ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Green bean | Total body bone mineral density (age 30-45) (ebi-a-GCST005346) | rs115617710 | 1.71351513204339 | 0.658960219784543 | 0.0093133696699927 |
| Green bean | Total body bone mineral density (age 30-45) (ebi-a-GCST005346) | rs79842475 | 1.92427415247043 | 0.666578627979952 | 0.0038919086490846 |
| Green bean | Total body bone mineral density (age 30-45) (ebi-a-GCST005346) | All - Inverse variance weighted | 0.37847019497289 | 0.192967329524237 | 0.0498420003411211 |
| Green bean | Osteoprotegerin levels (ebi-a-GCST90010243) | rs115617710 | -4.417328358894 | 1.97518681467591 | 0.0253248997060336 |
| Green bean | Osteoprotegerin levels (ebi-a-GCST90010243) | rs146548702 | -1.66670861781455 | 0.73592958499827 | 0.0235270165941654 |
| Green bean | Osteoprotegerin levels (ebi-a-GCST90010243) | All - Inverse variance weighted | -0.825425323672198 | 0.418709844018145 | 0.0486833993167307 |
| Green bean | Osteoprotegerin levels (ebi-a-GCST90010243) | All - MR Egger | -1.57584890217551 | 0.702023473345805 | 0.0414642379952986 |
| Green bean | Spine arthritis or spondylitis (ebi-a-GCST90038657) | rs115617710 | 0.020407003555981 | 0.0085215795811941 | 0.016631962549772 |
| Green bean | Spine arthritis or spondylitis (ebi-a-GCST90038657) | rs73790412 | 0.0175077644689421 | 0.0080784926860292 | 0.0302190873673013 |
| Green bean | Spine arthritis or spondylitis (ebi-a-GCST90038657) | All - Inverse variance weighted | 0.0067266090281919 | 0.0022086102961759 | 0.0023219363822415 |
| Green bean | Osteoarthritis (ebi-a-GCST90038686) | rs117462537 | -0.0544747370898416 | 0.024388754895004 | 0.0255093657044128 |
| Green bean | Osteoarthritis (ebi-a-GCST90038686) | rs7047957 | 0.0595304349382175 | 0.0250919356137541 | 0.0176685106232341 |
| Green bean | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | rs1153592 | 13.0650173851503 | 5.65248161481892 | 0.020812026681461 |
| Green bean | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | rs7047957 | 17.2686846272917 | 5.75324570743448 | 0.0026860432669628 |
| Green bean | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | All - MR Egger | -7.78351420235598 | 3.12545176662556 | 0.0249761100269361 |
| Green bean | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | rs1153592 | 13.1450198467645 | 5.64940459706453 | 0.0199760516315283 |
| Green bean | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | rs7047957 | 17.241842112327 | 5.75324570743448 | 0.0027274948691419 |
| Green bean | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | All - MR Egger | -7.75231079818485 | 3.13173749290406 | 0.0257234911279528 |
| Green bean | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | All - Inverse variance weighted | 2.72894559973785 | 1.3128391723736 | 0.0376486592031684 |
| Green bean | Disorders of continuity of bone (finn-b-M13_BONECONTINUITY) | rs11485443 | -7.93122818341384 | 3.34603446202373 | 0.0177718941554428 |
| Green bean | Disorders of continuity of bone (finn-b-M13_BONECONTINUITY) | rs7047957 | -3.85637464992887 | 1.9460823349409 | 0.0475229972117546 |
| Green bean | Other juvenile arthritis (finn-b-M13_JUVEARTH) | rs1153592 | 6.7202067755931 | 2.51084648758423 | 0.0074402095739778 |
| Green bean | Other juvenile arthritis (finn-b-M13_JUVEARTH) | rs13002529 | -6.93257334196632 | 3.18860446404625 | 0.0296922486658723 |
| Green bean | Other juvenile arthritis (finn-b-M13_JUVEARTH) | All - Inverse variance weighted | 1.38368993778371 | 0.684333418516862 | 0.0431812182887884 |
| Green bean | Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP) | rs146548702 | -6.70326904319919 | 3.3956832268823 | 0.0483753691671712 |
| Green bean | Juvenile osteochondrosis (finn-b-M13_JUVOSTEOCHONRHIP) | All - MR Egger | -3.39862293998197 | 1.54309175538682 | 0.0436885875821004 |
| Green bean | Lower back pain or/and sciatica (finn-b-M13_LOWBACKPAINORANDSCIATICA) | rs149262767 | -1.0938660544618 | 0.554649895339976 | 0.0485897565862954 |
| Green bean | Lower back pain or/and sciatica (finn-b-M13_LOWBACKPAINORANDSCIATICA) | All - MR Egger | -0.640956191471613 | 0.277672382648812 | 0.0356462917015107 |
| Green bean | Other joint disorders (finn-b-M13_OTHERJOINT) | All - Inverse variance weighted | 0.21998440509529 | 0.0988085334541501 | 0.0259893740474598 |
| Green bean | Short Achilles tendon (acquired) (finn-b-M13_SHORTACHILLES) | All - Inverse variance weighted | 2.26304094416166 | 0.920041120530638 | 0.013904654336919 |
| Green bean | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | rs115038961 | 9.3339884754545 | 4.44365033278242 | 0.0356828843094643 |
| Green bean | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | rs17068900 | 8.01266657171154 | 3.35213665587932 | 0.0168338724425035 |
| Green bean | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | rs73790412 | 8.68666525333899 | 3.18793724825101 | 0.0064329823461795 |
| Green bean | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | rs75384405 | 14.1844114385091 | 5.79292409820194 | 0.0143422408090241 |
| Green bean | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | All - Inverse variance weighted | 3.329405016032 | 1.25175909042644 | 0.007819148031687 |
| Green bean | Osteomyelitis (ieu-b-4975) | rs9899110 | 1.92799003626506 | 0.956108282354665 | 0.0437479711650522 |
| Green bean | Osteomyelitis (ieu-b-4975) | All - Inverse variance weighted | 0.617497358616773 | 0.225887552069073 | 0.0062636710728431 |
| Green bean | Bone morphogenetic protein 7 (prot-a-257) | rs117462537 | -2.51098445100749 | 1.09003976167767 | 0.0212467132390134 |
| Green bean | Bone morphogenetic protein 7 (prot-a-257) | All - Inverse variance weighted | -0.640997068084718 | 0.276356400044742 | 0.0203702149084794 |
| Green bean | Bone morphogenetic protein receptor type-1A (prot-a-259) | rs149262767 | 2.22728105798262 | 1.01669737337102 | 0.028473357956193 |
| Green bean | Bone morphogenetic protein receptor type-1A (prot-a-259) | All - Inverse variance weighted | 0.645772172048343 | 0.272916344771808 | 0.0179721745769607 |
| Green bean | Bone morphogenetic protein receptor type-1A (prot-a-259) | All - MR Egger | 1.27677450931359 | 0.566910885705203 | 0.0408869457022262 |
| Green bean | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | rs1153592 | -0.0326339271977599 | 0.0132980091695129 | 0.0141258881069344 |
| Green bean | Non-cancer illness code self-reported: osteoporosis (ukb-a-87) | All - Inverse variance weighted | -0.0064857652081571 | 0.0032221889249119 | 0.0441309923237548 |
| Green bean | Diagnoses - secondary ICD10: M06.99 Rheumatoid arthritis, unspecified (Site unspecified) (ukb-b-11874) | rs7047957 | -0.0109842702862307 | 0.0054785573042957 | 0.0449676740755499 |
| Green bean | Diagnoses - secondary ICD10: M06.99 Rheumatoid arthritis, unspecified (Site unspecified) (ukb-b-11874) | All - Inverse variance weighted | -0.0087098303317142 | 0.0036733933821545 | 0.0177372269823292 |
| Green bean | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | rs7047957 | 0.0653472079310684 | 0.026344496837057 | 0.013120268470953 |
| Green bean | Non-cancer illness code, self-reported: spine arthritis/spondylitis (ukb-b-5389) | rs73790412 | 0.0214035933856265 | 0.0083365751536993 | 0.0102454755809119 |
| Green bean | Non-cancer illness code, self-reported: spine arthritis/spondylitis (ukb-b-5389) | All - Inverse variance weighted | 0.0088988677659132 | 0.0030551800466192 | 0.003583018198204 |
| Green bean | Operation code: reduction or fixation of bone fracture (ukb-b-847) | rs7047957 | 0.052247165877795 | 0.0199669837065934 | 0.0088790071143292 |
| Green bean | Operation code: reduction or fixation of bone fracture (ukb-b-847) | All - Inverse variance weighted | 0.0159627976495802 | 0.0066400946585476 | 0.0162167058743806 |
| Green bean | Fractured bone site(s): Wrist (ukb-b-9571) | All - Inverse variance weighted | 0.008520847352313 | 0.0043144072457478 | 0.048270961419482 |
| Green bean | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | rs117462537 | 0.0198288142101547 | 0.0091674113502159 | 0.0305436676369953 |
| Green bean | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | rs79842475 | 0.0257953980920759 | 0.0097179303362449 | 0.0079446584542472 |
| Green bean | Diagnoses - main ICD10: M65 Synovitis and tenosynovitis (ukb-d-M65) | All - Inverse variance weighted | 0.0047071868084626 | 0.0022488458795814 | 0.0363351690671054 |
| Green bean | Diagnoses - main ICD10: S02 Fracture of skull and facial bones (ukb-d-S02) | rs73790412 | -0.0131770722917108 | 0.0062112306550773 | 0.0338804726126381 |
| Green bean | Diagnoses - main ICD10: S02 Fracture of skull and facial bones (ukb-d-S02) | All - MR Egger | 0.0108175887566262 | 0.0035917811061833 | 0.0100098936429822 |
| Green bean | Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) | rs149262767 | 0.0161592182812605 | 0.0076543518313092 | 0.0347624136774696 |
| Green bean | Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) | rs7047957 | -0.0186197131429901 | 0.007800748011417 | 0.0169904741429925 |
| Green bean | Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) | rs75384405 | 0.0200609686139453 | 0.00661584942423 | 0.0024273087859891 |
| Green bean | Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) | All - Inverse variance weighted | 0.0050132499503682 | 0.0022669861329953 | 0.0270070262674884 |
| Green bean | Diagnoses - main ICD10: S61 Open wound of wrist and hand (ukb-d-S61) | All - MR Egger | 0.0126463244489471 | 0.0043194580694157 | 0.0110203858893088 |
| Green bean | Heel bone mineral density (BMD) (ukb-e-3148_AFR) | rs11485443 | -5.94613767455172 | 2.56052318704454 | 0.0202202619933257 |
| Green bean | Heel bone mineral density (BMD) (ukb-e-3148_AFR) | All - Inverse variance weighted | -1.18055889916724 | 0.57547489341502 | 0.0402229870227175 |
| Green bean | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_AFR) | rs11485443 | -5.99180693472493 | 2.56509011306187 | 0.0194961910017894 |
| Green bean | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_AFR) | All - Inverse variance weighted | -1.26070826463282 | 0.576309773763908 | 0.0287021671933129 |