ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Danish pastry | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | rs114646421 | 8.21925130758013 | 4.1500729174662 | 0.0476465106379766 |
| Danish pastry | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | rs78824754 | 18.2771294015602 | 7.04016102217947 | 0.0094282095125711 |
| Danish pastry | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | All - Inverse variance weighted | 3.21645086282537 | 1.29804301165653 | 0.0132149595485246 |
| Danish pastry | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | All - MR Egger | 8.73306344223413 | 3.54538470786776 | 0.028495866565171 |
| Danish pastry | Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) | All - MR Egger | 8.64843227496101 | 3.46404527913747 | 0.0267583766797254 |
| Danish pastry | Bone mineral density (ebi-a-GCST90014022) | All - Inverse variance weighted | -0.150292571217381 | 0.0745714469787875 | 0.0438609616673625 |
| Danish pastry | Juvenile rheumatoid arthritis (ebi-a-GCST90018653) | All - Inverse variance weighted | -12.8436280173449 | 6.26639197604588 | 0.0404029969269322 |
| Danish pastry | Heel bone mineral density (ebi-a-GCST90029004) | rs4972364 | -0.5267306016844 | 0.221719645167252 | 0.0175175724329987 |
| Danish pastry | Heel bone mineral density (ebi-a-GCST90029004) | rs79846554 | -0.576701194493754 | 0.257180942720221 | 0.0249358711349011 |
| Danish pastry | Heel bone mineral density (ebi-a-GCST90029004) | All - Inverse variance weighted | -0.150167595390957 | 0.0650488347258462 | 0.0209693269875285 |
| Danish pastry | Fractures (ebi-a-GCST90038703) | rs77949626 | 0.0724359720508565 | 0.0330936948142433 | 0.0286102968720683 |
| Danish pastry | Fractures (ebi-a-GCST90038703) | All - MR Egger | 0.0731723966542856 | 0.0270222001238987 | 0.0179231987981652 |
| Danish pastry | Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) | rs71320525 | 12.3353675239006 | 5.49186548297432 | 0.0246965718512014 |
| Danish pastry | Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) | rs78824754 | 12.0989040928324 | 6.03833173015441 | 0.0451040026016199 |
| Danish pastry | Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) | All - Inverse variance weighted | 3.99499774133626 | 1.44743418680611 | 0.0057791658433571 |
| Danish pastry | Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) | rs71320525 | 12.1871814560853 | 5.49186548297432 | 0.0264776586021242 |
| Danish pastry | Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) | rs78824754 | 11.8653774513347 | 6.03833173015441 | 0.0494131718033257 |
| Danish pastry | Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) | All - Inverse variance weighted | 3.93990294455427 | 1.44932287907825 | 0.006558977665175 |
| Danish pastry | Benign neoplasm: Short bones of lower limb (finn-b-CD2_BENIGN_BONE_SHORT_LOWER) | All - Inverse variance weighted | 9.39151814622283 | 4.37895959365387 | 0.0319775076795427 |
| Danish pastry | Benign neoplasm: Short bones of lower limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_LOWER_EXALLC) | All - Inverse variance weighted | 9.38064043521625 | 4.37236116954259 | 0.0319176493432222 |
| Danish pastry | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | rs114646421 | 46.9056678253051 | 18.9201635982851 | 0.0131700900747962 |
| Danish pastry | Carcinoma in situ of skin of scalp and neck (finn-b-CD2_INSITU_SKIN_SCALPNECK) | All - Inverse variance weighted | 8.69093356776774 | 3.99937245718657 | 0.029774724413271 |
| Danish pastry | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | rs77949626 | 3.44874604657969 | 1.56307680028202 | 0.0273571958010525 |
| Danish pastry | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | All - Inverse variance weighted | 0.898136034821628 | 0.400879688371435 | 0.0250641280169765 |
| Danish pastry | Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) | rs76394359 | -21.1601077632514 | 9.19375898715766 | 0.0213592623301883 |
| Danish pastry | Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) | All - Inverse variance weighted | -7.72969049106955 | 3.48550823738942 | 0.0265776654123608 |
| Danish pastry | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | rs76394359 | -9.09045832438061 | 4.54936118870139 | 0.0456967730039073 |
| Danish pastry | Spinal osteochondrosis (finn-b-M13_SPINALOSTEOCHON) | rs114646421 | 32.73610456255 | 16.5215627364335 | 0.0475445336813363 |
| Danish pastry | Spinal osteochondrosis (finn-b-M13_SPINALOSTEOCHON) | rs150700637 | 46.0315036365253 | 20.6293889589122 | 0.0256575800415287 |
| Danish pastry | Spinal osteochondrosis (finn-b-M13_SPINALOSTEOCHON) | All - MR Egger | 23.5342018497172 | 9.70350142549726 | 0.0294053938514069 |
| Danish pastry | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | rs28361881 | 69.0125422654692 | 28.947083431936 | 0.017121269680342 |
| Danish pastry | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | All - MR Egger | 21.3312553968593 | 9.78567497535148 | 0.0468345114310685 |
| Danish pastry | Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) | rs12626168 | 10.5360071703382 | 4.32293349755196 | 0.0148000354137517 |
| Danish pastry | Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) | rs34599940 | 5.41508929222837 | 2.73997033049879 | 0.0481172599267946 |
| Danish pastry | Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) | All - MR Egger | -6.67527810154954 | 2.58439721168584 | 0.0216861712320811 |
| Danish pastry | Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) | rs73031773 | 6.66896765550687 | 3.21163442357305 | 0.0378474786900155 |
| Danish pastry | Injury of muscle and tendon at wrist and hand level (finn-b-ST19_INJURY_MUSCLE_TENDON_WRIST_HAND_LEVEL) | rs12626168 | -12.3346889499966 | 6.1216152772104 | 0.0439109111333941 |
| Danish pastry | Injury of muscle and tendon at wrist and hand level (finn-b-ST19_INJURY_MUSCLE_TENDON_WRIST_HAND_LEVEL) | rs76394359 | -7.30542287159315 | 2.81391005404691 | 0.009426609519187 |
| Danish pastry | Injury of muscle and tendon at wrist and hand level (finn-b-ST19_INJURY_MUSCLE_TENDON_WRIST_HAND_LEVEL) | All - Inverse variance weighted | -2.27741402870312 | 1.06999523028843 | 0.0333011320953754 |
| Danish pastry | Sequelae of injuries of neck and trunk (finn-b-ST19_SEQUEL_INJURI_NECK_TRUNK) | All - Inverse variance weighted | 5.43957512957123 | 2.60231829854753 | 0.0365926121320306 |
| Danish pastry | Bone sialoprotein 2 (prot-a-1395) | rs77949626 | 6.35540375604029 | 3.02970843629132 | 0.0359321109254218 |
| Danish pastry | Bone sialoprotein 2 (prot-a-1395) | All - Inverse variance weighted | 1.91454982705193 | 0.883620194627923 | 0.0302568773251282 |
| Danish pastry | Fractured bone site(s): Ankle (ukb-a-438) | rs150700637 | 0.0832888501924817 | 0.0388405057174701 | 0.0320023555062846 |
| Danish pastry | Fractured bone site(s): Ankle (ukb-a-438) | rs34599940 | -0.0840562909880917 | 0.039778856832497 | 0.0345930946777113 |
| Danish pastry | Fractured bone site(s): Ankle (ukb-a-438) | rs76879755 | 0.0779976560927777 | 0.0363720341089798 | 0.0319976233278443 |
| Danish pastry | Fractured bone site(s): Ankle (ukb-a-438) | All - MR Egger | 0.072350798446592 | 0.0280574436281242 | 0.0218659735575291 |
| Danish pastry | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) | rs76879755 | 0.299621975905896 | 0.12946891166153 | 0.0206546279526256 |
| Danish pastry | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-a-472) | rs79846554 | -0.295526988276145 | 0.140060082320582 | 0.0348582239122419 |
| Danish pastry | Operative procedures - secondary OPCS: Z81.4 Shoulder joint (ukb-b-11427) | rs34599940 | -0.0616653831499931 | 0.0251878663089033 | 0.0143564834893479 |
| Danish pastry | Operative procedures - secondary OPCS: Z81.4 Shoulder joint (ukb-b-11427) | All - Inverse variance weighted | -0.0299346729236207 | 0.0146396615100415 | 0.0408779951358884 |
| Danish pastry | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | rs4972364 | -0.261124165060591 | 0.104841328510706 | 0.0127505859686159 |
| Danish pastry | Pain type(s) experienced in last month: Neck or shoulder pain (ukb-b-18596) | All - Inverse variance weighted | -0.0726852489156544 | 0.0337609773916456 | 0.0313236498300482 |
| Danish pastry | Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) | All - Inverse variance weighted | -0.219163445688577 | 0.0862672387625924 | 0.0110688495707208 |
| Danish pastry | Operation code: shoulder surgery (ukb-b-5935) | All - Inverse variance weighted | -0.0277343555764259 | 0.0138517126466668 | 0.0452596826566639 |
| Danish pastry | Heel bone mineral density (BMD) (ukb-b-8875) | All - Inverse variance weighted | -0.209078924454504 | 0.0874519287826337 | 0.0168123085783669 |
| Danish pastry | Osteoarthrosis (ukb-e-740_CSA) | rs2862126 | 24.3314982304365 | 9.16240660637043 | 0.0079172293037137 |
| Danish pastry | Osteoarthrosis (ukb-e-740_CSA) | rs76394359 | 18.4536303984926 | 8.24752491611986 | 0.0252553147627107 |
| Danish pastry | Osteoarthrosis (ukb-e-740_CSA) | All - Inverse variance weighted | 6.41204765259077 | 3.06586349467777 | 0.03648927925093 |