ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Quorn | Knee osteoarthritis (ebi-a-GCST007090) | rs118026170 | -3.74587450841385 | 1.50649300881861 | 0.0129011469253751 |
| Quorn | Knee osteoarthritis (ebi-a-GCST007090) | rs182115400 | -3.50372100602966 | 1.46327883100657 | 0.0166461499988164 |
| Quorn | Knee osteoarthritis (ebi-a-GCST007090) | rs845079 | 4.52727563589826 | 1.50375939849624 | 0.0026069919739982 |
| Quorn | Knee osteoarthritis (ebi-a-GCST007090) | All - MR Egger | -1.70167197820523 | 0.498496743668773 | 0.0023787472245382 |
| Quorn | Osteoarthritis of the hip or knee (ebi-a-GCST007092) | rs182115400 | -2.66513661795861 | 1.18827747297518 | 0.0249060281857056 |
| Quorn | Osteoarthritis of the hip or knee (ebi-a-GCST007092) | rs845079 | 3.42345224764038 | 1.23180291153415 | 0.0054489476535178 |
| Quorn | Osteoarthritis of the hip or knee (ebi-a-GCST007092) | All - MR Egger | -0.959282040603089 | 0.398883166818034 | 0.0246205602503515 |
| Quorn | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | rs150548333 | -11.0678733747403 | 5.29049045143466 | 0.0364356861358896 |
| Quorn | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | rs74855415 | 17.2160637966062 | 7.83391639340116 | 0.0279753550837528 |
| Quorn | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | All - Inverse variance weighted | -2.96068540666155 | 1.311917520517 | 0.0240229599526902 |
| Quorn | Osteopontin levels (ebi-a-GCST90010244) | rs117401530 | -21.0388759752505 | 7.25665577046693 | 0.0037405376047641 |
| Quorn | Osteopontin levels (ebi-a-GCST90010244) | rs117995071 | -11.8928084234912 | 5.19514909621215 | 0.0220669173095782 |
| Quorn | Osteopontin levels (ebi-a-GCST90010244) | rs145731440 | -12.981813218685 | 5.45647797454533 | 0.0173523228594832 |
| Quorn | Osteopontin levels (ebi-a-GCST90010244) | rs74855415 | 18.1661004661671 | 7.55097068964064 | 0.0161372416020936 |
| Quorn | Osteopontin levels (ebi-a-GCST90010244) | All - MR Egger | -6.70986228357216 | 2.71994720912675 | 0.0238931630769996 |
| Quorn | Bone mineral density (ebi-a-GCST90014022) | rs78715603 | 0.588994168003478 | 0.276685881770888 | 0.0332752197780316 |
| Quorn | Compression fracture (ebi-a-GCST90018828) | rs117751218 | -13.0757104417751 | 5.13830758652101 | 0.0109355865354233 |
| Quorn | Compression fracture (ebi-a-GCST90018828) | rs182115400 | -11.9880221630724 | 5.19107501765441 | 0.0209240275760906 |
| Quorn | Compression fracture (ebi-a-GCST90018828) | All - Inverse variance weighted | -2.73382099143507 | 1.02662903605827 | 0.0077468071369621 |
| Quorn | Heel bone mineral density (ebi-a-GCST90029004) | All - Inverse variance weighted | 0.118724952043182 | 0.057715084727048 | 0.0396778553914855 |
| Quorn | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs117321945 | 46.9146159582401 | 18.5402684563758 | 0.011392694019056 |
| Quorn | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs12824603 | -33.3348187318658 | 15.2748482417833 | 0.0290849007680998 |
| Quorn | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs144224609 | 28.7100373877777 | 9.16657957460867 | 0.0017359986716072 |
| Quorn | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | All - MR Egger | 9.67565452749327 | 4.53145420902471 | 0.0436180353306698 |
| Quorn | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs117321945 | 46.3506711409396 | 18.465697240865 | 0.0120698374162943 |
| Quorn | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs12824603 | -33.38433201628 | 15.2624699206797 | 0.0287171341233328 |
| Quorn | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs144224609 | 28.4538181720107 | 9.14298043631435 | 0.001857650897797 |
| Quorn | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | All - MR Egger | 9.53518554758146 | 4.53316489059499 | 0.0465688820131896 |
| Quorn | Melanocytic naevi of scalp and neck (finn-b-CD2_BENIGN_MELANOCYTIC_SCALPNECK) | rs117401530 | 19.6466706676943 | 7.95432735514807 | 0.0135137645817857 |
| Quorn | Melanocytic naevi of scalp and neck (finn-b-CD2_BENIGN_MELANOCYTIC_SCALPNECK) | rs144224609 | 14.661807491715 | 6.90443360382441 | 0.0337090327371044 |
| Quorn | Melanocytic naevi of scalp and neck (finn-b-CD2_BENIGN_MELANOCYTIC_SCALPNECK) | All - Inverse variance weighted | 4.45871138877881 | 2.07640228249694 | 0.0317673840255509 |
| Quorn | Disorders of continuity of bone (finn-b-M13_BONECONTINUITY) | rs76252718 | -8.69527256564117 | 4.22262437692479 | 0.0394740752286356 |
| Quorn | Disorders of continuity of bone (finn-b-M13_BONECONTINUITY) | All - Inverse variance weighted | -2.45819150655773 | 1.11178252984706 | 0.0270333249691371 |
| Quorn | Ankylosing hyperostosis [Forestier] (finn-b-M13_FORESTIER) | rs117401530 | -24.1767682460571 | 10.68091601193 | 0.0236019166921747 |
| Quorn | Ankylosing hyperostosis [Forestier] (finn-b-M13_FORESTIER) | All - MR Egger | -11.5466033281038 | 4.75814312402423 | 0.0234806442344161 |
| Quorn | Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP) | rs150548333 | 11.0011494131666 | 4.10994295114467 | 0.0074347660177646 |
| Quorn | Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP) | All - Inverse variance weighted | 3.32603715084667 | 1.61771416994191 | 0.0397815141672975 |
| Quorn | Burn and corrosion of wrist and hand (finn-b-ST19_BURN_CORROSION_WRIST_HAND) | rs117401530 | -17.7700465195629 | 6.83018074693297 | 0.0092764334098443 |
| Quorn | Burn and corrosion of wrist and hand (finn-b-ST19_BURN_CORROSION_WRIST_HAND) | rs845079 | -21.4685650295953 | 10.926251799712 | 0.0494303383636233 |
| Quorn | Burn and corrosion of wrist and hand (finn-b-ST19_BURN_CORROSION_WRIST_HAND) | All - Inverse variance weighted | -3.87158708275162 | 1.75734264758707 | 0.0275882828018874 |
| Quorn | Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) | rs1420437 | -15.8396417352003 | 8.05433572424868 | 0.0492295569218473 |
| Quorn | Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) | All - Inverse variance weighted | -3.61346697515521 | 1.56492032587714 | 0.0209412430673297 |
| Quorn | Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) | All - Inverse variance weighted | 2.02631912415752 | 1.03053516296219 | 0.0492664501054497 |
| Quorn | Traumatic amputation of wrist and hand (finn-b-ST19_TRAUMAT_AMPUT_WRIST_HAND) | rs12783252 | -17.4892777576037 | 7.67486824155225 | 0.0226805996604447 |
| Quorn | Traumatic amputation of wrist and hand (finn-b-ST19_TRAUMAT_AMPUT_WRIST_HAND) | All - Inverse variance weighted | -3.21980590497466 | 1.61986672592362 | 0.0468450965990337 |
| Quorn | Traumatic amputation of wrist and hand (finn-b-ST19_TRAUMAT_AMPUT_WRIST_HAND) | All - MR Egger | -6.53090717771031 | 2.7175152717166 | 0.0247092536960065 |
| Quorn | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | rs117321945 | 8.57568978374347 | 3.612043251305 | 0.0175873287047349 |
| Quorn | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | rs117401530 | 7.55219360911991 | 3.81722411949465 | 0.0478777704876883 |
| Quorn | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | rs150548333 | -8.40706098216828 | 3.47196591831785 | 0.0154603310011963 |
| Quorn | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | All - MR Egger | 3.69493457667 | 1.4446842945638 | 0.0183375148904431 |
| Quorn | Neck/shoulder pain for 3+ months (ukb-a-341) | All - Inverse variance weighted | 0.18310328428847 | 0.0766043863808779 | 0.016837117176452 |
| Quorn | Heel bone mineral density (BMD) T-score automated (ukb-a-500) | All - Inverse variance weighted | 0.229413464774838 | 0.1006703991664 | 0.0226755548824652 |
| Quorn | Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) | rs117995071 | -0.0971216947461335 | 0.0476842725912074 | 0.0416735188752339 |
| Quorn | Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) | rs144224609 | -0.102081443997559 | 0.0520384598528088 | 0.0498028007474104 |
| Quorn | Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) | All - Inverse variance weighted | -0.0260403602010066 | 0.0108893124325407 | 0.0167856896924847 |
| Quorn | Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) | All - MR Egger | -0.0519986746648552 | 0.0185789244383133 | 0.0107585860618423 |
| Quorn | Diagnoses - main ICD10: M25.5 Pain in joint (ukb-b-13019) | All - Inverse variance weighted | -0.0278133274956609 | 0.0133982063181191 | 0.0379032628670442 |
| Quorn | Ankle spacing width (ukb-b-4080) | rs117751218 | -0.740900176656961 | 0.35086858181384 | 0.0347192852181659 |
| Quorn | Ankle spacing width (ukb-b-4080) | rs145731440 | -1.38281297983417 | 0.367970109530146 | 0.0001713116464922 |
| Quorn | Ankle spacing width (ukb-b-4080) | All - Inverse variance weighted | -0.162303628565569 | 0.0738308881413711 | 0.0279265893324954 |
| Quorn | Ankle spacing width (ukb-b-4080) | All - MR Egger | -0.28478472145584 | 0.124184155091338 | 0.0313072485238596 |
| Quorn | Diagnoses - main ICD10: M75.0 Adhesive capsulitis of shoulder (ukb-b-4921) | rs845079 | -0.0356882098864182 | 0.016199648056311 | 0.0275930726606127 |
| Quorn | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs144224609 | -0.127521315078838 | 0.0644050825801275 | 0.0477048344688508 |
| Quorn | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs150548333 | -0.137852864569603 | 0.0623894085267476 | 0.0271360223329191 |
| Quorn | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs182115400 | -0.139943777500136 | 0.0653701993590092 | 0.0322910897859481 |
| Quorn | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs845079 | 0.164805631099024 | 0.0674370500719885 | 0.0145317079924435 |
| Quorn | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | All - MR Egger | -0.077171688911162 | 0.0240614385823117 | 0.0042314502468244 |
| Quorn | Adhesive capsulitis of shoulder (ukb-d-M13_ADHCAPSULITIS) | rs1675872 | 0.060406292253405 | 0.0216652376084161 | 0.0053007273771318 |
| Quorn | Adhesive capsulitis of shoulder (ukb-d-M13_ADHCAPSULITIS) | rs845079 | -0.0490599904015358 | 0.0218341065429531 | 0.0246436773448978 |
| Quorn | Adhesive capsulitis of shoulder (ukb-d-M13_ADHCAPSULITIS) | All - MR Egger | 0.0228125824614971 | 0.0096212103930267 | 0.031557084762478 |
| Quorn | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | rs78715603 | 0.0575980869852026 | 0.0285823675806959 | 0.0438877291083318 |
| Quorn | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | All - Inverse variance weighted | 0.0197268542237703 | 0.0067973011165755 | 0.0037059941138943 |
| Quorn | Knee pain for 3+ months (ukb-e-3773_AFR) | rs1420437 | 8.5510059641818 | 3.36494087554685 | 0.0110470995983039 |
| Quorn | Knee pain for 3+ months (ukb-e-3773_AFR) | All - Inverse variance weighted | 7.19462701271134 | 3.48969200067999 | 0.0392382444369933 |
| Quorn | Knee pain for 3+ months (ukb-e-3773_AFR) | All - MR Egger | 17.3194321049271 | 6.01919872038544 | 0.0451326129288334 |
| Quorn | Pain in joint (ukb-e-745_CSA) | All - Inverse variance weighted | -6.25979544217051 | 2.97909723429448 | 0.0356199870932294 |