ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Leek | Total body bone mineral density (age 30-45) (ebi-a-GCST005346) | rs117166126 | -3.20893852150483 | 1.25567159537146 | 0.0106018435684866 |
| Leek | Total body bone mineral density (age 30-45) (ebi-a-GCST005346) | rs3862773 | 2.6743989640223 | 1.25978266989471 | 0.0337618110519225 |
| Leek | Total body bone mineral density (age 30-45) (ebi-a-GCST005346) | All - MR Egger | -1.6169651694914 | 0.685624028408527 | 0.0379218762816517 |
| Leek | Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) | rs17111396 | 11.3309394343559 | 3.34504975890017 | 0.0007056474850483 |
| Leek | Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) | All - Inverse variance weighted | 2.69955820468025 | 0.805063371260892 | 0.0007987589489043 |
| Leek | Osteoarthritis (Firth correction) (ebi-a-GCST90013881) | rs112013285 | 1.36948090866054 | 0.581261499928872 | 0.0184704526101627 |
| Leek | Osteoarthritis (Firth correction) (ebi-a-GCST90013881) | All - MR Egger | 0.969488420175789 | 0.363508808198417 | 0.0284932118709652 |
| Leek | Osteoarthritis (SPA correction) (ebi-a-GCST90013931) | rs112013285 | 1.38564202543335 | 0.593749635616956 | 0.0196106859059568 |
| Leek | Osteoarthritis (SPA correction) (ebi-a-GCST90013931) | All - MR Egger | 0.965386109170764 | 0.364164917194538 | 0.0292123245625236 |
| Leek | Neck circumference (ebi-a-GCST90017134) | rs12766168 | -9.88467874794069 | 4.73396669944195 | 0.036794856883592 |
| Leek | Neck circumference (ebi-a-GCST90017134) | rs3862773 | -11.2183998648725 | 5.47547998423512 | 0.0404774511634766 |
| Leek | Neck circumference (ebi-a-GCST90017134) | All - Inverse variance weighted | -5.33139628923974 | 1.66377004382017 | 0.0013534103068107 |
| Leek | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | rs12766168 | -9.88467874794069 | 4.73396669944195 | 0.036794856883592 |
| Leek | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | rs3862773 | -11.2183998648725 | 5.47547998423512 | 0.0404774511634766 |
| Leek | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | All - Inverse variance weighted | -5.33139628923974 | 1.66377004382017 | 0.0013534103068107 |
| Leek | Carcinoma in situ of skin of upper limb, including shoulder (finn-b-CD2_INSITU_SKIN_UPPERLIMB) | rs9814238 | -15.451053746201 | 7.171893548828 | 0.0312096219496762 |
| Leek | Carcinoma in situ of skin of upper limb, including shoulder (finn-b-CD2_INSITU_SKIN_UPPERLIMB) | All - MR Egger | -13.7907008496049 | 5.10170989462408 | 0.0221929352059527 |
| Leek | Bone morphogenetic protein receptor type-1A (prot-a-259) | rs146174254 | 4.66200144211245 | 1.65621917899047 | 0.0048800658015045 |
| Leek | Bone morphogenetic protein receptor type-1A (prot-a-259) | All - Inverse variance weighted | 1.15453993447664 | 0.530957168158523 | 0.0296713395648377 |
| Leek | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) | rs112013285 | 0.148166657727136 | 0.0748199073242741 | 0.0476686352007328 |
| Leek | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) | rs1881162 | -0.166193484189113 | 0.0767556980281264 | 0.0303703311286214 |
| Leek | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | rs149543730 | 0.0918479834112163 | 0.0433263819555624 | 0.0340137273414008 |
| Leek | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | rs1881162 | -0.0908642612874174 | 0.0428622711499342 | 0.0340134311522374 |
| Leek | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | All - MR Egger | 0.0635959854579035 | 0.0252261234475254 | 0.0284230509233295 |
| Leek | Fractured bone site(s): Ankle (ukb-b-15582) | All - Inverse variance weighted | -0.0176373673519399 | 0.0083584942821172 | 0.0348486247591579 |
| Leek | Diagnoses - secondary ICD10: M81.99 Osteoporosis, unspecified (Site unspecified) (ukb-b-17796) | rs17111396 | -0.0231899729831401 | 0.0107927225471085 | 0.0316607607852213 |
| Leek | Diagnoses - secondary ICD10: M81.99 Osteoporosis, unspecified (Site unspecified) (ukb-b-17796) | All - Inverse variance weighted | -0.0136189829077029 | 0.0054193199646353 | 0.0119694819410402 |
| Leek | Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC (ukb-b-5602) | rs3862773 | 0.0252756038511345 | 0.0118312595011542 | 0.0326516355168185 |
| Leek | Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC (ukb-b-5602) | All - Inverse variance weighted | 0.0142479967115735 | 0.0057637324265014 | 0.0134356246001267 |
| Leek | Fractured heel (left) (ukb-b-8221) | All - Inverse variance weighted | -0.019641955214158 | 0.0074808671960637 | 0.0086489933921382 |
| Leek | Heel bone mineral density (BMD) (ukb-e-3148_EAS) | rs73181706 | -7.81806214150424 | 3.44111154395533 | 0.0230890254357506 |
| Leek | Heel bone mineral density (BMD) (ukb-e-3148_EAS) | All - Inverse variance weighted | -2.83856267469955 | 1.26107513609394 | 0.0243914371729265 |
| Leek | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA) | rs73181706 | 2.84065213205629 | 1.42972923355229 | 0.0469394401964959 |
| Leek | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA) | All - Inverse variance weighted | 1.04030616003195 | 0.49164634132322 | 0.0343478346937741 |
| Leek | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_EAS) | rs73181706 | -7.55387791106395 | 3.4961872394539 | 0.0307259028862336 |
| Leek | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_EAS) | All - Inverse variance weighted | -2.8032224991397 | 1.2806977750863 | 0.0286096078250155 |