ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Pizza | Rheumatoid Arthritis (bbj-a-72) | rs56099106 | -1.06670805873362 | 0.477194480195405 | 0.0253928159073847 |
| Pizza | Rheumatoid Arthritis (bbj-a-72) | All - Inverse variance weighted | -0.781199119071734 | 0.371717621937508 | 0.0355889514013436 |
| Pizza | Rheumatoid Arthritis (bbj-a-73) | rs117917823 | 3.71023601847101 | 1.39779659084431 | 0.0079462262876058 |
| Pizza | Rheumatoid Arthritis (bbj-a-73) | rs142169213 | 2.72944226140268 | 1.38107679963791 | 0.0481191555202731 |
| Pizza | Rheumatoid Arthritis (bbj-a-73) | All - Inverse variance weighted | 0.755757924411436 | 0.367492665156932 | 0.0397319204316837 |
| Pizza | Total body bone mineral density (age 15-30) (ebi-a-GCST005344) | rs2990534 | 3.37839367796572 | 1.48993501347282 | 0.0233610899495301 |
| Pizza | Total body bone mineral density (age 15-30) (ebi-a-GCST005344) | All - Inverse variance weighted | 0.775568378942139 | 0.379908303986897 | 0.0412049238955806 |
| Pizza | Osteoarthritis (hip) (ebi-a-GCST007091) | rs79236871 | 1.55992007915893 | 0.740861785667382 | 0.0352436303628042 |
| Pizza | Osteoarthritis (hip) (ebi-a-GCST007091) | All - Inverse variance weighted | 0.383777346386708 | 0.174607384445943 | 0.0279530587318605 |
| Pizza | Osteoarthritis (hip) (ebi-a-GCST007091) | All - MR Egger | 0.8802434572761 | 0.337671508042929 | 0.019828535775816 |
| Pizza | Osteoarthritis of the hip or knee (ebi-a-GCST007092) | All - MR Egger | 0.496677768113856 | 0.220573657213563 | 0.0397537690029378 |
| Pizza | Ulcerative colitis vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016625) | rs2990534 | -0.860448791975183 | 0.380408939610081 | 0.0237032881067702 |
| Pizza | Ulcerative colitis vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016625) | rs79236871 | 0.21052905952659 | 0.0892242204660311 | 0.0182970872732546 |
| Pizza | Ulcerative colitis vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016625) | All - MR Egger | 0.324261434632308 | 0.104976877178294 | 0.0149147394067872 |
| Pizza | Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) | rs17688422 | -16.2981035191989 | 6.73295602301687 | 0.0154929535673301 |
| Pizza | Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) | rs79236871 | 6.41311616091237 | 3.0366310538383 | 0.0346934724990576 |
| Pizza | Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) | All - MR Egger | 8.69548076146257 | 2.65093610549796 | 0.0054742274159814 |
| Pizza | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | All - Inverse variance weighted | -3.38325156460284 | 1.63971711652212 | 0.0390827884495471 |
| Pizza | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | rs2990534 | 13.0969363494328 | 5.21250820822861 | 0.011984590127777 |
| Pizza | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | All - MR Egger | -4.32913839266361 | 1.97629991857382 | 0.045907784676203 |
| Pizza | Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) | rs1036286 | -4.86114453482216 | 2.40951532945084 | 0.0436456387438782 |
| Pizza | Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) | rs17154988 | -5.55289644299997 | 2.62415359331644 | 0.0343387330512066 |
| Pizza | Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) | rs74453184 | -6.91785617091467 | 3.14731294262334 | 0.0279476948420807 |
| Pizza | Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) | rs9894036 | -3.98915737747692 | 1.78439416121878 | 0.0253792415622121 |
| Pizza | Calcific tendinitis of shoulder (finn-b-M13_CALCIFICTEND) | All - Inverse variance weighted | -2.98506753623603 | 0.708261879761805 | 2.50178979485948e-05 |
| Pizza | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | rs1480734 | 17.4723163408853 | 8.36394090503533 | 0.0367072518773715 |
| Pizza | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | All - MR Egger | -9.90437092044537 | 3.59904458440422 | 0.0155853614976213 |
| Pizza | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | All - Inverse variance weighted | 0.399577129174982 | 0.167261676457758 | 0.0168973311447214 |
| Pizza | Lower back pain or/and sciatica (finn-b-M13_LOWBACKPAINORANDSCIATICA) | rs9894036 | 1.09006044617102 | 0.405873570382826 | 0.0072374948691243 |
| Pizza | Lower back pain or/and sciatica (finn-b-M13_LOWBACKPAINORANDSCIATICA) | All - Inverse variance weighted | 0.400675282007251 | 0.159894534980231 | 0.0122149735771743 |
| Pizza | Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) | rs9894036 | 4.52983895516547 | 1.82933016365402 | 0.0132778677200098 |
| Pizza | Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) | All - MR Egger | 3.64384303676638 | 1.43279371751007 | 0.0234254021597947 |
| Pizza | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | rs117441119 | -7.46160051227037 | 3.25782334988233 | 0.0220002389499689 |
| Pizza | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | rs1480734 | -8.92774058646114 | 3.85901723694366 | 0.0206965279863262 |
| Pizza | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | All - Inverse variance weighted | -1.90675637855665 | 0.83057810042731 | 0.0216931621537164 |
| Pizza | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | rs9894036 | -1.07991360691145 | 0.54068157768855 | 0.0457905368643547 |
| Pizza | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | All - Inverse variance weighted | -0.569668511842068 | 0.210982143852101 | 0.0069322957578061 |
| Pizza | Osteonecrosis due to drugs (finn-b-OSTEON_DRUGS) | All - Inverse variance weighted | -5.63445384594646 | 2.0194438134886 | 0.0052691469089202 |
| Pizza | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | rs74453184 | 21.117119512717 | 8.96828381076236 | 0.018540437144629 |
| Pizza | Other osteochondrodysplasias (finn-b-Q17_OTHER_OSTEOCHONDROD) | All - Inverse variance weighted | 4.03172996054849 | 2.02089540978804 | 0.0460405258917861 |
| Pizza | Fracture at wrist and hand level (finn-b-ST19_FRACT_WRIST_HAND_LEVEL) | rs117222790 | 1.93375282288829 | 0.929492789209048 | 0.0374853075058427 |
| Pizza | Fracture at wrist and hand level (finn-b-ST19_FRACT_WRIST_HAND_LEVEL) | rs79236871 | 1.33836330699047 | 0.681713145133721 | 0.0496188400852345 |
| Pizza | Fracture at wrist and hand level (finn-b-ST19_FRACT_WRIST_HAND_LEVEL) | All - Inverse variance weighted | 0.780203685240908 | 0.27753793864651 | 0.004936315784832 |
| Pizza | Injuries to the wrist and hand (finn-b-ST19_INJURI_WRIST_HAND) | rs57529409 | 1.64853809138298 | 0.732089849333772 | 0.0243333447100759 |
| Pizza | Injuries to the wrist and hand (finn-b-ST19_INJURI_WRIST_HAND) | All - Inverse variance weighted | 0.332316514116761 | 0.164174978054076 | 0.042953635033562 |
| Pizza | Osteocalcin (prot-a-246) | All - Inverse variance weighted | -1.1693506944301 | 0.375551725975594 | 0.0018476510420594 |
| Pizza | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | rs142169213 | -0.0068971753039685 | 0.0029993005122719 | 0.0214711975186461 |
| Pizza | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | rs57529409 | -0.0098354668141533 | 0.0033221382367322 | 0.0030705712426075 |
| Pizza | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | All - Inverse variance weighted | -0.0025757269903798 | 0.0007662722434773 | 0.0007755595454405 |
| Pizza | Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) | All - Inverse variance weighted | 0.0159904377439032 | 0.0067472729684893 | 0.0177923582197124 |
| Pizza | Fractured heel (right) (ukb-b-3499) | All - Inverse variance weighted | -0.011974819473486 | 0.0060638504194827 | 0.0482922033286828 |
| Pizza | Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) | rs1480734 | -0.017706101626261 | 0.0087942897492459 | 0.0440764068685972 |
| Pizza | Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) | rs17688422 | -0.0186555837671456 | 0.0082551998373499 | 0.0238300324318496 |
| Pizza | Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) | All - Inverse variance weighted | -0.0182108345046227 | 0.006018870350889 | 0.0024812119800142 |
| Pizza | Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) | rs1480734 | 0.0198788651752432 | 0.008104812002912 | 0.0141779159876338 |
| Pizza | Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) | All - Inverse variance weighted | 0.0042305692392852 | 0.0021560486368114 | 0.0497407906908416 |
| Pizza | Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) | rs111868420 | 0.0439676297793463 | 0.0178905423661364 | 0.0139872502380958 |
| Pizza | Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) | All - MR Egger | 0.0206587497060008 | 0.0087825540309419 | 0.0327347602961383 |
| Pizza | Diagnoses - main ICD10: M25 Other joint disorders, not elsewhere classified (ukb-d-M25) | rs111868420 | -0.0409746148771063 | 0.0202755029375111 | 0.0432908788529288 |
| Pizza | Diagnoses - main ICD10: S42 Fracture of shoulder and upper arm (ukb-d-S42) | rs111868420 | -0.0246572903685241 | 0.0100273460817476 | 0.0139322823832082 |
| Pizza | Diagnoses - main ICD10: S42 Fracture of shoulder and upper arm (ukb-d-S42) | All - MR Egger | -0.0123391923773459 | 0.0056174910009782 | 0.0467916035755108 |
| Pizza | Ankle spacing width (ukb-e-3143_CSA) | rs1480734 | -3.51143199645299 | 1.40293066358675 | 0.0123171204510485 |
| Pizza | Ankle spacing width (ukb-e-3143_CSA) | All - Inverse variance weighted | -0.801055128042539 | 0.408299561640965 | 0.0497706433394347 |
| Pizza | Internal derangement of knee (ukb-e-835_CSA) | rs56099106 | -6.0007717895817 | 2.59993920540166 | 0.0209967384270195 |
| Pizza | Internal derangement of knee (ukb-e-835_CSA) | All - Inverse variance weighted | -2.82854660836172 | 1.1756266609583 | 0.0161286829768796 |