ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Single crust pastry | Neck circumference (ebi-a-GCST90017133) | rs728661 | 6.92088022845624 | 3.29245758441122 | 0.0355497005154957 |
| Single crust pastry | Neck circumference (ebi-a-GCST90017133) | All - MR Egger | 4.71468383481243 | 2.13862238058844 | 0.049690238259552 |
| Single crust pastry | Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) | rs113163044 | 23.2435183909242 | 11.7384689369289 | 0.0476906083006236 |
| Single crust pastry | Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) | All - Inverse variance weighted | 7.19748254271515 | 2.97163504886069 | 0.0154327428134557 |
| Single crust pastry | Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) | All - MR Egger | 13.0476332346738 | 4.91869583972381 | 0.0199106967733674 |
| Single crust pastry | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | rs144508914 | 23.3488457785451 | 11.6923349869327 | 0.0458321254392676 |
| Single crust pastry | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | rs148305053 | 13.1467925646398 | 6.18460256558732 | 0.0335257831438818 |
| Single crust pastry | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | All - Inverse variance weighted | 4.63163800821898 | 2.27255336352234 | 0.0415422651862454 |
| Single crust pastry | Monoarthritis, not elsewhere classified (finn-b-M13_MONOARTHRITIS) | All - Inverse variance weighted | -2.3176625161154 | 1.07396356588001 | 0.0309242744555352 |
| Single crust pastry | Osteoporosis (finn-b-M13_OSTEOPOROSIS) | rs113141796 | 6.09512777421804 | 2.64281821560745 | 0.021093957051121 |
| Single crust pastry | Osteoporosis (finn-b-M13_OSTEOPOROSIS) | rs144508914 | 6.64112344676525 | 2.98023186783943 | 0.0258544175313145 |
| Single crust pastry | Osteoporosis (finn-b-M13_OSTEOPOROSIS) | rs4363561 | 5.69273528334093 | 2.47549085319535 | 0.0214686812712968 |
| Single crust pastry | Osteoporosis (finn-b-M13_OSTEOPOROSIS) | All - Inverse variance weighted | 1.12543686991376 | 0.531680739164981 | 0.0342808049200641 |
| Single crust pastry | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | rs113141796 | -12.7397975587565 | 6.43032559794047 | 0.0475682132151599 |
| Single crust pastry | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | All - Inverse variance weighted | -3.01882881584224 | 1.20058860298393 | 0.0119215727181027 |
| Single crust pastry | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | rs77000583 | 4.95701515823444 | 1.68172516416523 | 0.0032027452043688 |
| Single crust pastry | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | All - MR Egger | 2.77701384870162 | 1.13910646114202 | 0.0298851818924147 |
| Single crust pastry | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | rs728661 | -32.4273475558542 | 13.5326726020494 | 0.016564854436455 |
| Single crust pastry | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | All - Inverse variance weighted | -7.00495981211598 | 2.77420881607164 | 0.0115688493034892 |
| Single crust pastry | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | rs77000583 | 9.81651964372539 | 4.91293499110382 | 0.0457061675084666 |
| Single crust pastry | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | rs9810988 | 16.8919695611192 | 8.55231395268639 | 0.0482528969671394 |
| Single crust pastry | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | All - Inverse variance weighted | 4.28400332254695 | 2.01573896981474 | 0.0335635206698265 |
| Single crust pastry | Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) | rs142897541 | 3.03301154525129 | 1.01760632252921 | 0.0028774509125813 |
| Single crust pastry | Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) | All - Inverse variance weighted | 0.994293845309214 | 0.42586911814212 | 0.0195569851560287 |
| Single crust pastry | Fracture of foot, except ankle (finn-b-ST19_FRACT_FOOT_ANKLE) | All - Inverse variance weighted | 0.983975730856407 | 0.463488512749588 | 0.033755728881152 |
| Single crust pastry | Fracture of forearm (finn-b-ST19_FRACT_FOREA) | All - Inverse variance weighted | 0.685968087061622 | 0.287054783787048 | 0.0168632164405299 |
| Single crust pastry | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | rs9810988 | 2.57489022231418 | 1.0690392440858 | 0.0160137441645123 |
| Single crust pastry | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | All - Inverse variance weighted | 0.606708419800433 | 0.252643196010117 | 0.0163305203155622 |
| Single crust pastry | Injuries to the wrist and hand (finn-b-ST19_INJURI_WRIST_HAND) | All - Inverse variance weighted | 0.459572699249473 | 0.207945783748743 | 0.0271009849686174 |
| Single crust pastry | Forearm bone mineral density (ieu-a-977) | rs4363561 | 3.42529290329499 | 1.48127295637953 | 0.0207557500194559 |
| Single crust pastry | Forearm bone mineral density (ieu-a-977) | rs728661 | 3.36374937006551 | 1.45566941038132 | 0.0208443412242756 |
| Single crust pastry | Forearm bone mineral density (ieu-a-977) | rs77000583 | -3.56910434443441 | 1.22787309186307 | 0.0036521993149966 |
| Single crust pastry | Osteomodulin (prot-a-2147) | rs144508914 | 4.79191260261073 | 2.27227753174706 | 0.034956766287896 |
| Single crust pastry | Osteomodulin (prot-a-2147) | rs145991939 | 4.16738037842738 | 1.87584339840992 | 0.0263101088473752 |
| Single crust pastry | Osteomodulin (prot-a-2147) | rs2609812 | -5.98729570692188 | 2.37620798368462 | 0.0117459884497821 |
| Single crust pastry | Osteomodulin (prot-a-2147) | rs6040055 | -4.66341720458438 | 2.21314714793835 | 0.0351051983770064 |
| Single crust pastry | Osteomodulin (prot-a-2147) | All - MR Egger | 2.82146440800678 | 1.19862044620192 | 0.0349691627969092 |
| Single crust pastry | Neck/shoulder pain for 3+ months (ukb-a-341) | All - MR Egger | -0.264803716309688 | 0.0977723016339895 | 0.0179057982250025 |
| Single crust pastry | Knee pain for 3+ months (ukb-a-353) | All - MR Egger | 0.202631227709936 | 0.0899329967582686 | 0.0421625948818714 |
| Single crust pastry | Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) | rs144508914 | -0.0291858013360719 | 0.0126118738442432 | 0.0206593499805575 |
| Single crust pastry | Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) | All - MR Egger | -0.0128478678330879 | 0.0053845067855328 | 0.0329314749917643 |
| Single crust pastry | Neck/shoulder pain for 3+ months (ukb-b-16118) | rs113141796 | -0.497814373373891 | 0.175679003618768 | 0.0046018421946311 |
| Single crust pastry | Neck/shoulder pain for 3+ months (ukb-b-16118) | rs6980762 | -0.379245774340879 | 0.188550270494849 | 0.0442855965970016 |
| Single crust pastry | Neck/shoulder pain for 3+ months (ukb-b-16118) | All - MR Egger | -0.288813661735846 | 0.0909990516961396 | 0.0073279155521768 |
| Single crust pastry | Knee pain for 3+ months (ukb-b-8906) | rs144508914 | 0.376287112160438 | 0.179173859937632 | 0.0357180383108163 |
| Single crust pastry | Knee pain for 3+ months (ukb-b-8906) | All - MR Egger | 0.188503634674785 | 0.076703791747558 | 0.0288011827947667 |
| Single crust pastry | Adhesive capsulitis of shoulder (ukb-d-M13_ADHCAPSULITIS) | rs9810988 | -0.0217711566314918 | 0.0107441892544313 | 0.0427320882392954 |
| Single crust pastry | Adhesive capsulitis of shoulder (ukb-d-M13_ADHCAPSULITIS) | All - Inverse variance weighted | 0.0070095140013486 | 0.0035545408028272 | 0.0486109059943442 |
| Single crust pastry | Shoulder lesions (ukb-d-M13_SHOULDER) | rs148305053 | 0.0906328538962846 | 0.0302233345415769 | 0.0027107111962051 |
| Single crust pastry | Shoulder lesions (ukb-d-M13_SHOULDER) | All - Inverse variance weighted | 0.0224909202072504 | 0.0075933452376275 | 0.0030572209777756 |
| Single crust pastry | Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) | rs145991939 | 0.0582988314623641 | 0.0216910582012792 | 0.0071948244051944 |
| Single crust pastry | Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) | rs77000583 | 0.054091975272362 | 0.0241420396561213 | 0.0250538196404264 |
| Single crust pastry | Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) | All - Inverse variance weighted | 0.0183754030313411 | 0.0069626384692063 | 0.008311575606071 |
| Single crust pastry | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | rs113141796 | 0.0434215716901495 | 0.0184114131438592 | 0.018353649125763 |
| Single crust pastry | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | rs77000583 | 0.0407812341378186 | 0.0170062620552578 | 0.0164842890638039 |
| Single crust pastry | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | All - Inverse variance weighted | 0.0119075393509087 | 0.0057815607952019 | 0.0394394981217296 |
| Single crust pastry | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | rs148305053 | 0.0905817166182617 | 0.0302254401942013 | 0.0027276695600677 |
| Single crust pastry | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | All - Inverse variance weighted | 0.0226628390873905 | 0.0075938574861028 | 0.0028416798408255 |
| Single crust pastry | Neck/shoulder pain for 3+ months (ukb-e-3404_CSA) | rs9810988 | 17.1506080879141 | 6.22456721153183 | 0.0058636670550786 |