ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Sushi (ukb-b-5213)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Sushi (👉 📊) Total body bone mineral density (age over 60) (ebi-a-GCST005349) MR Egger 71 1.925364351 0.816541216 0.021216493
Sushi (👉 📊) Total body bone mineral density (age 45-60) (ebi-a-GCST005350) MR Egger 69 -2.077611992 0.905661585 0.0249309
Sushi (👉 📊) Heel bone mineral density (ebi-a-GCST006979) Inverse variance weighted 71 0.124289966 0.062002472 0.045006153
Sushi (👉 📊) Rheumatoid arthritis (ebi-a-GCST90013534) Inverse variance weighted 44 0.943520422 0.349050761 0.00686953
Sushi (👉 📊) Bone mineral density (ebi-a-GCST90014022) MR Egger 63 0.554119921 0.165714108 0.001416623
Sushi (👉 📊) Bone mineral density (ebi-a-GCST90014022) Weighted median 63 0.271079723 0.100897023 0.007216239
Sushi (👉 📊) Bone mineral density (ebi-a-GCST90014022) Inverse variance weighted 63 0.277900079 0.073825645 0.000167033
Sushi (👉 📊) Juvenile rheumatoid arthritis (ebi-a-GCST90018653) Simple mode 20 -17.81523069 6.03553294 0.008190663
Sushi (👉 📊) Osteoarthritis (ebi-a-GCST90038686) Inverse variance weighted 47 0.045677361 0.021987284 0.037760559
Sushi (👉 📊) Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) MR Egger 69 -6.398948114 2.871928581 0.029234869
Sushi (👉 📊) Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) Inverse variance weighted 69 -2.461658982 1.124962557 0.028654007
Sushi (👉 📊) Drug-induced osteoporosis (finn-b-DRUGADVERS_OSTEOPO) MR Egger 69 -16.68049718 7.752680219 0.035039045
Sushi (👉 📊) Achilles tendinitis (finn-b-M13_ACHILLESTEND) Weighted median 69 2.829487167 1.436703096 0.048903655
Sushi (👉 📊) Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) Inverse variance weighted 69 8.325581161 3.603230481 0.020855622
Sushi (👉 📊) Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) Weighted median 69 -9.147219586 3.630759854 0.011756577
Sushi (👉 📊) Infective bursitis (finn-b-M13_INFBURSA) MR Egger 69 -10.10090237 4.343332058 0.023075211
Sushi (👉 📊) Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) Inverse variance weighted 69 2.869755766 1.360005161 0.034849181
Sushi (👉 📊) Collapsed vertebra, not elsewhere classified (finn-b-M13_VERTEBCOLLAPSE) Simple mode 69 -24.23954221 11.31710841 0.035790572
Sushi (👉 📊) Pain (limb, back, neck, head abdominally) (finn-b-PAIN) Inverse variance weighted 69 -0.365371774 0.168411061 0.030042953
Sushi (👉 📊) Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) Weighted median 69 1.939096442 0.980732151 0.048019853
Sushi (👉 📊) Fracture of lumbar spine and pelvis (finn-b-ST19_FRACT_LUMBAR_SPINE_PELVIS) Inverse variance weighted 69 -1.463734027 0.651127695 0.024576291
Sushi (👉 📊) Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) MR Egger 69 -20.03734764 7.827907639 0.012737581
Sushi (👉 📊) Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) Inverse variance weighted 69 -4.386690029 2.023281408 0.030150567
Sushi (👉 📊) Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) MR Egger 69 -4.055796797 1.844954923 0.031385019
Sushi (👉 📊) Bone morphogenetic protein receptor type-1A (prot-a-259) MR Egger 64 -4.235662629 1.956750083 0.034273705
Sushi (👉 📊) Fractured bone site(s): Ankle (ukb-a-438) MR Egger 70 0.049471525 0.022187328 0.029071717
Sushi (👉 📊) Heel bone mineral density (BMD) T-score automated (ukb-a-500) Weighted median 70 0.465527304 0.147522717 0.001601512
Sushi (👉 📊) Heel bone mineral density (BMD) T-score automated (ukb-a-500) Inverse variance weighted 70 0.325875404 0.108047478 0.002561003
Sushi (👉 📊) Heel bone mineral density (BMD) T-score automated (ukb-a-500) Weighted mode 70 0.708587633 0.341095255 0.041489796
Sushi (👉 📊) Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) Inverse variance weighted 70 0.008465526 0.004247658 0.046262907
Sushi (👉 📊) Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC (ukb-b-14157) Inverse variance weighted 2 0.086899215 0.036899803 0.018522463
Sushi (👉 📊) Diagnoses - main ICD10: M75.4 Impingement syndrome of shoulder (ukb-b-1418) Inverse variance weighted 2 -0.072959046 0.033195681 0.027959975
Sushi (👉 📊) Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) Inverse variance weighted 49 0.054769873 0.023121688 0.017847533
Sushi (👉 📊) Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) Inverse variance weighted 2 -0.09145462 0.044310311 0.039021703
Sushi (👉 📊) Diagnoses - main ICD10: Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device (ukb-b-19542) Inverse variance weighted 2 0.09698667 0.032212612 0.002605354
Sushi (👉 📊) Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) Inverse variance weighted 71 0.213589016 0.085421522 0.012404887
Sushi (👉 📊) Operative procedures - secondary OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-20239) Wald ratio 1 -0.08955339 0.037168158 0.015978269
Sushi (👉 📊) Heel bone mineral density (BMD) (ukb-b-8875) Inverse variance weighted 71 0.208888205 0.085402956 0.014448584
Sushi (👉 📊) Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) Weighted median 17 5.839421234 2.72907038 0.03237815
Sushi (👉 📊) Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) Inverse variance weighted 17 3.994564767 1.847139883 0.030574457
Sushi (👉 📊) Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) Simple mode 17 8.747182025 3.869882327 0.038097194
Sushi (👉 📊) Ankle spacing width (left) (ukb-e-4100_EAS) MR Egger 22 -5.033892256 2.40555376 0.04934078
Sushi (👉 📊) Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) Weighted median 22 2.794222531 1.145001644 0.014672408
Sushi (👉 📊) Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) Inverse variance weighted 22 2.470047766 1.073447906 0.021389307
Sushi (👉 📊) Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) Weighted mode 22 2.525161956 1.073270095 0.028460784
Sushi (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) Weighted median 22 3.143660206 1.128483517 0.00534059
Sushi (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) Inverse variance weighted 22 2.499610828 1.075394322 0.020105845
Sushi (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) Weighted mode 22 2.658464306 0.994226377 0.01420743
Sushi (👉 📊) Ankle spacing width (right) (ukb-e-4119_EAS) MR Egger 22 -5.635809904 2.408518228 0.029768993
Sushi (👉 📊) Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) Weighted median 22 2.760612861 1.220694219 0.02372766
Sushi (👉 📊) Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) Inverse variance weighted 22 2.404274013 0.908327005 0.008122722
Sushi (👉 📊) Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) Weighted mode 22 2.418512376 1.068824554 0.034372015
Sushi (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) Weighted median 22 2.794176291 1.163513894 0.016328098
Sushi (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) Inverse variance weighted 22 2.471603628 0.926186898 0.007617269
Sushi (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) Weighted mode 22 2.469657506 1.102414445 0.036020086
Sushi (👉 📊) Pain in joint (ukb-e-745_CSA) MR Egger 38 -15.98939108 5.83565967 0.009500624

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Sushi Total body bone mineral density (age over 60) (ebi-a-GCST005349) rs17452433 -9.49669708841403 3.04070579629034 0.0017890318568884
Sushi Total body bone mineral density (age over 60) (ebi-a-GCST005349) rs74425988 7.8313617916079 3.78155259992558 0.0383645703216527
Sushi Total body bone mineral density (age over 60) (ebi-a-GCST005349) rs7583354 4.80954617795321 2.43982809027364 0.0486936447827713
Sushi Total body bone mineral density (age over 60) (ebi-a-GCST005349) All - MR Egger 1.92536435080418 0.816541216390449 0.0212164927956165
Sushi Total body bone mineral density (age 45-60) (ebi-a-GCST005350) rs2229360 -5.31907106571737 2.61073671574201 0.0416116583250717
Sushi Total body bone mineral density (age 45-60) (ebi-a-GCST005350) All - MR Egger -2.07761199238324 0.905661585285485 0.0249308998312511
Sushi Heel bone mineral density (ebi-a-GCST006979) rs114284650 1.34039018275516 0.531880179472129 0.011732216104039
Sushi Heel bone mineral density (ebi-a-GCST006979) rs115486703 1.33672925427945 0.498162218046125 0.0072894936290001
Sushi Heel bone mineral density (ebi-a-GCST006979) rs141181868 1.03241447817719 0.439259328242379 0.0187556145885065
Sushi Heel bone mineral density (ebi-a-GCST006979) rs150569426 -1.10503467911473 0.50219744748473 0.0277786103171151
Sushi Heel bone mineral density (ebi-a-GCST006979) All - Inverse variance weighted 0.124289966050886 0.0620024720233837 0.0450061534253314
Sushi Rheumatoid arthritis (ebi-a-GCST90013534) rs148236782 15.6270817169414 6.92011692881606 0.0239325298825292
Sushi Rheumatoid arthritis (ebi-a-GCST90013534) All - Inverse variance weighted 0.943520422327898 0.34905076056063 0.0068695298984611
Sushi Bone mineral density (ebi-a-GCST90014022) rs112776808 1.31802067800962 0.582889786406233 0.0237479059014874
Sushi Bone mineral density (ebi-a-GCST90014022) rs114284650 1.51280380433161 0.593312573992459 0.0107797549048755
Sushi Bone mineral density (ebi-a-GCST90014022) rs115486703 1.75148751029815 0.552820750297502 0.0015334701695545
Sushi Bone mineral density (ebi-a-GCST90014022) All - Inverse variance weighted 0.277900078808782 0.073825645185262 0.0001670325499046
Sushi Bone mineral density (ebi-a-GCST90014022) All - MR Egger 0.554119921485551 0.165714108491216 0.0014166230695326
Sushi Osteoarthritis (ebi-a-GCST90038686) rs189242249 0.298303256178894 0.151388779913692 0.0487873987844722
Sushi Osteoarthritis (ebi-a-GCST90038686) All - Inverse variance weighted 0.0456773608621629 0.0219872840417044 0.0377605586786186
Sushi Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) rs112365162 69.8513183252048 31.2220750837075 0.0252705682357868
Sushi Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) rs147909970 -13.5828440790392 6.82630488681858 0.0466151893854224
Sushi Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) rs78998021 -19.4005099766409 8.47583554739276 0.0220839977268895
Sushi Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) All - Inverse variance weighted -2.46165898178699 1.12496255659807 0.0286540070502497
Sushi Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) All - MR Egger -6.39894811387311 2.87192858071505 0.0292348693376763
Sushi Drug-induced osteoporosis (finn-b-DRUGADVERS_OSTEOPO) rs5996535 63.6148818218219 23.5059244178505 0.0068030590431479
Sushi Drug-induced osteoporosis (finn-b-DRUGADVERS_OSTEOPO) All - MR Egger -16.6804971802212 7.75268021948943 0.0350390445494982
Sushi Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs143542640 36.889014429867 15.397467411098 0.0165848359451754
Sushi Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs145847741 -8.47946232219486 3.43049641301035 0.0134438945721788
Sushi Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs4355520 9.63080163194463 3.30728078020077 0.0035912263546737
Sushi Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs77376288 -7.93994574931135 3.18775364299682 0.0127468337177369
Sushi Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) rs141181868 88.7253988948904 30.1545911715403 0.0032573023658669
Sushi Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) rs5996535 63.7953495716711 28.175527445197 0.0235611176649612
Sushi Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) All - Inverse variance weighted 8.32558116095372 3.60323048076552 0.0208556219207659
Sushi Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs112365162 190.917606020477 77.5061098371069 0.0137680501972612
Sushi Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs115129823 33.8494521200572 14.4294902334445 0.0189836311136322
Sushi Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs115384920 112.678871462389 56.3810761123707 0.0456600003092012
Sushi Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs115486703 -55.5426922186384 26.8424935249552 0.0385266077055275
Sushi Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs117165655 227.081948409129 76.3500567004262 0.002937333571365
Sushi Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs561262254 -50.6951015357741 20.6073950069146 0.013891992506553
Sushi Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs8086196 -85.1116790016926 43.4187381766287 0.0499663146689631
Sushi Infective bursitis (finn-b-M13_INFBURSA) rs115129823 25.6729394949976 10.3918532634588 0.0134929183063473
Sushi Infective bursitis (finn-b-M13_INFBURSA) rs142749748 -56.6950695893762 28.3608278942401 0.0456015839860077
Sushi Infective bursitis (finn-b-M13_INFBURSA) rs4355520 15.1870333426819 6.52989517242839 0.0200308316604912
Sushi Infective bursitis (finn-b-M13_INFBURSA) rs72806087 -13.6495206734472 6.24053960750989 0.0287254429202256
Sushi Infective bursitis (finn-b-M13_INFBURSA) rs78153473 55.1058647594566 25.8384785383562 0.0329488941417685
Sushi Infective bursitis (finn-b-M13_INFBURSA) All - MR Egger -10.1009023654165 4.34333205754711 0.0230752107062989
Sushi Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) rs145847741 11.7081648285575 4.7895166006375 0.0145037003560739
Sushi Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) rs189242249 25.4086569896692 12.0897083823722 0.03558161631791
Sushi Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) rs78510806 66.6268442745356 27.7163849232423 0.0162221279508244
Sushi Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) All - Inverse variance weighted 2.86975576593461 1.36000516134402 0.0348491813329672
Sushi Collapsed vertebra, not elsewhere classified (finn-b-M13_VERTEBCOLLAPSE) rs145931064 136.335538516171 66.5062100228409 0.0403676472693512
Sushi Collapsed vertebra, not elsewhere classified (finn-b-M13_VERTEBCOLLAPSE) rs57321543 393.077213462264 153.259575456631 0.0103241010187353
Sushi Pain (limb, back, neck, head abdominally) (finn-b-PAIN) rs137875216 6.00527069369799 2.97565935548131 0.0435776092910186
Sushi Pain (limb, back, neck, head abdominally) (finn-b-PAIN) rs147909970 -3.16628921637025 1.00355268383261 0.0016045398433486
Sushi Pain (limb, back, neck, head abdominally) (finn-b-PAIN) rs561262254 -2.99330373389621 1.41931727199942 0.0349467949422183
Sushi Pain (limb, back, neck, head abdominally) (finn-b-PAIN) rs76437024 -6.34081787894232 2.09917861521299 0.0025225892954907
Sushi Pain (limb, back, neck, head abdominally) (finn-b-PAIN) rs77376288 -1.61490422019892 0.609794562314696 0.0080903477492877
Sushi Pain (limb, back, neck, head abdominally) (finn-b-PAIN) rs78510806 8.84654441192282 4.02604384445374 0.0279969310583065
Sushi Pain (limb, back, neck, head abdominally) (finn-b-PAIN) All - Inverse variance weighted -0.365371774490234 0.168411060841076 0.030042953057751
Sushi Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) rs113377951 11.8612313456942 5.32980166677434 0.0260507393149405
Sushi Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) rs146729456 -21.9467247445133 10.4027056458368 0.0348830723914178
Sushi Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) rs17452433 -22.3205432727689 10.0695836877151 0.0266483723175808
Sushi Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) rs57321543 53.889711647356 20.8032058541685 0.0095849914767215
Sushi Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) rs77376288 -4.9919044515003 2.36347961393696 0.0346779035254576
Sushi Fracture of lumbar spine and pelvis (finn-b-ST19_FRACT_LUMBAR_SPINE_PELVIS) rs140497463 18.3907637497612 8.47130107990209 0.0299350175676167
Sushi Fracture of lumbar spine and pelvis (finn-b-ST19_FRACT_LUMBAR_SPINE_PELVIS) rs2229360 -5.13851544238568 2.29354440448364 0.025063310276868
Sushi Fracture of lumbar spine and pelvis (finn-b-ST19_FRACT_LUMBAR_SPINE_PELVIS) rs5996535 -11.7980791463875 5.00798005831364 0.0184800871130422
Sushi Fracture of lumbar spine and pelvis (finn-b-ST19_FRACT_LUMBAR_SPINE_PELVIS) rs61905205 -22.4883901831076 9.36839628740205 0.0163748163071055
Sushi Fracture of lumbar spine and pelvis (finn-b-ST19_FRACT_LUMBAR_SPINE_PELVIS) All - Inverse variance weighted -1.46373402715839 0.651127694772441 0.0245762908548551
Sushi Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) rs115486703 69.4404807417898 32.3617625045096 0.0318923652214727
Sushi Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) rs150569426 73.4924103226234 31.6912482825975 0.0203943424572385
Sushi Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) rs77376288 -23.2941522804214 11.2496583047711 0.0383911226610965
Sushi Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) All - MR Egger -20.0373476433024 7.82790763891353 0.0127375806213775
Sushi Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) rs58559663 41.4807140580172 17.771756455212 0.019591495768782
Sushi Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) All - Inverse variance weighted -4.38669002911865 2.02328140844275 0.0301505672652885
Sushi Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) rs113377951 -11.9645971962013 5.71742360617611 0.0363799302186549
Sushi Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) rs192705709 62.0814567187282 29.2644387354753 0.0338885104394163
Sushi Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) rs61905205 19.4786339097794 9.7287192215329 0.0452655211197877
Sushi Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) rs72806087 -4.98800577139266 2.54490090377176 0.0499957902964409
Sushi Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) rs77376288 -6.45541140105558 2.52749332380091 0.0106469849430053
Sushi Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) rs78153473 32.0326343523457 10.4858209136822 0.002251713673828
Sushi Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) rs78998021 12.0718246821562 5.24836100164643 0.0214418047888217
Sushi Superficial injury of wrist and hand (finn-b-ST19_SUPERF_INJURY_WRIST_HAND) All - MR Egger -4.05579679660066 1.84495492324192 0.0313850187318155
Sushi Bone morphogenetic protein receptor type-1A (prot-a-259) rs146349685 16.6970515022964 7.4325982540406 0.0246744140133139
Sushi Bone morphogenetic protein receptor type-1A (prot-a-259) rs2229360 -16.4159220780488 6.26088823606916 0.0087420628997629
Sushi Bone morphogenetic protein receptor type-1A (prot-a-259) All - MR Egger -4.235662628534 1.95675008312549 0.0342737045554965
Sushi Fractured bone site(s): Ankle (ukb-a-438) rs115384920 -0.191132472626654 0.0885874125291743 0.0309622201261586
Sushi Fractured bone site(s): Ankle (ukb-a-438) rs138904095 0.155619935854153 0.0731752194463201 0.0334470665193225
Sushi Fractured bone site(s): Ankle (ukb-a-438) rs145847741 0.184445396216158 0.0833647692548451 0.0269314372489419
Sushi Fractured bone site(s): Ankle (ukb-a-438) rs146349685 0.17489745117975 0.0870667531465835 0.0445610809551593
Sushi Fractured bone site(s): Ankle (ukb-a-438) rs4355520 0.165412722183123 0.0789921524841647 0.0362564225779127
Sushi Fractured bone site(s): Ankle (ukb-a-438) All - MR Egger 0.0494715251561448 0.0221873280898103 0.0290717171197871
Sushi Heel bone mineral density (BMD) T-score automated (ukb-a-500) rs114284650 2.73336351064994 0.89110299750291 0.0021593441740061
Sushi Heel bone mineral density (BMD) T-score automated (ukb-a-500) rs115486703 1.66391151938744 0.831341909290141 0.0453410347335977
Sushi Heel bone mineral density (BMD) T-score automated (ukb-a-500) rs150569426 -1.90473175415073 0.854198738640314 0.0257576595293655
Sushi Heel bone mineral density (BMD) T-score automated (ukb-a-500) rs4355520 -1.77761314869005 0.865703233726856 0.0400362476367514
Sushi Heel bone mineral density (BMD) T-score automated (ukb-a-500) rs57321543 1.83747132444754 0.864988239393675 0.0336473064164736
Sushi Heel bone mineral density (BMD) T-score automated (ukb-a-500) rs8086196 2.01610467624705 0.969599415883973 0.0375882115263829
Sushi Heel bone mineral density (BMD) T-score automated (ukb-a-500) All - Inverse variance weighted 0.325875404248491 0.108047478284913 0.0025610034990019
Sushi Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) rs112365162 0.0790026161945674 0.0369000785934993 0.0322750260469132
Sushi Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) rs117337009 0.115421729730194 0.0372864271928957 0.0019645304500964
Sushi Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) rs142509655 0.0718741782391465 0.0358920722773889 0.04523007457607
Sushi Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) rs143542640 -0.0900486204181716 0.0372936036203881 0.0157530952482564
Sushi Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) rs150569426 0.0695005876413236 0.0334775537567662 0.0378906744605759
Sushi Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) All - Inverse variance weighted 0.0084655263881896 0.004247658320324 0.0462629073499496
Sushi Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC (ukb-b-14157) rs61905205 0.100093048098873 0.0493773831652886 0.0426518665752583
Sushi Operative procedures - main OPCS: W28.3 Removal of internal fixation from bone NEC (ukb-b-14157) All - Inverse variance weighted 0.0868992150410681 0.0368998027026806 0.0185224629796766
Sushi Diagnoses - main ICD10: M75.4 Impingement syndrome of shoulder (ukb-b-1418) All - Inverse variance weighted -0.0729590455743376 0.0331956813843182 0.0279599747002526
Sushi Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs4355520 0.43473650232568 0.158251004090445 0.006011881152466
Sushi Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) All - Inverse variance weighted 0.0547698731299801 0.0231216882192506 0.0178475325090699
Sushi Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) All - Inverse variance weighted -0.091454619542029 0.0443103113034855 0.0390217029289814
Sushi Diagnoses - main ICD10: Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device (ukb-b-19542) rs61905205 0.106491747545035 0.0431050087007391 0.0134917111822535
Sushi Diagnoses - main ICD10: Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device (ukb-b-19542) All - Inverse variance weighted 0.0969866697215427 0.0322126120287589 0.0026053544372927
Sushi Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) rs114284650 1.49378712058657 0.737422525542943 0.0427968840272639
Sushi Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) rs115486703 1.7699676382375 0.688465535530631 0.0101438188435328
Sushi Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) rs57321543 1.57999825768795 0.703359758399396 0.0246810464500965
Sushi Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) rs6906404 -1.91327986013128 0.799406478130176 0.0166941470533999
Sushi Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) rs8086196 1.85009624639076 0.791624904583319 0.0194346626044877
Sushi Heel bone mineral density (BMD) T-score, automated (ukb-b-20124) All - Inverse variance weighted 0.213589016138931 0.0854215215195907 0.0124048871126526
Sushi Operative procedures - secondary OPCS: W90.3 Injection of therapeutic substance into joint (ukb-b-20239) rs61905205 -0.0895533903208782 0.0371681584742655 0.0159782685917179
Sushi Heel bone mineral density (BMD) (ukb-b-8875) rs114284650 1.69043544873007 0.737641393993056 0.0219243173914099
Sushi Heel bone mineral density (BMD) (ukb-b-8875) rs115486703 1.79987938378035 0.688379381088023 0.0089315803071243
Sushi Heel bone mineral density (BMD) (ukb-b-8875) rs57321543 1.55266718936028 0.703162296367279 0.0272358636300781
Sushi Heel bone mineral density (BMD) (ukb-b-8875) rs6906404 -1.74046070793203 0.799467824059874 0.029478770482303
Sushi Heel bone mineral density (BMD) (ukb-b-8875) rs8086196 1.76447844412731 0.791362716139524 0.025769297068738
Sushi Heel bone mineral density (BMD) (ukb-b-8875) All - Inverse variance weighted 0.208888205381878 0.0854029563185265 0.0144485840755914
Sushi Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs112776808 12.6003535208903 6.40880049769421 0.0492868646672332
Sushi Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) All - Inverse variance weighted 3.99456476718213 1.84713988310678 0.030574456533786
Sushi Ankle spacing width (left) (ukb-e-4100_EAS) rs11103770 -21.3327737851685 10.2652402302788 0.0376949644149172
Sushi Ankle spacing width (left) (ukb-e-4100_EAS) rs141181868 9.61072825479605 4.21804184516049 0.022697934504378
Sushi Ankle spacing width (left) (ukb-e-4100_EAS) rs17452433 27.8290682660485 13.7757193031936 0.0433674626112317
Sushi Ankle spacing width (left) (ukb-e-4100_EAS) All - MR Egger -5.03389225584717 2.40555376009959 0.0493407799990078
Sushi Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs6906404 26.0490153978284 12.8826452364886 0.0431738921878218
Sushi Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs72806087 7.31161094440166 3.43008382682281 0.0330386821216455
Sushi Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs7583354 19.3223167149257 6.2166539300162 0.0018826005037937
Sushi Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs78849633 8.79196813267214 4.14193967970084 0.0337815746909311
Sushi Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs78998021 -11.8816236039538 4.41444814940295 0.0071124909025907
Sushi Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) All - Inverse variance weighted 2.470047766172 1.07344790648908 0.0213893072870449
Sushi Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs6906404 25.2745230353966 12.7982945831544 0.0482868495389117
Sushi Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs72806087 7.01507466517956 3.40751166228501 0.0395221309036489
Sushi Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs7583354 19.0138327035118 6.17599012851163 0.0020792718041884
Sushi Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs78849633 8.38549711405577 4.11348670839769 0.041496203513475
Sushi Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs78998021 -12.0064430615241 4.38532360930321 0.0061838638875253
Sushi Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) All - Inverse variance weighted 2.49961082779965 1.07539432163455 0.0201058448856955
Sushi Ankle spacing width (right) (ukb-e-4119_EAS) rs17452433 28.7104322649733 13.8638557030861 0.0383696693550053
Sushi Ankle spacing width (right) (ukb-e-4119_EAS) All - MR Egger -5.63580990447109 2.40851822811481 0.0297689925631074
Sushi Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs72806087 8.3162935620646 3.34820440644059 0.0129986234178639
Sushi Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs7583354 13.6363955045466 6.05189542392013 0.024243784632483
Sushi Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs77376288 3.75212902411843 1.70742477448115 0.0279821208600013
Sushi Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) All - Inverse variance weighted 2.40427401336141 0.908327005072206 0.0081227218816085
Sushi Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) rs72806087 8.1481088066849 3.36236733320941 0.0153791611804889
Sushi Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) rs7583354 13.6153625037684 6.07853722490588 0.025096913851442
Sushi Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) rs77376288 3.72521395378178 1.71457409003932 0.0298047123061258
Sushi Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) All - Inverse variance weighted 2.47160362842758 0.926186898105906 0.0076172685808439
Sushi Pain in joint (ukb-e-745_CSA) rs145931064 -46.8656153687653 15.4231276770174 0.0023763419776267
Sushi Pain in joint (ukb-e-745_CSA) rs61905205 72.9971873615671 34.9937155441194 0.0369778549517133
Sushi Pain in joint (ukb-e-745_CSA) rs7583354 -24.0547418900255 11.1825454137542 0.0314685301563252
Sushi Pain in joint (ukb-e-745_CSA) All - MR Egger -15.989391081746 5.83565966979106 0.0095006238228831