ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Pork | Heel bone mineral density (ebi-a-GCST006979) | rs11015253 | 0.463990789515188 | 0.134404209906528 | 0.0005560265799747 |
| Pork | Heel bone mineral density (ebi-a-GCST006979) | rs11660997 | 0.445175068019565 | 0.145368855953553 | 0.0021958252580822 |
| Pork | Heel bone mineral density (ebi-a-GCST006979) | rs79938133 | -0.369753332618814 | 0.137922013117876 | 0.0073427305230698 |
| Pork | Heel bone mineral density (ebi-a-GCST006979) | All - MR Egger | -0.224375558799903 | 0.0817248106415238 | 0.0166806057046558 |
| Pork | Osteoprotegerin levels (ebi-a-GCST90012002) | rs11015253 | 1.72433733926337 | 0.741254770841876 | 0.0200056903678772 |
| Pork | Osteoprotegerin levels (ebi-a-GCST90012002) | rs74654606 | 2.3547485534536 | 0.933779598783326 | 0.0116776273732625 |
| Pork | Bone mineral density (ebi-a-GCST90014022) | rs11015253 | 0.348176828691291 | 0.149995268586569 | 0.0202732430486516 |
| Pork | Bone mineral density (ebi-a-GCST90014022) | rs11660997 | 0.447134651608052 | 0.160337811126528 | 0.0052919451717842 |
| Pork | Bone mineral density (ebi-a-GCST90014022) | rs12200757 | 0.781121570541787 | 0.159157865572494 | 9.20842452750043e-07 |
| Pork | Bone mineral density (ebi-a-GCST90014022) | rs72715663 | -0.430730308976875 | 0.158882411789603 | 0.0067080510869978 |
| Pork | Bone mineral density (ebi-a-GCST90014022) | rs79938133 | -0.430017201180012 | 0.153315224362072 | 0.005034917505002 |
| Pork | Bone mineral density (ebi-a-GCST90014022) | All - MR Egger | -0.254814103610011 | 0.109220753224857 | 0.0363580180249017 |
| Pork | Heel bone mineral density T score (ebi-a-GCST90025982) | rs11015253 | 0.420719385126539 | 0.136640591321536 | 0.0020768135315829 |
| Pork | Heel bone mineral density T score (ebi-a-GCST90025982) | rs79938133 | -0.414047688909895 | 0.140357587758523 | 0.0031782665763027 |
| Pork | Heel bone mineral density T score (ebi-a-GCST90025982) | All - MR Egger | -0.587619477910081 | 0.130588690034076 | 0.0108244309190308 |
| Pork | Heel bone mineral density (ebi-a-GCST90029004) | rs11015253 | 0.390954063232712 | 0.136200044159859 | 0.0040990089930577 |
| Pork | Heel bone mineral density (ebi-a-GCST90029004) | rs11660997 | 0.431260319207485 | 0.147107521297294 | 0.0033722144466363 |
| Pork | Heel bone mineral density (ebi-a-GCST90029004) | rs12200757 | 0.792962642900964 | 0.142645011907039 | 2.71335357902063e-08 |
| Pork | Heel bone mineral density (ebi-a-GCST90029004) | rs79938133 | -0.415216104099644 | 0.138679813826656 | 0.0027528906495954 |
| Pork | Heel bone mineral density (ebi-a-GCST90029004) | All - MR Egger | -0.247680317138172 | 0.107646000942956 | 0.0361628734280345 |
| Pork | Fractures (ebi-a-GCST90038703) | rs11015253 | -0.0455341765763492 | 0.019792553806685 | 0.0214158881626653 |
| Pork | Fractures (ebi-a-GCST90038703) | All - Inverse variance weighted | -0.0103272075755275 | 0.0047732873251543 | 0.030499517501458 |
| Pork | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | rs11015253 | -0.0349211956807453 | 0.0136384569283664 | 0.0104523279809973 |
| Pork | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | rs2033773 | -0.0386945424887151 | 0.014429358907654 | 0.0073259270881259 |
| Pork | Fracture of pelvis or lower limb (ebi-a-GCST90038706) | All - Inverse variance weighted | -0.0082926679069465 | 0.0042121332454273 | 0.0489809724346838 |
| Pork | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | rs11015253 | -20.5501056682333 | 9.72568316352816 | 0.0346030812157579 |
| Pork | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | rs146286612 | -11.5563349125 | 5.66271713541112 | 0.0412731377528624 |
| Pork | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | All - Inverse variance weighted | -6.31179948546331 | 2.29644135607234 | 0.0059866215963337 |
| Pork | Calcific tendinitis (finn-b-M13_CALCTENDINITIS) | All - MR Egger | -10.4044615351451 | 4.45825896257493 | 0.035030941487792 |
| Pork | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | rs114925259 | -9.99967826003024 | 4.80250528189784 | 0.0373260729829897 |
| Pork | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | All - Inverse variance weighted | -2.16395857312012 | 0.942277579912209 | 0.0216462114823621 |
| Pork | Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) | rs79938133 | -3.13451533610825 | 0.959330366320125 | 0.0010854048506576 |
| Pork | Rheumatoid arthritis (M13_RHEUMA) (finn-b-M13_RHEUMA) | All - MR Egger | -1.62331336695466 | 0.69260156516965 | 0.0343676245032988 |
| Pork | Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) | rs79938133 | -3.21006699499426 | 0.932975136476165 | 0.0005802587004076 |
| Pork | Rheumatoid arthritis (M13_RHEUMA_INCLAVO) (finn-b-M13_RHEUMA_INCLAVO) | All - MR Egger | -1.64732397737426 | 0.675584413442082 | 0.0286781194205411 |
| Pork | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | rs111890949 | -2.32962671241841 | 0.980394489802232 | 0.0174913344894323 |
| Pork | Disorders of synovium and tendon (finn-b-M13_SYNOTEND) | All - MR Egger | -1.43148358462667 | 0.523957020549437 | 0.0162055485215449 |
| Pork | Collapsed vertebra, not elsewhere classified (finn-b-M13_VERTEBCOLLAPSE) | rs146286612 | 21.5076681618694 | 7.69884097566017 | 0.0052121016078879 |
| Pork | Collapsed vertebra, not elsewhere classified (finn-b-M13_VERTEBCOLLAPSE) | All - Inverse variance weighted | 5.6399019460824 | 2.87405172969989 | 0.0497214851959991 |
| Pork | Collapsed vertebra, not elsewhere classified (finn-b-M13_VERTEBCOLLAPSE) | All - MR Egger | 12.4052992061905 | 5.6386041345229 | 0.0450947472687058 |
| Pork | Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS) | rs12200757 | 4.1295327559024 | 1.66896451636311 | 0.0133494441571982 |
| Pork | Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS) | rs79938133 | -3.73892860719638 | 1.10340562280044 | 0.0007026705237088 |
| Pork | Seropositive rheumatoid arthritis (finn-b-RHEUMA_SEROPOS) | All - MR Egger | -2.25644991475734 | 0.908164311198242 | 0.0262338551322977 |
| Pork | Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) | rs12200757 | 3.89864833664268 | 1.66896451636311 | 0.019492889605228 |
| Pork | Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) | rs79938133 | -3.7916390668843 | 1.10164860747751 | 0.0005778866171674 |
| Pork | Other/unspecified seropositiverheumatoid arthritis (finn-b-RHEUMA_SEROPOS_OTH) | All - MR Egger | -2.17529296545103 | 0.898926189458664 | 0.0297146703261464 |
| Pork | Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) | rs12200757 | 4.10974266282299 | 1.65577112097684 | 0.0130620984607576 |
| Pork | Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) | rs79938133 | -3.7283865152588 | 1.09462054618578 | 0.0006589815324385 |
| Pork | Seropositive rheumatoid arthritis, wide (finn-b-RHEUMA_SEROPOS_WIDE) | All - MR Egger | -2.26004498334782 | 0.91041935041027 | 0.0263457191393664 |
| Pork | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | rs79938133 | -10.5543910448443 | 5.14102683489503 | 0.040075162968716 |
| Pork | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | All - Inverse variance weighted | -4.27295281770154 | 1.9315365995936 | 0.0269525788232335 |
| Pork | Burn and corrosion of ankle and foot (finn-b-ST19_BURN_CORROSION_ANKLE_FOOT) | All - MR Egger | -8.23610204190772 | 3.76094717151465 | 0.0459616195734125 |
| Pork | Fracture of foot, except ankle (finn-b-ST19_FRACT_FOOT_ANKLE) | rs12200757 | -4.1493228489818 | 1.81409186561207 | 0.022179909327525 |
| Pork | Fracture of foot, except ankle (finn-b-ST19_FRACT_FOOT_ANKLE) | All - Inverse variance weighted | -0.878969579666117 | 0.443275829732108 | 0.0473791206620402 |
| Pork | Fracture of lumbar spine and pelvis (finn-b-ST19_FRACT_LUMBAR_SPINE_PELVIS) | All - Inverse variance weighted | 1.09864282785836 | 0.492296651246535 | 0.0256368942516372 |
| Pork | Injuries to the abdomen, lower back, lumbar spine and pelvis (finn-b-ST19_INJURI_ABDOMEN_LOWER_BACK_LUMBAR_SPINE_PELVIS) | All - Inverse variance weighted | 0.875391112728108 | 0.342995585603646 | 0.0107047041018862 |
| Pork | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | rs115804082 | 2.27229995276551 | 1.01118494366255 | 0.0246294500451123 |
| Pork | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | All - Inverse variance weighted | 0.494619792969587 | 0.241781092997291 | 0.0407825525477005 |
| Pork | Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) | rs16904846 | 30.5536697524708 | 14.3371864712588 | 0.0330826761299188 |
| Pork | Injury of muscle and tendon at ankle and foot level (finn-b-ST19_INJURY_MUSCLE_TENDON_ANKLE_FOOT_LEVEL) | All - MR Egger | 7.54383388287755 | 2.88626622418956 | 0.0204251480129929 |
| Pork | Injury of muscle and tendon at wrist and hand level (finn-b-ST19_INJURY_MUSCLE_TENDON_WRIST_HAND_LEVEL) | rs11660997 | 5.75937739812568 | 2.40297038145217 | 0.0165401131645474 |
| Pork | Injury of muscle and tendon at wrist and hand level (finn-b-ST19_INJURY_MUSCLE_TENDON_WRIST_HAND_LEVEL) | rs79938133 | -4.02180807418821 | 1.48643496319931 | 0.0068165976412493 |
| Pork | Injury of muscle and tendon at wrist and hand level (finn-b-ST19_INJURY_MUSCLE_TENDON_WRIST_HAND_LEVEL) | All - MR Egger | -2.61137208828784 | 1.08423483878099 | 0.0303706680273287 |
| Pork | Superficial injury of shoulder and upper arm (finn-b-ST19_SUPERF_INJURY_SHOUL_UPPER_ARM) | rs146286612 | -3.70571309545723 | 1.7697000229286 | 0.0362619309734285 |
| Pork | Superficial injury of shoulder and upper arm (finn-b-ST19_SUPERF_INJURY_SHOUL_UPPER_ARM) | All - MR Egger | -3.00773098342455 | 1.36795491518814 | 0.0452097914487799 |
| Pork | Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) | rs79938133 | -0.0374852191085958 | 0.0190381395316149 | 0.0489583849719083 |
| Pork | Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) | All - MR Egger | -0.0217458333367778 | 0.0091674498339055 | 0.0314957707711164 |
| Pork | Non-cancer illness code self-reported: joint disorder (ukb-a-86) | All - MR Egger | -0.0133510846272691 | 0.0060656229157281 | 0.043802935426401 |
| Pork | Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) | All - MR Egger | -0.294024228677422 | 0.127811179645237 | 0.0361922566400212 |
| Pork | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | rs11015253 | 0.178669736828271 | 0.0622312294314944 | 0.0040909488757156 |
| Pork | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | rs11660997 | 0.151480927391537 | 0.0667245963397335 | 0.0231929527479361 |
| Pork | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | rs4770147 | 0.125739359417104 | 0.0593406716022383 | 0.0340954856219919 |
| Pork | Pain type(s) experienced in last month: Knee pain (ukb-b-16254) | All - Inverse variance weighted | 0.0439966761459388 | 0.0168958110932761 | 0.0092143010441623 |
| Pork | Operative procedures - secondary OPCS: W85.2 Endoscopic irrigation of knee joint (ukb-b-19546) | All - Inverse variance weighted | -0.0079689911057714 | 0.0037753967400417 | 0.0347921558624831 |
| Pork | Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) | rs11015253 | 0.509134782197268 | 0.250547266820175 | 0.042144470112496 |
| Pork | Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) | All - MR Egger | -0.319580054710225 | 0.12386905418123 | 0.0209153823379635 |
| Pork | Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) | rs11660997 | 0.447513700806933 | 0.200565860767245 | 0.0256642026509638 |
| Pork | Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) | rs12200757 | 0.912587158868271 | 0.195825609699784 | 3.15897165733437e-06 |
| Pork | Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) | All - MR Egger | -0.238022439625724 | 0.111188549857651 | 0.0491318024880831 |
| Pork | Operation code: ankle surgery (ukb-b-4274) | All - Inverse variance weighted | 0.0085904352037319 | 0.0040751592769373 | 0.0350310011503156 |
| Pork | Heel bone mineral density (BMD) (right) (ukb-b-4657) | rs12200757 | 0.526325441483993 | 0.264113304879577 | 0.0462831661578082 |
| Pork | Heel bone mineral density (BMD) (right) (ukb-b-4657) | All - MR Egger | -0.310879215832922 | 0.123891059148294 | 0.0240601268226463 |
| Pork | Heel bone mineral density (BMD) (ukb-b-8875) | rs11660997 | 0.428743401520848 | 0.200534854697807 | 0.0325167909206136 |
| Pork | Heel bone mineral density (BMD) (ukb-b-8875) | rs12200757 | 0.913424939475299 | 0.195777453806624 | 3.07674600260216e-06 |
| Pork | Heel bone mineral density (BMD) (ukb-b-8875) | All - MR Egger | -0.241254938080485 | 0.110032172468387 | 0.044520816828212 |
| Pork | Adhesive capsulitis of shoulder (ukb-d-M13_ADHCAPSULITIS) | All - Inverse variance weighted | -0.0053119622165179 | 0.0024458429347798 | 0.0298682672104807 |
| Pork | Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) | All - Inverse variance weighted | 2.81164967055667 | 1.24341681344842 | 0.0237451044450372 |
| Pork | Osteoarthrosis (ukb-e-740_CSA) | rs11015253 | 11.5288773933066 | 5.20034907316868 | 0.0266269879396096 |
| Pork | Osteoarthrosis (ukb-e-740_CSA) | rs79938133 | 3.18722579579617 | 1.49838266739524 | 0.0334108869255357 |
| Pork | Osteoarthrosis (ukb-e-740_CSA) | All - MR Egger | 4.9523764742195 | 1.8726284306598 | 0.0245389307403245 |
| Pork | Pain in joint (ukb-e-745_AFR) | All - Inverse variance weighted | 3.4546046807446 | 1.74906480731299 | 0.0482550636895943 |
| Pork | M51 Other intervertebral disk disorders (ukb-e-M51_CSA) | All - Inverse variance weighted | -3.18123863704153 | 1.55313445041351 | 0.0405335548431605 |