ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
Intake (exposure) | Outcome | SNP | b | se | P-value |
---|---|---|---|---|---|
Turnip/swede | Heel bone mineral density (ebi-a-GCST006288) | rs142228490 | 0.871901737743586 | 0.418276191602451 | 0.037113620479863 |
Turnip/swede | Heel bone mineral density (ebi-a-GCST006288) | rs4240658 | 0.734554508054842 | 0.344587033354534 | 0.0330319157231814 |
Turnip/swede | Heel bone mineral density (ebi-a-GCST006288) | All - MR Egger | -0.294409013083958 | 0.131976388901946 | 0.0386577404001793 |
Turnip/swede | Juvenile rheumatoid arthritis (ebi-a-GCST90018653) | All - Inverse variance weighted | -4.96059057173044 | 2.39380055004574 | 0.0382406771303106 |
Turnip/swede | Spine arthritis or spondylitis (ebi-a-GCST90038657) | All - Inverse variance weighted | -0.0098345210614109 | 0.0044779522167377 | 0.0280769539172611 |
Turnip/swede | Cervical spondylosis (ebi-a-GCST90038693) | rs1276460 | -0.0383542134499468 | 0.0173448764921404 | 0.027017111954528 |
Turnip/swede | Cervical spondylosis (ebi-a-GCST90038693) | All - Inverse variance weighted | -0.0081633343278282 | 0.0040441679265206 | 0.0435345484301645 |
Turnip/swede | Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) | rs16826913 | 24.8354788809942 | 12.6569832988123 | 0.0497396981510233 |
Turnip/swede | Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) | All - Inverse variance weighted | 6.66185772800345 | 3.22412959272896 | 0.0388048811608334 |
Turnip/swede | Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) | rs16826913 | 25.061613486799 | 12.6864791169608 | 0.0482161354004117 |
Turnip/swede | Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) | All - Inverse variance weighted | 6.63446452133588 | 3.22326807642278 | 0.0395609918146653 |
Turnip/swede | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | rs142228490 | -10.7166714076139 | 5.19053813479418 | 0.0389556389298303 |
Turnip/swede | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | rs75193468 | -31.7778113691822 | 13.243582584982 | 0.0164180386670244 |
Turnip/swede | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | All - Inverse variance weighted | -3.57952413629975 | 1.75631624900925 | 0.0415413001236751 |
Turnip/swede | Chondromalacia (finn-b-M13_CHONDROMALACIA) | All - MR Egger | 5.28301229368982 | 2.47414527215006 | 0.0475856512146828 |
Turnip/swede | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | rs11073499 | 10.5054947806365 | 5.29969349410461 | 0.0474475236468978 |
Turnip/swede | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | rs77004945 | -8.23883229011165 | 4.02229613527835 | 0.0405315109591339 |
Turnip/swede | Osteomyelitis (finn-b-M13_OSTEOMYELITIS) | All - MR Egger | -4.38429565988781 | 1.75499850624882 | 0.023033612020374 |
Turnip/swede | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | rs142228490 | -7.85931851813972 | 3.94723805201405 | 0.0464706509854021 |
Turnip/swede | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | rs146863310 | -8.0086868866554 | 3.43176495004299 | 0.0196117869338221 |
Turnip/swede | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | All - Inverse variance weighted | -4.43030156584211 | 1.27009917142417 | 0.000486367771802 |
Turnip/swede | Osteonecrosis (finn-b-M13_OSTEONECROSIS) | All - MR Egger | -6.1272339958765 | 2.08812436536348 | 0.0092628673472604 |
Turnip/swede | Bursitis of shoulder (finn-b-M13_SHOULDERBURSITIS) | rs116926541 | 19.0285206307203 | 9.37397555205746 | 0.0423635853124335 |
Turnip/swede | Pain (limb, back, neck, head abdominally) (finn-b-PAIN) | rs77004945 | -1.53646037940096 | 0.578355114405189 | 0.0078932153501345 |
Turnip/swede | Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) | rs1276460 | 7.76109994878462 | 3.37824528227554 | 0.0215973243496854 |
Turnip/swede | Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) | rs142228490 | 5.25446101822761 | 2.23730092016991 | 0.0188455841819889 |
Turnip/swede | Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) | rs79218601 | 11.6326117742262 | 4.99527951985973 | 0.0198738566534446 |
Turnip/swede | Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) | All - Inverse variance weighted | 1.71766002781719 | 0.86088844457682 | 0.0460191204392833 |
Turnip/swede | Burn and corrosion of shoulder and upper limb, except wrist and hand (finn-b-ST19_BURN_CORROSION_SHOUL_UPPER_LIMB_WRIST_HAND) | rs11073499 | 19.0079557997217 | 9.34749088723963 | 0.0420038358829806 |
Turnip/swede | Burn and corrosion of shoulder and upper limb, except wrist and hand (finn-b-ST19_BURN_CORROSION_SHOUL_UPPER_LIMB_WRIST_HAND) | rs184498770 | 13.1924761659366 | 4.78876196474754 | 0.0058713230432332 |
Turnip/swede | Burn and corrosion of shoulder and upper limb, except wrist and hand (finn-b-ST19_BURN_CORROSION_SHOUL_UPPER_LIMB_WRIST_HAND) | All - Inverse variance weighted | 5.13740195773522 | 1.8819150342723 | 0.0063357409380846 |
Turnip/swede | Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) | rs145374627 | 10.0571688076389 | 5.05223719969819 | 0.0465208419921054 |
Turnip/swede | Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) | rs146863310 | 10.9790536333719 | 4.18223190726081 | 0.008660669408626 |
Turnip/swede | Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) | rs3906419 | -16.2315264939091 | 6.98767215562788 | 0.0201855798563884 |
Turnip/swede | Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) | rs79218601 | 26.6150785622766 | 10.8554184368467 | 0.0142152243511359 |
Turnip/swede | Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) | All - MR Egger | 7.61060000216103 | 2.8202523562838 | 0.0152209497144563 |
Turnip/swede | Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) | All - Inverse variance weighted | 0.547035348218149 | 0.260563983366408 | 0.0357791798865525 |
Turnip/swede | Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) | All - Inverse variance weighted | 3.45090213646541 | 1.31978074046747 | 0.0089291708086824 |
Turnip/swede | Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) | All - MR Egger | 5.25954968684457 | 2.17019280821534 | 0.0268167712303602 |
Turnip/swede | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | rs141727672 | 73.6527993731257 | 28.2955869923587 | 0.0092417798796708 |
Turnip/swede | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | rs142228490 | 12.8484995701186 | 5.75945179735167 | 0.0256907614651325 |
Turnip/swede | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | rs145374627 | 14.2673664740541 | 6.05275046536876 | 0.0184147762744749 |
Turnip/swede | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | rs4240658 | 18.788593602821 | 9.07729589166821 | 0.0384668815327894 |
Turnip/swede | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | rs79218601 | 27.0365500033718 | 12.242902420932 | 0.0272202459905094 |
Turnip/swede | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | All - Inverse variance weighted | 6.11559662118745 | 2.12552116776005 | 0.0040119302541511 |
Turnip/swede | Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) | All - Inverse variance weighted | -1.21153585948271 | 0.610117141906679 | 0.0470618649044265 |
Turnip/swede | Rheumatoid arthritis (ieu-a-833) | All - Inverse variance weighted | -1.44205740129901 | 0.690870658138083 | 0.0368606225059609 |
Turnip/swede | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | rs148075359 | 5.76649655332331 | 2.54458101876806 | 0.0234399331681647 |
Turnip/swede | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | rs184498770 | 5.22011318197868 | 2.53084829224999 | 0.0391511927625301 |
Turnip/swede | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | All - Inverse variance weighted | 1.37528127421148 | 0.644006531666789 | 0.0327195154060993 |
Turnip/swede | Fractured bone site(s): Ankle (ukb-a-438) | rs11073499 | -0.0812044492387428 | 0.0302420541111225 | 0.0072497278395162 |
Turnip/swede | Fractured bone site(s): Ankle (ukb-a-438) | All - Inverse variance weighted | -0.0149536819876101 | 0.0068741693343436 | 0.0296043588118053 |
Turnip/swede | Diagnoses - main ICD10: M23 Internal derangement of knee (ukb-a-566) | rs145374627 | 0.0899241454836169 | 0.0383324305849573 | 0.0189810710067223 |
Turnip/swede | Diagnoses - main ICD10: M23 Internal derangement of knee (ukb-a-566) | All - MR Egger | 0.034165727789448 | 0.0138420301412513 | 0.0238264298126095 |
Turnip/swede | Diagnoses - main ICD10: M67 Other disorders of synovium and tendon (ukb-a-570) | All - MR Egger | -0.0144032292579364 | 0.0068252100663915 | 0.0490890486537382 |
Turnip/swede | Diagnoses - main ICD10: M51.2 Other specified intervertebral disk displacement (ukb-b-12872) | All - Inverse variance weighted | -0.014828618176058 | 0.0069003859962272 | 0.0316379766156659 |
Turnip/swede | Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) | rs3906419 | -0.0293106470698037 | 0.0132729250022318 | 0.0272231217747318 |
Turnip/swede | Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) | All - Inverse variance weighted | -0.0162705037042328 | 0.0067861072189797 | 0.0165019925669237 |
Turnip/swede | Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) | All - Inverse variance weighted | 0.160159705774629 | 0.0787784226778094 | 0.0420484546013996 |
Turnip/swede | Fractured heel (right) (ukb-b-3499) | rs1276460 | 0.0880514517590513 | 0.0427026947169365 | 0.0392110909389365 |
Turnip/swede | Fractured heel (right) (ukb-b-3499) | rs141727672 | 0.129334709959761 | 0.0417223765040424 | 0.0019359358609811 |
Turnip/swede | Fractured heel (right) (ukb-b-3499) | All - Inverse variance weighted | 0.0233695000613518 | 0.0109738429078819 | 0.033207631385299 |
Turnip/swede | Ankle spacing width (ukb-b-4080) | rs3906419 | -0.631704229124228 | 0.226971115998604 | 0.0053826916648794 |
Turnip/swede | Ankle spacing width (ukb-b-4080) | rs4240658 | -0.480120520726828 | 0.231431797505857 | 0.0380267830495439 |
Turnip/swede | Ankle spacing width (ukb-b-4080) | All - MR Egger | 0.195098718363141 | 0.0885620871408552 | 0.0408667772835149 |
Turnip/swede | Non-cancer illness code, self-reported: sciatica (ukb-b-8194) | All - Inverse variance weighted | -0.02328653779025 | 0.0103531719671489 | 0.0244986479699733 |
Turnip/swede | Ankle spacing width (left) (ukb-e-4100_CSA) | rs1276460 | -3.77811921364693 | 1.79155340188315 | 0.0349574433749546 |
Turnip/swede | Ankle spacing width (left) (ukb-e-4100_CSA) | rs184498770 | 5.52358594100413 | 2.1682078883831 | 0.0108486904232797 |
Turnip/swede | Ankle spacing width (left) (ukb-e-4100_CSA) | rs4240658 | -5.77646102197068 | 1.89093558541514 | 0.0022519834254439 |
Turnip/swede | Ankle spacing width (left) (ukb-e-4100_CSA) | All - MR Egger | 2.08566890025654 | 0.870952810894244 | 0.0376552055626187 |
Turnip/swede | Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) | rs1276460 | 3.96919197888351 | 1.95406374345034 | 0.0422296406354306 |
Turnip/swede | Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) | All - MR Egger | -1.96811802585021 | 0.849531005372254 | 0.0430130242251274 |