ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Baked bean | Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) | rs9824684 | -0.988598044107692 | 0.44654985554874 | 0.0268385373198942 |
| Baked bean | Frozen shoulder (ebi-a-GCST90000512) | rs114412661 | 1.34397732424418 | 0.674408255106412 | 0.0462806630313764 |
| Baked bean | Frozen shoulder (ebi-a-GCST90000512) | All - Inverse variance weighted | 0.618238525955287 | 0.248528645018721 | 0.0128610228494815 |
| Baked bean | Heel bone mineral density T score (ebi-a-GCST90025982) | rs4894011 | -0.315829254983544 | 0.0998124243302696 | 0.0015549499894286 |
| Baked bean | Heel bone mineral density T score (ebi-a-GCST90025982) | All - Inverse variance weighted | -0.212707667604779 | 0.0908955814152215 | 0.0192769203266206 |
| Baked bean | Other joint disorder (ebi-a-GCST90038688) | All - Inverse variance weighted | -0.0066588325624762 | 0.0026777105793582 | 0.0128911114687716 |
| Baked bean | Other specified/unspecified disorders of bone/cartilage (finn-b-M13_BONEDISNAS) | All - Inverse variance weighted | 2.30260469799736 | 1.13152972183692 | 0.0418560562653913 |
| Baked bean | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | rs112608234 | -15.8009740400922 | 7.49916655795684 | 0.0351149199480322 |
| Baked bean | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | rs4894011 | -12.6954623740259 | 5.98536909776103 | 0.0339148501739319 |
| Baked bean | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | rs78813271 | -17.9708099499831 | 9.09030224718565 | 0.0480505539445398 |
| Baked bean | Contracture of joint (finn-b-M13_CONTRACTUREJOINT) | All - Inverse variance weighted | -4.06075571718748 | 2.04758163231423 | 0.0473455397535632 |
| Baked bean | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | rs73408360 | 5.57736470384332 | 2.83027860825859 | 0.0487689316331558 |
| Baked bean | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | All - Inverse variance weighted | 1.83641876337567 | 0.846780049167183 | 0.0301048509831791 |
| Baked bean | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | rs114412661 | 1.31637504003194 | 0.48662205271323 | 0.0068278032316776 |
| Baked bean | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | rs9956645 | 1.45992422134512 | 0.621755962502276 | 0.0188711619676748 |
| Baked bean | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | All - Inverse variance weighted | 0.485162012012544 | 0.19134243222409 | 0.0112264688142747 |
| Baked bean | Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) | All - Inverse variance weighted | 0.615928960626798 | 0.311379429338904 | 0.0479212983806174 |
| Baked bean | Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) | rs114412661 | -2.86774278073309 | 0.908777081349066 | 0.0016016483245253 |
| Baked bean | Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) | rs148676637 | -2.18486491467891 | 1.0789930422228 | 0.0428765005938361 |
| Baked bean | Dislocation, sprain and strain of joints and ligaments at wrist and hand level (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_WRIST_HAND_LEVEL) | All - Inverse variance weighted | -0.984667237777317 | 0.390329710176471 | 0.011647257132115 |
| Baked bean | Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) | All - Inverse variance weighted | -2.51876372957191 | 1.15798309810615 | 0.0296203789322191 |
| Baked bean | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | rs11610708 | -3.25276875676576 | 1.22304105254393 | 0.0078239431943216 |
| Baked bean | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | rs73408360 | -3.39009489145977 | 1.26695264092898 | 0.0074554100473065 |
| Baked bean | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | All - Inverse variance weighted | -0.889115707360228 | 0.43500996409405 | 0.0409636902451805 |
| Baked bean | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | rs114412661 | -10.6183427399733 | 5.24886350875296 | 0.0430752716510284 |
| Baked bean | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | All - Inverse variance weighted | -5.25140427095711 | 2.10073556193408 | 0.0124265855996879 |
| Baked bean | Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) | All - MR Egger | -10.7810685023894 | 4.56423312011624 | 0.0376754644983586 |
| Baked bean | Open wound of wrist and hand (finn-b-ST19_OPEN_WOUND_WRIST_HAND) | All - Inverse variance weighted | 0.612070529020552 | 0.286137766745963 | 0.032429485617548 |
| Baked bean | Superficial injury of shoulder and upper arm (finn-b-ST19_SUPERF_INJURY_SHOUL_UPPER_ARM) | rs12540361 | -4.64837692641234 | 1.73808876378896 | 0.0074858945750417 |
| Baked bean | Superficial injury of shoulder and upper arm (finn-b-ST19_SUPERF_INJURY_SHOUL_UPPER_ARM) | rs4609980 | 10.1389893606375 | 3.61555331261312 | 0.0050430581660405 |
| Baked bean | Bone sialoprotein 2 (prot-a-1395) | All - Inverse variance weighted | 0.658452216330442 | 0.261711458538728 | 0.0118712959372734 |
| Baked bean | Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) | rs11610708 | -0.0274097031393122 | 0.0124657028062287 | 0.0278914856439246 |
| Baked bean | Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) | rs12540361 | 0.027942257237137 | 0.0123709294549089 | 0.0239018568604107 |
| Baked bean | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | rs114412661 | 0.0064029480146236 | 0.002547112917112 | 0.011943607676209 |
| Baked bean | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | rs148676637 | 0.0083376595450566 | 0.002455473297802 | 0.0006849318725588 |
| Baked bean | Non-cancer illness code self-reported: joint disorder (ukb-a-86) | rs12540361 | -0.0222757938986838 | 0.008721273765516 | 0.01064350310795 |
| Baked bean | Non-cancer illness code self-reported: joint disorder (ukb-a-86) | All - MR Egger | 0.0122565592315273 | 0.0045189268989216 | 0.0188758605805351 |
| Baked bean | Diagnoses - secondary ICD10: M06.99 Rheumatoid arthritis, unspecified (Site unspecified) (ukb-b-11874) | rs11610708 | -0.0124286993088517 | 0.006202899908402 | 0.0451030916685041 |
| Baked bean | Operative procedures - secondary OPCS: S06.5 Excision of lesion of skin of head or neck NEC (ukb-b-12747) | rs11610708 | 0.0121739945041219 | 0.0056077733366641 | 0.0299376622731737 |
| Baked bean | Diagnoses - secondary ICD10: M13.99 Arthritis, unspecified (Site unspecified) (ukb-b-15026) | rs12540361 | -0.0179697800380689 | 0.0083004578559407 | 0.0303942476963217 |
| Baked bean | Operative procedures - secondary OPCS: Z84.3 Hip joint (ukb-b-17133) | rs12540361 | -0.0189157706751722 | 0.0080105681676208 | 0.0182084412669646 |
| Baked bean | Operative procedures - secondary OPCS: Z84.3 Hip joint (ukb-b-17133) | rs9956645 | -0.0226280697053701 | 0.0078634953677463 | 0.0040070069906688 |
| Baked bean | Non-cancer illness code, self-reported: ankylosing spondylitis (ukb-b-18194) | rs11610708 | 0.0129585623282538 | 0.0057239362145057 | 0.0235787276692528 |
| Baked bean | Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint (ukb-b-6725) | rs11610708 | -0.0140334332583895 | 0.0058319801815305 | 0.0161154839270823 |
| Baked bean | Fractured heel (left) (ukb-b-8221) | All - MR Egger | 0.0216889459838505 | 0.0095674685752 | 0.0410999249913698 |
| Baked bean | Operative procedures - main OPCS: W37.1 Primary total prosthetic replacement of hip joint using cement (ukb-b-898) | rs12540361 | -0.0203438696543665 | 0.0093700622478301 | 0.0299193596484116 |
| Baked bean | Operative procedures - main OPCS: W37.1 Primary total prosthetic replacement of hip joint using cement (ukb-b-898) | rs9956645 | -0.0205964048077881 | 0.0091981752664791 | 0.0251439611581745 |
| Baked bean | Operative procedures - main OPCS: W37.1 Primary total prosthetic replacement of hip joint using cement (ukb-b-898) | All - Inverse variance weighted | -0.0133488963958255 | 0.0046764203752614 | 0.0043103052125579 |
| Baked bean | Ankle spacing width (ukb-e-3143_CSA) | rs4609980 | -2.64482942994633 | 1.32098507744346 | 0.0452670421241535 |
| Baked bean | Ankle spacing width (ukb-e-3143_CSA) | All - MR Egger | -3.49345553487343 | 1.30871786313055 | 0.0320288116634599 |
| Baked bean | Ankle spacing width (ukb-e-3143_EAS) | All - MR Egger | -4.30525566832663 | 1.62975540015157 | 0.0458845625018085 |
| Baked bean | Ankle spacing width (left) (ukb-e-4100_AFR) | rs4609980 | -1.08552377630176 | 0.521817698340763 | 0.0375004106721145 |
| Baked bean | Ankle spacing width (left) (ukb-e-4100_AFR) | All - Inverse variance weighted | -0.751537152836939 | 0.369813500879509 | 0.0421328228577398 |
| Baked bean | Ankle spacing width (right) (ukb-e-4119_AFR) | rs4894011 | -2.22703476970823 | 1.080265334311 | 0.0392493838451102 |
| Baked bean | Ankle spacing width (right) (ukb-e-4119_AFR) | All - Inverse variance weighted | -0.799275220442453 | 0.333844340708374 | 0.0166586905047814 |