ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Oat crunch | Rheumatoid arthritis (ebi-a-GCST002318) | rs12569768 | -5.06002729644856 | 2.05513633704891 | 0.0138111884689842 |
| Oat crunch | Rheumatoid arthritis (ebi-a-GCST002318) | All - MR Egger | 3.53742427134788 | 1.48923686558695 | 0.0492191435552482 |
| Oat crunch | Osteoarthritis of the hip (hospital diagnosed) (ebi-a-GCST005810) | rs12593521 | 8.65698257606717 | 3.38662767555289 | 0.0105814651211597 |
| Oat crunch | Osteoarthritis of the hip (hospital diagnosed) (ebi-a-GCST005810) | All - Inverse variance weighted | 2.7040467732085 | 1.08215144632891 | 0.012462542501233 |
| Oat crunch | Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) | rs12593521 | 5.78837590688837 | 2.05353228708357 | 0.0048212384428668 |
| Oat crunch | Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) | rs151195045 | 4.33403364531347 | 1.99277566251536 | 0.029639647453027 |
| Oat crunch | Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) | All - Inverse variance weighted | 2.12713786487559 | 0.65910466670457 | 0.0012495815468327 |
| Oat crunch | Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) | All - MR Egger | 3.31492739928652 | 1.47280416373146 | 0.0481176055478205 |
| Oat crunch | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | rs12593521 | 4.44814482615872 | 1.6928812911649 | 0.0086000023236344 |
| Oat crunch | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | rs151195045 | 3.19485612001881 | 1.61609377607208 | 0.0480529114616726 |
| Oat crunch | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | rs56160326 | 4.48084075771992 | 1.89900394562621 | 0.018295920503638 |
| Oat crunch | Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) | All - Inverse variance weighted | 1.65634277266489 | 0.564809438463114 | 0.0033616997827429 |
| Oat crunch | Heel bone mineral density (ebi-a-GCST006979) | rs10434441 | 0.642849257481487 | 0.22889088091001 | 0.0049766657157432 |
| Oat crunch | Heel bone mineral density (ebi-a-GCST006979) | rs141655467 | -0.920289109176755 | 0.218100203629529 | 2.44768553568831e-05 |
| Oat crunch | Heel bone mineral density (ebi-a-GCST006979) | rs145470700 | 0.553606956423858 | 0.208596192539855 | 0.007955212046534 |
| Oat crunch | Neck circumference (BMI adjusted) (ebi-a-GCST90017136) | rs116849846 | 10.0407647066046 | 3.72346303549722 | 0.0070047164537122 |
| Oat crunch | Neck circumference (BMI adjusted) (ebi-a-GCST90017136) | rs151195045 | 10.0382264156668 | 2.95420414726272 | 0.0006789379904168 |
| Oat crunch | Neck circumference (BMI adjusted) (ebi-a-GCST90017136) | All - MR Egger | 5.96635749257444 | 2.00938334601606 | 0.0140638939569796 |
| Oat crunch | Neck circumference (BMI adjusted) (ebi-a-GCST90017138) | rs116849846 | 10.3047530174478 | 4.94210674950579 | 0.0370608443313977 |
| Oat crunch | Neck circumference (BMI adjusted) (ebi-a-GCST90017138) | rs151195045 | 10.5729411586245 | 3.83781077924245 | 0.0058702771835487 |
| Oat crunch | Neck circumference (BMI adjusted) (ebi-a-GCST90017138) | All - MR Egger | 6.23694585254383 | 2.55969463930343 | 0.0350523977486012 |
| Oat crunch | Osteoarthritis (ebi-a-GCST90038686) | All - Inverse variance weighted | -0.042642444280872 | 0.018610290224298 | 0.0219439373318501 |
| Oat crunch | Other joint disorder (ebi-a-GCST90038688) | rs13220965 | -0.0838991229809753 | 0.0249414980114732 | 0.0007686704835473 |
| Oat crunch | Other joint disorder (ebi-a-GCST90038688) | All - MR Egger | 0.0480540010934362 | 0.0152366354366027 | 0.0102656223806505 |
| Oat crunch | Malignant neoplasm of bone and articular cartilage (finn-b-C3_BONE_CARTILAGE) | rs141655467 | -33.5205531562577 | 16.9169146769899 | 0.0475373040905204 |
| Oat crunch | Malignant neoplasm of bone and articular cartilage (finn-b-C3_BONE_CARTILAGE) | All - Inverse variance weighted | -10.1349248867577 | 4.76481787851166 | 0.0334173410361231 |
| Oat crunch | Malignant neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-C3_BONE_CARTILAGE_EXALLC) | rs141655467 | -33.5474054017767 | 16.8900624314708 | 0.0470087328302687 |
| Oat crunch | Malignant neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-C3_BONE_CARTILAGE_EXALLC) | All - Inverse variance weighted | -10.2123202086344 | 4.76510518166854 | 0.0321013077066476 |
| Oat crunch | Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) | All - MR Egger | -7.60677398395586 | 3.32894773253723 | 0.0431523899160753 |
| Oat crunch | Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) | All - MR Egger | -7.68251630265334 | 3.32979606544077 | 0.0415025158117762 |
| Oat crunch | Melanocytic naevi of upper limb, including shoulder (finn-b-CD2_BENIGN_MELANOCYTIC_UPPERLIMB) | rs10434441 | 20.5423498293289 | 10.3197488287063 | 0.0465263962663218 |
| Oat crunch | Melanocytic naevi of upper limb, including shoulder (finn-b-CD2_BENIGN_MELANOCYTIC_UPPERLIMB) | All - Inverse variance weighted | 8.05886349454777 | 3.1900621887599 | 0.011529060946588 |
| Oat crunch | Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) | All - Inverse variance weighted | 0.859106581139344 | 0.420257992075498 | 0.0409302231988673 |
| Oat crunch | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | rs72784689 | -20.4166907732757 | 8.10624907591332 | 0.0117810375920488 |
| Oat crunch | Other disorders of bone density and structure (finn-b-M13_BONEDENSOTH) | All - Inverse variance weighted | -5.86345629332293 | 2.80332084698868 | 0.0364733413531112 |
| Oat crunch | Cervicalgia (finn-b-M13_CERVICALGIA) | All - Inverse variance weighted | -1.84303141427036 | 0.932311282571905 | 0.0480595757705487 |
| Oat crunch | Cervicalgia (finn-b-M13_CERVICALGIA) | All - MR Egger | -5.761668534356 | 2.03542581454827 | 0.0163518283928545 |
| Oat crunch | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | rs12593521 | -4.42895886295968 | 2.12027449461042 | 0.0367202305367552 |
| Oat crunch | Internar derangement of knee (finn-b-M13_KNEEDERANGEMENTS) | All - MR Egger | -2.49073017603305 | 0.941842172614602 | 0.0228080088350899 |
| Oat crunch | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | rs10434441 | -14.7223117650436 | 6.72527918961048 | 0.0285895391447187 |
| Oat crunch | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | rs151195045 | -14.9568435902492 | 6.32176933695372 | 0.0179849992635599 |
| Oat crunch | Prepatellar bursitis (finn-b-M13_PREPATELLARBURSITIS) | All - MR Egger | -14.2386682502672 | 4.52189984484982 | 0.009261569366763 |
| Oat crunch | Shoulder lesions (finn-b-M13_SHOULDER) | rs116849846 | -3.32134130618961 | 1.61769581179475 | 0.0400598809485464 |
| Oat crunch | Shoulder lesions (finn-b-M13_SHOULDER) | rs191969679 | -4.17312204209576 | 1.56200657441573 | 0.0075481175788113 |
| Oat crunch | Shoulder lesions (finn-b-M13_SHOULDER) | All - MR Egger | -2.4837073814773 | 0.991524868561784 | 0.029248558621695 |
| Oat crunch | Sequelae of injuries of neck and trunk (finn-b-ST19_SEQUEL_INJURI_NECK_TRUNK) | All - MR Egger | -13.3269483084964 | 5.97045792145844 | 0.0473479208251007 |
| Oat crunch | Diagnoses - main ICD10: S66 Injury of muscle and tendon at wrist and hand level (ukb-a-591) | rs141655467 | -0.0291966703215556 | 0.0116617064602027 | 0.0122924361374465 |
| Oat crunch | Diagnoses - main ICD10: S66 Injury of muscle and tendon at wrist and hand level (ukb-a-591) | rs72784689 | 0.0402579728591724 | 0.0121337884661125 | 0.0009071632246043 |
| Oat crunch | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | All - Inverse variance weighted | -0.0457044303801174 | 0.0194269649999562 | 0.0186412506055435 |
| Oat crunch | Diagnoses - main ICD10: M51.1 Lumbar and other intervertebral disk disorders with radiculopathy (ukb-b-18279) | All - Inverse variance weighted | -0.024748899665449 | 0.012231235858481 | 0.0430300963189418 |
| Oat crunch | Non-cancer illness code, self-reported: joint pain (ukb-b-4122) | All - Inverse variance weighted | -0.0219114804693883 | 0.0102572677164398 | 0.0326638686827047 |
| Oat crunch | Non-cancer illness code, self-reported: other joint disorder (ukb-b-5316) | rs13220965 | -0.0605441195736176 | 0.0204128972396196 | 0.0030172613564616 |
| Oat crunch | Non-cancer illness code, self-reported: other joint disorder (ukb-b-5316) | All - Inverse variance weighted | -0.0404403569291654 | 0.0188012952388994 | 0.0314813600850945 |
| Oat crunch | Operative procedures - secondary OPCS: Z67.6 Lumbosacral joint (ukb-b-7012) | rs13220965 | 0.0293726255163619 | 0.0131397809916312 | 0.0253913043474532 |
| Oat crunch | Fractured heel (left) (ukb-b-8221) | rs12593521 | 0.0928990706882002 | 0.0400033966850477 | 0.0202178871027313 |
| Oat crunch | Fractured heel (left) (ukb-b-8221) | All - Inverse variance weighted | 0.025849640444879 | 0.0116448250426719 | 0.0264296771098854 |
| Oat crunch | Osteoarthrosis (ukb-e-740_AFR) | rs10434441 | -12.496743339854 | 5.93043332347136 | 0.0350982857051751 |
| Oat crunch | Osteoarthrosis (ukb-e-740_AFR) | All - Inverse variance weighted | -8.80515631859283 | 3.38360783889024 | 0.0092601316545393 |