ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| White pasta | Bone disorder (ebi-a-GCST90038652) | rs6736155 | -0.0399952246986889 | 0.016838456401153 | 0.0175379675870984 |
| White pasta | Bone disorder (ebi-a-GCST90038652) | All - Inverse variance weighted | -0.0158708431274896 | 0.0069308057018004 | 0.02202718827544 |
| White pasta | Osteoporosis (ebi-a-GCST90038656) | rs6736155 | -0.03009045389585 | 0.0143613380532688 | 0.0361496386816617 |
| White pasta | Osteoporosis (ebi-a-GCST90038656) | All - Inverse variance weighted | -0.0119684709832139 | 0.0058165048741206 | 0.0396214356318986 |
| White pasta | Malignant neoplasm of bone and articular cartilage (finn-b-C3_BONE_CARTILAGE) | All - Inverse variance weighted | -5.48528346930884 | 2.68207691781916 | 0.040838827881639 |
| White pasta | Malignant neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-C3_BONE_CARTILAGE_EXALLC) | All - Inverse variance weighted | -5.51132843874028 | 2.68158143295823 | 0.0398545688344318 |
| White pasta | Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) | rs10804975 | -5.98765734436989 | 2.53465249546946 | 0.0181610151852828 |
| White pasta | Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) | All - MR Egger | 3.98958902954693 | 1.64217683919352 | 0.0412375130222105 |
| White pasta | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | All - Inverse variance weighted | -3.02978824917926 | 1.43811472952988 | 0.0351368408817866 |
| White pasta | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs6736155 | -14.5733199071239 | 7.3878755791783 | 0.0485412064232367 |
| White pasta | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs76980069 | -11.7625557423788 | 4.95650266832371 | 0.0176367968294738 |
| White pasta | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | All - Inverse variance weighted | -5.29018155457471 | 2.22236367212591 | 0.017292437721565 |
| White pasta | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | All - Inverse variance weighted | -2.80074280227767 | 1.20399512023314 | 0.0200074694270455 |
| White pasta | Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) | All - Inverse variance weighted | -0.919863766077194 | 0.405975203323116 | 0.0234628543004263 |
| White pasta | Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) | All - MR Egger | -2.12248441869751 | 0.87037732713385 | 0.0406544797186937 |
| White pasta | Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) | All - Inverse variance weighted | -0.939702170655773 | 0.395315195443736 | 0.0174495459791862 |
| White pasta | Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) | All - MR Egger | -2.09820920673461 | 0.847811443661473 | 0.0384186399758841 |
| White pasta | Spinal osteochondrosis (finn-b-M13_SPINALOSTEOCHON) | rs10804975 | 14.7364940980555 | 7.13865896067003 | 0.038987151928147 |
| White pasta | Spinal osteochondrosis (finn-b-M13_SPINALOSTEOCHON) | rs2993494 | 11.3087952098423 | 5.20025260597366 | 0.0296554043513086 |
| White pasta | Spinal osteochondrosis (finn-b-M13_SPINALOSTEOCHON) | All - Inverse variance weighted | 5.11236893073732 | 2.16514920258863 | 0.0182154808999834 |
| White pasta | Dislocation, sprain and strain of joints and ligaments of elbow (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ELBOW) | rs112811367 | -7.75647173815012 | 3.65448048692834 | 0.0337995166173058 |
| White pasta | Dislocation, sprain and strain of joints and ligaments of elbow (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ELBOW) | All - Inverse variance weighted | -2.27531160727451 | 1.13385828282343 | 0.0447817860030379 |
| White pasta | Fracture of skull and facial bones (finn-b-ST19_FRACT_SKULL_FACIAL_BONES) | rs11100431 | 5.58014954800789 | 1.64215829555661 | 0.0006786596765027 |
| White pasta | Fracture of skull and facial bones (finn-b-ST19_FRACT_SKULL_FACIAL_BONES) | rs62353824 | -3.35415558840888 | 1.69850387519892 | 0.048294182074106 |
| White pasta | Fracture of skull and facial bones (finn-b-ST19_FRACT_SKULL_FACIAL_BONES) | All - MR Egger | -3.23569431068705 | 1.35315100860214 | 0.0437717770146132 |
| White pasta | Fractured/broken bones in last 5 years (ukb-a-308) | rs1359354 | 0.0934937666339824 | 0.0454700658355512 | 0.0397670200111428 |
| White pasta | Fractured/broken bones in last 5 years (ukb-a-308) | rs76980069 | 0.0930223944245437 | 0.0420586300168141 | 0.0269852266243273 |
| White pasta | Fractured/broken bones in last 5 years (ukb-a-308) | All - Inverse variance weighted | 0.0289965223287752 | 0.0143384237941058 | 0.0431458878810803 |
| White pasta | Fractured bone site(s): Other bones (ukb-a-441) | rs76980069 | 0.0700392328873943 | 0.0316675195555231 | 0.0269870077572016 |
| White pasta | Fractured bone site(s): Other bones (ukb-a-441) | All - Inverse variance weighted | 0.0268651625972129 | 0.0107104250530358 | 0.0121307100299468 |
| White pasta | Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified (ukb-b-11045) | rs10804975 | 0.0166280550521624 | 0.0073686143899691 | 0.0240327424014251 |
| White pasta | Diagnoses - secondary ICD10: M13.9 Arthritis, unspecified (ukb-b-11045) | All - Inverse variance weighted | 0.0082364711479327 | 0.0041752438823474 | 0.0485306382226274 |
| White pasta | Diagnoses - secondary ICD10: M06.99 Rheumatoid arthritis, unspecified (Site unspecified) (ukb-b-11874) | All - Inverse variance weighted | 0.0097883301965989 | 0.0042394820284074 | 0.0209518786585577 |
| White pasta | Fractured heel (ukb-b-18389) | rs145308424 | -0.0198981634686583 | 0.0093317548975692 | 0.032981641819033 |
| White pasta | Fractured heel (ukb-b-18389) | rs79841628 | 0.0293365607087392 | 0.0097149243026298 | 0.0025299045634432 |
| White pasta | Fractured bone site(s): Arm (ukb-b-19255) | rs11100431 | 0.0325349822232379 | 0.0123988265742665 | 0.0086894292793228 |
| White pasta | Fractured bone site(s): Arm (ukb-b-19255) | All - Inverse variance weighted | 0.0161490739219695 | 0.0064997276134332 | 0.0129705443604017 |
| White pasta | Impingement syndrome of shoulder (ukb-d-M13_IMPINGEMENT) | rs1359354 | 0.0283563524303124 | 0.0144313209132932 | 0.0494238076158812 |
| White pasta | Impingement syndrome of shoulder (ukb-d-M13_IMPINGEMENT) | All - Inverse variance weighted | 0.0110930141610502 | 0.0045091039407578 | 0.0138883926755304 |
| White pasta | Ankle spacing width (left) (ukb-e-4100_CSA) | rs6736155 | -1.25888015723891 | 0.574074266316478 | 0.0283155012938273 |
| White pasta | Ankle spacing width (left) (ukb-e-4100_CSA) | All - Inverse variance weighted | -1.09186446489686 | 0.383025884234651 | 0.0043632928985905 |
| White pasta | Heel bone mineral density (BMD) (right) (ukb-e-4124_AFR) | rs10804975 | -5.04297889014057 | 2.02037517754812 | 0.0125581143377088 |
| White pasta | Heel bone mineral density (BMD) (right) (ukb-e-4124_AFR) | All - Inverse variance weighted | -1.69264378389367 | 0.743406951492311 | 0.0227937650027232 |
| White pasta | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) | rs10804975 | -5.05155017877259 | 1.98547778811775 | 0.0109512939127093 |
| White pasta | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) | All - Inverse variance weighted | -1.674200215129 | 0.792625468161907 | 0.0346674920482499 |
| White pasta | M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_CSA) | All - Inverse variance weighted | -2.84433506237858 | 1.34493335081125 | 0.0344425585142048 |