ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Scotch pancake (ukb-b-2035)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Scotch pancake (👉 📊) Total body bone mineral density (age 0-15) (ebi-a-GCST005345) Weighted median 53 -1.10147151 0.547347001 0.044179635
Scotch pancake (👉 📊) Total body bone mineral density (age 30-45) (ebi-a-GCST005346) MR Egger 53 -1.81797374 0.879437363 0.043808278
Scotch pancake (👉 📊) Rheumatoid arthritis (ebi-a-GCST005569) Wald ratio 1 -9.992847685 3.765843828 0.007965042
Scotch pancake (👉 📊) Osteoarthritis of the hip or knee (ebi-a-GCST007092) Weighted median 55 -0.600081637 0.277221123 0.0304159
Scotch pancake (👉 📊) Osteoarthritis of the hip or knee (ebi-a-GCST007092) Inverse variance weighted 55 -0.483683238 0.220848994 0.028516376
Scotch pancake (👉 📊) Osteopontin levels (ebi-a-GCST90010244) Inverse variance weighted 53 2.273357899 1.012531151 0.024753841
Scotch pancake (👉 📊) Osteoarthritis (Firth correction) (ebi-a-GCST90013881) MR Egger 50 -0.913441078 0.409974859 0.030598337
Scotch pancake (👉 📊) Osteoarthritis (Firth correction) (ebi-a-GCST90013881) Weighted median 50 -0.591904792 0.297844816 0.046889984
Scotch pancake (👉 📊) Osteoarthritis (Firth correction) (ebi-a-GCST90013881) Inverse variance weighted 50 -0.517134665 0.211154518 0.014322096
Scotch pancake (👉 📊) Osteoarthritis (SPA correction) (ebi-a-GCST90013931) MR Egger 50 -0.91848755 0.409678888 0.029620701
Scotch pancake (👉 📊) Osteoarthritis (SPA correction) (ebi-a-GCST90013931) Weighted median 50 -0.596108296 0.289195729 0.039278009
Scotch pancake (👉 📊) Osteoarthritis (SPA correction) (ebi-a-GCST90013931) Inverse variance weighted 50 -0.520582955 0.210946403 0.013592929
Scotch pancake (👉 📊) Bone mineral density (ebi-a-GCST90014022) MR Egger 50 -0.28916046 0.118005926 0.017966015
Scotch pancake (👉 📊) Shoulder impingement (ebi-a-GCST90014054) MR Egger 50 -3.081906285 1.159846181 0.010668711
Scotch pancake (👉 📊) Cervical spondylosis (ebi-a-GCST90038693) MR Egger 44 0.019960362 0.009498979 0.041653114
Scotch pancake (👉 📊) Neck injury (ebi-a-GCST90038700) MR Egger 44 0.026029218 0.010066544 0.01327756
Scotch pancake (👉 📊) Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) MR Egger 53 14.35605256 6.070772209 0.021883774
Scotch pancake (👉 📊) Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) MR Egger 53 14.30045985 6.07952062 0.022558981
Scotch pancake (👉 📊) Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) Simple mode 53 -28.01287117 9.08747968 0.00327985
Scotch pancake (👉 📊) Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) Simple mode 53 -27.29355084 9.074396421 0.00404896
Scotch pancake (👉 📊) Melanocytic naevi of scalp and neck (finn-b-CD2_BENIGN_MELANOCYTIC_SCALPNECK) Weighted median 53 6.339738805 2.97047682 0.032822359
Scotch pancake (👉 📊) Melanocytic naevi of scalp and neck (finn-b-CD2_BENIGN_MELANOCYTIC_SCALPNECK) Inverse variance weighted 53 4.67623137 1.931232799 0.015462082
Scotch pancake (👉 📊) Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) Inverse variance weighted 53 -0.737607937 0.294617733 0.012293342
Scotch pancake (👉 📊) Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) Weighted median 53 -10.68577071 5.196023109 0.039731582
Scotch pancake (👉 📊) Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) Simple mode 53 -30.96032224 10.63255881 0.005281712
Scotch pancake (👉 📊) Infective bursitis (finn-b-M13_INFBURSA) MR Egger 53 -7.460153634 3.212102776 0.024233276
Scotch pancake (👉 📊) Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) MR Egger 53 -5.540350422 2.491149372 0.030602102
Scotch pancake (👉 📊) Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) Weighted median 53 -5.359959877 1.939174472 0.005709017
Scotch pancake (👉 📊) Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) Inverse variance weighted 53 -3.730330028 1.334582783 0.005187913
Scotch pancake (👉 📊) Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) Weighted mode 53 -7.10767675 3.253880035 0.033466982
Scotch pancake (👉 📊) Dislocation, sprain and strain of joints and ligaments at ankle and foot level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ANKLE_FOOT_LEVEL) Inverse variance weighted 53 -1.328397581 0.464711414 0.004255914
Scotch pancake (👉 📊) Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) Inverse variance weighted 53 -4.316112681 1.987921593 0.02991844
Scotch pancake (👉 📊) Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) MR Egger 53 4.0379236 1.417827293 0.006327593
Scotch pancake (👉 📊) Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) Inverse variance weighted 53 2.165293668 0.770506624 0.004950754
Scotch pancake (👉 📊) Injuries to the neck (finn-b-ST19_INJURI_NECK) MR Egger 53 2.819223151 1.130834245 0.015952475
Scotch pancake (👉 📊) Injuries to the neck (finn-b-ST19_INJURI_NECK) Inverse variance weighted 53 1.422630426 0.612820967 0.020262817
Scotch pancake (👉 📊) Injury of muscle and tendon at lower leg level (finn-b-ST19_INJURY_MUSCLE_TENDON_LOWER_LEG_LEVEL) MR Egger 53 -3.520596858 1.388278421 0.014320461
Scotch pancake (👉 📊) Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) MR Egger 53 1.979010003 0.926439055 0.037488719
Scotch pancake (👉 📊) Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) MR Egger 53 -2.575520707 1.264922855 0.046948934
Scotch pancake (👉 📊) Ankle and foot (finn-b-Z21_ANKLE_FOOT) Simple mode 53 -20.98884803 9.99238342 0.040553565
Scotch pancake (👉 📊) Osteocrin (prot-a-2157) MR Egger 50 -2.566956964 1.216390533 0.040069183
Scotch pancake (👉 📊) Bone morphogenetic protein 7 (prot-a-257) Inverse variance weighted 50 -1.411169601 0.625508329 0.024068347
Scotch pancake (👉 📊) Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) MR Egger 55 -0.069353316 0.033242243 0.041779299
Scotch pancake (👉 📊) Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) Weighted median 55 -0.062348654 0.023540477 0.008083256
Scotch pancake (👉 📊) Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) Inverse variance weighted 55 -0.041315126 0.017173236 0.016137727
Scotch pancake (👉 📊) Heel bone mineral density (BMD) T-score automated (left) (ukb-a-361) MR Egger 55 -0.59033156 0.199420383 0.004589466
Scotch pancake (👉 📊) Heel bone mineral density (BMD) T-score automated (left) (ukb-a-361) Inverse variance weighted 55 -0.253320091 0.103074304 0.013985118
Scotch pancake (👉 📊) Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) MR Egger 55 -0.698451684 0.198175388 0.000883683
Scotch pancake (👉 📊) Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) Weighted median 55 0.019301395 0.008509567 0.023317044
Scotch pancake (👉 📊) Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) MR Egger 55 -0.015578645 0.006258165 0.015971918
Scotch pancake (👉 📊) Heel bone mineral density (BMD) (left) (ukb-b-1096) MR Egger 55 -0.438295778 0.165379412 0.010580078
Scotch pancake (👉 📊) Heel bone mineral density (BMD) (left) (ukb-b-1096) Inverse variance weighted 55 -0.184188338 0.085561545 0.031342263
Scotch pancake (👉 📊) Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) Weighted median 44 -0.045597223 0.022688222 0.044459667
Scotch pancake (👉 📊) Operation code: knee surgery (not replacement) (ukb-b-1508) MR Egger 19 -0.10017131 0.040422018 0.023996633
Scotch pancake (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) MR Egger 55 -0.435912364 0.165438665 0.011011441
Scotch pancake (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) Inverse variance weighted 55 -0.181315721 0.085591298 0.03414208
Scotch pancake (👉 📊) Operative procedures - main OPCS: W87.9 Unspecified diagnostic endoscopic examination of knee joint (ukb-b-15942) Inverse variance weighted 5 -0.026488937 0.012902422 0.040070593
Scotch pancake (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) MR Egger 55 -0.439805857 0.164657715 0.010020756
Scotch pancake (👉 📊) Operation code: ankle surgery (ukb-b-4274) Wald ratio 1 -0.050373436 0.020753616 0.015215339
Scotch pancake (👉 📊) Heel bone mineral density (BMD) (right) (ukb-b-4657) MR Egger 55 -0.441209827 0.16468133 0.009809149
Scotch pancake (👉 📊) Operative procedures - main OPCS: W20.1 Primary open reduction of fracture of long bone and extramedullary fixation using plate NEC (ukb-b-8379) Weighted median 5 0.038049009 0.017223894 0.027168875
Scotch pancake (👉 📊) Knee pain for 3+ months (ukb-b-8906) Inverse variance weighted 55 -0.100858953 0.045976972 0.028258128
Scotch pancake (👉 📊) Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) Inverse variance weighted 47 0.008423775 0.004016964 0.035989151
Scotch pancake (👉 📊) Rheumatoid arthritis (ukb-d-M13_RHEUMA) Inverse variance weighted 49 0.00860879 0.004100168 0.035762411
Scotch pancake (👉 📊) Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) MR Egger 55 -0.035167177 0.013125564 0.009806178
Scotch pancake (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_CSA) Weighted median 33 1.559635335 0.779746228 0.045480481

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Scotch pancake Total body bone mineral density (age 0-15) (ebi-a-GCST005345) rs118133560 6.85780705153041 2.89293555469456 0.0177623277872463
Scotch pancake Total body bone mineral density (age 0-15) (ebi-a-GCST005345) rs142394936 -7.03773843628049 2.334794741894 0.0025758510194808
Scotch pancake Total body bone mineral density (age 0-15) (ebi-a-GCST005345) rs74514365 5.80637695160179 2.35475252456641 0.0136703075882419
Scotch pancake Total body bone mineral density (age 30-45) (ebi-a-GCST005346) rs10029250 5.87161218717554 2.56584678911126 0.0221158613870763
Scotch pancake Total body bone mineral density (age 30-45) (ebi-a-GCST005346) rs112651842 -8.95527513091252 3.71190660142502 0.0158400198207663
Scotch pancake Total body bone mineral density (age 30-45) (ebi-a-GCST005346) rs150204675 -6.40110255047822 3.07739992915338 0.0375222336352972
Scotch pancake Total body bone mineral density (age 30-45) (ebi-a-GCST005346) rs17599659 -8.00650497351119 3.33729085811775 0.0164352846677151
Scotch pancake Total body bone mineral density (age 30-45) (ebi-a-GCST005346) rs373496 7.41852289648608 2.33339985569764 0.0014764327384364
Scotch pancake Total body bone mineral density (age 30-45) (ebi-a-GCST005346) rs62295088 9.1178730952326 2.86527037346857 0.0014615913843589
Scotch pancake Total body bone mineral density (age 30-45) (ebi-a-GCST005346) All - MR Egger -1.81797373991131 0.879437362606078 0.0438082780974791
Scotch pancake Rheumatoid arthritis (ebi-a-GCST005569) rs115373726 -9.99284768467955 3.76584382822845 0.0079650420761466
Scotch pancake Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs142398557 -3.35827058240609 1.28458437578375 0.008941422928812
Scotch pancake Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs17069933 -3.3446461069303 1.52476513698293 0.0282678923770804
Scotch pancake Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs17599659 -3.25248675559458 1.4366812662749 0.0235809495090032
Scotch pancake Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs62295088 -2.99882111121498 1.49334006752811 0.0446294704412078
Scotch pancake Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs721970 3.18281651341995 1.35874623087518 0.0191567919889672
Scotch pancake Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs74514365 3.97490276582791 1.46417304412142 0.0066320485224526
Scotch pancake Osteoarthritis of the hip or knee (ebi-a-GCST007092) All - Inverse variance weighted -0.483683238147601 0.22084899390449 0.0285163757000102
Scotch pancake Osteopontin levels (ebi-a-GCST90010244) rs112118594 -13.9250602252751 6.68919107456773 0.0373675419726463
Scotch pancake Osteopontin levels (ebi-a-GCST90010244) rs116853849 39.7521359847975 16.3010803369694 0.0147434740991198
Scotch pancake Osteopontin levels (ebi-a-GCST90010244) rs146425143 13.197633816703 5.38190503576857 0.014197646045227
Scotch pancake Osteopontin levels (ebi-a-GCST90010244) rs147281924 90.724809918025 44.4640566126919 0.0413097212272611
Scotch pancake Osteopontin levels (ebi-a-GCST90010244) rs2038940 17.1226390682021 7.62724168751985 0.0247724971588008
Scotch pancake Osteopontin levels (ebi-a-GCST90010244) rs80174241 16.3084540976643 8.23608953800955 0.0476899306417175
Scotch pancake Osteopontin levels (ebi-a-GCST90010244) rs923526 -45.6684288020436 21.9633765588689 0.0375898691015283
Scotch pancake Osteopontin levels (ebi-a-GCST90010244) All - Inverse variance weighted 2.27335789933695 1.01253115080792 0.0247538411167042
Scotch pancake Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs142394936 -2.97238271362445 1.4559854130919 0.0412019386524307
Scotch pancake Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs146425143 -3.17539216319153 1.59199183103386 0.0460861631581125
Scotch pancake Osteoarthritis (Firth correction) (ebi-a-GCST90013881) All - Inverse variance weighted -0.517134664720618 0.211154518317789 0.0143220961354994
Scotch pancake Osteoarthritis (Firth correction) (ebi-a-GCST90013881) All - MR Egger -0.913441077694516 0.409974859359338 0.0305983365496704
Scotch pancake Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs142394936 -2.92752871241629 1.41254340679907 0.0382166927007873
Scotch pancake Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs146425143 -3.14670101701281 1.56291923169465 0.0440779843808401
Scotch pancake Osteoarthritis (SPA correction) (ebi-a-GCST90013931) All - Inverse variance weighted -0.520582954617014 0.210946402736062 0.0135929291282133
Scotch pancake Osteoarthritis (SPA correction) (ebi-a-GCST90013931) All - MR Egger -0.918487549996871 0.409678888202516 0.029620700919639
Scotch pancake Bone mineral density (ebi-a-GCST90014022) rs113672899 0.735040028947488 0.366177675255426 0.0447143636266185
Scotch pancake Bone mineral density (ebi-a-GCST90014022) rs373496 -1.9571391289664 0.363003715018191 6.98670318023439e-08
Scotch pancake Bone mineral density (ebi-a-GCST90014022) All - MR Egger -0.289160459894877 0.118005925664292 0.0179660147910224
Scotch pancake Shoulder impingement (ebi-a-GCST90014054) rs146425143 -8.98967729062623 4.22850804866169 0.0335058356509538
Scotch pancake Shoulder impingement (ebi-a-GCST90014054) rs17599659 -10.1208209037124 4.12535044048249 0.014154281768687
Scotch pancake Shoulder impingement (ebi-a-GCST90014054) rs2038940 8.19137552645824 4.12795015938869 0.0472147409281534
Scotch pancake Shoulder impingement (ebi-a-GCST90014054) rs79052771 -8.23785972974025 3.98956345652089 0.0389369668672655
Scotch pancake Shoulder impingement (ebi-a-GCST90014054) All - MR Egger -3.08190628508946 1.15984618145062 0.0106687110864703
Scotch pancake Cervical spondylosis (ebi-a-GCST90038693) rs17599659 0.10154293581826 0.0330727020582455 0.0021384777978136
Scotch pancake Cervical spondylosis (ebi-a-GCST90038693) rs7912900 -0.0760660147851655 0.0328734269461273 0.0206728873846162
Scotch pancake Cervical spondylosis (ebi-a-GCST90038693) All - MR Egger 0.0199603618951755 0.0094989793359652 0.041653114296451
Scotch pancake Neck injury (ebi-a-GCST90038700) rs17599659 0.111061946902655 0.0350488870708663 0.0015308420854774
Scotch pancake Neck injury (ebi-a-GCST90038700) rs7912900 -0.0782178038337013 0.0348375915915263 0.0247544798003553
Scotch pancake Neck injury (ebi-a-GCST90038700) All - MR Egger 0.026029218102275 0.0100665443804203 0.0132775599068441
Scotch pancake Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) rs10029250 147.665477227612 67.9810167118176 0.0298437829885586
Scotch pancake Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) rs139771590 33.0247655320741 11.2617614222309 0.0033627856217387
Scotch pancake Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) rs142442008 124.754289076394 41.6571948170039 0.0027463949891982
Scotch pancake Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) All - MR Egger 14.3560525557436 6.07077220901387 0.0218837738283396
Scotch pancake Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) rs10029250 146.312937834903 67.5275182095561 0.0302565342576341
Scotch pancake Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) rs139771590 33.3441834006139 11.3104346212465 0.0031974357805934
Scotch pancake Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) rs142442008 123.607638099568 41.4198414078066 0.0028426371388299
Scotch pancake Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) All - MR Egger 14.3004598522754 6.07952062031055 0.0225589812063505
Scotch pancake Benign neoplasm: Bones of skull and face (finn-b-CD2_BENIGN_BONE_SKULL_FACE) rs142442008 80.4661487236404 37.297915301606 0.0309752913411926
Scotch pancake Benign neoplasm: Bones of skull and face (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SKULL_FACE_EXALLC) rs142442008 79.6237112712782 37.0605618924087 0.0316759963072783
Scotch pancake Melanocytic naevi of scalp and neck (finn-b-CD2_BENIGN_MELANOCYTIC_SCALPNECK) rs139771590 18.2980807549213 6.87813143588979 0.007806475265312
Scotch pancake Melanocytic naevi of scalp and neck (finn-b-CD2_BENIGN_MELANOCYTIC_SCALPNECK) All - Inverse variance weighted 4.67623137018878 1.93123279938963 0.0154620817765474
Scotch pancake Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs116853849 7.148628630426 2.72702787628496 0.0087569660215858
Scotch pancake Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs138194402 -11.4756888942401 4.25148532116567 0.0069502475003225
Scotch pancake Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs139771590 -2.78654064364222 0.988674355004061 0.0048254391795822
Scotch pancake Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) All - Inverse variance weighted -0.737607936699581 0.294617733123112 0.0122933419627292
Scotch pancake Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) rs112118594 39.0975974998372 17.9745705170538 0.0296180005867602
Scotch pancake Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) rs138194402 147.049909282271 59.6453497303379 0.0136858680418741
Scotch pancake Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) rs189587401 -29.1658542061818 12.5237090741496 0.0198669528923527
Scotch pancake Infective bursitis (finn-b-M13_INFBURSA) rs10971422 62.8281475739103 22.4285563268614 0.0050903981939428
Scotch pancake Infective bursitis (finn-b-M13_INFBURSA) All - MR Egger -7.46015363432087 3.21210277593143 0.0242332760799132
Scotch pancake Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) rs143566154 -16.9733469041274 7.10355050827129 0.0168751198419842
Scotch pancake Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) rs189587401 -9.37136239282908 4.47591867122826 0.0362840948079392
Scotch pancake Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) rs77000583 -11.4681367566339 5.24078303815936 0.0286514902550038
Scotch pancake Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) rs80028008 -48.174908029721 22.2565938737753 0.0304242378826712
Scotch pancake Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) All - Inverse variance weighted -3.73033002807631 1.33458278315827 0.0051879131102811
Scotch pancake Artificial joint re-operation (finn-b-OPER_ARTIF_JOINT_REOP) All - MR Egger -5.5403504223397 2.49114937222175 0.0306021017068498
Scotch pancake Dislocation, sprain and strain of joints and ligaments at ankle and foot level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ANKLE_FOOT_LEVEL) rs721970 -12.2007966347765 6.12366451997171 0.0463270540626658
Scotch pancake Dislocation, sprain and strain of joints and ligaments at ankle and foot level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ANKLE_FOOT_LEVEL) rs77000583 -4.58007964316038 2.02695430682946 0.0238468938957195
Scotch pancake Dislocation, sprain and strain of joints and ligaments at ankle and foot level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ANKLE_FOOT_LEVEL) All - Inverse variance weighted -1.32839758081697 0.464711414387955 0.0042559136491202
Scotch pancake Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) rs17069933 -27.9540275113538 10.7389372550948 0.0092397551404377
Scotch pancake Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) All - Inverse variance weighted -4.31611268052625 1.98792159281698 0.0299184399115652
Scotch pancake Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) rs10971422 21.8177760550642 9.40249245333991 0.0203179121304764
Scotch pancake Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) rs117756468 -16.5215155904169 6.55217601213877 0.0116845346048527
Scotch pancake Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) rs189587401 10.6712991686313 2.7889552644485 0.0001300989642458
Scotch pancake Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) rs76137005 12.9597493264925 6.37779444594852 0.0421525287694322
Scotch pancake Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) All - Inverse variance weighted 2.16529366760905 0.770506624210863 0.0049507537568932
Scotch pancake Dislocation, sprain and strain of joints and ligaments at neck level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_NECK_LEVEL) All - MR Egger 4.03792360016892 1.41782729326767 0.0063275932064888
Scotch pancake Injuries to the neck (finn-b-ST19_INJURI_NECK) rs117756468 -14.6342380979252 5.26682090927901 0.0054598507829281
Scotch pancake Injuries to the neck (finn-b-ST19_INJURI_NECK) rs146425143 13.0574351089489 6.51404627907113 0.0450160448756136
Scotch pancake Injuries to the neck (finn-b-ST19_INJURI_NECK) rs189587401 6.65331277069706 2.21875572415342 0.0027116221905338
Scotch pancake Injuries to the neck (finn-b-ST19_INJURI_NECK) rs79052771 -28.1163596713268 13.2209198177499 0.0334486053637806
Scotch pancake Injuries to the neck (finn-b-ST19_INJURI_NECK) All - Inverse variance weighted 1.42263042649359 0.612820967106504 0.0202628166701999
Scotch pancake Injuries to the neck (finn-b-ST19_INJURI_NECK) All - MR Egger 2.81922315120725 1.13083424488351 0.015952474998208
Scotch pancake Injury of muscle and tendon at lower leg level (finn-b-ST19_INJURY_MUSCLE_TENDON_LOWER_LEG_LEVEL) rs146425143 -16.0621123115475 8.12201806327428 0.0479737187565407
Scotch pancake Injury of muscle and tendon at lower leg level (finn-b-ST19_INJURY_MUSCLE_TENDON_LOWER_LEG_LEVEL) rs80174241 -5.98282006465985 2.90872064932243 0.0397000614531505
Scotch pancake Injury of muscle and tendon at lower leg level (finn-b-ST19_INJURY_MUSCLE_TENDON_LOWER_LEG_LEVEL) All - MR Egger -3.52059685769175 1.38827842130866 0.0143204612171519
Scotch pancake Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs115373726 -8.02219150807535 3.64381469704145 0.0276941760468373
Scotch pancake Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs13172815 -12.0221673880506 6.05153513207395 0.0469633015020281
Scotch pancake Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs150204675 -12.9350425079702 6.03303223521077 0.0320299465099401
Scotch pancake Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs1791339 -5.92171783874499 2.9362874760582 0.0437230290052666
Scotch pancake Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs721970 -13.1965901053494 6.33771358373972 0.0373212826090914
Scotch pancake Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs72827495 6.52362294265488 2.77527472052926 0.0187420420433386
Scotch pancake Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs76137005 8.4859728466622 4.11427658412963 0.0391537456655714
Scotch pancake Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) rs79052771 22.395731921025 10.5572646909926 0.0338917345852268
Scotch pancake Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) All - MR Egger 1.97901000340514 0.926439055298357 0.0374887188058838
Scotch pancake Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) rs183373555 -11.4880809783043 4.96201388372586 0.0206016978511091
Scotch pancake Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) All - MR Egger -2.57552070687233 1.26492285503079 0.0469489339732806
Scotch pancake Ankle and foot (finn-b-Z21_ANKLE_FOOT) rs62280577 69.3240599364873 30.3049654860115 0.0221638633492744
Scotch pancake Ankle and foot (finn-b-Z21_ANKLE_FOOT) rs80028008 114.688326504104 49.9523591818597 0.0216785029321863
Scotch pancake Osteocrin (prot-a-2157) rs62295088 10.4169575442205 4.85639046350605 0.0319528469895733
Scotch pancake Osteocrin (prot-a-2157) All - MR Egger -2.56695696426662 1.2163905330329 0.0400691830987708
Scotch pancake Bone morphogenetic protein 7 (prot-a-257) rs113672899 9.27726767882361 4.13607329343003 0.0248959526219058
Scotch pancake Bone morphogenetic protein 7 (prot-a-257) rs115978117 -11.2038209230061 4.60352169409598 0.0149433121173366
Scotch pancake Bone morphogenetic protein 7 (prot-a-257) rs142394936 -8.98340072119215 4.26563293320634 0.0352048051621944
Scotch pancake Bone morphogenetic protein 7 (prot-a-257) All - Inverse variance weighted -1.4111696013838 0.625508328626924 0.0240683472492545
Scotch pancake Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs13172815 0.32555721855912 0.125757857691841 0.0096321518564907
Scotch pancake Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs77000583 -0.265068820778972 0.122700094471617 0.0307495748602524
Scotch pancake Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) All - Inverse variance weighted -0.0413151263148992 0.0171732361757259 0.0161377272805472
Scotch pancake Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) All - MR Egger -0.0693533155589317 0.0332422428261598 0.0417792989766659
Scotch pancake Heel bone mineral density (BMD) T-score automated (left) (ukb-a-361) rs112651842 -2.3087303631213 0.813158211005237 0.0045224783286723
Scotch pancake Heel bone mineral density (BMD) T-score automated (left) (ukb-a-361) All - Inverse variance weighted -0.253320091172512 0.103074304358277 0.0139851181173507
Scotch pancake Heel bone mineral density (BMD) T-score automated (left) (ukb-a-361) All - MR Egger -0.590331559988032 0.199420382787927 0.0045894658871118
Scotch pancake Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) rs112651842 -2.11078719203365 0.809195639110653 0.0090939891083791
Scotch pancake Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) rs150204675 -1.81080909050655 0.788688894792774 0.0216773757155829
Scotch pancake Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) All - MR Egger -0.698451683769519 0.198175388325338 0.0008836826004847
Scotch pancake Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs114092141 -0.0859502711552236 0.0432088406835158 0.0466810591546342
Scotch pancake Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs117756468 0.0895660515772248 0.0418446413232261 0.032319017407164
Scotch pancake Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs151178821 0.110029613280723 0.0463511357050422 0.0176047599239588
Scotch pancake Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs189587401 0.111663978161062 0.0461365288142804 0.0155079500124263
Scotch pancake Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs72827495 -0.109158694469315 0.0470794839831526 0.0204165012136263
Scotch pancake Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) rs116853849 -0.0454459756699735 0.0231554592928431 0.0496872910690433
Scotch pancake Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) rs2038940 0.0448729156729644 0.0227790840640688 0.04884782976921
Scotch pancake Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) rs78717230 0.0501978673661402 0.0248196004637813 0.0431237862359711
Scotch pancake Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) All - MR Egger -0.0155786448500585 0.006258164897218 0.0159719177150149
Scotch pancake Heel bone mineral density (BMD) (left) (ukb-b-1096) rs11223700 -1.74932963654068 0.619919508416119 0.0047745157607902
Scotch pancake Heel bone mineral density (BMD) (left) (ukb-b-1096) rs112651842 -1.38803674135119 0.673541076487252 0.0393216581649933
Scotch pancake Heel bone mineral density (BMD) (left) (ukb-b-1096) rs78590098 -1.20599803102362 0.605533705251094 0.0464118618964743
Scotch pancake Heel bone mineral density (BMD) (left) (ukb-b-1096) All - Inverse variance weighted -0.184188338387042 0.0855615447114371 0.0313422625069474
Scotch pancake Heel bone mineral density (BMD) (left) (ukb-b-1096) All - MR Egger -0.438295778039508 0.165379412272183 0.0105800779114918
Scotch pancake Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs142394936 -0.220359039546976 0.0998858544792852 0.0273763988420833
Scotch pancake Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs143566154 0.22673840605111 0.101914411085255 0.0260951786171547
Scotch pancake Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs17599659 -0.216580199738604 0.110016861050972 0.0489979905987296
Scotch pancake Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs721970 0.206261400439266 0.10261698246659 0.0444298834598645
Scotch pancake Operation code: knee surgery (not replacement) (ukb-b-1508) rs10971422 -0.154786403091488 0.0717972209497633 0.031092807675138
Scotch pancake Operation code: knee surgery (not replacement) (ukb-b-1508) rs2435619 -0.14278157973662 0.0675687760721978 0.0345896781023837
Scotch pancake Operation code: knee surgery (not replacement) (ukb-b-1508) All - MR Egger -0.100171309606411 0.0404220179882853 0.0239966327924214
Scotch pancake Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs11223700 -1.76373465599202 0.620096992838264 0.004451074556629
Scotch pancake Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs112651842 -1.42589063438922 0.673747102755601 0.0343143002267805
Scotch pancake Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) All - Inverse variance weighted -0.181315721263123 0.0855912978632944 0.0341420799755525
Scotch pancake Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) All - MR Egger -0.435912364361021 0.165438665029087 0.0110114413728682
Scotch pancake Operative procedures - main OPCS: W87.9 Unspecified diagnostic endoscopic examination of knee joint (ukb-b-15942) rs9573825 -0.0603302444133315 0.0305011729779593 0.0479326855283203
Scotch pancake Operative procedures - main OPCS: W87.9 Unspecified diagnostic endoscopic examination of knee joint (ukb-b-15942) All - Inverse variance weighted -0.0264889372637532 0.0129024224328373 0.04007059303737
Scotch pancake Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs78590098 -1.20139395690783 0.603839014140385 0.0466357730530492
Scotch pancake Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) All - MR Egger -0.439805856981529 0.164657714695899 0.0100207559632235
Scotch pancake Operation code: ankle surgery (ukb-b-4274) rs7912900 -0.0503734360101082 0.0207536156219522 0.0152153393964448
Scotch pancake Heel bone mineral density (BMD) (right) (ukb-b-4657) All - MR Egger -0.441209827210473 0.164681330234125 0.0098091486568775
Scotch pancake Knee pain for 3+ months (ukb-b-8906) rs76137005 -0.864512922024029 0.334112545658706 0.0096677958763534
Scotch pancake Knee pain for 3+ months (ukb-b-8906) All - Inverse variance weighted -0.100858952740307 0.0459769723566467 0.0282581284319807
Scotch pancake Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) rs13172815 -0.0661193317422434 0.0280214392621658 0.0182947485222997
Scotch pancake Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) rs142398557 0.0591771931219682 0.0256334530239728 0.0209662137948371
Scotch pancake Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) All - Inverse variance weighted 0.0084237747435411 0.0040169642174785 0.0359891509517245
Scotch pancake Rheumatoid arthritis (ukb-d-M13_RHEUMA) rs13172815 -0.0661047692245459 0.0291746288580559 0.0234617519985421
Scotch pancake Rheumatoid arthritis (ukb-d-M13_RHEUMA) rs146425143 0.0648881168537743 0.0302592707789274 0.0320004888793196
Scotch pancake Rheumatoid arthritis (ukb-d-M13_RHEUMA) rs721970 0.0611662882031046 0.0279105088783829 0.0284145730823799
Scotch pancake Rheumatoid arthritis (ukb-d-M13_RHEUMA) All - Inverse variance weighted 0.0086087895032555 0.0041001683605874 0.0357624106143589
Scotch pancake Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) rs62280577 -0.110990484705281 0.0528879122665444 0.035852323129551
Scotch pancake Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) rs78717230 -0.10913573207124 0.0519461709528426 0.0356463287414426
Scotch pancake Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) All - MR Egger -0.0351671765709827 0.0131255641499955 0.0098061782031947