ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Turnip/swede (ukb-b-5008)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Turnip/swede (👉 📊) Heel bone mineral density (ebi-a-GCST006288) MR Egger 20 -0.294409013 0.131976389 0.03865774
Turnip/swede (👉 📊) Juvenile rheumatoid arthritis (ebi-a-GCST90018653) Inverse variance weighted 7 -4.960590572 2.39380055 0.038240677
Turnip/swede (👉 📊) Spine arthritis or spondylitis (ebi-a-GCST90038657) Inverse variance weighted 18 -0.009834521 0.004477952 0.028076954
Turnip/swede (👉 📊) Other joint disorder (ebi-a-GCST90038688) Weighted median 18 -0.015835895 0.00640607 0.013435427
Turnip/swede (👉 📊) Cervical spondylosis (ebi-a-GCST90038693) Weighted median 18 -0.01201227 0.005713584 0.035517784
Turnip/swede (👉 📊) Cervical spondylosis (ebi-a-GCST90038693) Inverse variance weighted 18 -0.008163334 0.004044168 0.043534548
Turnip/swede (👉 📊) Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) Inverse variance weighted 19 6.661857728 3.224129593 0.038804881
Turnip/swede (👉 📊) Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) Inverse variance weighted 19 6.634464521 3.223268076 0.039560992
Turnip/swede (👉 📊) Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) Inverse variance weighted 19 -3.579524136 1.756316249 0.0415413
Turnip/swede (👉 📊) Chondromalacia (finn-b-M13_CHONDROMALACIA) MR Egger 19 5.283012294 2.474145272 0.047585651
Turnip/swede (👉 📊) Osteomyelitis (finn-b-M13_OSTEOMYELITIS) MR Egger 19 -4.38429566 1.754998506 0.023033612
Turnip/swede (👉 📊) Osteonecrosis (finn-b-M13_OSTEONECROSIS) MR Egger 19 -6.127233996 2.088124365 0.009262867
Turnip/swede (👉 📊) Osteonecrosis (finn-b-M13_OSTEONECROSIS) Weighted median 19 -5.545539359 1.808430802 0.002165863
Turnip/swede (👉 📊) Osteonecrosis (finn-b-M13_OSTEONECROSIS) Inverse variance weighted 19 -4.430301566 1.270099171 0.000486368
Turnip/swede (👉 📊) Osteonecrosis (finn-b-M13_OSTEONECROSIS) Weighted mode 19 -6.124115568 2.514415676 0.02548981
Turnip/swede (👉 📊) Bursitis of shoulder (finn-b-M13_SHOULDERBURSITIS) Weighted median 19 4.999882058 2.449388719 0.041223253
Turnip/swede (👉 📊) Pain (limb, back, neck, head abdominally) (finn-b-PAIN) Weighted median 19 -0.468124701 0.215109501 0.029539126
Turnip/swede (👉 📊) Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) Inverse variance weighted 19 1.717660028 0.860888445 0.04601912
Turnip/swede (👉 📊) Burn and corrosion of shoulder and upper limb, except wrist and hand (finn-b-ST19_BURN_CORROSION_SHOUL_UPPER_LIMB_WRIST_HAND) Inverse variance weighted 19 5.137401958 1.881915034 0.006335741
Turnip/swede (👉 📊) Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) MR Egger 19 7.610600002 2.820252356 0.01522095
Turnip/swede (👉 📊) Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) Inverse variance weighted 19 0.547035348 0.260563983 0.03577918
Turnip/swede (👉 📊) Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) MR Egger 19 5.259549687 2.170192808 0.026816771
Turnip/swede (👉 📊) Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) Inverse variance weighted 19 3.450902136 1.31978074 0.008929171
Turnip/swede (👉 📊) Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) Weighted median 19 6.027765319 2.727125932 0.027084377
Turnip/swede (👉 📊) Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) Inverse variance weighted 19 6.115596621 2.125521168 0.00401193
Turnip/swede (👉 📊) Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) Inverse variance weighted 19 -1.211535859 0.610117142 0.047061865
Turnip/swede (👉 📊) Rheumatoid arthritis (ieu-a-833) Inverse variance weighted 4 -1.442057401 0.690870658 0.036860623
Turnip/swede (👉 📊) Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) Inverse variance weighted 18 1.375281274 0.644006532 0.032719515
Turnip/swede (👉 📊) Fractured bone site(s): Ankle (ukb-a-438) Inverse variance weighted 20 -0.014953682 0.006874169 0.029604359
Turnip/swede (👉 📊) Diagnoses - main ICD10: M23 Internal derangement of knee (ukb-a-566) MR Egger 20 0.034165728 0.01384203 0.02382643
Turnip/swede (👉 📊) Diagnoses - main ICD10: M67 Other disorders of synovium and tendon (ukb-a-570) MR Egger 20 -0.014403229 0.00682521 0.049089049
Turnip/swede (👉 📊) Diagnoses - main ICD10: M51.2 Other specified intervertebral disk displacement (ukb-b-12872) Inverse variance weighted 3 -0.014828618 0.006900386 0.031637977
Turnip/swede (👉 📊) Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) Inverse variance weighted 4 -0.016270504 0.006786107 0.016501993
Turnip/swede (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) Inverse variance weighted 20 0.160159706 0.078778423 0.042048455
Turnip/swede (👉 📊) Fractured heel (right) (ukb-b-3499) Inverse variance weighted 20 0.0233695 0.010973843 0.033207631
Turnip/swede (👉 📊) Ankle spacing width (ukb-b-4080) MR Egger 20 0.195098718 0.088562087 0.040866777
Turnip/swede (👉 📊) Non-cancer illness code, self-reported: sciatica (ukb-b-8194) Weighted median 4 -0.027797693 0.013046847 0.033121592
Turnip/swede (👉 📊) Non-cancer illness code, self-reported: sciatica (ukb-b-8194) Inverse variance weighted 4 -0.023286538 0.010353172 0.024498648
Turnip/swede (👉 📊) Ankle spacing width (left) (ukb-e-4100_CSA) MR Egger 12 2.0856689 0.870952811 0.037655206
Turnip/swede (👉 📊) Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) MR Egger 12 -1.968118026 0.849531005 0.043013024

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Turnip/swede Heel bone mineral density (ebi-a-GCST006288) rs142228490 0.871901737743586 0.418276191602451 0.037113620479863
Turnip/swede Heel bone mineral density (ebi-a-GCST006288) rs4240658 0.734554508054842 0.344587033354534 0.0330319157231814
Turnip/swede Heel bone mineral density (ebi-a-GCST006288) All - MR Egger -0.294409013083958 0.131976388901946 0.0386577404001793
Turnip/swede Juvenile rheumatoid arthritis (ebi-a-GCST90018653) All - Inverse variance weighted -4.96059057173044 2.39380055004574 0.0382406771303106
Turnip/swede Spine arthritis or spondylitis (ebi-a-GCST90038657) All - Inverse variance weighted -0.0098345210614109 0.0044779522167377 0.0280769539172611
Turnip/swede Cervical spondylosis (ebi-a-GCST90038693) rs1276460 -0.0383542134499468 0.0173448764921404 0.027017111954528
Turnip/swede Cervical spondylosis (ebi-a-GCST90038693) All - Inverse variance weighted -0.0081633343278282 0.0040441679265206 0.0435345484301645
Turnip/swede Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) rs16826913 24.8354788809942 12.6569832988123 0.0497396981510233
Turnip/swede Benign neoplasm: Bone and articular cartilage, unspecified (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS) All - Inverse variance weighted 6.66185772800345 3.22412959272896 0.0388048811608334
Turnip/swede Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) rs16826913 25.061613486799 12.6864791169608 0.0482161354004117
Turnip/swede Benign neoplasm: Bone and articular cartilage, unspecified (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_NOS_EXALLC) All - Inverse variance weighted 6.63446452133588 3.22326807642278 0.0395609918146653
Turnip/swede Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) rs142228490 -10.7166714076139 5.19053813479418 0.0389556389298303
Turnip/swede Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) rs75193468 -31.7778113691822 13.243582584982 0.0164180386670244
Turnip/swede Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) All - Inverse variance weighted -3.57952413629975 1.75631624900925 0.0415413001236751
Turnip/swede Chondromalacia (finn-b-M13_CHONDROMALACIA) All - MR Egger 5.28301229368982 2.47414527215006 0.0475856512146828
Turnip/swede Osteomyelitis (finn-b-M13_OSTEOMYELITIS) rs11073499 10.5054947806365 5.29969349410461 0.0474475236468978
Turnip/swede Osteomyelitis (finn-b-M13_OSTEOMYELITIS) rs77004945 -8.23883229011165 4.02229613527835 0.0405315109591339
Turnip/swede Osteomyelitis (finn-b-M13_OSTEOMYELITIS) All - MR Egger -4.38429565988781 1.75499850624882 0.023033612020374
Turnip/swede Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs142228490 -7.85931851813972 3.94723805201405 0.0464706509854021
Turnip/swede Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs146863310 -8.0086868866554 3.43176495004299 0.0196117869338221
Turnip/swede Osteonecrosis (finn-b-M13_OSTEONECROSIS) All - Inverse variance weighted -4.43030156584211 1.27009917142417 0.000486367771802
Turnip/swede Osteonecrosis (finn-b-M13_OSTEONECROSIS) All - MR Egger -6.1272339958765 2.08812436536348 0.0092628673472604
Turnip/swede Bursitis of shoulder (finn-b-M13_SHOULDERBURSITIS) rs116926541 19.0285206307203 9.37397555205746 0.0423635853124335
Turnip/swede Pain (limb, back, neck, head abdominally) (finn-b-PAIN) rs77004945 -1.53646037940096 0.578355114405189 0.0078932153501345
Turnip/swede Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) rs1276460 7.76109994878462 3.37824528227554 0.0215973243496854
Turnip/swede Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) rs142228490 5.25446101822761 2.23730092016991 0.0188455841819889
Turnip/swede Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) rs79218601 11.6326117742262 4.99527951985973 0.0198738566534446
Turnip/swede Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) All - Inverse variance weighted 1.71766002781719 0.86088844457682 0.0460191204392833
Turnip/swede Burn and corrosion of shoulder and upper limb, except wrist and hand (finn-b-ST19_BURN_CORROSION_SHOUL_UPPER_LIMB_WRIST_HAND) rs11073499 19.0079557997217 9.34749088723963 0.0420038358829806
Turnip/swede Burn and corrosion of shoulder and upper limb, except wrist and hand (finn-b-ST19_BURN_CORROSION_SHOUL_UPPER_LIMB_WRIST_HAND) rs184498770 13.1924761659366 4.78876196474754 0.0058713230432332
Turnip/swede Burn and corrosion of shoulder and upper limb, except wrist and hand (finn-b-ST19_BURN_CORROSION_SHOUL_UPPER_LIMB_WRIST_HAND) All - Inverse variance weighted 5.13740195773522 1.8819150342723 0.0063357409380846
Turnip/swede Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) rs145374627 10.0571688076389 5.05223719969819 0.0465208419921054
Turnip/swede Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) rs146863310 10.9790536333719 4.18223190726081 0.008660669408626
Turnip/swede Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) rs3906419 -16.2315264939091 6.98767215562788 0.0201855798563884
Turnip/swede Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) rs79218601 26.6150785622766 10.8554184368467 0.0142152243511359
Turnip/swede Dislocation, sprain and strain of joint and ligaments of hip (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINT_LIGAM_HIP) All - MR Egger 7.61060000216103 2.8202523562838 0.0152209497144563
Turnip/swede Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) All - Inverse variance weighted 0.547035348218149 0.260563983366408 0.0357791798865525
Turnip/swede Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) All - Inverse variance weighted 3.45090213646541 1.31978074046747 0.0089291708086824
Turnip/swede Injury of nerves at wrist and hand level (finn-b-ST19_INJURY_NERVES_WRIST_HAND_LEVEL) All - MR Egger 5.25954968684457 2.17019280821534 0.0268167712303602
Turnip/swede Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) rs141727672 73.6527993731257 28.2955869923587 0.0092417798796708
Turnip/swede Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) rs142228490 12.8484995701186 5.75945179735167 0.0256907614651325
Turnip/swede Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) rs145374627 14.2673664740541 6.05275046536876 0.0184147762744749
Turnip/swede Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) rs4240658 18.788593602821 9.07729589166821 0.0384668815327894
Turnip/swede Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) rs79218601 27.0365500033718 12.242902420932 0.0272202459905094
Turnip/swede Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) All - Inverse variance weighted 6.11559662118745 2.12552116776005 0.0040119302541511
Turnip/swede Temporomandibular joint disorders (finn-b-TEMPOROMANDIB) All - Inverse variance weighted -1.21153585948271 0.610117141906679 0.0470618649044265
Turnip/swede Rheumatoid arthritis (ieu-a-833) All - Inverse variance weighted -1.44205740129901 0.690870658138083 0.0368606225059609
Turnip/swede Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) rs148075359 5.76649655332331 2.54458101876806 0.0234399331681647
Turnip/swede Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) rs184498770 5.22011318197868 2.53084829224999 0.0391511927625301
Turnip/swede Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) All - Inverse variance weighted 1.37528127421148 0.644006531666789 0.0327195154060993
Turnip/swede Fractured bone site(s): Ankle (ukb-a-438) rs11073499 -0.0812044492387428 0.0302420541111225 0.0072497278395162
Turnip/swede Fractured bone site(s): Ankle (ukb-a-438) All - Inverse variance weighted -0.0149536819876101 0.0068741693343436 0.0296043588118053
Turnip/swede Diagnoses - main ICD10: M23 Internal derangement of knee (ukb-a-566) rs145374627 0.0899241454836169 0.0383324305849573 0.0189810710067223
Turnip/swede Diagnoses - main ICD10: M23 Internal derangement of knee (ukb-a-566) All - MR Egger 0.034165727789448 0.0138420301412513 0.0238264298126095
Turnip/swede Diagnoses - main ICD10: M67 Other disorders of synovium and tendon (ukb-a-570) All - MR Egger -0.0144032292579364 0.0068252100663915 0.0490890486537382
Turnip/swede Diagnoses - main ICD10: M51.2 Other specified intervertebral disk displacement (ukb-b-12872) All - Inverse variance weighted -0.014828618176058 0.0069003859962272 0.0316379766156659
Turnip/swede Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) rs3906419 -0.0293106470698037 0.0132729250022318 0.0272231217747318
Turnip/swede Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) All - Inverse variance weighted -0.0162705037042328 0.0067861072189797 0.0165019925669237
Turnip/swede Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) All - Inverse variance weighted 0.160159705774629 0.0787784226778094 0.0420484546013996
Turnip/swede Fractured heel (right) (ukb-b-3499) rs1276460 0.0880514517590513 0.0427026947169365 0.0392110909389365
Turnip/swede Fractured heel (right) (ukb-b-3499) rs141727672 0.129334709959761 0.0417223765040424 0.0019359358609811
Turnip/swede Fractured heel (right) (ukb-b-3499) All - Inverse variance weighted 0.0233695000613518 0.0109738429078819 0.033207631385299
Turnip/swede Ankle spacing width (ukb-b-4080) rs3906419 -0.631704229124228 0.226971115998604 0.0053826916648794
Turnip/swede Ankle spacing width (ukb-b-4080) rs4240658 -0.480120520726828 0.231431797505857 0.0380267830495439
Turnip/swede Ankle spacing width (ukb-b-4080) All - MR Egger 0.195098718363141 0.0885620871408552 0.0408667772835149
Turnip/swede Non-cancer illness code, self-reported: sciatica (ukb-b-8194) All - Inverse variance weighted -0.02328653779025 0.0103531719671489 0.0244986479699733
Turnip/swede Ankle spacing width (left) (ukb-e-4100_CSA) rs1276460 -3.77811921364693 1.79155340188315 0.0349574433749546
Turnip/swede Ankle spacing width (left) (ukb-e-4100_CSA) rs184498770 5.52358594100413 2.1682078883831 0.0108486904232797
Turnip/swede Ankle spacing width (left) (ukb-e-4100_CSA) rs4240658 -5.77646102197068 1.89093558541514 0.0022519834254439
Turnip/swede Ankle spacing width (left) (ukb-e-4100_CSA) All - MR Egger 2.08566890025654 0.870952810894244 0.0376552055626187
Turnip/swede Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) rs1276460 3.96919197888351 1.95406374345034 0.0422296406354306
Turnip/swede Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) All - MR Egger -1.96811802585021 0.849531005372254 0.0430130242251274