ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Milk-based pudding | Total body bone mineral density (age 15-30) (ebi-a-GCST005344) | All - Inverse variance weighted | 1.58568295138094 | 0.646994922124126 | 0.0142522117117273 |
| Milk-based pudding | Heel bone mineral density (ebi-a-GCST006288) | All - MR Egger | 0.367957183954178 | 0.163840895835587 | 0.0402094820201098 |
| Milk-based pudding | Shoulder impingement (ebi-a-GCST90014054) | rs10091946 | 8.00728096638281 | 2.83867313297947 | 0.0047906594342084 |
| Milk-based pudding | Shoulder impingement (ebi-a-GCST90014054) | All - Inverse variance weighted | 1.46128026500782 | 0.61348149092109 | 0.0172213858737674 |
| Milk-based pudding | Sciatica (ebi-a-GCST90038692) | rs75406904 | 0.0491326160698102 | 0.0213326341956032 | 0.0212694567652973 |
| Milk-based pudding | Sciatica (ebi-a-GCST90038692) | rs9365376 | 0.0391090946934964 | 0.0193502022355608 | 0.0432672698488449 |
| Milk-based pudding | Sciatica (ebi-a-GCST90038692) | All - Inverse variance weighted | 0.0117581673837763 | 0.0055291107543135 | 0.0334539272934777 |
| Milk-based pudding | Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder (finn-b-CD2_BENIGN_CONNSOFT_UPPERLIMB) | rs139507267 | 10.2505462193454 | 4.52494231515325 | 0.0234916416821425 |
| Milk-based pudding | Benign neoplasm: Connective and other soft tissue of upper limb, including shoulder (finn-b-CD2_BENIGN_CONNSOFT_UPPERLIMB) | All - Inverse variance weighted | 3.29196485349429 | 1.61802357379617 | 0.0418952396174475 |
| Milk-based pudding | Cervical root disorders (finn-b-G6_CERVROOT) | rs1557279 | -33.518892466663 | 15.3995888591752 | 0.0295097106189344 |
| Milk-based pudding | Cervical root disorders (finn-b-G6_CERVROOT) | All - MR Egger | 12.0559987604013 | 5.24417727630419 | 0.036299253705115 |
| Milk-based pudding | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | rs72692576 | 7.94873031835741 | 3.78696512132761 | 0.0358194490575526 |
| Milk-based pudding | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | All - Inverse variance weighted | 3.41419239888909 | 1.68920521794093 | 0.0432608537021271 |
| Milk-based pudding | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | All - MR Egger | 6.65756348651468 | 2.99099446204252 | 0.0417774841056483 |
| Milk-based pudding | Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) | rs74702565 | 26.1162714612879 | 9.35975306183411 | 0.0052663524638182 |
| Milk-based pudding | Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) | rs75105291 | 18.6110650852784 | 7.57911840635406 | 0.0140660874718739 |
| Milk-based pudding | Other specified/unspecified disorders of synovium and tendon +Other specified/unspecified bursopathies (finn-b-M13_DISSYNOTENDNAS) | All - Inverse variance weighted | 3.27760137946711 | 1.55220377743501 | 0.0347225488314109 |
| Milk-based pudding | Other specific joint derangements/joint disorders (finn-b-M13_JOINTOTH) | rs74702565 | 4.45939602566109 | 2.06967183966089 | 0.0311900809374111 |
| Milk-based pudding | Other specific joint derangements/joint disorders (finn-b-M13_JOINTOTH) | All - MR Egger | 1.19705623201966 | 0.536978020017684 | 0.0415081480081625 |
| Milk-based pudding | Monoarthritis, not elsewhere classified (finn-b-M13_MONOARTHRITIS) | rs139507267 | 10.7528638229228 | 4.64950074530864 | 0.0207395715474211 |
| Milk-based pudding | Monoarthritis, not elsewhere classified (finn-b-M13_MONOARTHRITIS) | rs76230336 | -11.6518860334576 | 4.96592285711643 | 0.0189573434285084 |
| Milk-based pudding | Monoarthritis, not elsewhere classified (finn-b-M13_MONOARTHRITIS) | All - MR Egger | 5.76739617210697 | 2.43569540342395 | 0.0317549042167713 |
| Milk-based pudding | Osteopathies and chondropathies (finn-b-M13_OSTEOCHONDRO) | All - Inverse variance weighted | 0.770294361300951 | 0.375080206597668 | 0.0400067658017368 |
| Milk-based pudding | Other osteochondropathies (finn-b-M13_OSTEOCHONDROPATHY) | rs139507267 | 8.13713678965961 | 3.4529230392257 | 0.0184434124386864 |
| Milk-based pudding | Other osteochondropathies (finn-b-M13_OSTEOCHONDROPATHY) | rs76230336 | 10.888964924124 | 3.67589261769792 | 0.0030538566814679 |
| Milk-based pudding | Other osteochondropathies (finn-b-M13_OSTEOCHONDROPATHY) | All - Inverse variance weighted | 3.5831114999461 | 1.1653932296217 | 0.0021078900036685 |
| Milk-based pudding | Other osteochondropathies (finn-b-M13_OSTEOCHONDROPATHY) | All - MR Egger | 4.83952794839306 | 2.09578129713088 | 0.0355871721563162 |
| Milk-based pudding | Otherdisorders of bone (finn-b-M13_OTHERBONE) | rs72692576 | 2.93717089028006 | 1.34705373742472 | 0.029224804707269 |
| Milk-based pudding | Otherdisorders of bone (finn-b-M13_OTHERBONE) | rs73117244 | 7.12831255585017 | 2.95914331336156 | 0.0160002040603131 |
| Milk-based pudding | Otherdisorders of bone (finn-b-M13_OTHERBONE) | All - Inverse variance weighted | 1.95013700210504 | 0.598385151284462 | 0.0011180580352017 |
| Milk-based pudding | Other joint disorders (finn-b-M13_OTHERJOINT) | All - MR Egger | 0.907500551494031 | 0.370365125903041 | 0.0270261726575908 |
| Milk-based pudding | Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) | rs118108800 | 41.908456363947 | 16.6020136309271 | 0.011592908143476 |
| Milk-based pudding | Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) | rs1557279 | -25.2960759700922 | 10.1420800815005 | 0.012625191790602 |
| Milk-based pudding | Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) | rs72692576 | 10.982384396442 | 4.495745462507 | 0.0145722181412664 |
| Milk-based pudding | Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_LUMBAR_SPINE_PELVIS) | rs74702565 | 28.7513691128149 | 14.135645296653 | 0.0419554003137942 |
| Milk-based pudding | Injuries to the abdomen, lower back, lumbar spine and pelvis (finn-b-ST19_INJURI_ABDOMEN_LOWER_BACK_LUMBAR_SPINE_PELVIS) | All - Inverse variance weighted | -0.924750045576634 | 0.458476036278141 | 0.0436946300735087 |
| Milk-based pudding | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | rs74702565 | 31.1908792193568 | 10.8675552268104 | 0.0041035287552857 |
| Milk-based pudding | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | All - Inverse variance weighted | 5.39930795648942 | 1.57390886849151 | 0.0006024508084271 |
| Milk-based pudding | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | All - MR Egger | 6.35956373501804 | 2.79166017754949 | 0.0377914615279329 |
| Milk-based pudding | Superficial injury of neck (finn-b-ST19_SUPERF_INJURY_NECK) | rs75406904 | 17.4201817758098 | 8.66153965664569 | 0.0443031994777619 |
| Milk-based pudding | Superficial injury of neck (finn-b-ST19_SUPERF_INJURY_NECK) | All - Inverse variance weighted | 4.74156667184697 | 2.17044659940679 | 0.0289178825979236 |
| Milk-based pudding | Neck/shoulder pain for 3+ months (ukb-a-341) | All - Inverse variance weighted | 0.125909104619846 | 0.0611825010385328 | 0.0395971668755614 |
| Milk-based pudding | Diagnoses - main ICD10: M25.5 Pain in joint (ukb-b-13019) | All - Inverse variance weighted | -0.014413981371699 | 0.0071644238685164 | 0.0442322897047288 |
| Milk-based pudding | Neck/shoulder pain for 3+ months (ukb-b-16118) | rs9865095 | 0.483397031093788 | 0.217697009579974 | 0.0263845898665106 |
| Milk-based pudding | Neck/shoulder pain for 3+ months (ukb-b-16118) | All - Inverse variance weighted | 0.129053913310379 | 0.0517726248302897 | 0.0126773900741878 |
| Milk-based pudding | Fractured bone site(s): Other bones (ukb-b-17738) | rs7463703 | 0.10176716036585 | 0.0488650154182831 | 0.0372860577527067 |
| Milk-based pudding | Fractured bone site(s): Other bones (ukb-b-17738) | All - Inverse variance weighted | 0.0351492256406068 | 0.0142259046140067 | 0.0134814886814125 |
| Milk-based pudding | Non-cancer illness code, self-reported: spine arthritis/spondylitis (ukb-b-5389) | rs1557279 | 0.0435865669741127 | 0.0205764157979952 | 0.0341515386291278 |
| Milk-based pudding | Non-cancer illness code, self-reported: spine arthritis/spondylitis (ukb-b-5389) | All - Inverse variance weighted | 0.0204480193883649 | 0.0092802831524509 | 0.0275677558418269 |
| Milk-based pudding | Non-cancer illness code, self-reported: sciatica (ukb-b-8194) | rs75406904 | 0.0504407157098837 | 0.0217108806546001 | 0.020163470377327 |
| Milk-based pudding | Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) | All - MR Egger | 0.0184284269665515 | 0.0082928383389605 | 0.0420712329043483 |
| Milk-based pudding | Diagnoses - main ICD10: S72 Fracture of femur (ukb-d-S72) | rs139507267 | -0.0343918077307904 | 0.0175330692422355 | 0.0498161228613432 |
| Milk-based pudding | Diagnoses - main ICD10: S72 Fracture of femur (ukb-d-S72) | rs72692576 | -0.0443676083673189 | 0.0182799274149556 | 0.0152191499666822 |
| Milk-based pudding | Diagnoses - main ICD10: S72 Fracture of femur (ukb-d-S72) | All - MR Egger | -0.0207692692208954 | 0.0082468449091438 | 0.0236287166503947 |
| Milk-based pudding | Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) | rs118108800 | 0.0523888927561178 | 0.0260375388392829 | 0.0442144126172313 |
| Milk-based pudding | Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) | rs139719165 | -0.0649267923877732 | 0.0305875465348277 | 0.0337828168957406 |
| Milk-based pudding | Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) | rs7463703 | 0.0637327427790605 | 0.0277533284120477 | 0.0216530221863644 |