ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Cabbage/kale | Total body bone mineral density (ebi-a-GCST005348) | rs4676603 | 0.572151321539272 | 0.237763072897724 | 0.0161109362738446 |
| Cabbage/kale | Total body bone mineral density (ebi-a-GCST005348) | rs617579 | 0.567489526480063 | 0.270392068499324 | 0.0358375834709741 |
| Cabbage/kale | Heel bone mineral density (ebi-a-GCST006979) | rs150358228 | -0.232345211294146 | 0.0915280023008797 | 0.0111324014810537 |
| Cabbage/kale | Heel bone mineral density (ebi-a-GCST006979) | rs282406 | 0.16597574201269 | 0.0832041485396592 | 0.046064557712066 |
| Cabbage/kale | Heel bone mineral density (ebi-a-GCST006979) | rs617579 | 0.236953248877539 | 0.0891963346852937 | 0.0078948087551231 |
| Cabbage/kale | Heel bone mineral density (ebi-a-GCST006979) | All - MR Egger | -0.118279714397726 | 0.0531147583753872 | 0.041697436511748 |
| Cabbage/kale | Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) | rs117630679 | -1.97951174125221 | 0.775360802961566 | 0.0106793322620394 |
| Cabbage/kale | Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) | All - Inverse variance weighted | -0.294998126152765 | 0.124376007976613 | 0.0177004716764257 |
| Cabbage/kale | Spine arthritis or spondylitis (ebi-a-GCST90038657) | rs150358228 | 0.0196759925023058 | 0.0093345399728258 | 0.0350422754139653 |
| Cabbage/kale | Spine arthritis or spondylitis (ebi-a-GCST90038657) | All - Inverse variance weighted | 0.005424088675289 | 0.0021934652184453 | 0.0134044115655568 |
| Cabbage/kale | Cervical spondylosis (ebi-a-GCST90038693) | rs4676603 | -0.0148827741196524 | 0.0075676511939723 | 0.0492258174446235 |
| Cabbage/kale | Cervical spondylosis (ebi-a-GCST90038693) | rs758166 | -0.0141657550670598 | 0.0069856762467498 | 0.0425777299475735 |
| Cabbage/kale | Cervical spondylosis (ebi-a-GCST90038693) | All - MR Egger | -0.0103875788504476 | 0.0045004462538384 | 0.0356598215699122 |
| Cabbage/kale | Arthritis (not osteoarthritis) (ebi-a-GCST90038699) | rs758166 | 0.0186142866560813 | 0.0073274841973882 | 0.0110745380662452 |
| Cabbage/kale | Arthritis (not osteoarthritis) (ebi-a-GCST90038699) | All - MR Egger | 0.0091920477801974 | 0.0042802750015296 | 0.0485007158457678 |
| Cabbage/kale | Neck injury (ebi-a-GCST90038700) | rs2314759 | 0.0179195057297455 | 0.0084779965020313 | 0.0345452886772573 |
| Cabbage/kale | Neck injury (ebi-a-GCST90038700) | rs758166 | -0.0170756480551362 | 0.0074030640920635 | 0.0210790861688936 |
| Cabbage/kale | Neck injury (ebi-a-GCST90038700) | All - MR Egger | -0.0120459383435904 | 0.0048235829933343 | 0.024636685818952 |
| Cabbage/kale | Fracture of forearm or wrist (ebi-a-GCST90038705) | rs72652073 | 0.0221610726073395 | 0.0070551063006605 | 0.0016829188993112 |
| Cabbage/kale | Fracture of forearm or wrist (ebi-a-GCST90038705) | All - MR Egger | -0.0086155084575067 | 0.0034916397843369 | 0.0261284399151354 |
| Cabbage/kale | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs118053517 | 12.1530941115389 | 5.12730086891782 | 0.0177750367564968 |
| Cabbage/kale | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs138929729 | 12.5502207008378 | 5.88685703990631 | 0.0330146467231544 |
| Cabbage/kale | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs617579 | 10.4284545924924 | 4.99390783302455 | 0.0367766150409725 |
| Cabbage/kale | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | All - Inverse variance weighted | 3.13345322624034 | 1.05424556438351 | 0.0029565157318822 |
| Cabbage/kale | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs118053517 | 12.1961971375672 | 5.12730086891782 | 0.0173748518822025 |
| Cabbage/kale | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs138929729 | 12.4961715160796 | 5.87334474371678 | 0.0333696513314726 |
| Cabbage/kale | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs617579 | 10.3783819872148 | 4.99724600670973 | 0.037818147212221 |
| Cabbage/kale | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | All - Inverse variance weighted | 3.10782558377564 | 1.05512792110719 | 0.0032248620471406 |
| Cabbage/kale | Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) | rs150358228 | -1.94583015144152 | 0.930269460780911 | 0.036466753780871 |
| Cabbage/kale | Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) | All - Inverse variance weighted | -1.30979696677786 | 0.384883919288606 | 0.0006662684023856 |
| Cabbage/kale | Ankylosing spondylitis, strict definition (finn-b-M13_ANKYLOSPON_STRICT) | rs117630679 | -6.09568888986026 | 2.29590057897076 | 0.0079300948544324 |
| Cabbage/kale | Ankylosing spondylitis, strict definition (finn-b-M13_ANKYLOSPON_STRICT) | All - Inverse variance weighted | -1.43766104050487 | 0.592096810626627 | 0.0151788097065628 |
| Cabbage/kale | Monoarthritis, not elsewhere classified (finn-b-M13_MONOARTHRITIS) | rs117630679 | -4.60116793274239 | 2.25531122150029 | 0.0413356200303161 |
| Cabbage/kale | Monoarthritis, not elsewhere classified (finn-b-M13_MONOARTHRITIS) | All - MR Egger | -3.1168504689712 | 1.16351487516922 | 0.0153249515472455 |
| Cabbage/kale | Shoulder lesions (finn-b-M13_SHOULDER) | All - MR Egger | -0.529667781707346 | 0.245886655445983 | 0.0450292488098517 |
| Cabbage/kale | Transient synovitis (finn-b-M13_TRANSSYNOVITIS) | rs617579 | 14.4142339725936 | 6.65631832824262 | 0.0303496839489928 |
| Cabbage/kale | Transient synovitis (finn-b-M13_TRANSSYNOVITIS) | All - Inverse variance weighted | 3.29389728418688 | 1.40315799619799 | 0.0189004557158076 |
| Cabbage/kale | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | rs150358228 | 1.9021927780147 | 0.908450774067499 | 0.0362700954510732 |
| Cabbage/kale | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | rs4676603 | 6.0341879413952 | 2.08992655400967 | 0.0038859723385063 |
| Cabbage/kale | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | All - MR Egger | 2.03348260068698 | 0.788807001537993 | 0.0189582367226278 |
| Cabbage/kale | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | rs617579 | 17.8558910420109 | 6.97678300201959 | 0.0104874091968927 |
| Cabbage/kale | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | All - MR Egger | -6.86525095842306 | 2.91095966472447 | 0.0298634901344933 |
| Cabbage/kale | Seropositive rheumatoid arthritis, strict definition (finn-b-RHEUMA_SEROPOS_STRICT) | rs116816200 | 5.04518244557136 | 2.28466847142258 | 0.0272249206097905 |
| Cabbage/kale | Seropositive rheumatoid arthritis, strict definition (finn-b-RHEUMA_SEROPOS_STRICT) | All - Inverse variance weighted | -0.920948355241006 | 0.415390635968957 | 0.0266185982909208 |
| Cabbage/kale | Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) | rs72652073 | -2.93276142893308 | 1.33263915093213 | 0.0277560754833219 |
| Cabbage/kale | Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) | rs758166 | -1.54646029317937 | 0.75646937751621 | 0.0409226213454646 |
| Cabbage/kale | Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) | All - Inverse variance weighted | -0.704452637161321 | 0.283079462384839 | 0.0128271264300904 |
| Cabbage/kale | Fracture of lower leg, including ankle (finn-b-ST19_FRACT_LOWER_LEG_INCLU_ANKLE) | All - Inverse variance weighted | 0.298458150322614 | 0.150922769603085 | 0.0479788756829293 |
| Cabbage/kale | Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) | rs118191814 | -6.81362398265029 | 2.83266076914495 | 0.0161556814854182 |
| Cabbage/kale | Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) | rs2314759 | -4.51820947730875 | 2.14068392574104 | 0.0348034132035684 |
| Cabbage/kale | Open wound of ankle and foot (finn-b-ST19_OPEN_WOUND_ANKLE_FOOT) | All - Inverse variance weighted | -1.26711433477962 | 0.410620255602376 | 0.0020296816362191 |
| Cabbage/kale | Rheumatoid arthritis (ieu-a-832) | rs617579 | 1.62870161734515 | 0.823670989601589 | 0.0479999167192015 |
| Cabbage/kale | Rheumatoid arthritis (ieu-a-832) | All - Inverse variance weighted | 0.84908187342421 | 0.430349603949281 | 0.0484950051026109 |
| Cabbage/kale | Bone morphogenetic protein receptor type-1A (prot-a-259) | rs117299129 | -2.66107773054362 | 1.22426199919253 | 0.0297338469884276 |
| Cabbage/kale | Bone morphogenetic protein receptor type-1A (prot-a-259) | rs4676603 | -2.58499487018028 | 1.15950210892589 | 0.0257872524442921 |
| Cabbage/kale | Fractured bone site(s): Wrist (ukb-a-439) | rs10962528 | 0.0342666607256903 | 0.0162291880170506 | 0.0347360763615174 |
| Cabbage/kale | Fractured bone site(s): Wrist (ukb-a-439) | rs138929729 | -0.0394243761823259 | 0.016983244752725 | 0.0202669425631625 |
| Cabbage/kale | Fractured bone site(s): Wrist (ukb-a-439) | rs2314759 | 0.034684317440653 | 0.0158889987064804 | 0.0290421451512578 |
| Cabbage/kale | Fractured bone site(s): Wrist (ukb-a-439) | All - MR Egger | -0.0165615105995857 | 0.0077198776089755 | 0.0458197130911906 |
| Cabbage/kale | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) | rs117630679 | 0.116490415187497 | 0.0487206546751134 | 0.0168031823747818 |
| Cabbage/kale | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) | rs148641529 | 0.106662711696823 | 0.0488647117815727 | 0.0290493071561598 |
| Cabbage/kale | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) | All - MR Egger | 0.0685583918050615 | 0.021656653004746 | 0.0053508576190979 |
| Cabbage/kale | Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) | All - Inverse variance weighted | -0.0086704862575661 | 0.0036444030214631 | 0.0173538428233198 |
| Cabbage/kale | Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) | All - MR Egger | -0.0184573682897624 | 0.0071375971272946 | 0.0186421034933275 |
| Cabbage/kale | Diagnoses - main ICD10: S66 Injury of muscle and tendon at wrist and hand level (ukb-a-591) | rs118191814 | -0.0107380292191271 | 0.0049276732725803 | 0.0293221846081907 |
| Cabbage/kale | Diagnoses - main ICD10: S66 Injury of muscle and tendon at wrist and hand level (ukb-a-591) | rs138929729 | 0.0102492568237096 | 0.0049192505179713 | 0.0372057018781401 |
| Cabbage/kale | Diagnoses - main ICD10: S66 Injury of muscle and tendon at wrist and hand level (ukb-a-591) | All - Inverse variance weighted | -0.0032288096196927 | 0.0010748531963851 | 0.0026649556440789 |
| Cabbage/kale | Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) | rs72652073 | 0.0142258990537784 | 0.0056870734002359 | 0.0123687791988029 |
| Cabbage/kale | Non-cancer illness code, self-reported: ankylosing spondylitis (ukb-b-18194) | rs72652073 | 0.014598082719157 | 0.0055068566433733 | 0.0080279485932136 |
| Cabbage/kale | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | rs148641529 | 0.113761882565645 | 0.0410549175812534 | 0.0055889836765852 |
| Cabbage/kale | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | All - MR Egger | 0.0451406792218344 | 0.0199008927668297 | 0.035852795295754 |
| Cabbage/kale | Operative procedures - secondary OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-20239) | All - Inverse variance weighted | -0.0107035112001159 | 0.0047345316306621 | 0.0237758048089065 |
| Cabbage/kale | Non-cancer illness code, self-reported: cervical spondylosis (ukb-b-2349) | All - Inverse variance weighted | 0.0097361304758662 | 0.0049215417212787 | 0.047898435763399 |
| Cabbage/kale | Operative procedures - secondary OPCS: Z81.5 Elbow joint (ukb-b-7443) | rs72652073 | 0.0118780659059319 | 0.0053980005636251 | 0.027774516697679 |
| Cabbage/kale | Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure (ukb-b-8566) | rs10962528 | -0.0135142731957997 | 0.0064029615767351 | 0.0348042559131141 |
| Cabbage/kale | Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure (ukb-b-8566) | All - Inverse variance weighted | -0.0091446038033045 | 0.0046465978588922 | 0.0490655809347748 |
| Cabbage/kale | Heel bone mineral density (BMD) (left) (ukb-e-4105_AFR) | rs10962528 | -3.3236049844792 | 1.61780213578102 | 0.0399374547461703 |
| Cabbage/kale | Heel bone mineral density (BMD) (left) (ukb-e-4105_AFR) | All - Inverse variance weighted | -0.688169702030415 | 0.326775309494305 | 0.0352094298066192 |
| Cabbage/kale | Ankle spacing width (right) (ukb-e-4119_AFR) | All - Inverse variance weighted | 0.503402881844473 | 0.242587280567666 | 0.0379734421376075 |