ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
Intake (exposure) | Outcome | SNP | b | se | P-value |
---|---|---|---|---|---|
White wine | Frozen shoulder (ebi-a-GCST90000512) | rs10766353 | 0.959487996289988 | 0.412454487485611 | 0.0200031825226841 |
White wine | Frozen shoulder (ebi-a-GCST90000512) | rs2988328 | -1.19622991631223 | 0.464871344975518 | 0.0100748574317926 |
White wine | Frozen shoulder (ebi-a-GCST90000512) | rs4920553 | 1.07805439158656 | 0.47430367266453 | 0.0230309901551143 |
White wine | Shoulder impingement (ebi-a-GCST90014054) | All - Inverse variance weighted | -0.465749206414526 | 0.227316073028814 | 0.0404713331327138 |
White wine | Neck circumference (BMI adjusted) (ebi-a-GCST90017136) | rs4551638 | -1.71351084812623 | 0.825936883629191 | 0.0380211302072903 |
White wine | Neck circumference (BMI adjusted) (ebi-a-GCST90017136) | rs59696398 | 2.81407499884404 | 1.2660100799926 | 0.0262299395652749 |
White wine | Neck circumference (BMI adjusted) (ebi-a-GCST90017136) | All - MR Egger | 1.32009084749286 | 0.577157491721621 | 0.039585339679941 |
White wine | Joint disorder (ebi-a-GCST90038654) | rs1229984 | -0.0757967205085316 | 0.0238981082234562 | 0.0015156933033287 |
White wine | Joint disorder (ebi-a-GCST90038654) | All - Inverse variance weighted | -0.0136722680674506 | 0.0059122672429038 | 0.0207487481976449 |
White wine | Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) | rs1229984 | -2.749751238458 | 1.39686887383837 | 0.0490093132884874 |
White wine | Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) | All - Inverse variance weighted | -0.447561867038355 | 0.181860339807763 | 0.0138542783849149 |
White wine | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | rs72805122 | -1.45307553031774 | 0.411247791599359 | 0.0004103547314102 |
White wine | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | rs7644783 | -0.940693547697439 | 0.427587976226109 | 0.0278068950269972 |
White wine | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | All - Inverse variance weighted | -0.365489766733061 | 0.148127671404981 | 0.0136099383888146 |
White wine | Loose body in joint (finn-b-M13_LOOSEJOINT) | rs72805122 | -6.26083637930864 | 2.59579606057515 | 0.0158690322078888 |
White wine | Loose body in joint (finn-b-M13_LOOSEJOINT) | All - Inverse variance weighted | -1.66627619308027 | 0.795074527658671 | 0.0361045132305103 |
White wine | Peroneal tendinitis (finn-b-M13_PERONEALTEND) | rs73137883 | 13.350391294158 | 5.84223077536405 | 0.0223038568819154 |
White wine | Peroneal tendinitis (finn-b-M13_PERONEALTEND) | All - Inverse variance weighted | 2.85074027103037 | 1.24066243619023 | 0.0215756475362324 |
White wine | Collapsed vertebra, not elsewhere classified (finn-b-M13_VERTEBCOLLAPSE) | rs73137883 | 18.8676510028196 | 7.63621603206703 | 0.0134806825646896 |
White wine | Collapsed vertebra, not elsewhere classified (finn-b-M13_VERTEBCOLLAPSE) | All - MR Egger | 9.55728542858219 | 4.13184032308367 | 0.0410752189705644 |
White wine | Villonodular synovitis (pigmented) (finn-b-M13_VILLONODULAR) | rs339866 | 10.5108395017036 | 4.20751128089345 | 0.0124856313891569 |
White wine | Villonodular synovitis (pigmented) (finn-b-M13_VILLONODULAR) | rs4551638 | 10.6971153846154 | 4.43786982248521 | 0.0159343110272432 |
White wine | Villonodular synovitis (pigmented) (finn-b-M13_VILLONODULAR) | All - MR Egger | -8.15447514126223 | 3.56625176000659 | 0.043036587993802 |
White wine | Contusion of ankle (finn-b-ST19_CONTU_ANKLE) | All - Inverse variance weighted | -1.38065213764412 | 0.699477088599897 | 0.0484005436976214 |
White wine | Crushing injury of wrist and hand (finn-b-ST19_CRUSHI_INJURY_WRIST_HAND) | All - MR Egger | 6.40204823139392 | 2.7722345031505 | 0.0413462871219796 |
White wine | Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) | rs116453290 | 1.41383696717792 | 0.673834428483076 | 0.0358878001461724 |
White wine | Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) | rs339866 | 1.50517762048566 | 0.701781126850908 | 0.0319691307708373 |
White wine | Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) | All - Inverse variance weighted | 0.509215746661884 | 0.231785587490809 | 0.0280257429981427 |
White wine | Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) | rs59696398 | 6.11642853840107 | 2.42659638414944 | 0.0117161845992634 |
White wine | Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) | All - MR Egger | 4.87164374296613 | 2.18288030443848 | 0.0473809398807812 |
White wine | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | rs116453290 | 9.97788094601492 | 4.67362917230446 | 0.0327665567851102 |
White wine | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | All - Inverse variance weighted | 4.24334987353135 | 1.62143143370096 | 0.0088696114396579 |
White wine | Femoral neck bone mineral density (ieu-a-980) | rs73234113 | -0.694536978247067 | 0.284736416376019 | 0.0147186872235382 |
White wine | Femoral neck bone mineral density (ieu-a-980) | rs7644783 | -0.690028319480579 | 0.259216987741382 | 0.007768437931186 |
White wine | Femoral neck bone mineral density (ieu-a-980) | All - Inverse variance weighted | -0.178066594103379 | 0.0755267938457185 | 0.0183904669697538 |
White wine | Lumbar spine bone mineral density (ieu-a-982) | rs72805122 | -0.666583320447569 | 0.302195843874985 | 0.0273980693503048 |
White wine | Lumbar spine bone mineral density (ieu-a-982) | rs72863217 | -0.660891796375667 | 0.318339724791338 | 0.0378885684355617 |
White wine | Lumbar spine bone mineral density (ieu-a-982) | rs73234113 | -0.705678724570116 | 0.341662825185043 | 0.0388828649413075 |
White wine | Lumbar spine bone mineral density (ieu-a-982) | All - Inverse variance weighted | -0.241090394330298 | 0.0994611623345643 | 0.0153520773582785 |
White wine | Fracture resulting from simple fall (ukb-b-15251) | rs1229984 | 0.256692190730259 | 0.117452658033423 | 0.0288525759869625 |
White wine | Fracture resulting from simple fall (ukb-b-15251) | All - MR Egger | 0.161275383007889 | 0.0736122172589629 | 0.0489308061440333 |
White wine | Non-cancer illness code, self-reported: arthritis (nos) (ukb-b-8229) | All - Inverse variance weighted | -0.0047975527580027 | 0.0022949167070973 | 0.0365717595218404 |
White wine | Diagnoses - main ICD10: S02 Fracture of skull and facial bones (ukb-d-S02) | rs339866 | 0.0107029560545293 | 0.0046760851409754 | 0.0220868439299962 |
White wine | Diagnoses - main ICD10: S02 Fracture of skull and facial bones (ukb-d-S02) | All - Inverse variance weighted | 0.0027340658137559 | 0.0013353593817907 | 0.0406150785621086 |
White wine | Ankle spacing width (left) (ukb-e-4100_CSA) | All - Inverse variance weighted | 0.502738868071009 | 0.164046270002169 | 0.0021794943885671 |
White wine | Ankle spacing width (left) (ukb-e-4100_EAS) | rs1229984 | -1.48840836599629 | 0.471131178469911 | 0.0015819050010933 |
White wine | Ankle spacing width (left) (ukb-e-4100_EAS) | All - Inverse variance weighted | -0.558790179711495 | 0.276522855393821 | 0.043303171775545 |