ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Coleslaw | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | rs72982434 | -2.92600733126947 | 1.260813143611 | 0.0203014014978361 |
| Coleslaw | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | rs78622406 | -2.59706473699464 | 1.12399244674685 | 0.0208565436609472 |
| Coleslaw | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | All - Inverse variance weighted | -0.532533142799292 | 0.242890652615894 | 0.0283447929935176 |
| Coleslaw | Knee osteoarthritis (ebi-a-GCST007090) | rs78622406 | -1.90642660483988 | 0.636230256484567 | 0.0027315083832017 |
| Coleslaw | Knee osteoarthritis (ebi-a-GCST007090) | All - MR Egger | -0.790088759400377 | 0.309705216908135 | 0.0206630443390337 |
| Coleslaw | Osteoarthritis of the hip or knee (ebi-a-GCST007092) | rs78622406 | -1.33132879292856 | 0.520757861179539 | 0.0105724464713831 |
| Coleslaw | Osteoarthritis of the hip or knee (ebi-a-GCST007092) | All - MR Egger | -0.554515786035388 | 0.219689979327494 | 0.0218426915323821 |
| Coleslaw | Shoulder impingement (ebi-a-GCST90014054) | rs6666162 | -3.50156531921758 | 1.46178709268841 | 0.0166022262472153 |
| Coleslaw | Shoulder impingement (ebi-a-GCST90014054) | All - Inverse variance weighted | -1.01636987633402 | 0.364847294882426 | 0.0053405610743142 |
| Coleslaw | Pain in joint (finn-b-JOINTPAIN) | rs1011059 | -1.81468579138635 | 0.9214466712739 | 0.0489085807934166 |
| Coleslaw | Pain in joint (finn-b-JOINTPAIN) | rs117635624 | 1.64846154342454 | 0.817778867432723 | 0.0438230807306812 |
| Coleslaw | Pain in joint (finn-b-JOINTPAIN) | All - MR Egger | 1.25911960879251 | 0.432932299879191 | 0.0097877349366454 |
| Coleslaw | Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) | rs6666162 | 22.7867461673577 | 9.66076784284673 | 0.0183396216959961 |
| Coleslaw | Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) | rs72870413 | -16.5083021403206 | 7.70278521440984 | 0.0321002427451138 |
| Coleslaw | Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) | All - MR Egger | -11.8880667912838 | 5.26944531420051 | 0.037531002639002 |
| Coleslaw | Gluteal tendinitis (finn-b-M13_GLUTEALTEND) | rs1011059 | 12.016416794776 | 5.17138437959842 | 0.0201449917615769 |
| Coleslaw | Gluteal tendinitis (finn-b-M13_GLUTEALTEND) | All - Inverse variance weighted | 3.18962108948828 | 1.21190598933319 | 0.0084907671838586 |
| Coleslaw | Other specific joint derangements/joint disorders (finn-b-M13_JOINTOTH) | rs1011059 | -1.8428933425478 | 0.836824017789562 | 0.0276478522520561 |
| Coleslaw | Other specific joint derangements/joint disorders (finn-b-M13_JOINTOTH) | rs117635624 | 1.94363616421387 | 0.754872800707129 | 0.0100302029567951 |
| Coleslaw | Other specific joint derangements/joint disorders (finn-b-M13_JOINTOTH) | All - MR Egger | 1.26165438742931 | 0.394960097933825 | 0.0053113401509923 |
| Coleslaw | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | rs117139461 | 7.14906097651459 | 3.47414684817193 | 0.0396103977648107 |
| Coleslaw | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | rs143102879 | 15.1084326675428 | 6.74052308399761 | 0.0249980237508607 |
| Coleslaw | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | All - Inverse variance weighted | 2.49229442239998 | 0.899451847999956 | 0.0055900962737447 |
| Coleslaw | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | rs2355174 | -5.71388709206905 | 2.77767208249306 | 0.0396787595561232 |
| Coleslaw | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | All - MR Egger | 2.73315359712718 | 1.14737437513914 | 0.0291626731176242 |
| Coleslaw | Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS) | All - Inverse variance weighted | -0.702756248297944 | 0.358406545028851 | 0.049904736716047 |
| Coleslaw | Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) | All - Inverse variance weighted | -0.751648126526728 | 0.363440219772331 | 0.0386261178578756 |
| Coleslaw | Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) | All - Inverse variance weighted | -0.753827427672217 | 0.355528926583704 | 0.0339808853248414 |
| Coleslaw | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | rs74510205 | -7.10359408033827 | 2.3020906741837 | 0.0020306384450003 |
| Coleslaw | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | rs75768484 | -2.73705456552574 | 1.15570139707248 | 0.017869748801118 |
| Coleslaw | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | All - MR Egger | -1.58983376656773 | 0.734576522393656 | 0.0449673264434397 |
| Coleslaw | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | rs2355174 | -26.9649810382659 | 11.7892520578872 | 0.0221811644908905 |
| Coleslaw | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | rs75768484 | 19.8098587012948 | 7.94086850644225 | 0.0126073770196467 |
| Coleslaw | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | All - MR Egger | 11.9362287011292 | 4.81146465185814 | 0.0238670483234446 |
| Coleslaw | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | rs114143440 | 35.1115312828681 | 14.8921165105208 | 0.0183872558132867 |
| Coleslaw | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | rs143102879 | 49.5735888776623 | 21.3680171619139 | 0.0203414113632889 |
| Coleslaw | Other and unspecified injuries of neck (finn-b-ST19_OTHER_UNSPE_INJURI_NECK) | rs72870413 | 15.5015489296355 | 7.26577672133357 | 0.0328835704366888 |
| Coleslaw | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | rs2355174 | -0.0303614778737491 | 0.014549167332547 | 0.0369045048806593 |
| Coleslaw | Non-cancer illness code self-reported: arthritis (nos) (ukb-a-113) | All - MR Egger | 0.0144601790119406 | 0.0065044244599423 | 0.0400565543363485 |
| Coleslaw | Knee pain for 3+ months (ukb-a-353) | rs117635624 | 0.44275225332757 | 0.137499919351197 | 0.001281824243104 |
| Coleslaw | Knee pain for 3+ months (ukb-a-353) | All - Inverse variance weighted | 0.0833741808014611 | 0.0367309637481846 | 0.023216020202089 |
| Coleslaw | Diagnoses - main ICD10: S66 Injury of muscle and tendon at wrist and hand level (ukb-a-591) | All - MR Egger | -0.0066165128957383 | 0.0028419960846599 | 0.032506276443294 |
| Coleslaw | Non-cancer illness code self-reported: bone disorder (ukb-a-84) | rs75768484 | 0.0177000405442785 | 0.0074133255528736 | 0.0169588851122222 |
| Coleslaw | Non-cancer illness code self-reported: bone disorder (ukb-a-84) | All - Inverse variance weighted | -0.0039931161675694 | 0.0018135083803288 | 0.0276742405759253 |
| Coleslaw | Non-cancer illness code self-reported: joint disorder (ukb-a-86) | All - Inverse variance weighted | -0.0073762976066021 | 0.0025433923572533 | 0.0037294750790428 |
| Coleslaw | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | All - MR Egger | -0.0401539044411299 | 0.0161843918727265 | 0.0238554778263828 |
| Coleslaw | Operation code: knee surgery (not replacement) (ukb-b-1508) | rs1011059 | -0.0517406409695876 | 0.0253665336210504 | 0.0413781627696605 |
| Coleslaw | Operation code: knee surgery (not replacement) (ukb-b-1508) | rs78622406 | -0.052734205187654 | 0.0254363045210839 | 0.0381549187982409 |
| Coleslaw | Operation code: knee surgery (not replacement) (ukb-b-1508) | All - MR Egger | -0.0507647570900904 | 0.0222841654529046 | 0.0487164692442811 |
| Coleslaw | Operative procedures - main OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-16039) | All - Inverse variance weighted | -0.0135390534980893 | 0.0058447863269222 | 0.0205346613486299 |
| Coleslaw | Operative procedures - secondary OPCS: Z84.1 Sacroiliac joint (ukb-b-16715) | rs6666162 | -0.0144838628732569 | 0.0061328848474709 | 0.0181927268295614 |
| Coleslaw | Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy (ukb-b-18279) | rs10486318 | 0.0188113060662315 | 0.009529263229335 | 0.0483752944147124 |
| Coleslaw | Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy (ukb-b-18279) | All - Inverse variance weighted | 0.0111589734405439 | 0.0047005135794323 | 0.0175970148132735 |
| Coleslaw | Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC (ukb-b-5602) | rs6666162 | 0.0221167058992221 | 0.0095199488582728 | 0.0201686323839608 |
| Coleslaw | Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC (ukb-b-5602) | All - Inverse variance weighted | 0.013917503258365 | 0.0049161493674089 | 0.0046406132583448 |
| Coleslaw | Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure (ukb-b-8566) | All - Inverse variance weighted | 0.0123573182012784 | 0.004414228359416 | 0.0051193097811575 |
| Coleslaw | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | rs78622406 | -0.0626143403129981 | 0.0284949644978989 | 0.0279931300545218 |
| Coleslaw | Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) | All - MR Egger | -0.0283868146587613 | 0.0130058974679201 | 0.0433816345888468 |
| Coleslaw | Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) | rs117309229 | -0.0204755207353189 | 0.0096436318255202 | 0.0337356920185491 |
| Coleslaw | Diagnoses - main ICD10: M06 Other rheumatoid arthritis (ukb-d-M06) | rs78622406 | 0.0211106406680191 | 0.0102470882843066 | 0.039383254300136 |
| Coleslaw | Rheumatoid arthritis (ukb-d-M13_RHEUMA) | rs78622406 | 0.0220954617084481 | 0.0106687663019852 | 0.0383548834449805 |
| Coleslaw | Shoulder lesions (ukb-d-M13_SHOULDER) | All - Inverse variance weighted | 0.0138971470302934 | 0.004989595539883 | 0.0053490565255275 |
| Coleslaw | Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) | rs12576200 | -0.0422487594967984 | 0.0201824208857502 | 0.0363184140807506 |
| Coleslaw | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | All - Inverse variance weighted | 0.0088037723850588 | 0.0041249449041912 | 0.0328201654172584 |
| Coleslaw | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | All - Inverse variance weighted | 0.0139853298678167 | 0.0050051526698508 | 0.0052030467104938 |
| Coleslaw | Heel bone mineral density (BMD) (ukb-e-3148_CSA) | rs1011059 | 3.66463102172452 | 1.84853485278009 | 0.0474287105203745 |
| Coleslaw | Heel bone mineral density (BMD) (ukb-e-3148_CSA) | rs72841588 | 2.83826088830696 | 0.920717283890748 | 0.0020515750235955 |
| Coleslaw | Heel bone mineral density (BMD) (ukb-e-3148_CSA) | rs74510205 | -3.48790227859995 | 1.53103124265915 | 0.022718285817114 |
| Coleslaw | Fractured bone site(s) (ukb-e-6151_p7_CSA) | rs72841588 | -6.71375997499852 | 3.19388541346739 | 0.0355474387873814 |
| Coleslaw | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_CSA) | rs1011059 | 3.77840147807568 | 1.84195309084242 | 0.0402375765430452 |
| Coleslaw | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_CSA) | rs72841588 | 2.80323726082904 | 0.917619039921547 | 0.0022513323863529 |
| Coleslaw | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_CSA) | rs74510205 | -3.50481559783885 | 1.52595724688748 | 0.0216302940299291 |