ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
Intake (exposure) | Outcome | SNP | b | se | P-value |
---|---|---|---|---|---|
Orange juice | Rheumatoid Arthritis (bbj-a-74) | All - Inverse variance weighted | -0.49921528226795 | 0.249045859861051 | 0.0450152996494667 |
Orange juice | Shoulder impingement (ebi-a-GCST90014054) | rs4961673 | -3.83429161493553 | 1.04130053077149 | 0.0002312169985517 |
Orange juice | Shoulder impingement (ebi-a-GCST90014054) | rs62352893 | -1.92471216340319 | 0.968952921478708 | 0.046990749556256 |
Orange juice | Shoulder impingement (ebi-a-GCST90014054) | All - Inverse variance weighted | -1.15001648541973 | 0.3965454586503 | 0.0037305863121702 |
Orange juice | Malignant neoplasm of bone and articular cartilage (finn-b-C3_BONE_CARTILAGE) | All - Inverse variance weighted | -3.68106018225844 | 1.79937791081066 | 0.0407819134424072 |
Orange juice | Malignant neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-C3_BONE_CARTILAGE_EXALLC) | All - Inverse variance weighted | -3.74923085330876 | 1.79830441047127 | 0.0370811056777089 |
Orange juice | Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) | All - Inverse variance weighted | -1.54249370601172 | 0.696661338382987 | 0.0268203372641996 |
Orange juice | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs6576250 | -3.16125208162804 | 1.59121059019447 | 0.0469560697946107 |
Orange juice | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | All - Inverse variance weighted | -1.3352768820884 | 0.524086262857955 | 0.0108398729747202 |
Orange juice | Recurrent dislocation and subluxation of joint (finn-b-M13_RECUDISLOCATIO) | rs55690725 | -4.00956318175026 | 2.00063090435158 | 0.0450540613895147 |
Orange juice | Recurrent dislocation and subluxation of joint (finn-b-M13_RECUDISLOCATIO) | rs6576250 | -4.14561517400999 | 1.71822518275989 | 0.0158335002620307 |
Orange juice | Recurrent dislocation and subluxation of joint (finn-b-M13_RECUDISLOCATIO) | All - Inverse variance weighted | -1.46380930222693 | 0.566369584691794 | 0.0097506768628387 |
Orange juice | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | rs117787888 | 1.64055977534256 | 0.640265914694784 | 0.0103978453669104 |
Orange juice | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | rs4961673 | 1.47057050903437 | 0.709168565149086 | 0.0381114198903487 |
Orange juice | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | All - Inverse variance weighted | 0.488067621021484 | 0.224836179954169 | 0.0299485672430803 |
Orange juice | Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) | rs13216626 | 11.3277339562226 | 4.87933886644563 | 0.020256021028359 |
Orange juice | Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) | All - MR Egger | 11.4484611396647 | 4.65384126965637 | 0.0336763181390697 |
Orange juice | Congenital malformations of eye, ear, face and neck (finn-b-Q17_CONGEN_MALFO_EYE_EAR_FACE_NECK) | All - Inverse variance weighted | -1.26815518659745 | 0.63051380811015 | 0.0442933156988488 |
Orange juice | Other congenital malformations of face and neck (finn-b-Q17_OTHER_CONGEN_MALFO_FACE_NECK) | rs10084140 | 6.45140869184884 | 2.86601385240029 | 0.0243852830149439 |
Orange juice | Other congenital malformations of face and neck (finn-b-Q17_OTHER_CONGEN_MALFO_FACE_NECK) | rs76481326 | 7.79895819300373 | 3.79114464053168 | 0.0396716726761551 |
Orange juice | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | rs12534433 | -17.8609144733704 | 5.70949697832708 | 0.0017583161732213 |
Orange juice | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | All - Inverse variance weighted | -4.52609769133059 | 2.1779774932405 | 0.0376983459252015 |
Orange juice | Injury of nerves at shoulder and upper arm level (finn-b-ST19_INJURY_NERVES_SHOUL_UPPER_ARM_LEVEL) | All - Inverse variance weighted | 4.89540120946514 | 1.72731489001479 | 0.0045953443818425 |
Orange juice | Rheumatoid arthritis (ieu-a-832) | All - Inverse variance weighted | -0.680931850046817 | 0.322569855231126 | 0.0347758065127483 |
Orange juice | Rheumatoid arthritis (ieu-a-833) | All - Inverse variance weighted | -0.62546559445345 | 0.261700206854539 | 0.0168480046705022 |
Orange juice | Osteomyelitis (ieu-b-4975) | rs6576250 | 1.7008206553953 | 0.829871009624884 | 0.0404132453505947 |
Orange juice | Osteomyelitis (ieu-b-4975) | All - MR Egger | -1.40063723490449 | 0.624754998480372 | 0.0488466566805745 |
Orange juice | Bone morphogenetic protein 10 (prot-a-254) | rs76481326 | -2.52817818492074 | 1.11814630203422 | 0.0237565216126146 |
Orange juice | Bone morphogenetic protein 10 (prot-a-254) | All - MR Egger | -1.97104829902634 | 0.823702011414228 | 0.0436568222905535 |
Orange juice | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | rs10084140 | 0.552850043594488 | 0.172062983244178 | 0.0013132525121956 |
Orange juice | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | All - Inverse variance weighted | 0.133599710652377 | 0.0630724794329098 | 0.0341586905843037 |
Orange juice | Pain type(s) experienced in last month: Knee pain (ukb-a-476) | All - Inverse variance weighted | 0.0250115735345471 | 0.0126846727266985 | 0.048633019893175 |
Orange juice | Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC (ukb-b-14157) | All - Inverse variance weighted | -0.0075810627865609 | 0.0034349638599751 | 0.0273120753981664 |
Orange juice | Diagnoses - main ICD10: M75.4 Impingement syndrome of shoulder (ukb-b-1418) | All - Inverse variance weighted | 0.0061273632726942 | 0.0030901204691367 | 0.0473799241565149 |
Orange juice | Fracture resulting from simple fall (ukb-b-15251) | All - Inverse variance weighted | -0.0767238981638216 | 0.0390386507477396 | 0.0493758579393974 |
Orange juice | Fractured bone site(s): Arm (ukb-b-19255) | All - Inverse variance weighted | -0.0097389030018595 | 0.0039534720821012 | 0.0137634061310719 |
Orange juice | Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) | rs10084140 | 0.417914313091871 | 0.143845407903407 | 0.0036689921387117 |
Orange juice | Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) | rs117044389 | 0.326972685587122 | 0.155553266557474 | 0.0355534338873427 |
Orange juice | Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) | All - Inverse variance weighted | 0.094446358828819 | 0.0455840668276056 | 0.0382732726523556 |
Orange juice | Fractured bone site(s): Leg (ukb-b-3798) | All - Inverse variance weighted | -0.006822211949706 | 0.0031537828504587 | 0.0305270462677851 |
Orange juice | Heel bone mineral density (BMD) (right) (ukb-b-4657) | rs10084140 | 0.4143634485398 | 0.143851450703698 | 0.0039705068915632 |
Orange juice | Heel bone mineral density (BMD) (right) (ukb-b-4657) | rs117044389 | 0.344093007777437 | 0.155598543442605 | 0.0270070876774848 |
Orange juice | Heel bone mineral density (BMD) (right) (ukb-b-4657) | All - Inverse variance weighted | 0.0929276795189382 | 0.0460890839595551 | 0.0437725614994078 |
Orange juice | Operative procedures - secondary OPCS: Z81.5 Elbow joint (ukb-b-7443) | All - Inverse variance weighted | 0.0061928858743543 | 0.0026516091198968 | 0.0195162774076157 |
Orange juice | Heel bone mineral density (BMD) (ukb-e-3148_EAS) | rs76481326 | 1.49535228344335 | 0.719497956800934 | 0.0376792188485117 |
Orange juice | Heel bone mineral density (BMD) (ukb-e-3148_EAS) | All - Inverse variance weighted | 1.10636006565694 | 0.516301185621827 | 0.0321245117508346 |
Orange juice | Pain in joint (ukb-e-745_AFR) | rs79774500 | -3.42592457113235 | 1.67533773261902 | 0.0408631616304291 |
Orange juice | Pain in joint (ukb-e-745_AFR) | All - Inverse variance weighted | -2.04757132811493 | 0.953500074630871 | 0.0317593428148463 |
Orange juice | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_EAS) | rs76481326 | 1.61210651578427 | 0.730724325295253 | 0.0273716745381046 |
Orange juice | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_EAS) | All - Inverse variance weighted | 1.23992736879963 | 0.524289479052423 | 0.0180316727017552 |