.0361671696789379 |
| Other savoury snack | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | rs113470581 | 1.79482995625413 | 0.891791116125208 | 0.0441554099044852 |
| Other savoury snack | Fractured bones in last 5 years (UKB data field 2463) (SPA correction) (ebi-a-GCST90013963) | All - Inverse variance weighted | 0.508266864335059 | 0.25522373999791 | 0.0464307710543351 |
| Other savoury snack | Neck circumference (ebi-a-GCST90017134) | rs17151237 | 18.6266985689134 | 6.30671301521376 | 0.0031422139235193 |
| Other savoury snack | Neck circumference (ebi-a-GCST90017134) | rs17810066 | 19.2339874220627 | 9.71686145375044 | 0.0477659887397646 |
| Other savoury snack | Neck circumference (ebi-a-GCST90017134) | All - Inverse variance weighted | 6.69907736962123 | 2.50889081054995 | 0.0075820737279222 |
| Other savoury snack | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | rs17151237 | 18.6266985689134 | 6.30671301521376 | 0.0031422139235193 |
| Other savoury snack | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | rs17810066 | 19.2339874220627 | 9.71686145375044 | 0.0477659887397646 |
| Other savoury snack | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | All - Inverse variance weighted | 6.69907736962123 | 2.50889081054995 | 0.0075820737279222 |
| Other savoury snack | Other joint disorder (ebi-a-GCST90038688) | rs77508220 | -0.0562930650527915 | 0.0274402001624355 | 0.0402200721119602 |
| Other savoury snack | Other joint disorder (ebi-a-GCST90038688) | All - MR Egger | -0.0297154918040124 | 0.0127571789613169 | 0.0332680052009862 |
| Other savoury snack | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | rs441414 | -0.0608570411900505 | 0.0255924215861554 | 0.0174100307605047 |
| Other savoury snack | Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) | rs113182762 | -47.292146705705 | 22.6910483186362 | 0.0371441273816785 |
| Other savoury snack | Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) | rs441414 | 27.581538247904 | 12.3847876273628 | 0.0259439487090477 |
| Other savoury snack | Benign neoplasm: Connective and other soft tissue of head, face and neck (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK) | All - MR Egger | -9.01094840721332 | 4.11089665876963 | 0.0392553619068366 |
| Other savoury snack | Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) | rs113182762 | -47.3917638294555 | 22.7170353943972 | 0.0369625646141042 |
| Other savoury snack | Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) | rs441414 | 26.9566575827533 | 12.3413931367274 | 0.0289440634222233 |
| Other savoury snack | Benign neoplasm: Connective and other soft tissue of head, face and neck (all cancers excluded) (finn-b-CD2_BENIGN_CONNSOFT_HEADFACETRUNK_EXALLC) | All - MR Egger | -8.9719985896237 | 4.10803066658776 | 0.039907248136192 |
| Other savoury snack | Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) | rs113470581 | 15.8092773539166 | 7.76335162628831 | 0.0417103592170865 |
| Other savoury snack | Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) | All - Inverse variance weighted | 4.55640599866587 | 2.29882782838744 | 0.0474729486144127 |
| Other savoury snack | Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) | All - MR Egger | 10.0723306449832 | 4.07412984080059 | 0.0216361584879954 |
| Other savoury snack | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | rs113470581 | 25.7864802102521 | 10.6655788626074 | 0.0156176997961263 |
| Other savoury snack | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | rs113602890 | 67.1234186481496 | 28.1730119934744 | 0.0171935136837566 |
| Other savoury snack | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | All - Inverse variance weighted | 7.17212781398948 | 3.06630635216243 | 0.0193348046766094 |
| Other savoury snack | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | rs113182762 | 6.22823582405017 | 2.99284489180714 | 0.0374300648154822 |
| Other savoury snack | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | rs116035674 | -7.18070897039012 | 3.49449240388868 | 0.0398920780185267 |
| Other savoury snack | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | rs12061341 | -3.67052852589762 | 1.83526426294881 | 0.0455002638963584 |
| Other savoury snack | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | rs13387924 | -3.99914856836931 | 1.64481110473254 | 0.0150417392795186 |
| Other savoury snack | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | rs148536152 | 3.25814966874524 | 1.46588104604355 | 0.0262389881114143 |
| Other savoury snack | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | All - MR Egger | 1.6147448743954 | 0.618523274955001 | 0.0159643390683836 |
| Other savoury snack | Achilles tendinitis (finn-b-M13_ACHILLESTEND) | rs10493299 | -11.3767797355338 | 4.92407589029051 | 0.0208638310317753 |
| Other savoury snack | Achilles tendinitis (finn-b-M13_ACHILLESTEND) | rs113602890 | 22.9083129657406 | 8.35121100029282 | 0.0060859793717608 |
| Other savoury snack | Achilles tendinitis (finn-b-M13_ACHILLESTEND) | rs117606244 | 7.17112285156192 | 2.03360200268174 | 0.0004213841928203 |
| Other savoury snack | Achilles tendinitis (finn-b-M13_ACHILLESTEND) | rs117673370 | 14.8403222601012 | 5.50349318942718 | 0.0070066553482186 |
| Other savoury snack | Achilles tendinitis (finn-b-M13_ACHILLESTEND) | rs148536152 | 9.42802008715121 | 4.57801521996805 | 0.0394547744835731 |
| Other savoury snack | Achilles tendinitis (finn-b-M13_ACHILLESTEND) | All - MR Egger | 5.96014604592472 | 2.32551803369007 | 0.0177405810278695 |
| Other savoury snack | Ankylosing spondylitis, strict definition (finn-b-M13_ANKYLOSPON_STRICT) | All - Inverse variance weighted | -3.0011111986374 | 1.51371430740009 | 0.047410560826045 |
| Other savoury snack | Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) | rs113470581 | 4.52755947334986 | 1.56371833523487 | 0.003786992662236 |
| Other savoury snack | Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) | rs113602890 | 7.90302436342558 | 4.01874017724288 | 0.0492359490849507 |
| Other savoury snack | Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) | rs17810066 | 3.94072714513212 | 1.98655834165565 | 0.0472897785574767 |
| Other savoury snack | Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) | All - MR Egger | 2.36915351675613 | 0.858568924935158 | 0.0114403848664689 |
| Other savoury snack | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs113470581 | 23.8275830566019 | 9.86459813926017 | 0.0157151698750556 |
| Other savoury snack | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs116988849 | 22.9883815477043 | 10.2029514812784 | 0.0242521551954159 |
| Other savoury snack | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | All - Inverse variance weighted | 7.33585355407769 | 2.82484688080417 | 0.0094068463799299 |
| Other savoury snack | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | All - MR Egger | 10.7631576890006 | 5.00941780171374 | 0.0429325032120857 |
| Other savoury snack | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | rs116988849 | 24.5011305097154 | 11.7994419036865 | 0.0378509463398543 |
| Other savoury snack | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | rs6742151 | -35.8000496839548 | 15.7994976400121 | 0.0234576307342702 |
| Other savoury snack | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | All - Inverse variance weighted | 8.81789678184622 | 3.43811254193752 | 0.0103250372586796 |
| Other savoury snack | Cervical disc disorders (finn-b-M13_CERVICDISC) | rs117606244 | -2.1346874823472 | 1.00193548962536 | 0.033125094655679 |
| Other savoury snack | Cervical disc disorders (finn-b-M13_CERVICDISC) | rs13387924 | -8.26705712117205 | 2.55859505180617 | 0.001233180518482 |
| Other savoury snack | Cervical disc disorders (finn-b-M13_CERVICDISC) | All - Inverse variance weighted | -1.13846899654026 | 0.484599312111501 | 0.018808763081176 |
| Other savoury snack | Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) | rs10493299 | -17.0313504007575 | 7.31847543034935 | 0.0199561177581014 |
| Other savoury snack | Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) | All - MR Egger | 6.03803536374997 | 2.48928335112371 | 0.0239379046602269 |
| Other savoury snack | Other joint disorders (finn-b-M13_OTHERJOINT) | rs113470581 | 2.14586347634132 | 0.781859167617433 | 0.0060591113793798 |
| Other savoury snack | Other joint disorders (finn-b-M13_OTHERJOINT) | All - MR Egger | 0.904660965615804 | 0.403191170010077 | 0.0352414985672624 |
| Other savoury snack | Patellar tendinitis (finn-b-M13_PATELLARTEND) | All - Inverse variance weighted | -5.49303035151297 | 2.56412868726701 | 0.0321725647708684 |
| Other savoury snack | Transient synovitis (finn-b-M13_TRANSSYNOVITIS) | rs116988849 | -28.7611396402359 | 13.2824761539438 | 0.0303612958718879 |
| Other savoury snack | Transient synovitis (finn-b-M13_TRANSSYNOVITIS) | rs61962672 | 59.0912785499472 | 27.4289468693273 | 0.0312135148713794 |
| Other savoury snack | Transient synovitis (finn-b-M13_TRANSSYNOVITIS) | All - MR Egger | -16.3885117953451 | 6.33988612130467 | 0.0168977487274387 |
| Other savoury snack | Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) | All - MR Egger | 4.95839010445325 | 2.37818783699534 | 0.0488906994662482 |
| Other savoury snack | Dislocation, sprain and strain of joints and ligaments of thorax (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_THORAX) | rs183277736 | 22.2082239967725 | 9.99201983186794 | 0.0262430495475875 |
| Other savoury snack | Dislocation, sprain and strain of joints and ligaments of thorax (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_THORAX) | All - Inverse variance weighted | 4.21134350382831 | 2.03935608001589 | 0.0389196042843244 |
| Other savoury snack | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | rs183277736 | -0.0307517813823208 | 0.0129320659434381 | 0.0174092770019614 |
| Other savoury snack | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | All - Inverse variance weighted | -0.009046808668396 | 0.0032903645340747 | 0.0059688953929513 |
| Other savoury snack | Non-cancer illness code self-reported: joint disorder (ukb-a-86) | rs10493299 | -0.0595535865264297 | 0.0238283337278907 | 0.0124447288340149 |
| Other savoury snack | Non-cancer illness code self-reported: joint disorder (ukb-a-86) | rs13387924 | -0.062921012515615 | 0.0234232926753229 | 0.0072257222289202 |
| Other savoury snack | Non-cancer illness code self-reported: joint disorder (ukb-a-86) | rs17151237 | -0.0573382691526342 | 0.0224834996162701 | 0.0107649484107665 |
| Other savoury snack | Non-cancer illness code self-reported: joint disorder (ukb-a-86) | All - MR Egger | 0.0200914702393652 | 0.0079479880944507 | 0.0191621455626932 |
| Other savoury snack | Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) | rs10493299 | -0.0377707734451622 | 0.0160641212080219 | 0.0187104315762253 |
| Other savoury snack | Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) | All - Inverse variance weighted | -0.0281250801752403 | 0.0110575228748849 | 0.0109740365400556 |
| Other savoury snack | Heel bone mineral density (BMD) (left) (ukb-b-1096) | rs11061369 | -1.5928997501336 | 0.436376503892427 | 0.0002619468223137 |
| Other savoury snack | Heel bone mineral density (BMD) (left) (ukb-b-1096) | rs115779342 | -1.09879812230207 | 0.458404963566116 | 0.0165297835127764 |
| Other savoury snack | Heel bone mineral density (BMD) (left) (ukb-b-1096) | rs17151237 | -1.33291950702 | 0.466502640964291 | 0.0042731515828124 |
| Other savoury snack | Heel bone mineral density (BMD) (left) (ukb-b-1096) | All - MR Egger | -0.485282801339983 | 0.215273864789593 | 0.0340083142214098 |
| Other savoury snack | Operative procedures - secondary OPCS: Z85.6 Ankle joint (ukb-b-15453) | rs13387924 | 0.0493608887570173 | 0.0198137385803883 | 0.012729609755065 |
| Other savoury snack | Operative procedures - secondary OPCS: Z85.6 Ankle joint (ukb-b-15453) | All - Inverse variance weighted | 0.0256479094229744 | 0.0122167591993929 | 0.0357813291200929 |
| Other savoury snack | Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) | rs11061369 | -1.5348296431099 | 0.436604705576498 | 0.0004391320055647 |
| Other savoury snack | Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) | rs115779342 | -1.07160422356184 | 0.458608842296027 | 0.0194578587488519 |
| Other savoury snack | Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) | rs17151237 | -1.41947993318586 | 0.466529727777527 | 0.002345161724212 |
| Other savoury snack | Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) | All - MR Egger | -0.476097777467855 | 0.213417277028767 | 0.0357318361620298 |
| Other savoury snack | Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) | rs61962672 | -0.812142702321927 | 0.33595633856241 | 0.0156315920961158 |
| Other savoury snack | Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) | rs77508220 | 0.691486110019475 | 0.345607692106159 | 0.0454157443498945 |
| Other savoury snack | Non-cancer illness code, self-reported: joint disorder (ukb-b-8201) | rs10493299 | -0.0442302411309141 | 0.0202958503838479 | 0.029311238726512 |
| Other savoury snack | Non-cancer illness code, self-reported: joint disorder (ukb-b-8201) | rs13387924 | -0.0474508652996459 | 0.0199252202219312 | 0.0172447500546478 |
| Other savoury snack | Non-cancer illness code, self-reported: joint disorder (ukb-b-8201) | All - Inverse variance weighted | -0.0366837053302473 | 0.0114389008565213 | 0.0013416163401827 |
| Other savoury snack | Shoulder lesions (ukb-d-M13_SHOULDER) | rs113182762 | -0.0909686249371979 | 0.0429464579615738 | 0.0341592416317404 |
| Other savoury snack | Shoulder lesions (ukb-d-M13_SHOULDER) | rs116988849 | -0.0989456680002269 | 0.0437314114217949 | 0.0236618021925276 |
| Other savoury snack | Shoulder lesions (ukb-d-M13_SHOULDER) | rs985420 | 0.0908839304438075 | 0.0443178438859908 | 0.0402932511512061 |
| Other savoury snack | Shoulder lesions (ukb-d-M13_SHOULDER) | All - MR Egger | -0.0377953107327847 | 0.0155606362830828 | 0.0233681961012594 |
| Other savoury snack | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | rs113182762 | -0.0910911973112039 | 0.0429493598517004 | 0.0339304146499691 |
| Other savoury snack | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | rs116988849 | -0.0990188742446385 | 0.0437341127592271 | 0.0235673048073092 |
| Other savoury snack | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | rs985420 | 0.0913259726765533 | 0.0443209243196684 | 0.0393449308960208 |
| Other savoury snack | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | All - MR Egger | -0.0378126916282972 | 0.0155616881286054 | 0.0233196886614463 |
| Other savoury snack | Fractured/broken bones in last 5 years (ukb-e-2463_AFR) | rs13387924 | 17.7166581738512 | 8.70352333589193 | 0.041793238988588 |
| Other savoury snack | Fractured/broken bones in last 5 years (ukb-e-2463_AFR) | All - MR Egger | -8.60558921237987 | 3.45397517325315 | 0.0415051597722799 |
| Other savoury snack | Ankle spacing width (left) (ukb-e-4100_AFR) | rs12061341 | -4.97258432397323 | 1.91834206909052 | 0.0095384834280038 |
| Other savoury snack | Ankle spacing width (left) (ukb-e-4100_AFR) | All - Inverse variance weighted | -1.25229674985085 | 0.529623303478605 | 0.0180542019904896 |
| Other savoury snack | Ankle spacing width (left) (ukb-e-4100_CSA) | rs985420 | -5.75330228414157 | 2.14445575253218 | 0.0072992719152619 |
| Other savoury snack | Ankle spacing width (left) (ukb-e-4100_CSA) | All - MR Egger | 2.23262051536836 | 0.968719713712611 | 0.0398560636188715 |
| Other savoury snack | Ankle spacing width (right) (ukb-e-4119_AFR) | rs12061341 | -5.29658776792592 | 1.97951754452215 | 0.0074574187518224 |
| Other savoury snack | Ankle spacing width (right) (ukb-e-4119_AFR) | All - Inverse variance weighted | -1.07922107071658 | 0.524341995038537 | 0.0395672098853032 |
| Other savoury snack | Ankle spacing width (right) (ukb-e-4119_EAS) | All - MR Egger | 5.62824605871956 | 1.9553869769881 | 0.0182275961765669 |
| Other savoury snack | Other disorders of synovium, tendon, and bursa (ukb-e-727_AFR) | All - Inverse variance weighted | 6.66052058979289 | 2.19557052054482 | 0.0024164079624378 |