ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Low calorie drink | Shoulder impingement (ebi-a-GCST90014054) | rs115443481 | -1.72128097612572 | 0.860794424297371 | 0.0455388986224133 |
| Low calorie drink | Shoulder impingement (ebi-a-GCST90014054) | rs61729097 | -1.8515575424074 | 0.818707557087789 | 0.0237245050598815 |
| Low calorie drink | Shoulder impingement (ebi-a-GCST90014054) | All - MR Egger | -1.18194270751446 | 0.442378120726859 | 0.0174155963807468 |
| Low calorie drink | Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) | rs117446805 | -15.5991966753976 | 7.53872956149849 | 0.0385266077055275 |
| Low calorie drink | Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) | rs117446805 | -15.7534495169769 | 7.55687695462547 | 0.0371010105401646 |
| Low calorie drink | Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) | rs55848565 | 10.4062717745635 | 5.30817900748257 | 0.0499464674290552 |
| Low calorie drink | Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) | rs75242511 | 10.2743381725021 | 4.37914277581229 | 0.0189660041754003 |
| Low calorie drink | Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) | All - Inverse variance weighted | 2.78927152135762 | 1.06000526811804 | 0.0085040106390761 |
| Low calorie drink | Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) | rs55848565 | 10.4587933346639 | 5.31868331950266 | 0.0492495056596099 |
| Low calorie drink | Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) | rs75242511 | 10.1802997031434 | 4.37024724492701 | 0.0198349088059467 |
| Low calorie drink | Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) | All - Inverse variance weighted | 2.77854878772671 | 1.0608419900362 | 0.008813834041028 |
| Low calorie drink | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | rs144590220 | 12.382040634319 | 5.91566567264011 | 0.0363408199074443 |
| Low calorie drink | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | rs188090736 | 1.82930250827675 | 0.88378878850794 | 0.0384672112258961 |
| Low calorie drink | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | rs890797 | 4.38370701726952 | 2.07501322140092 | 0.0346336115823225 |
| Low calorie drink | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | rs9657638 | -3.60967049272716 | 1.68712859986161 | 0.0323923738782341 |
| Low calorie drink | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | All - MR Egger | 1.6639287284063 | 0.777022358530768 | 0.0470208798112832 |
| Low calorie drink | Melanocytic naevi of upper limb, including shoulder (finn-b-CD2_BENIGN_MELANOCYTIC_UPPERLIMB) | rs188090736 | 3.67052915100163 | 1.65535042926884 | 0.0265976212810907 |
| Low calorie drink | Melanocytic naevi of upper limb, including shoulder (finn-b-CD2_BENIGN_MELANOCYTIC_UPPERLIMB) | All - Inverse variance weighted | 1.46884927043956 | 0.713683839641356 | 0.0395783081324858 |
| Low calorie drink | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | rs890797 | -13.0773271861872 | 6.18287174099056 | 0.0344223187688616 |
| Low calorie drink | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | All - Inverse variance weighted | -2.58914380212992 | 1.15048444762756 | 0.0244184055775647 |
| Low calorie drink | Chondromalacia (finn-b-M13_CHONDROMALACIA) | rs13429737 | 7.89866285659472 | 2.71871521142618 | 0.003669100644358 |
| Low calorie drink | Chondromalacia (finn-b-M13_CHONDROMALACIA) | rs73523164 | 5.42489171760197 | 2.58933939017159 | 0.036163244846807 |
| Low calorie drink | Chondromalacia (finn-b-M13_CHONDROMALACIA) | rs890797 | 6.97176330441902 | 3.03081948087772 | 0.0214318040450344 |
| Low calorie drink | Chondromalacia (finn-b-M13_CHONDROMALACIA) | All - Inverse variance weighted | 1.60515683206714 | 0.621094024774835 | 0.0097547934564203 |
| Low calorie drink | Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) | rs10888677 | 5.32358080856492 | 2.17514728327791 | 0.014386804062006 |
| Low calorie drink | Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) | rs188090736 | -2.73764098535436 | 1.10543740530834 | 0.0132669135212925 |
| Low calorie drink | Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) | All - MR Egger | -2.17108496880442 | 0.891730877721682 | 0.0262168351778326 |
| Low calorie drink | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | rs13429737 | -6.01424233168326 | 2.20753616749507 | 0.006441571358587 |
| Low calorie drink | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | All - Inverse variance weighted | -0.932885029367613 | 0.462802488029582 | 0.0438281783182588 |
| Low calorie drink | Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) | All - Inverse variance weighted | -0.342715785053784 | 0.159320130130678 | 0.0314671915311991 |
| Low calorie drink | Other/unspecified rheumatoid arthritis (finn-b-RHEUMA_NOS) | All - Inverse variance weighted | -0.546747716202866 | 0.270229174845663 | 0.0430448858512753 |
| Low calorie drink | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | rs144590220 | 5.79805468075026 | 2.53225941305984 | 0.0220400810071881 |
| Low calorie drink | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | rs75242511 | -1.98370338741816 | 0.706559310316783 | 0.0049919316375979 |
| Low calorie drink | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | All - Inverse variance weighted | -0.394113013304215 | 0.186552322049162 | 0.034633835066838 |
| Low calorie drink | Contusion of ankle (finn-b-ST19_CONTU_ANKLE) | All - Inverse variance weighted | 1.06573189603681 | 0.541461767007347 | 0.0490393280245601 |
| Low calorie drink | Fracture of forearm (finn-b-ST19_FRACT_FOREA) | rs117446805 | -1.68619527804831 | 0.781850187220606 | 0.0310311432714876 |
| Low calorie drink | Fracture of forearm (finn-b-ST19_FRACT_FOREA) | rs6441226 | 1.08621294187167 | 0.54433244491086 | 0.0459888649524741 |
| Low calorie drink | Fracture of forearm (finn-b-ST19_FRACT_FOREA) | All - MR Egger | -0.511355885220773 | 0.233467948868301 | 0.0427349597332223 |
| Low calorie drink | Fracture of skull and facial bones (finn-b-ST19_FRACT_SKULL_FACIAL_BONES) | rs75242511 | 1.82866699198894 | 0.845075434101907 | 0.0304712746324052 |
| Low calorie drink | Fracture of skull and facial bones (finn-b-ST19_FRACT_SKULL_FACIAL_BONES) | All - Inverse variance weighted | 0.444798990335248 | 0.200465244926489 | 0.0264980576443261 |
| Low calorie drink | Injury of muscle and tendon at forearm level (finn-b-ST19_INJURY_MUSCLE_TENDON_FOREA_LEVEL) | rs61729097 | 14.501387533978 | 5.04247842929259 | 0.0040294723562685 |
| Low calorie drink | Injury of muscle and tendon at forearm level (finn-b-ST19_INJURY_MUSCLE_TENDON_FOREA_LEVEL) | All - Inverse variance weighted | 1.42850509442164 | 0.717003712842334 | 0.0463353076137604 |
| Low calorie drink | Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) | rs13429737 | -6.00162062689483 | 2.36783181830804 | 0.0112560307668057 |
| Low calorie drink | Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) | rs75242511 | -5.05011996258794 | 2.10824081981213 | 0.0166013851681933 |
| Low calorie drink | Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) | All - Inverse variance weighted | -1.2857228253981 | 0.55441142321128 | 0.0203908571914273 |
| Low calorie drink | Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) | All - MR Egger | -2.28485711743327 | 1.02082639228812 | 0.0388777897726096 |
| Low calorie drink | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | rs144590220 | 61.025055043059 | 27.1898776511246 | 0.0248064551279785 |
| Low calorie drink | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | All - MR Egger | 4.82631140055631 | 2.21337481409682 | 0.0435598074643643 |
| Low calorie drink | Pain type(s) experienced in last month: Knee pain (ukb-a-476) | rs9657638 | 0.074132716027365 | 0.0361527047560619 | 0.0403113633470138 |
| Low calorie drink | Pain type(s) experienced in last month: Knee pain (ukb-a-476) | All - Inverse variance weighted | 0.0177726881120225 | 0.0089791238607494 | 0.0477783768427193 |
| Low calorie drink | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | rs144590220 | 0.0040325074551991 | 0.0018534879183969 | 0.0295827954981213 |
| Low calorie drink | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | rs6441226 | 0.0059331746105693 | 0.0021424655317416 | 0.0056173275581986 |
| Low calorie drink | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | All - MR Egger | 0.0022034582611501 | 0.0010088499701814 | 0.0432526294244435 |
| Low calorie drink | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | rs9657638 | 0.071055935625165 | 0.0309251742415055 | 0.0215804115259987 |
| Low calorie drink | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | All - Inverse variance weighted | 0.0152493946284258 | 0.0076843780865991 | 0.047203804815511 |
| Low calorie drink | Ankle spacing width (left) (ukb-b-2122) | rs10888677 | 0.296263908039197 | 0.117115091098118 | 0.0114166029456345 |
| Low calorie drink | Ankle spacing width (left) (ukb-b-2122) | All - Inverse variance weighted | 0.0670672454313796 | 0.0278343323344784 | 0.0159737328778284 |
| Low calorie drink | Operative procedures - secondary OPCS: Y76.7 Arthroscopic approach to joint (ukb-b-4455) | rs28531860 | 0.0245798245823294 | 0.007684780966467 | 0.001381412499233 |
| Low calorie drink | Operative procedures - secondary OPCS: Y76.7 Arthroscopic approach to joint (ukb-b-4455) | All - Inverse variance weighted | 0.0066929454602402 | 0.0032268756211818 | 0.0380676439774991 |
| Low calorie drink | Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC (ukb-b-5602) | rs55848565 | 0.0129590997104311 | 0.0059466661064366 | 0.0293152539785864 |
| Low calorie drink | Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC (ukb-b-5602) | rs9657638 | 0.0151747408670343 | 0.0054460011842002 | 0.0053296964015065 |
| Low calorie drink | Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC (ukb-b-5602) | All - Inverse variance weighted | 0.0059292251486304 | 0.0025542531645236 | 0.0202698711313969 |
| Low calorie drink | Ankle spacing width (right) (ukb-b-8607) | rs10888677 | 0.264231361937135 | 0.118545526938646 | 0.0258176192797798 |
| Low calorie drink | Ankle spacing width (right) (ukb-b-8607) | rs61729097 | 0.297807412178097 | 0.122773552560545 | 0.0152804012494047 |
| Low calorie drink | Ankle spacing width (right) (ukb-b-8607) | All - Inverse variance weighted | 0.0756888532573355 | 0.0281799051370784 | 0.0072331307786429 |
| Low calorie drink | Ankle spacing width (ukb-e-3143_EAS) | rs76698704 | 2.48613092407672 | 1.13488666983674 | 0.0284776761244443 |
| Low calorie drink | Ankle spacing width (ukb-e-3143_EAS) | All - MR Egger | 2.58449764767326 | 1.02901784607404 | 0.0332225497748378 |
| Low calorie drink | Ankle spacing width (right) (ukb-e-4119_AFR) | rs13429737 | -1.11840926130211 | 0.405156723708358 | 0.0057724242617457 |
| Low calorie drink | Ankle spacing width (right) (ukb-e-4119_AFR) | All - MR Egger | -1.64593703813601 | 0.597186017194038 | 0.0222516632074699 |