ONMR: An Orthopedic and Nutritional Mendelian Randomization Database

Coffee (ukb-b-5237)

Mendelian Randomization Results

Intake (exposure) Outcome Method Number of SNPs b se P-value
Coffee (👉 📊) Total body bone mineral density (ebi-a-GCST005348) MR Egger 116 0.325290432 0.157899033 0.041663869
Coffee (👉 📊) Rheumatoid arthritis (ebi-a-GCST005569) Inverse variance weighted 11 1.478513021 0.553591562 0.007567859
Coffee (👉 📊) Rheumatoid arthritis (ebi-a-GCST005569) Simple mode 11 3.055773156 1.356127528 0.047909835
Coffee (👉 📊) Osteoarthritis (self-reported) (ebi-a-GCST005811) MR Egger 114 0.701562886 0.282957963 0.014650187
Coffee (👉 📊) Osteoarthritis (self-reported) (ebi-a-GCST005811) Weighted median 114 0.511732155 0.217189561 0.018465237
Coffee (👉 📊) Osteoarthritis (self-reported) (ebi-a-GCST005811) Inverse variance weighted 114 0.318256889 0.132831482 0.01657759
Coffee (👉 📊) Osteoarthritis (self-reported) (ebi-a-GCST005811) Weighted mode 114 0.624196215 0.236372659 0.009443249
Coffee (👉 📊) Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) MR Egger 116 1.319836374 0.392050585 0.001038414
Coffee (👉 📊) Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) Inverse variance weighted 116 0.566706709 0.185922915 0.002303136
Coffee (👉 📊) Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) MR Egger 116 1.768189449 0.480830892 0.000361032
Coffee (👉 📊) Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) Inverse variance weighted 116 0.737546667 0.229574013 0.001315051
Coffee (👉 📊) Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) MR Egger 115 1.057794974 0.316899172 0.001143349
Coffee (👉 📊) Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) Inverse variance weighted 115 0.4133991 0.150996767 0.006185149
Coffee (👉 📊) Knee osteoarthritis (ebi-a-GCST007090) MR Egger 118 1.080173088 0.224983655 4.75e-06
Coffee (👉 📊) Knee osteoarthritis (ebi-a-GCST007090) Weighted median 118 0.603420237 0.150180317 5.87e-05
Coffee (👉 📊) Knee osteoarthritis (ebi-a-GCST007090) Inverse variance weighted 118 0.601993368 0.105874975 1.3e-08
Coffee (👉 📊) Knee osteoarthritis (ebi-a-GCST007090) Weighted mode 118 0.817986398 0.178473947 1.15e-05
Coffee (👉 📊) Osteoarthritis (hip) (ebi-a-GCST007091) MR Egger 118 0.90837998 0.320768759 0.005457195
Coffee (👉 📊) Osteoarthritis (hip) (ebi-a-GCST007091) Inverse variance weighted 118 0.450673559 0.148856733 0.00246532
Coffee (👉 📊) Osteoarthritis (hip) (ebi-a-GCST007091) Weighted mode 118 0.524803623 0.204796733 0.011659514
Coffee (👉 📊) Osteoarthritis of the hip or knee (ebi-a-GCST007092) MR Egger 118 0.957055935 0.207954354 1.08e-05
Coffee (👉 📊) Osteoarthritis of the hip or knee (ebi-a-GCST007092) Weighted median 118 0.584274297 0.130530899 7.6e-06
Coffee (👉 📊) Osteoarthritis of the hip or knee (ebi-a-GCST007092) Inverse variance weighted 118 0.516870187 0.097708594 1.22e-07
Coffee (👉 📊) Osteoarthritis of the hip or knee (ebi-a-GCST007092) Weighted mode 118 0.691302666 0.137802818 1.89e-06
Coffee (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) MR Egger 112 2.062281881 0.932158366 0.029007209
Coffee (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) Weighted median 112 1.233753683 0.61920163 0.04631721
Coffee (👉 📊) Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) Weighted mode 112 1.849904518 0.877001084 0.037162159
Coffee (👉 📊) Osteoarthritis (Firth correction) (ebi-a-GCST90013881) MR Egger 104 0.745600783 0.213836121 0.000722537
Coffee (👉 📊) Osteoarthritis (Firth correction) (ebi-a-GCST90013881) Weighted median 104 0.434545185 0.157431531 0.005776298
Coffee (👉 📊) Osteoarthritis (Firth correction) (ebi-a-GCST90013881) Inverse variance weighted 104 0.350033293 0.103057869 0.000682602
Coffee (👉 📊) Osteoarthritis (Firth correction) (ebi-a-GCST90013881) Weighted mode 104 0.723663677 0.153208426 7.36e-06
Coffee (👉 📊) Osteoarthritis (SPA correction) (ebi-a-GCST90013931) MR Egger 104 0.743632816 0.214701866 0.000780637
Coffee (👉 📊) Osteoarthritis (SPA correction) (ebi-a-GCST90013931) Weighted median 104 0.433707076 0.164104985 0.008220817
Coffee (👉 📊) Osteoarthritis (SPA correction) (ebi-a-GCST90013931) Inverse variance weighted 104 0.349132579 0.103224434 0.000718903
Coffee (👉 📊) Osteoarthritis (SPA correction) (ebi-a-GCST90013931) Weighted mode 104 0.730554011 0.159534941 1.31e-05
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017133) MR Egger 116 2.499015083 0.778631219 0.001727271
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017133) Weighted median 116 1.662953105 0.52806542 0.001637505
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017133) Inverse variance weighted 116 1.362321697 0.353430979 0.000115937
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017133) Weighted mode 116 1.52508694 0.570741733 0.008632135
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017134) MR Egger 116 3.903632017 1.24648687 0.002208599
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017134) Weighted median 116 2.158794297 0.960490656 0.024602007
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017134) Inverse variance weighted 116 1.395625865 0.572955568 0.014857414
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017134) Weighted mode 116 2.662276992 1.132787 0.020467365
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017135) MR Egger 116 2.235357954 0.876305203 0.012070106
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017135) Weighted median 116 1.381356559 0.609819573 0.023501087
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017135) Inverse variance weighted 116 1.2309833 0.396942264 0.001927611
Coffee (👉 📊) Neck circumference (ebi-a-GCST90017135) Weighted mode 116 1.601336109 0.710795604 0.026163502
Coffee (👉 📊) Neck circumference (BMI adjusted) (ebi-a-GCST90017136) MR Egger 116 1.312166432 0.50783971 0.011034863
Coffee (👉 📊) Neck circumference (BMI adjusted) (ebi-a-GCST90017136) Weighted median 116 1.213437098 0.397054525 0.002242388
Coffee (👉 📊) Neck circumference (BMI adjusted) (ebi-a-GCST90017136) Inverse variance weighted 116 0.658643621 0.226958919 0.003707424
Coffee (👉 📊) Neck circumference (BMI adjusted) (ebi-a-GCST90017136) Weighted mode 116 1.149483514 0.442013541 0.010528823
Coffee (👉 📊) Neck circumference (BMI adjusted) (ebi-a-GCST90017137) MR Egger 116 3.903632017 1.24648687 0.002208599
Coffee (👉 📊) Neck circumference (BMI adjusted) (ebi-a-GCST90017137) Weighted median 116 2.158794297 0.966061408 0.025441344
Coffee (👉 📊) Neck circumference (BMI adjusted) (ebi-a-GCST90017137) Inverse variance weighted 116 1.395625865 0.572955568 0.014857414
Coffee (👉 📊) Neck circumference (BMI adjusted) (ebi-a-GCST90017137) Weighted mode 116 2.662276992 1.103894325 0.017459956
Coffee (👉 📊) Neck circumference (BMI adjusted) (ebi-a-GCST90017138) Weighted median 116 1.119183514 0.466035817 0.016328153
Coffee (👉 📊) Neck circumference (BMI adjusted) (ebi-a-GCST90017138) Inverse variance weighted 116 0.75049683 0.294208354 0.010744438
Coffee (👉 📊) Neck circumference (BMI adjusted) (ebi-a-GCST90017138) Weighted mode 116 1.134377364 0.547935144 0.040665363
Coffee (👉 📊) Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) MR Egger 116 -0.811816448 0.296307478 0.007137871
Coffee (👉 📊) Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) Inverse variance weighted 116 -0.485626893 0.13177348 0.000228419
Coffee (👉 📊) Bone disorder (ebi-a-GCST90038652) MR Egger 116 -0.01319898 0.006387824 0.041068542
Coffee (👉 📊) Bone disorder (ebi-a-GCST90038652) Inverse variance weighted 116 -0.006416766 0.002957043 0.030007272
Coffee (👉 📊) Bone disorder (ebi-a-GCST90038652) Weighted mode 116 -0.01553244 0.007260783 0.034532047
Coffee (👉 📊) Joint disorder (ebi-a-GCST90038654) Weighted mode 116 0.033130144 0.013359945 0.0145942
Coffee (👉 📊) Osteoporosis (ebi-a-GCST90038656) Inverse variance weighted 116 -0.006627206 0.002684781 0.013570534
Coffee (👉 📊) Osteoarthritis (ebi-a-GCST90038686) Inverse variance weighted 116 0.011832123 0.005931789 0.046075905
Coffee (👉 📊) Osteoarthritis (ebi-a-GCST90038686) Weighted mode 116 0.031612828 0.011375777 0.006371471
Coffee (👉 📊) Fracture of forearm or wrist (ebi-a-GCST90038705) Weighted mode 116 0.006471438 0.00299219 0.032628819
Coffee (👉 📊) Fracture of lower leg or ankle (ebi-a-GCST90038707) MR Egger 116 -0.006653906 0.003078433 0.032751173
Coffee (👉 📊) Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) MR Egger 117 -1.996662701 0.856099166 0.021425662
Coffee (👉 📊) Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) Weighted median 117 -1.461025617 0.705889247 0.038474256
Coffee (👉 📊) Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) Weighted mode 117 -1.633561154 0.670992503 0.016434343
Coffee (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) MR Egger 117 -2.00307319 0.854088847 0.020726919
Coffee (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) Weighted median 117 -1.471712387 0.71086587 0.038423367
Coffee (👉 📊) Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) Weighted mode 117 -1.631289094 0.761245339 0.034208725
Coffee (👉 📊) Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) Weighted median 117 1.707593285 0.800302003 0.032868482
Coffee (👉 📊) Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) Weighted mode 117 1.832290553 0.821124477 0.027573698
Coffee (👉 📊) Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) Weighted mode 117 -3.215362726 1.470241435 0.030752187
Coffee (👉 📊) Pain in joint (finn-b-JOINTPAIN) MR Egger 117 0.610853845 0.274122539 0.027798598
Coffee (👉 📊) Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) Inverse variance weighted 117 0.387609412 0.145305557 0.007640719
Coffee (👉 📊) Achilles tendinitis (finn-b-M13_ACHILLESTEND) Weighted median 117 -1.032038005 0.521549673 0.047839497
Coffee (👉 📊) Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) MR Egger 117 0.847561439 0.406342983 0.039205768
Coffee (👉 📊) Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) Weighted median 117 0.703753078 0.262918487 0.007435188
Coffee (👉 📊) Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) Inverse variance weighted 117 0.667207372 0.186892324 0.000356968
Coffee (👉 📊) Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) Weighted mode 117 0.599947397 0.302507357 0.049702344
Coffee (👉 📊) Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) Simple mode 117 8.105452162 3.295839407 0.015396679
Coffee (👉 📊) Impingement syndrome of shoulder (finn-b-M13_IMPINGEMENT) MR Egger 117 1.033942302 0.420523247 0.015433955
Coffee (👉 📊) Loose body in joint (finn-b-M13_LOOSEJOINT) Inverse variance weighted 117 1.373800275 0.69205493 0.04713302
Coffee (👉 📊) Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) MR Egger 117 2.181546903 1.027911581 0.035957423
Coffee (👉 📊) Osteomalacia (finn-b-M13_OSTEOMALACIA) MR Egger 117 -6.959059285 2.790371278 0.01405458
Coffee (👉 📊) Osteonecrosis (finn-b-M13_OSTEONECROSIS) MR Egger 117 2.499062306 1.167193817 0.03437815
Coffee (👉 📊) Short Achilles tendon (acquired) (finn-b-M13_SHORTACHILLES) Weighted mode 117 -2.825741045 1.318622819 0.034206501
Coffee (👉 📊) Shoulder lesions (finn-b-M13_SHOULDER) MR Egger 117 0.583076783 0.245291353 0.01910111
Coffee (👉 📊) Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) MR Egger 117 4.868310242 2.416451907 0.04627421
Coffee (👉 📊) Transient synovitis (finn-b-M13_TRANSSYNOVITIS) Simple mode 117 -9.62714347 4.848718866 0.049447809
Coffee (👉 📊) Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) Inverse variance weighted 117 0.3013727 0.136768557 0.027557888
Coffee (👉 📊) Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) MR Egger 117 1.398842723 0.659493784 0.036062547
Coffee (👉 📊) Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) Weighted median 117 0.67634148 0.310172882 0.029218149
Coffee (👉 📊) Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) Inverse variance weighted 117 0.269018985 0.132035196 0.04160203
Coffee (👉 📊) Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) Inverse variance weighted 117 0.501976229 0.199350966 0.011800568
Coffee (👉 📊) Fracture of femur (finn-b-ST19_FRACT_FEMUR) MR Egger 117 1.06224733 0.485963041 0.030852446
Coffee (👉 📊) Fracture of femur (finn-b-ST19_FRACT_FEMUR) Weighted median 117 1.012932099 0.421751403 0.016317842
Coffee (👉 📊) Fracture of femur (finn-b-ST19_FRACT_FEMUR) Weighted mode 117 1.111850256 0.418250658 0.008961455
Coffee (👉 📊) Fracture of shoulder and upper arm (finn-b-ST19_FRACT_SHOUL_UPPER_ARM) Weighted median 117 0.572662116 0.271185719 0.034712432
Coffee (👉 📊) Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) Inverse variance weighted 117 0.229659002 0.110661911 0.037956783
Coffee (👉 📊) Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) Weighted mode 117 5.500020382 2.517396302 0.030914141
Coffee (👉 📊) Knee and hip osteoarthritis (ieu-a-1170) Weighted median 65 1.009620191 0.379950753 0.007878343
Coffee (👉 📊) Knee and hip osteoarthritis (ieu-a-1170) Inverse variance weighted 65 0.70826354 0.263070802 0.007096268
Coffee (👉 📊) Knee osteoarthritis (ieu-a-1171) Weighted median 65 1.009384019 0.448100694 0.024285452
Coffee (👉 📊) Knee osteoarthritis (ieu-a-1171) Inverse variance weighted 65 0.773700779 0.328725718 0.018590791
Coffee (👉 📊) Rheumatoid arthritis (ieu-a-831) Weighted mode 79 -1.028307008 0.508363975 0.046523191
Coffee (👉 📊) Psoriatic arthritis (ieu-b-5116) Weighted median 117 0.908473092 0.37833809 0.016340497
Coffee (👉 📊) Psoriatic arthritis (ieu-b-5116) Weighted mode 117 0.868251699 0.414774865 0.038500782
Coffee (👉 📊) Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) MR Egger 116 0.012520106 0.006264449 0.048031877
Coffee (👉 📊) Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) MR Egger 116 0.046476069 0.015714699 0.003771296
Coffee (👉 📊) Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) Weighted median 116 0.033249511 0.011771011 0.004732571
Coffee (👉 📊) Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) Inverse variance weighted 116 0.023614188 0.007271944 0.001165053
Coffee (👉 📊) Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) Weighted mode 116 0.045369676 0.011953889 0.000236865
Coffee (👉 📊) Fracture resulting from simple fall (ukb-a-332) MR Egger 116 -0.147759287 0.074163777 0.048723913
Coffee (👉 📊) Pain type(s) experienced in last month: Knee pain (ukb-a-476) MR Egger 116 0.099025834 0.025368638 0.000160964
Coffee (👉 📊) Pain type(s) experienced in last month: Knee pain (ukb-a-476) Weighted median 116 0.047827691 0.018425954 0.009440677
Coffee (👉 📊) Pain type(s) experienced in last month: Knee pain (ukb-a-476) Inverse variance weighted 116 0.032555548 0.012038346 0.006844422
Coffee (👉 📊) Pain type(s) experienced in last month: Knee pain (ukb-a-476) Weighted mode 116 0.062761714 0.018545936 0.000977189
Coffee (👉 📊) Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) MR Egger 116 0.026325565 0.006750212 0.000163037
Coffee (👉 📊) Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) Weighted median 116 0.011376199 0.004698677 0.015471514
Coffee (👉 📊) Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) Inverse variance weighted 116 0.013823484 0.003145866 1.11e-05
Coffee (👉 📊) Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) Weighted mode 116 0.01318606 0.006546895 0.04633372
Coffee (👉 📊) Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) Inverse variance weighted 116 0.004724033 0.002160165 0.028750877
Coffee (👉 📊) Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) Inverse variance weighted 116 0.00137554 0.000483112 0.0044099
Coffee (👉 📊) Non-cancer illness code self-reported: osteoporosis (ukb-a-87) Weighted median 116 -0.009016369 0.004576761 0.048834619
Coffee (👉 📊) Non-cancer illness code self-reported: osteoporosis (ukb-a-87) Inverse variance weighted 116 -0.006961639 0.003093119 0.024405455
Coffee (👉 📊) Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) Weighted median 108 0.007805111 0.00378457 0.039174338
Coffee (👉 📊) Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) Inverse variance weighted 71 0.003102091 0.001342938 0.020892087
Coffee (👉 📊) Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) Weighted mode 71 0.004260871 0.002006504 0.037245688
Coffee (👉 📊) Heel bone mineral density (BMD) (left) (ukb-b-1096) Inverse variance weighted 118 0.118552623 0.058352868 0.042189069
Coffee (👉 📊) Operation code: knee replacement/revision (ukb-b-11120) MR Egger 107 0.031343872 0.004723719 1.45e-09
Coffee (👉 📊) Operation code: knee replacement/revision (ukb-b-11120) Weighted median 107 0.017166707 0.004103779 2.88e-05
Coffee (👉 📊) Operation code: knee replacement/revision (ukb-b-11120) Inverse variance weighted 107 0.012513159 0.00212091 3.64e-09
Coffee (👉 📊) Operation code: knee replacement/revision (ukb-b-11120) Weighted mode 107 0.023071025 0.004192959 2.62e-07
Coffee (👉 📊) Heel bone mineral density (BMD), manual entry (ukb-b-11364) Inverse variance weighted 118 0.149321086 0.071121228 0.035770289
Coffee (👉 📊) Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) Weighted median 109 -0.008790534 0.004050582 0.029992414
Coffee (👉 📊) Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) Inverse variance weighted 109 -0.009555212 0.003110249 0.002125093
Coffee (👉 📊) Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) MR Egger 118 0.051156464 0.014715434 0.000716008
Coffee (👉 📊) Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) Weighted median 118 0.034874896 0.011146964 0.001756142
Coffee (👉 📊) Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) Inverse variance weighted 118 0.026446143 0.006857344 0.000114967
Coffee (👉 📊) Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) Weighted mode 118 0.060075492 0.011120129 3.51e-07
Coffee (👉 📊) Diagnoses - main ICD10: T84.0 Mechanical complication of internal joint prosthesis (ukb-b-14753) MR Egger 59 0.009956974 0.003295621 0.003764831
Coffee (👉 📊) Diagnoses - main ICD10: T84.0 Mechanical complication of internal joint prosthesis (ukb-b-14753) Weighted median 59 0.005801656 0.002274573 0.010752021
Coffee (👉 📊) Diagnoses - main ICD10: T84.0 Mechanical complication of internal joint prosthesis (ukb-b-14753) Weighted mode 59 0.005625557 0.002636758 0.037124012
Coffee (👉 📊) Fracture resulting from simple fall (ukb-b-15251) MR Egger 117 -0.173969779 0.062510236 0.006296591
Coffee (👉 📊) Fracture resulting from simple fall (ukb-b-15251) Weighted median 117 -0.111180137 0.049082115 0.023501246
Coffee (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) Inverse variance weighted 118 0.121303251 0.058236495 0.037256494
Coffee (👉 📊) Neck/shoulder pain for 3+ months (ukb-b-16118) Weighted mode 118 0.072008166 0.03455384 0.039342334
Coffee (👉 📊) Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) MR Egger 106 0.029438178 0.004753529 1.2e-08
Coffee (👉 📊) Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) Weighted median 106 0.01020853 0.003869088 0.008327733
Coffee (👉 📊) Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) Inverse variance weighted 106 0.009783323 0.002334592 2.78e-05
Coffee (👉 📊) Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) Weighted mode 106 0.016375185 0.004584192 0.000536158
Coffee (👉 📊) Pain type(s) experienced in last month: Knee pain (ukb-b-16254) MR Egger 118 0.101692069 0.022297636 1.27e-05
Coffee (👉 📊) Pain type(s) experienced in last month: Knee pain (ukb-b-16254) Weighted median 118 0.049352473 0.016451304 0.002700572
Coffee (👉 📊) Pain type(s) experienced in last month: Knee pain (ukb-b-16254) Inverse variance weighted 118 0.031209767 0.010779102 0.003786808
Coffee (👉 📊) Pain type(s) experienced in last month: Knee pain (ukb-b-16254) Weighted mode 118 0.058441141 0.014037664 6.03e-05
Coffee (👉 📊) Operative procedures - secondary OPCS: Z84.3 Hip joint (ukb-b-17133) MR Egger 95 0.008005222 0.003307096 0.017436361
Coffee (👉 📊) Fractured heel (ukb-b-18389) Inverse variance weighted 118 -0.002963474 0.001379709 0.031721867
Coffee (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) Inverse variance weighted 118 0.119642976 0.059382929 0.043928696
Coffee (👉 📊) Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) MR Egger 107 0.018222675 0.005133857 0.000578895
Coffee (👉 📊) Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) Weighted median 107 0.011348835 0.003402154 0.000850608
Coffee (👉 📊) Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) Inverse variance weighted 107 0.008954607 0.002338342 0.000128421
Coffee (👉 📊) Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) Weighted mode 107 0.012336976 0.004563037 0.007989799
Coffee (👉 📊) Ankle spacing width (left) (ukb-b-2122) Weighted median 118 0.185968217 0.053872568 0.000556443
Coffee (👉 📊) Ankle spacing width (left) (ukb-b-2122) Inverse variance weighted 118 0.352038315 0.06527288 6.92e-08
Coffee (👉 📊) Ankle spacing width (ukb-b-4080) Weighted median 117 0.152918192 0.040908021 0.000185418
Coffee (👉 📊) Ankle spacing width (ukb-b-4080) Inverse variance weighted 117 0.332733223 0.066410818 5.44e-07
Coffee (👉 📊) Non-cancer illness code, self-reported: joint pain (ukb-b-4122) Inverse variance weighted 78 -0.002716156 0.001244091 0.0290177
Coffee (👉 📊) Heel bone mineral density (BMD) (right) (ukb-b-4657) Inverse variance weighted 118 0.117961839 0.059706667 0.048189948
Coffee (👉 📊) Operative procedures - main OPCS: W85.2 Endoscopic irrigation of knee joint (ukb-b-4944) MR Egger 86 0.007572044 0.003016678 0.013989452
Coffee (👉 📊) Operative procedures - main OPCS: W85.2 Endoscopic irrigation of knee joint (ukb-b-4944) Weighted median 86 0.004579097 0.002143815 0.032682935
Coffee (👉 📊) Operative procedures - main OPCS: W85.2 Endoscopic irrigation of knee joint (ukb-b-4944) Inverse variance weighted 86 0.003939562 0.00142947 0.005852005
Coffee (👉 📊) Operative procedures - main OPCS: W85.2 Endoscopic irrigation of knee joint (ukb-b-4944) Weighted mode 86 0.005514595 0.002235812 0.015653014
Coffee (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) MR Egger 87 0.007056242 0.003092966 0.02502576
Coffee (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) Weighted median 87 0.006505232 0.002483536 0.008809942
Coffee (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) Inverse variance weighted 87 0.003589623 0.001459673 0.013924852
Coffee (👉 📊) Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) Weighted mode 87 0.006720113 0.002169434 0.00263481
Coffee (👉 📊) Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint (ukb-b-6725) MR Egger 69 0.005271333 0.002574541 0.044534302
Coffee (👉 📊) Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) Simple mode 88 -0.012165818 0.005414271 0.027171142
Coffee (👉 📊) Ankle spacing width (right) (ukb-b-8607) Weighted median 118 0.205222856 0.056051139 0.000250889
Coffee (👉 📊) Ankle spacing width (right) (ukb-b-8607) Inverse variance weighted 118 0.347297033 0.064167556 6.22e-08
Coffee (👉 📊) Ankle spacing width (right) (ukb-b-8607) Weighted mode 118 0.122891166 0.056800838 0.032532641
Coffee (👉 📊) Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) MR Egger 106 0.013747109 0.00592563 0.022297471
Coffee (👉 📊) Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) Weighted mode 106 0.009256114 0.004123546 0.026884444
Coffee (👉 📊) Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) MR Egger 116 0.042667217 0.01031985 6.83e-05
Coffee (👉 📊) Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) Weighted median 116 0.018998068 0.006220887 0.002258751
Coffee (👉 📊) Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) Inverse variance weighted 116 0.021962079 0.00482485 5.32e-06
Coffee (👉 📊) Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) Weighted mode 116 0.021079171 0.00723459 0.00429335
Coffee (👉 📊) Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) Weighted mode 116 -0.004767494 0.002154048 0.028852832
Coffee (👉 📊) Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) Inverse variance weighted 116 0.00712669 0.002979348 0.01675548
Coffee (👉 📊) Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) Inverse variance weighted 106 2.077934875 0.779617564 0.007691375
Coffee (👉 📊) Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) MR Egger 107 -2.768168693 0.960171834 0.004778774
Coffee (👉 📊) Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) Weighted mode 107 -2.160724876 0.867453169 0.014293998
Coffee (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) MR Egger 107 -2.683529462 0.940520593 0.005213716
Coffee (👉 📊) Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) Weighted mode 107 -2.037701761 0.852302929 0.018574487
Coffee (👉 📊) Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) MR Egger 107 -2.598297785 0.990987863 0.01004241
Coffee (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) MR Egger 107 -2.501308454 0.983893388 0.012473369
Coffee (👉 📊) Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) Weighted mode 107 -1.491050275 0.741289594 0.046818112

Mendelian Randomization Results (Single SNP)

Intake (exposure) Outcome SNP b se P-value
Coffee Total body bone mineral density (ebi-a-GCST005348) rs10193706 -1.52159001247949 0.7239823446475 0.0355800092887733
Coffee Total body bone mineral density (ebi-a-GCST005348) rs11032480 -1.95116781006706 0.734698990210437 0.0079135139423772
Coffee Total body bone mineral density (ebi-a-GCST005348) rs11206378 -1.80083972022759 0.74300380065334 0.0153620722863948
Coffee Total body bone mineral density (ebi-a-GCST005348) rs11236225 -2.49007401597961 0.715651193568943 0.0005024402646056
Coffee Total body bone mineral density (ebi-a-GCST005348) rs11678584 -1.96848824884242 0.685384572471449 0.0040776291788073
Coffee Total body bone mineral density (ebi-a-GCST005348) rs13387939 1.11139298614383 0.465093803984102 0.0168662543849259
Coffee Total body bone mineral density (ebi-a-GCST005348) rs13437947 -1.71055160484336 0.749567557178551 0.0224863127806952
Coffee Total body bone mineral density (ebi-a-GCST005348) rs1421085 -0.668730383009934 0.318186230625694 0.0355800092887733
Coffee Total body bone mineral density (ebi-a-GCST005348) rs144620429 -1.62346243005897 0.785302756865736 0.0387051698856974
Coffee Total body bone mineral density (ebi-a-GCST005348) rs2595223 -1.72758518625905 0.724860917311491 0.0171566513368353
Coffee Total body bone mineral density (ebi-a-GCST005348) rs35303290 -1.66351813576587 0.729213429376819 0.0225336575784201
Coffee Total body bone mineral density (ebi-a-GCST005348) rs476828 1.23370671217161 0.380488985996852 0.00118517452977
Coffee Total body bone mineral density (ebi-a-GCST005348) rs56113850 1.5710484972408 0.513156544324883 0.0022020269974846
Coffee Total body bone mineral density (ebi-a-GCST005348) rs62121718 -1.90156714183072 0.945090256119459 0.0442148570611558
Coffee Total body bone mineral density (ebi-a-GCST005348) rs630194 1.20669761214801 0.528480706050223 0.0224107409587429
Coffee Total body bone mineral density (ebi-a-GCST005348) rs780093 2.27178696355362 0.436303456576522 1.92025072596625e-07
Coffee Total body bone mineral density (ebi-a-GCST005348) All - MR Egger 0.325290431789264 0.157899033367585 0.0416638687206528
Coffee Rheumatoid arthritis (ebi-a-GCST005569) rs329122 4.38554046374046 2.16008609257919 0.0423299262474726
Coffee Rheumatoid arthritis (ebi-a-GCST005569) All - Inverse variance weighted 1.47851302062152 0.553591562176395 0.0075678587499099
Coffee Osteoarthritis (self-reported) (ebi-a-GCST005811) rs11206378 -4.11046073791611 1.84575996695522 0.0259489651074131
Coffee Osteoarthritis (self-reported) (ebi-a-GCST005811) rs11236225 -4.14317925591883 1.75355129650507 0.0181405737370008
Coffee Osteoarthritis (self-reported) (ebi-a-GCST005811) rs13387939 3.2333925270902 1.14584616871429 0.004774925631116
Coffee Osteoarthritis (self-reported) (ebi-a-GCST005811) rs2472297 0.795708272721795 0.339217314959071 0.0189904528214186
Coffee Osteoarthritis (self-reported) (ebi-a-GCST005811) rs6937318 4.2482925635317 1.65460125298301 0.0102416247411161
Coffee Osteoarthritis (self-reported) (ebi-a-GCST005811) rs7743687 -4.0038809448453 1.78286386228691 0.0247195070022
Coffee Osteoarthritis (self-reported) (ebi-a-GCST005811) All - Inverse variance weighted 0.318256889334342 0.132831482143539 0.0165775899320317
Coffee Osteoarthritis (self-reported) (ebi-a-GCST005811) All - MR Egger 0.701562885594583 0.282957962543037 0.0146501870674948
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) rs116814395 4.25239245021547 2.04933025534788 0.0379850799071865
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) rs12930957 -5.36757813968321 2.46462691688826 0.0294174958332224
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) rs13387939 4.8472317858394 1.61043863781877 0.0026134839225823
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) rs13437947 -6.14384009225447 2.66840284451278 0.0213103155176877
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) rs1421085 3.10122636523465 1.07044319566835 0.0037657878616522
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) rs2472297 0.947046317257288 0.470900006025289 0.0443105637319164
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) rs35303290 4.71945792096694 2.36928279580429 0.0463781625853731
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) rs476828 3.28130819031367 1.31180495903978 0.0123714220316171
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) rs516636 5.89079106254336 2.02397937773515 0.0036085148954756
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) rs56791931 5.1918766282587 2.49299739478608 0.0372891536917183
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) rs780093 3.94705683228646 1.51085116786399 0.008988997515563
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) All - Inverse variance weighted 0.566706708903456 0.185922915093442 0.002303135943963
Coffee Osteoarthritis of the hip or knee (hospital diagnosed) (ebi-a-GCST005812) All - MR Egger 1.31983637351876 0.392050585397789 0.0010384143073714
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs12930957 -5.88454836796979 3.00176183356796 0.0499531619091195
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs13387939 6.05038717549137 1.95583420915933 0.0019780576433774
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs13437947 -6.45132615798578 3.23800691908514 0.046329856368706
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs1421085 4.20403826863547 1.29756884147854 0.0011955709088763
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs2126069 -5.35247007479039 2.72746102026403 0.0497116434254603
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs2472297 1.76004071373852 0.567864121125524 0.0019390996331414
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs2595223 -6.31926499102985 3.00253097270295 0.0353221287861021
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs35303290 6.26840979060181 2.8803132883196 0.0295332511377526
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs476828 3.19125336530978 1.58791889819614 0.0444620992736353
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs516636 7.46021564311835 2.44299331146642 0.002260235123843
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs56113850 3.82886623982569 1.90122131257549 0.0440202192274703
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) rs780093 3.9126640839508 1.8344980629631 0.0329390509475982
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) All - Inverse variance weighted 0.737546666564746 0.229574012631923 0.0013150505484362
Coffee Osteoarthritis of the knee (hospital diagnosed) (ebi-a-GCST005813) All - MR Egger 1.7681894485768 0.480830892137922 0.0003610318218551
Coffee Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) rs13387939 3.797974123872 1.29096751591587 0.0032614259771891
Coffee Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) rs13437947 -5.24404189890448 2.14285027868537 0.0143959982093222
Coffee Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) rs1421085 2.16280888332812 0.866173028593617 0.0125259220389852
Coffee Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) rs2472297 0.820207528168226 0.38091016294103 0.031296413124922
Coffee Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) rs516636 3.67806828984216 1.64341808901488 0.0252171426141009
Coffee Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) rs56791931 4.82926232231217 2.00050705505919 0.0157776334875148
Coffee Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) rs6989976 -4.25689030522761 2.12781737859692 0.0454365852508748
Coffee Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) rs780093 2.49564824914432 1.22280813931621 0.0412592135393997
Coffee Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) All - Inverse variance weighted 0.413399100070439 0.150996766517728 0.0061851487954708
Coffee Osteoarthritis (hospital diagnosed) (ebi-a-GCST005814) All - MR Egger 1.05779497397994 0.316899172496589 0.0011433489270308
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs1057868 1.2981870492058 0.516267436556747 0.0119179971026641
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs11206378 -2.94682863309969 1.22154862141312 0.0158491390797818
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs1182580 2.41017370916901 1.17354007828648 0.0399985929678488
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs1421085 2.3243773796555 0.512333761176965 5.71028259144208e-06
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs2472297 1.19860213295231 0.225948337450614 1.12820154507137e-07
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs2521501 2.32168889368825 1.07985529938988 0.031555214782181
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs2595223 -2.40412204241644 1.15977746769839 0.0381800356619216
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs329122 2.44218079898113 1.07273362198237 0.0228103772300798
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs4410790 0.578419328419328 0.245700245700246 0.0185642853591186
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs476828 1.7006704677132 0.628383325358438 0.0068012553825453
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs4840338 3.39415070293257 1.22823352285109 0.0057195456090656
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs516636 2.50927059871368 0.976303236359588 0.0101647023960557
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs56212739 -3.05289624514047 1.18667395575228 0.0100923336387036
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs56791931 3.59309705733219 1.17147203329079 0.0021610012855481
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs6030315 3.06995366691777 1.2254016737697 0.0122360316334738
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs6937318 2.50643671776817 1.09435969367342 0.0220026237732584
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs75347775 2.38268391640511 1.0334532649468 0.0211354791156063
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs780093 1.76025877308459 0.714634971978787 0.0137719252285993
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs78308709 -3.19082932017609 1.12269920524714 0.0044816691604716
Coffee Knee osteoarthritis (ebi-a-GCST007090) rs9398171 2.24725310148558 0.93942547685053 0.0167496820173491
Coffee Knee osteoarthritis (ebi-a-GCST007090) All - Inverse variance weighted 0.601993367500101 0.105874975131273 1.30133823574425e-08
Coffee Knee osteoarthritis (ebi-a-GCST007090) All - MR Egger 1.08017308807844 0.224983655094496 4.7493871254205e-06
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs1057868 1.86457753785543 0.646587371998256 0.0039300686212213
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs117968677 -2.90687369279308 1.27941114860183 0.0230840762270425
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs13054099 -2.84847416424655 1.2340295239244 0.0209840863190569
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs13088645 -3.54780571441841 1.53523229096651 0.02083703272373
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs1421085 3.07939555402155 0.641765448211146 1.60002544216258e-06
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs2126069 -2.68240343347639 1.32422447981746 0.0428015841804445
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs2189234 -2.98391190851206 1.20157526517264 0.0130159226947053
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs2231142 3.11888356698439 1.46396575593145 0.0331357347404201
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs2521501 5.41007504994331 1.36061767723125 7.00280424853096e-05
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs4410790 0.813882063882064 0.309684684684685 0.0085863479013747
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs476828 2.92284721061218 0.789802895175284 0.0002149801864576
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs4840338 7.55429650613787 1.54519701261911 1.01406708444534e-06
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs516636 3.04024253427766 1.2246610771879 0.0130457666111382
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs62064918 3.01722047053117 1.31942760126122 0.0222095605970508
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs6969878 -2.63940832486173 1.3243674280225 0.0462660741069086
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs73075167 2.58965755513916 1.09562435025118 0.0180965654136911
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs73123665 3.45424199257797 1.52842566043273 0.0238212508370941
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs76852278 -3.28585064982745 1.4501798957339 0.0234622357547128
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs780093 2.32444427727837 0.902696806710046 0.0100240086635227
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) rs9398171 2.72617589360546 1.18809692660508 0.0217575701709553
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) All - Inverse variance weighted 0.450673558883192 0.148856732660173 0.0024653200236811
Coffee Osteoarthritis (hip) (ebi-a-GCST007091) All - MR Egger 0.908379980337498 0.320768758620432 0.0054571948745314
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs1057868 1.4786300367402 0.42103363758026 0.0004449074025931
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs117968677 -1.9207280719564 0.828233413578516 0.0203914499453169
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs13387939 1.72749127194095 0.610058106524602 0.0046303704439542
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs1421085 2.48616698844822 0.41525999590133 2.13729723239881e-09
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs2126069 -2.13913185201282 0.860180003983992 0.0128882586460422
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs2231142 2.15616695574686 0.954760275607466 0.0239248856195216
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs2472297 0.817717792678413 0.185062447816693 9.93401756138994e-06
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs2521501 3.35834998110253 0.885481345499703 0.0001490283940105
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs329122 1.89440192818163 0.878728605240874 0.0310958362663411
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs4410790 0.580978705978706 0.202190827190827 0.0040605683103052
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs476828 1.94279982243847 0.513083632632119 0.0001527737384271
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs4840338 4.71483191029933 1.0169245296724 3.54591935177978e-06
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs516636 2.45788621785265 0.79645790334598 0.0020285415003648
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs56791931 2.89371076880038 0.952913818124596 0.0023918555901812
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs62064918 1.91122968712103 0.853747271404317 0.0251795861857696
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs6937318 1.83570013132316 0.894315448593336 0.0401083224493613
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs780093 1.68503403919209 0.58675292436153 0.0040814780475456
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs78308709 -3.00174313823973 0.915886193754247 0.0010476065171862
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) rs9398171 2.37619385321016 0.773644510347495 0.0021303712868554
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) All - Inverse variance weighted 0.516870186658752 0.0977085944355311 1.22373030172763e-07
Coffee Osteoarthritis of the hip or knee (ebi-a-GCST007092) All - MR Egger 0.957055934679937 0.207954354258941 1.07592236201439e-05
Coffee Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) rs10992783 11.8813839933461 5.38120951174012 0.0272485043953995
Coffee Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) rs17144566 8.61032872481247 4.19519414619797 0.0401282061831036
Coffee Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) rs2350804 -9.53423440360607 4.6354761169377 0.0397057353505911
Coffee Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) rs2595223 -10.3532126439906 4.97881593969157 0.0375757536930023
Coffee Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) rs4410790 2.37490018427518 1.03411138411138 0.0216438084839863
Coffee Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) rs57918684 13.3737118202136 4.388580208592 0.0023083863012109
Coffee Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) rs73075167 10.6058304645821 4.17962014205766 0.0111643983261585
Coffee Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) rs9296406 13.1555468455877 5.39775042160255 0.0148003564422564
Coffee Osteoclast-associated immunoglobulin-like receptor levels (ebi-a-GCST90010135) All - MR Egger 2.06228188089379 0.932158365687787 0.0290072089198521
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs13054099 -2.29537842025664 0.851086966606976 0.0069968042744156
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs13387939 2.06739632032279 0.65385544642965 0.0015676743316494
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs1421085 0.939760335659508 0.444376732497061 0.0344484510023257
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs2231142 3.10698884521745 1.0247998981589 0.0024309981337218
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs2350804 2.46737928657437 1.02981969642034 0.0165781075333476
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs2472297 1.01220981777805 0.194985238041953 2.08928933450344e-07
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs329122 2.90755318590474 0.939250182022354 0.0019640785068957
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs35303290 2.39883872761372 0.980254267607656 0.0143987028699694
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs476828 1.33462853321496 0.545213045007235 0.0143690417941794
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs4840338 2.48746343363907 1.07782774355012 0.0210075492062136
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs56791931 2.49108282482122 1.02957529767629 0.0155408068498213
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs6937318 2.45402512555718 0.950602015504606 0.009835819438956
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs76852278 -2.00950143182319 1.02416476980689 0.0497522367282826
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs7743687 -2.86638715329021 1.02180749612676 0.0050283418216926
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs7989746 -2.65215124136683 1.08114112100799 0.0141629518239409
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs8056750 1.81361966335336 0.823792163899253 0.0276971089821001
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) rs9296406 2.11632878294817 1.04817743923508 0.043481415712284
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) All - Inverse variance weighted 0.350033292879152 0.103057868584617 0.0006826023128912
Coffee Osteoarthritis (Firth correction) (ebi-a-GCST90013881) All - MR Egger 0.745600782566599 0.213836120519546 0.0007225371855988
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs13054099 -2.3005001067018 0.855063696335953 0.0071357231367733
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs13387939 2.05787699778929 0.648310561857476 0.0015024244612672
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs1421085 0.940553104742593 0.445008251270048 0.0345525838307218
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs2231142 3.08677179638146 1.01306430310456 0.0023116438007044
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs2350804 2.47304175003693 1.0339009225563 0.016759017620248
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs2472297 1.01674815152741 0.196685875861832 2.34845576651611e-07
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs329122 2.9053050101225 0.937898994141048 0.0019504608133396
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs35303290 2.39572817657903 0.977780638927692 0.0142789029766561
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs476828 1.33776468485711 0.547824006549023 0.014607737440643
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs4840338 2.48746343363907 1.07759530365763 0.020979867638904
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs56791931 2.48144003636809 1.02177714055916 0.0151592053353832
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs6937318 2.45454288713268 0.950782055325178 0.00983423167503
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs76852278 -1.99020118951465 1.00407151773258 0.0474645910262029
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs7743687 -2.86181157384523 1.01880966182201 0.0049699399128002
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs7989746 -2.65340165373687 1.08182086645596 0.0141781388274039
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs8056750 1.81577473346435 0.825482042664692 0.0278314651428672
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) rs9296406 2.11616117337019 1.0477661511168 0.0434157159153557
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) All - Inverse variance weighted 0.349132579185133 0.103224434243013 0.0007189028076889
Coffee Osteoarthritis (SPA correction) (ebi-a-GCST90013931) All - MR Egger 0.743632815812174 0.214701865974484 0.0007806373760131
Coffee Neck circumference (ebi-a-GCST90017133) rs116814395 -11.1712488819913 5.43361061127236 0.039787031731495
Coffee Neck circumference (ebi-a-GCST90017133) rs13387939 7.35693835393035 2.68787977627176 0.0061987470769763
Coffee Neck circumference (ebi-a-GCST90017133) rs1421085 10.9261915804688 1.82282959239805 2.04637043985749e-09
Coffee Neck circumference (ebi-a-GCST90017133) rs17144566 7.28967495219885 3.65862626856891 0.0463203563985582
Coffee Neck circumference (ebi-a-GCST90017133) rs2465037 9.19890516098084 3.3202592247712 0.0055963727793125
Coffee Neck circumference (ebi-a-GCST90017133) rs4984636 -13.4167390958391 5.59438847335627 0.0164736421003468
Coffee Neck circumference (ebi-a-GCST90017133) rs6062682 -6.56676695209442 3.26891923165934 0.044553090774947
Coffee Neck circumference (ebi-a-GCST90017133) rs730632 9.65107646622123 4.08314773570898 0.0180965654136911
Coffee Neck circumference (ebi-a-GCST90017133) rs75347775 9.033147056572 3.95200183725025 0.0222709789592328
Coffee Neck circumference (ebi-a-GCST90017133) All - Inverse variance weighted 1.36232169723249 0.35343097879141 0.0001159368983311
Coffee Neck circumference (ebi-a-GCST90017133) All - MR Egger 2.49901508313151 0.778631219440649 0.0017272712828336
Coffee Neck circumference (ebi-a-GCST90017134) rs12514566 12.3188151475801 5.43993261502825 0.0235423888837264
Coffee Neck circumference (ebi-a-GCST90017134) rs17842490 7.1798141617019 3.14601169404206 0.0224777925856407
Coffee Neck circumference (ebi-a-GCST90017134) rs2472297 3.32682028284428 1.67847336391885 0.047473501351992
Coffee Neck circumference (ebi-a-GCST90017134) rs73075167 -13.0790156811235 6.23758863040731 0.0360107179544502
Coffee Neck circumference (ebi-a-GCST90017134) rs73228435 -21.0436222567471 8.27976295689872 0.0110354888252174
Coffee Neck circumference (ebi-a-GCST90017134) rs7590617 -16.6200256636672 7.86983558712975 0.0346980810555838
Coffee Neck circumference (ebi-a-GCST90017134) All - Inverse variance weighted 1.39562586476417 0.572955567942057 0.0148574141852441
Coffee Neck circumference (ebi-a-GCST90017134) All - MR Egger 3.90363201666726 1.24648687001656 0.0022085992906015
Coffee Neck circumference (ebi-a-GCST90017135) rs1421085 10.4516087280101 2.21651764046035 2.41321124518972e-06
Coffee Neck circumference (ebi-a-GCST90017135) rs2465037 9.49048599941684 4.07272590460604 0.0197927282397251
Coffee Neck circumference (ebi-a-GCST90017135) rs4984636 -12.8536277834225 6.46353854252103 0.0467413546412456
Coffee Neck circumference (ebi-a-GCST90017135) rs57918684 8.79997516761857 4.4543084181773 0.0481989928236466
Coffee Neck circumference (ebi-a-GCST90017135) All - Inverse variance weighted 1.23098330004457 0.396942264428384 0.0019276110498314
Coffee Neck circumference (ebi-a-GCST90017135) All - MR Egger 2.23535795427146 0.876305202550609 0.0120701062911639
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) rs10500356 -9.18789434556903 3.04992343421379 0.0025910543609847
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) rs10992783 -8.05501549344185 3.21413484673168 0.0122063339713444
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) rs12649199 7.62371971228745 3.25547037403579 0.0191900609081778
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) rs13378240 6.65283919696317 3.0501771404762 0.0291736490107418
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) rs17144566 5.21216355346374 2.63825562582733 0.0481989928236466
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) rs4840338 6.6034060368338 3.3017030184169 0.0455002638963584
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) rs4970968 6.92689929190304 3.15656170263936 0.0282034737356933
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) rs4984636 -11.3356755499516 4.3947165469035 0.0098975781059966
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) rs56113850 4.00262104573409 1.99736316483378 0.0450751414856847
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) rs730632 6.11044486322883 2.96004416271677 0.0389884584002332
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) All - Inverse variance weighted 0.658643621496685 0.22695891897136 0.0037074244827826
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017136) All - MR Egger 1.31216643224099 0.507839709917847 0.0110348627436958
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017137) rs12514566 12.3188151475801 5.43993261502825 0.0235423888837264
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017137) rs17842490 7.1798141617019 3.14601169404206 0.0224777925856407
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017137) rs2472297 3.32682028284428 1.67847336391885 0.047473501351992
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017137) rs73075167 -13.0790156811235 6.23758863040731 0.0360107179544502
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017137) rs73228435 -21.0436222567471 8.27976295689872 0.0110354888252174
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017137) rs7590617 -16.6200256636672 7.86983558712975 0.0346980810555838
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017137) All - Inverse variance weighted 1.39562586476417 0.572955567942057 0.0148574141852441
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017137) All - MR Egger 3.90363201666726 1.24648687001656 0.0022085992906015
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017138) rs12649199 8.70098445424111 4.17884015285321 0.0373284990727365
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017138) rs17144566 8.88917487865863 3.4471981173702 0.0099182441495943
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017138) rs28490963 -10.8728660267498 3.81573561837363 0.0043790625487058
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017138) rs57918684 7.4729947851999 3.422212565185 0.0289862506308143
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017138) rs730632 9.68914777378029 3.85471989035463 0.011951258491594
Coffee Neck circumference (BMI adjusted) (ebi-a-GCST90017138) All - Inverse variance weighted 0.750496829722563 0.294208354332368 0.0107444375753714
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) rs10992783 3.51586995479221 1.61362688223672 0.0293419371476866
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) rs11206378 3.42537345385946 1.58675387936137 0.0308711076071626
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) rs13387939 -3.87175491368584 1.06307155196366 0.0002704802977162
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) rs1421085 -2.66952854507998 0.717267265647752 0.0001978041379517
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) rs1527961 -3.5299143377476 1.5663526466863 0.0242220664148456
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) rs2472297 -0.852148015528031 0.389491895986297 0.0286808725922352
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) rs62121718 -6.00075379487898 1.79908747550451 0.0008516359928664
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) rs6691876 -2.97954916037833 1.39700473453636 0.0329401104302035
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) rs7224815 -3.99624316310934 1.37198209977717 0.0035825937165183
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) rs73123665 -4.4691166311053 2.0970000061137 0.0330730531563771
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) All - Inverse variance weighted -0.485626893392413 0.131773480091868 0.0002284191995724
Coffee Medication use (drugs affecting bone structure and mineralization) (ebi-a-GCST90018993) All - MR Egger -0.811816447820676 0.296307478037333 0.0071378707262003
Coffee Bone disorder (ebi-a-GCST90038652) rs11206378 0.0975193747685984 0.0392172517926541 0.0128954083806902
Coffee Bone disorder (ebi-a-GCST90038652) rs13378240 0.0839313215208989 0.0374469672031142 0.0250041703512643
Coffee Bone disorder (ebi-a-GCST90038652) rs13387939 -0.079474866814047 0.0238700636634895 0.0008700874151738
Coffee Bone disorder (ebi-a-GCST90038652) rs1527961 -0.0640625491827237 0.0323321417062002 0.0475476689570357
Coffee Bone disorder (ebi-a-GCST90038652) rs2472297 -0.0176071640686194 0.0074075548516487 0.0174578816866364
Coffee Bone disorder (ebi-a-GCST90038652) rs56349356 -0.103896972676101 0.0408232280859965 0.0109263501934322
Coffee Bone disorder (ebi-a-GCST90038652) rs62121718 -0.0845539230924264 0.0389235991314279 0.0298326766102303
Coffee Bone disorder (ebi-a-GCST90038652) rs6969878 -0.0824950336221449 0.0336905083892148 0.0143407240222762
Coffee Bone disorder (ebi-a-GCST90038652) rs73123665 -0.0966790367250118 0.0396055439055555 0.0146447050587809
Coffee Bone disorder (ebi-a-GCST90038652) rs780093 -0.0604785797570241 0.0231010644299846 0.008844688277024
Coffee Bone disorder (ebi-a-GCST90038652) All - Inverse variance weighted -0.0064167656126487 0.0029570425058641 0.0300072718636561
Coffee Bone disorder (ebi-a-GCST90038652) All - MR Egger -0.0131989799532578 0.0063878238944902 0.04106854239951
Coffee Joint disorder (ebi-a-GCST90038654) rs1057868 0.0925802845986898 0.0366019076833627 0.0114262893704647
Coffee Joint disorder (ebi-a-GCST90038654) rs11206378 -0.174094605792407 0.0871074987973413 0.0456497127922748
Coffee Joint disorder (ebi-a-GCST90038654) rs13054099 -0.207700158660939 0.0701374133627768 0.0030631166549206
Coffee Joint disorder (ebi-a-GCST90038654) rs1421085 -0.085944258086784 0.0365937355063475 0.0188438467422635
Coffee Joint disorder (ebi-a-GCST90038654) rs2231142 -0.681352736183823 0.0831039256559999 2.42791912568093e-16
Coffee Joint disorder (ebi-a-GCST90038654) rs2472297 0.0525299758127684 0.0164565705776531 0.0014127342375921
Coffee Joint disorder (ebi-a-GCST90038654) rs34060476 -0.175322857204871 0.0528584528899789 0.0009104280844326
Coffee Joint disorder (ebi-a-GCST90038654) rs35303290 0.273026623126548 0.0805637275567476 0.0007016023529883
Coffee Joint disorder (ebi-a-GCST90038654) rs476828 0.0920564276696203 0.0444570825718749 0.0383886348955996
Coffee Joint disorder (ebi-a-GCST90038654) rs763030 -0.265153213264872 0.0811288346756327 0.0010819635560786
Coffee Joint disorder (ebi-a-GCST90038654) rs76852278 -0.173445186871283 0.0819535208165064 0.0343120926138587
Coffee Joint disorder (ebi-a-GCST90038654) rs780093 -0.24956632940911 0.0513141008763681 1.15325755937502e-06
Coffee Joint disorder (ebi-a-GCST90038654) rs78308709 -0.20732472597276 0.0808715691198629 0.0103584103944178
Coffee Joint disorder (ebi-a-GCST90038654) rs8056750 0.219848480533166 0.0682742350450476 0.0012815494741194
Coffee Osteoporosis (ebi-a-GCST90038656) rs10938398 -0.0741442652508467 0.0341583862204866 0.0299612623576507
Coffee Osteoporosis (ebi-a-GCST90038656) rs11206378 0.101390298637155 0.033447512448462 0.0024348258238287
Coffee Osteoporosis (ebi-a-GCST90038656) rs11678584 -0.0714822636817903 0.0294021215043394 0.0150491510226266
Coffee Osteoporosis (ebi-a-GCST90038656) rs13378244 -0.0816932771298721 0.0326459562150365 0.0123354080487534
Coffee Osteoporosis (ebi-a-GCST90038656) rs1338549 -0.0693703769147019 0.027036114952477 0.0102925945113567
Coffee Osteoporosis (ebi-a-GCST90038656) rs13387939 -0.0458931009072349 0.0203585450416168 0.0241809058442859
Coffee Osteoporosis (ebi-a-GCST90038656) rs1527961 -0.0685629276554924 0.0275757507625664 0.0129061494187538
Coffee Osteoporosis (ebi-a-GCST90038656) rs2472297 -0.0137452550849135 0.0063178167795691 0.0295826614804904
Coffee Osteoporosis (ebi-a-GCST90038656) rs56349356 -0.0971948005869113 0.0348182533845341 0.0052466004678397
Coffee Osteoporosis (ebi-a-GCST90038656) rs73123665 -0.105528621298917 0.0337797355212237 0.0017839739809915
Coffee Osteoporosis (ebi-a-GCST90038656) rs780093 -0.0671748598939331 0.0197026366269229 0.0006509757669024
Coffee Osteoporosis (ebi-a-GCST90038656) All - Inverse variance weighted -0.006627206068674 0.0026847805950272 0.0135705340731182
Coffee Osteoarthritis (ebi-a-GCST90038686) rs117968677 -0.130760331164458 0.0611858239955656 0.0325897171526457
Coffee Osteoarthritis (ebi-a-GCST90038686) rs13054099 -0.131662599627008 0.0579992020560973 0.0232029690646981
Coffee Osteoarthritis (ebi-a-GCST90038686) rs2231142 0.195405216173639 0.0687254745954203 0.0044652947787889
Coffee Osteoarthritis (ebi-a-GCST90038686) rs2472297 0.0560199092763628 0.0136082443168613 3.84476720355263e-05
Coffee Osteoarthritis (ebi-a-GCST90038686) rs35303290 0.184075118098394 0.0666244710354147 0.0057294617802316
Coffee Osteoarthritis (ebi-a-GCST90038686) rs442355 0.146162410659771 0.0560751355816543 0.0091460584171463
Coffee Osteoarthritis (ebi-a-GCST90038686) rs763030 -0.176455460856118 0.0670900339701653 0.0085352410504118
Coffee Osteoarthritis (ebi-a-GCST90038686) rs7743687 -0.150709629698118 0.0689139162811208 0.0287479324519113
Coffee Osteoarthritis (ebi-a-GCST90038686) rs9296406 0.144122318891404 0.0709508104567748 0.0422246605336663
Coffee Osteoarthritis (ebi-a-GCST90038686) All - Inverse variance weighted 0.0118321226989908 0.0059317886167645 0.0460759047719993
Coffee Fracture of forearm or wrist (ebi-a-GCST90038705) rs11206378 -0.0634020255039203 0.0184131453743606 0.0005746566109462
Coffee Fracture of forearm or wrist (ebi-a-GCST90038705) rs11236225 -0.0414573795402186 0.0172572913092495 0.0162918540418933
Coffee Fracture of forearm or wrist (ebi-a-GCST90038705) rs2465037 0.0314155779414393 0.0139746230612226 0.0245733368513882
Coffee Fracture of forearm or wrist (ebi-a-GCST90038705) rs2472297 0.0098030591253001 0.0034778183289291 0.0048212834416284
Coffee Fracture of forearm or wrist (ebi-a-GCST90038705) rs516636 -0.03013865218769 0.0147877396867266 0.0415415564106361
Coffee Fracture of forearm or wrist (ebi-a-GCST90038705) rs61928609 -0.0269176199042802 0.0127104986253012 0.0341965029435631
Coffee Fracture of forearm or wrist (ebi-a-GCST90038705) rs641727 0.0339507640918937 0.0161060268821275 0.0350349669557909
Coffee Fracture of forearm or wrist (ebi-a-GCST90038705) rs73228435 -0.0375941706747542 0.016856620554279 0.0257320602226207
Coffee Fracture of forearm or wrist (ebi-a-GCST90038705) rs78267637 -0.0428665258653578 0.0149272985420378 0.0040828742465048
Coffee Fracture of lower leg or ankle (ebi-a-GCST90038707) rs10193706 0.0605090945680464 0.0183567564118453 0.0009797269023346
Coffee Fracture of lower leg or ankle (ebi-a-GCST90038707) rs10992783 -0.0478234403574643 0.0197626000645451 0.0155249389423421
Coffee Fracture of lower leg or ankle (ebi-a-GCST90038707) rs117968677 -0.0364757862577707 0.0165797827256936 0.0278057642044937
Coffee Fracture of lower leg or ankle (ebi-a-GCST90038707) rs13437947 0.0545430520853354 0.0196913319238901 0.0056073227522258
Coffee Fracture of lower leg or ankle (ebi-a-GCST90038707) rs1527961 -0.040264106541958 0.0160967841056426 0.0123711819456482
Coffee Fracture of lower leg or ankle (ebi-a-GCST90038707) rs56791931 -0.0591039113178186 0.0187494098928191 0.0016198541438958
Coffee Fracture of lower leg or ankle (ebi-a-GCST90038707) All - MR Egger -0.0066539062126406 0.0030784333093433 0.0327511728522056
Coffee Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) rs117810762 -13.3644865018408 6.02362665211119 0.026508654958734
Coffee Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) rs17842490 13.6888038735131 5.39980473030865 0.0112429559847638
Coffee Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) rs1942965 9.603083769216 4.76223101537729 0.0437467327353759
Coffee Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) rs2372891 14.9471217401755 6.14838532456607 0.0150545312876043
Coffee Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) rs4615895 -8.32616267158369 4.05654578979717 0.0401186434775804
Coffee Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) rs9398171 8.08642714387025 3.96953314237822 0.0416377206008495
Coffee Benign neoplasm of bone and articular cartilage (finn-b-CD2_BENIGN_BONE_CARTILAGE) All - MR Egger -1.99666270105014 0.856099166095302 0.0214256615153021
Coffee Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) rs117810762 -13.319928930674 6.04312058949667 0.0275139749688418
Coffee Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) rs17842490 13.5891764799649 5.45072539812213 0.0126634943443094
Coffee Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) rs1942965 9.44584029229316 4.77346269230035 0.0478358783691256
Coffee Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) rs2372891 14.8827407420125 6.15911549092657 0.0156758513139241
Coffee Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) rs4615895 -8.39991804958 4.06474083179676 0.0387782497462702
Coffee Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) rs9398171 8.51008961382245 3.96953314237822 0.0320447866860671
Coffee Benign neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-CD2_BENIGN_BONE_CARTILAGE_EXALLC) All - MR Egger -2.00307318963597 0.854088847071101 0.020726918902427
Coffee Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) rs1182580 13.0225092558242 6.0065062071437 0.0301535719487509
Coffee Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) rs13437947 12.0507399577167 5.48721891216606 0.0280814155570805
Coffee Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) rs4615895 10.3913132554804 4.58102847777095 0.0233087161421327
Coffee Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) rs4840338 -23.7854685446753 9.65417962585101 0.0137492629813065
Coffee Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) rs57918684 8.31108765830643 4.17494412714179 0.0465131835349618
Coffee Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) rs77350503 -13.2841105092747 4.92480406693497 0.0069885656385159
Coffee Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) rs10992783 25.5294139254688 11.8201448853275 0.0307864193677573
Coffee Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) rs73228435 38.7613846740657 14.9547403968704 0.0095443930106271
Coffee Pain in joint (finn-b-JOINTPAIN) rs11206378 -4.84841463138196 1.82602628974126 0.0079267882287121
Coffee Pain in joint (finn-b-JOINTPAIN) rs12649199 -3.53958415213346 1.77571111311043 0.0462249586619297
Coffee Pain in joint (finn-b-JOINTPAIN) rs13054099 3.00620726128951 1.5309388830641 0.0495722772211629
Coffee Pain in joint (finn-b-JOINTPAIN) rs1942965 -3.47058816922543 1.58366644615141 0.0284163987470917
Coffee Pain in joint (finn-b-JOINTPAIN) rs34715167 -4.65339479692294 1.72078661761213 0.0068463840614181
Coffee Pain in joint (finn-b-JOINTPAIN) rs4938000 -4.0332059333471 1.6944237944831 0.0172994081285744
Coffee Pain in joint (finn-b-JOINTPAIN) rs73123665 4.20622741751087 2.07865889818851 0.0430185943840388
Coffee Pain in joint (finn-b-JOINTPAIN) rs7811609 -3.32653436397538 1.54289916223858 0.031081450050783
Coffee Pain in joint (finn-b-JOINTPAIN) All - MR Egger 0.610853844992304 0.274122539196909 0.027798597768435
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs1057868 1.65406071906531 0.58643970948679 0.0047946957544164
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs10938398 3.90919498506129 1.52910688191173 0.0105724464713832
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs11236225 3.33316994264987 1.39208862310671 0.0166491168626043
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs13387939 3.83551383805071 0.942267966513246 4.69097593022556e-05
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs13437947 3.37305400730348 1.34537766673073 0.0121711509635067
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs1421085 3.79126983270954 0.625586487331874 1.35830034229839e-09
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs144620429 4.47018492369727 1.37427982451504 0.0011429511058213
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs2189234 -3.24425321596613 1.19156213796287 0.006475296817134
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs55780162 -3.97137037817406 1.53236156071025 0.009551226494181
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs56113850 1.83946884350304 0.907892347651717 0.0427558744963186
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs56791931 3.68926267200532 1.52990750616334 0.015890164041493
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs75347775 3.1290668299778 1.26310954604608 0.0132390695402817
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs76881016 4.5300887375407 1.99473043175661 0.0231452807224461
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs780093 -1.82043856019859 0.910219280099297 0.0455002638963584
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs9650210 -3.93342944900646 1.31636682755595 0.0028072206264588
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) rs9953004 3.19071311802588 1.55086454342294 0.0396499710611941
Coffee Gonarthrosis [arthrosis of knee](FG) (finn-b-KNEE_ARTHROSIS) All - Inverse variance weighted 0.387609412150126 0.145305557294613 0.0076407187756135
Coffee Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs11236225 12.0582324395863 4.34292436645262 0.0054943628845281
Coffee Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs4938000 -12.5172574676956 4.45084560100138 0.0049183641489544
Coffee Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs56791931 9.49416886681937 4.77331141922963 0.04669999004373
Coffee Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs61928609 -15.8310987407081 4.37188147041852 0.0002933326647591
Coffee Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs7590617 -13.7922203340545 4.82861098735758 0.0042853759449183
Coffee Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs7811609 8.19596789018935 4.03779993522012 0.0423758257796099
Coffee Achilles tendinitis (finn-b-M13_ACHILLESTEND) rs9650210 -8.52504231179089 4.10581081928164 0.0378628972430846
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs13387939 4.27644692494473 1.40132159122483 0.0022753110389185
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs1421085 4.85368826378178 0.93837973099781 2.31089124212721e-07
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs144620429 5.91997462868016 2.06141973677256 0.0040814780475456
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs2189234 -5.19681302187167 1.77232351612965 0.0033656624794194
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs2231142 5.23526884458094 2.60172175103035 0.0441954429138822
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs2465037 4.4865825785152 1.77770253110979 0.0116090811467694
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs476828 3.0381469033385 1.27406160462582 0.0170969855522096
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs56113850 3.1657811426812 1.35789116344431 0.0197325225646819
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs56791931 5.85736016645394 2.28174776633504 0.0102567878245308
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) rs9953004 4.83056169262882 2.31358481068012 0.0368057655775258
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) All - Inverse variance weighted 0.667207371801397 0.186892324492389 0.0003569682971955
Coffee Gonarthrosis, primary, with knee surgery (finn-b-M13_ARTHROSIS_KNEE_PRIM_KNEESURG) All - MR Egger 0.847561439280146 0.406342983241557 0.0392057679244938
Coffee Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs10053913 -25.5832820790186 12.8993349303939 0.0473336601679641
Coffee Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs56791931 30.816708338433 13.3058241393177 0.0205565468057746
Coffee Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs641727 -29.2753471714895 11.3368648609448 0.0098140189278477
Coffee Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs73228435 36.0495297280703 16.5827836749123 0.0297116662879534
Coffee Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs77350503 27.0296849940993 10.4926317063576 0.0099932307539252
Coffee Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) rs78308709 -26.732058971253 11.7410701096109 0.0227982196401161
Coffee Impingement syndrome of shoulder (finn-b-M13_IMPINGEMENT) rs11032480 -5.93781315038927 2.85448624065367 0.0375100550548144
Coffee Impingement syndrome of shoulder (finn-b-M13_IMPINGEMENT) rs13054099 -5.79901092069737 2.2917691158596 0.0113944127758626
Coffee Impingement syndrome of shoulder (finn-b-M13_IMPINGEMENT) rs4970968 -8.88096129829884 2.70562431654802 0.0010292478146422
Coffee Impingement syndrome of shoulder (finn-b-M13_IMPINGEMENT) rs76852278 -5.62082384903444 2.21381892943682 0.0111178781916925
Coffee Impingement syndrome of shoulder (finn-b-M13_IMPINGEMENT) rs9953004 -7.70347469929754 2.796640979943 0.0058773725356766
Coffee Impingement syndrome of shoulder (finn-b-M13_IMPINGEMENT) All - MR Egger 1.0339423018587 0.420523247164843 0.0154339546701487
Coffee Loose body in joint (finn-b-M13_LOOSEJOINT) rs11678584 25.7895869362513 8.94187779433681 0.0039248986744419
Coffee Loose body in joint (finn-b-M13_LOOSEJOINT) rs1421085 9.22740068814514 4.10406307637548 0.0245534077327848
Coffee Loose body in joint (finn-b-M13_LOOSEJOINT) rs329122 23.2349537697457 8.67316545432551 0.0073854001460537
Coffee Loose body in joint (finn-b-M13_LOOSEJOINT) rs4938000 -22.0513744521463 9.30739830772407 0.0178251275879837
Coffee Loose body in joint (finn-b-M13_LOOSEJOINT) All - Inverse variance weighted 1.37380027538453 0.692054930400042 0.0471330200306659
Coffee Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) rs10053913 -13.9882398271154 6.48556542882511 0.0310191801882641
Coffee Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) rs116814395 24.1313116672382 11.563656674998 0.0369040828863607
Coffee Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) rs13096450 15.0509456407427 7.05997965622468 0.0330176886897926
Coffee Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) rs13378240 -16.6320979924079 6.72189981146452 0.0133491912367875
Coffee Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) rs2465037 -10.8449260231195 5.21083175785622 0.0374130933445877
Coffee Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) rs71429826 -16.9852772403843 7.82590637330448 0.0299772333735543
Coffee Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) rs7590617 13.5254462463552 6.77606182756256 0.0459270666371326
Coffee Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) rs78267637 8.42448054936108 4.21224027468054 0.0455002638963584
Coffee Olecranon bursitis (finn-b-M13_OLECRANONBURSITIS) All - MR Egger 2.18154690346647 1.02791158081656 0.0359574229113136
Coffee Osteomalacia (finn-b-M13_OSTEOMALACIA) rs1057868 -13.4931256234055 6.64130440230767 0.0421842270568458
Coffee Osteomalacia (finn-b-M13_OSTEOMALACIA) rs2126069 36.5576501693196 14.8041505948824 0.0135332668135675
Coffee Osteomalacia (finn-b-M13_OSTEOMALACIA) rs2472297 -8.97122494125343 3.24074472572024 0.0056356425792132
Coffee Osteomalacia (finn-b-M13_OSTEOMALACIA) rs4615895 27.3058799426347 12.7023150993649 0.0315807397879927
Coffee Osteomalacia (finn-b-M13_OSTEOMALACIA) rs56349356 -35.7062338996707 16.3655112004701 0.0291244700045203
Coffee Osteomalacia (finn-b-M13_OSTEOMALACIA) rs6030315 36.8652419329873 16.7428565531902 0.0276759766218931
Coffee Osteomalacia (finn-b-M13_OSTEOMALACIA) rs6062682 39.9791714880815 13.5192470878655 0.0031044265925241
Coffee Osteomalacia (finn-b-M13_OSTEOMALACIA) rs6544966 -34.9520671980029 16.6383605651671 0.0356680317576959
Coffee Osteomalacia (finn-b-M13_OSTEOMALACIA) rs6691876 40.8078179877456 14.6685497126318 0.005402603097024
Coffee Osteomalacia (finn-b-M13_OSTEOMALACIA) rs75347775 29.4725560744086 14.2482584398683 0.038592809806785
Coffee Osteomalacia (finn-b-M13_OSTEOMALACIA) All - MR Egger -6.95905928525667 2.79037127823021 0.014054579590562
Coffee Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs10193706 -17.3264927227503 7.65703361118712 0.0236467558810973
Coffee Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs11032480 -22.9201996454174 8.00942341786788 0.0042143652662252
Coffee Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs11678584 16.202172509703 6.91760242913044 0.0191721907234727
Coffee Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs117514553 17.8032804440558 8.49113851755341 0.0360210761176681
Coffee Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs6030315 -16.6267658683067 7.52009658744982 0.0270373812348042
Coffee Osteonecrosis (finn-b-M13_OSTEONECROSIS) rs6691876 -13.3806859729811 6.58120199160487 0.0420356037445126
Coffee Osteonecrosis (finn-b-M13_OSTEONECROSIS) All - MR Egger 2.4990623059913 1.16719381722457 0.0343781495013891
Coffee Short Achilles tendon (acquired) (finn-b-M13_SHORTACHILLES) rs117810762 -31.3295422266532 13.5928440540706 0.0211746640748291
Coffee Short Achilles tendon (acquired) (finn-b-M13_SHORTACHILLES) rs12649199 -23.1434348408726 10.3109625301279 0.024797260691362
Coffee Short Achilles tendon (acquired) (finn-b-M13_SHORTACHILLES) rs17842490 23.6006225605126 11.3663786328022 0.0378612482179131
Coffee Short Achilles tendon (acquired) (finn-b-M13_SHORTACHILLES) rs2126069 -26.4505351225077 9.11111714746202 0.0036948204000036
Coffee Shoulder lesions (finn-b-M13_SHOULDER) rs10938398 3.88260182189761 1.58229320823909 0.0141362842667435
Coffee Shoulder lesions (finn-b-M13_SHOULDER) rs12514566 -3.00073702312849 1.22837188081283 0.0145715040034927
Coffee Shoulder lesions (finn-b-M13_SHOULDER) rs62121718 -4.30414598570067 1.5485816244849 0.0054457445934671
Coffee Shoulder lesions (finn-b-M13_SHOULDER) rs6937318 -2.8359213567236 1.43561164116299 0.048221657477716
Coffee Shoulder lesions (finn-b-M13_SHOULDER) rs6969878 2.96583691627573 1.41763273985507 0.0364291004547763
Coffee Shoulder lesions (finn-b-M13_SHOULDER) rs9953004 -5.0339537638974 1.61442456569437 0.0018201471083741
Coffee Shoulder lesions (finn-b-M13_SHOULDER) All - MR Egger 0.583076783224431 0.245291353202929 0.0191011104644415
Coffee Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) rs1057868 15.8188352405155 6.19019693347167 0.0106045846463964
Coffee Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) rs16930598 37.1976985827159 17.81087563906 0.0367543500863704
Coffee Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) rs35303290 -33.9881821848602 15.4502095349213 0.0278173612065857
Coffee Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) rs4877113 -32.6431555132793 15.7711342476056 0.0384707099995459
Coffee Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) rs55780162 33.1628581097043 16.0897963874576 0.0392924410347117
Coffee Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) rs56212739 -37.1925931260136 18.3985175703814 0.04322808935394
Coffee Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) rs8068193 36.1455058870199 16.0110237268496 0.0239744333530622
Coffee Tibial collateral bursitis [Pellegrini-Stieda] (finn-b-M13_TIBIALCOLLATERAL) All - MR Egger 4.86831024223815 2.41645190662541 0.046274209827672
Coffee Transient synovitis (finn-b-M13_TRANSSYNOVITIS) rs1338549 -41.0846865110393 14.9293053482041 0.0059241751090904
Coffee Transient synovitis (finn-b-M13_TRANSSYNOVITIS) rs144620429 -34.6590351347474 16.3780930734787 0.0343292828224367
Coffee Transient synovitis (finn-b-M13_TRANSSYNOVITIS) rs4938000 36.4181790194537 16.944237944831 0.0316109612532881
Coffee Transient synovitis (finn-b-M13_TRANSSYNOVITIS) rs4970968 -36.3004595803527 17.8245527891104 0.0416959083874831
Coffee Transient synovitis (finn-b-M13_TRANSSYNOVITIS) rs55716899 39.1638300833892 17.6142331102028 0.0261875232979542
Coffee Transient synovitis (finn-b-M13_TRANSSYNOVITIS) rs6937318 -35.5961083157216 16.3565588624308 0.0295358999761002
Coffee Transient synovitis (finn-b-M13_TRANSSYNOVITIS) rs76852278 29.3083192598576 14.0612379763566 0.0371297781958501
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs11236225 4.61742071467085 1.39208862310671 0.0009102173023041
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs13163336 2.45530935559837 1.17747805609077 0.0370486754091792
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs13387939 2.34962973701059 0.936227787240725 0.0120841494463823
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs13437947 4.12262156448203 1.34537766673073 0.0021819042127028
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs1421085 1.97383322727126 0.625586487331874 0.0016040328429287
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs144620429 4.06243156917083 1.37427982451504 0.0031161267777596
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs1527961 -2.79545233116742 1.28905576665093 0.0301127117611576
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs2189234 -2.49326867523323 1.1815490107531 0.0348437593608861
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs2231142 4.20094521267285 1.73448116735356 0.0154345711980951
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs2465037 3.18857755580011 1.18513502073986 0.0071350126253214
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs2521501 3.41234274607203 1.40381188920685 0.0150668074948415
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs34060476 -1.85032448505632 0.917022985262518 0.0436171504662018
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs4840338 -5.6261019433824 2.33760573703916 0.0160938765652797
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs55716899 -3.83413263821226 1.48050666227998 0.0096047443174282
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs55895231 5.85194741679526 1.88038079819214 0.0018575676587744
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs56791931 3.09478432675327 1.52116517755669 0.0419029452259953
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) rs75347775 3.7414835795759 1.26310954604608 0.0030552748022957
Coffee Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) All - Inverse variance weighted 0.301372700232794 0.136768557382605 0.0275578879614547
Coffee Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) rs12649199 -10.2636102337783 4.27354474555244 0.016320778505082
Coffee Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) rs6937318 -11.7555412255887 4.00088490160177 0.0033008640126782
Coffee Seronegative rheumatoid arthritis (finn-b-RHEUMA_SERONEG) All - MR Egger 1.39884272289515 0.659493784213065 0.0360625465130681
Coffee Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) rs11032480 -7.37107839358668 2.8183535034302 0.0089127029378383
Coffee Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) rs13088645 -6.4763580677747 2.6834312312692 0.0158017955474975
Coffee Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) rs1421085 2.71267244075804 1.11634830066981 0.0151008354557703
Coffee Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) rs6937318 -6.74266779005239 2.4711347921658 0.0063609312666151
Coffee Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) rs9296406 6.27891265220239 2.66886020329753 0.0186398188691238
Coffee Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) rs10938398 3.72304284291552 1.80833509513039 0.039511146777562
Coffee Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) rs11678584 -3.77758473664496 1.60985678650271 0.018948904060518
Coffee Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) rs2126069 3.68971949077344 1.55058763876062 0.017333224823245
Coffee Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) rs4615895 2.74533906986273 1.32759680393362 0.0386493113132997
Coffee Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) rs4937720 4.27844414753877 1.93906094405997 0.0273523946261215
Coffee Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) rs4938000 -3.81841981855346 1.68249123255012 0.0232377218253262
Coffee Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) rs55895231 5.9362694256828 2.20923663285354 0.0072092009863737
Coffee Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) rs75347775 3.61708642731379 1.49276582714537 0.0153896675618411
Coffee Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) All - Inverse variance weighted 0.269018984521738 0.132035196365712 0.0416020304118757
Coffee Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) rs117810762 6.54439326512312 3.14409361545702 0.0373892574613472
Coffee Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) rs13088645 -6.9278969768825 2.83824457153473 0.0146503422314068
Coffee Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) rs2472297 1.09315957547535 0.537972232025272 0.0421536559466274
Coffee Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) rs6062682 5.31319910514541 2.2467792949163 0.0180394755771661
Coffee Dislocation, sprain and strain of joints and ligaments of shoulder girdle (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_SHOUL_GIRDLE) All - Inverse variance weighted 0.501976229429126 0.19935096586093 0.0118005677334798
Coffee Fracture of femur (finn-b-ST19_FRACT_FEMUR) rs13378244 -7.2113130166101 2.95296297516723 0.0146037158071057
Coffee Fracture of femur (finn-b-ST19_FRACT_FEMUR) rs4410790 1.4025389025389 0.632166257166257 0.0265123506587344
Coffee Fracture of femur (finn-b-ST19_FRACT_FEMUR) rs4877113 6.87745148366172 3.0429011960086 0.0238111610058829
Coffee Fracture of femur (finn-b-ST19_FRACT_FEMUR) rs6937318 6.17783698041449 2.80061943112124 0.0273922381359285
Coffee Fracture of femur (finn-b-ST19_FRACT_FEMUR) rs7811609 5.25242267996113 2.62621133998057 0.0455002638963584
Coffee Fracture of femur (finn-b-ST19_FRACT_FEMUR) rs8068193 -6.9028782000843 3.06649598680493 0.024381494906123
Coffee Fracture of femur (finn-b-ST19_FRACT_FEMUR) All - MR Egger 1.06224732972306 0.485963041337192 0.0308524462618608
Coffee Fracture of shoulder and upper arm (finn-b-ST19_FRACT_SHOUL_UPPER_ARM) rs2189234 4.52593349881695 1.97258606032509 0.0217666009976658
Coffee Fracture of shoulder and upper arm (finn-b-ST19_FRACT_SHOUL_UPPER_ARM) rs34276507 5.16573615557263 2.58286807778632 0.0455002638963584
Coffee Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs12930957 3.40726244044869 1.57631358454922 0.0306537692627245
Coffee Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs2350804 3.27885730144449 1.48835502079221 0.0275942187052692
Coffee Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs2577374 4.19620574659334 1.41810831325315 0.0030862268309858
Coffee Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) rs723145 -4.00055783859938 1.48621232680791 0.0071071635815377
Coffee Injuries to the shoulder and upper arm (finn-b-ST19_INJURI_SHOUL_UPPER_ARM) All - Inverse variance weighted 0.229659002126584 0.11066191136605 0.0379567830795131
Coffee Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) rs1527961 -37.0978258425703 14.5543389467215 0.0108057506052497
Coffee Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) rs2372891 40.1415523546277 19.1211564544097 0.0357881201920707
Coffee Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) rs2472297 7.98135603432693 3.18264372466151 0.0121493821812877
Coffee Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) rs4877113 -34.9438856858712 16.6864785098195 0.0362471714216432
Coffee Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) rs6544966 -46.3725560409654 16.4848937498082 0.0049076559542542
Coffee Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) rs7811609 29.7856136142796 14.3785070863936 0.0383086133180393
Coffee Open wound of neck (finn-b-ST19_OPEN_WOUND_NECK) rs8056750 24.9304586406919 12.4177608156988 0.0446810013977709
Coffee Knee and hip osteoarthritis (ieu-a-1170) rs1338549 5.16232313111231 2.32606195397203 0.0264635790458348
Coffee Knee and hip osteoarthritis (ieu-a-1170) rs13387939 4.38340037932326 1.65843994249749 0.0082154021310112
Coffee Knee and hip osteoarthritis (ieu-a-1170) rs1421085 4.15049669409899 1.27476729261269 0.00113039217719
Coffee Knee and hip osteoarthritis (ieu-a-1170) rs2231142 7.50367582706109 2.68038604140477 0.0051185654935016
Coffee Knee and hip osteoarthritis (ieu-a-1170) rs2472297 1.04991091179838 0.523205970200642 0.0447829414196219
Coffee Knee and hip osteoarthritis (ieu-a-1170) rs34060476 -3.93781064831897 1.78858550561066 0.0276911727374648
Coffee Knee and hip osteoarthritis (ieu-a-1170) All - Inverse variance weighted 0.708263540253727 0.263070802277154 0.0070962684434449
Coffee Knee osteoarthritis (ieu-a-1171) rs13378244 9.75377611724657 3.59601185240762 0.0066800535049508
Coffee Knee osteoarthritis (ieu-a-1171) rs1421085 3.14243417859416 1.42223852102726 0.0271399719848267
Coffee Knee osteoarthritis (ieu-a-1171) rs2472297 1.4559379223082 0.664658237000439 0.0284875529203928
Coffee Knee osteoarthritis (ieu-a-1171) rs329122 9.51555806113669 3.4661050411633 0.006045242102079
Coffee Knee osteoarthritis (ieu-a-1171) rs641727 6.59899386657481 3.17048277127155 0.0373987213909691
Coffee Knee osteoarthritis (ieu-a-1171) rs7585210 8.33813141147299 3.84232397872414 0.030001160722457
Coffee Knee osteoarthritis (ieu-a-1171) rs8056750 5.53187510087057 2.74466691350289 0.0438523266124737
Coffee Knee osteoarthritis (ieu-a-1171) rs9953004 -7.8656036041075 3.45311431397126 0.0227367733165292
Coffee Knee osteoarthritis (ieu-a-1171) All - Inverse variance weighted 0.773700778850085 0.328725717678428 0.0185907912905606
Coffee Rheumatoid arthritis (ieu-a-831) rs1057868 2.44551373622243 1.21868186397606 0.044782941419622
Coffee Rheumatoid arthritis (ieu-a-831) rs17842490 -1.90792436288282 0.830529375690473 0.0216051469858999
Coffee Rheumatoid arthritis (ieu-a-831) rs329122 9.51555806113669 2.83478989256687 0.0007887675416816
Coffee Rheumatoid arthritis (ieu-a-831) rs35303290 -8.76890542785459 3.48676819444476 0.0119063041979649
Coffee Rheumatoid arthritis (ieu-a-831) rs56212739 -7.3604922769839 3.34319523626476 0.0276911727374648
Coffee Rheumatoid arthritis (ieu-a-831) rs6937318 -30.7556259502102 3.12163160793211 6.691304356933021e-23
Coffee Rheumatoid arthritis (ieu-a-831) rs7585210 6.32129952331422 2.99639158233058 0.0348896067556698
Coffee Rheumatoid arthritis (ieu-a-831) rs9953004 9.78328574806333 3.89011489109626 0.0119063041979649
Coffee Psoriatic arthritis (ieu-b-5116) rs10193706 -6.37554804849946 2.97384951229359 0.0320432696799023
Coffee Psoriatic arthritis (ieu-b-5116) rs116814395 6.78946791624391 2.78641349882808 0.0148247043945453
Coffee Psoriatic arthritis (ieu-b-5116) rs13378240 7.15180213673541 2.93450061118644 0.0148037608131357
Coffee Psoriatic arthritis (ieu-b-5116) rs13387939 4.87984875391102 2.14976020488288 0.0232106006296489
Coffee Psoriatic arthritis (ieu-b-5116) rs2465037 5.75158253148603 2.29530554850118 0.0122173818914543
Coffee Psoriatic arthritis (ieu-b-5116) rs4836963 -6.29576487796786 2.95048594198855 0.0328586570056779
Coffee Psoriatic arthritis (ieu-b-5116) rs4984636 7.10346558288142 3.27889923979973 0.0302792771767476
Coffee Psoriatic arthritis (ieu-b-5116) rs55780162 7.27765752996086 3.59287707267863 0.0428079115858922
Coffee Psoriatic arthritis (ieu-b-5116) rs56212739 -7.43435005258893 2.91678372816444 0.0108088779213111
Coffee Psoriatic arthritis (ieu-b-5116) rs6030315 -10.5177386566502 3.54811829898769 0.0030335803947671
Coffee Psoriatic arthritis (ieu-b-5116) rs6937318 -24.0143702371819 3.55984617774284 1.52080191087135e-11
Coffee Psoriatic arthritis (ieu-b-5116) rs7224815 4.71423178210346 2.19977532642124 0.0321089643983335
Coffee Psoriatic arthritis (ieu-b-5116) rs73075167 5.12434713861516 2.22884853615872 0.0214992240935521
Coffee Psoriatic arthritis (ieu-b-5116) rs78308709 6.68904186486247 2.64584749017638 0.0114672444836012
Coffee Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) rs1057868 0.0417090457072112 0.0141218691888586 0.0031418503565901
Coffee Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) rs11206378 -0.0952794072088999 0.0335006561101358 0.004453626990301
Coffee Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) rs116814395 0.0854678313989868 0.0341580731716802 0.0123449690888848
Coffee Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) rs13054099 -0.0632230438776362 0.0268834723549551 0.0186856317089983
Coffee Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) rs144620429 0.101160586862791 0.0334141037354738 0.0024660066248384
Coffee Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) rs2472297 0.0161419644163647 0.0061910705217039 0.0091259957766149
Coffee Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) rs61928609 -0.0498706764875598 0.0233304368487153 0.0325508419182332
Coffee Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) rs6937318 -0.172580523692299 0.029943446315185 8.23632668348969e-09
Coffee Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) rs7224815 0.0534434909117696 0.0238890628165227 0.0252763355136852
Coffee Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) rs7590617 -0.0846182062643891 0.0339775482927792 0.0127593902750349
Coffee Non-cancer illness code self-reported: rheumatoid arthritis (ukb-a-105) All - MR Egger 0.0125201059502756 0.0062644490363469 0.0480318770538976
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs13163336 0.141516805823164 0.0619098560265468 0.0222628828158072
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs13387939 0.14431135916114 0.0539197139371097 0.0074415147205039
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs1421085 0.100086827090052 0.0370565616472339 0.0069147864452062
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs2231142 0.234358639784861 0.0843713699218688 0.005474456713473
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs2350804 0.173828675789276 0.0859709670055192 0.0431819032717055
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs2472297 0.0598453222238481 0.0163713772949895 0.0002566963348095
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs329122 0.188853612944015 0.0780213998945526 0.0154976415567893
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs35303290 0.163976172951195 0.0813373774294771 0.043799950009463
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs476828 0.108780071601109 0.0455688022091421 0.0169790495580193
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs73075167 0.147466679946962 0.063449100156251 0.0201162284357842
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs76852278 -0.194156692855569 0.0835340333357809 0.0201103574645211
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs76881016 -0.160315428400984 0.0812948969699983 0.0486069503726351
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs7743687 -0.21652210917617 0.0848228266886674 0.010691004675842
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) rs8056750 0.14832768458128 0.0687556606191792 0.0309810536276931
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) All - Inverse variance weighted 0.0236141877316924 0.0072719441666678 0.0011650532088475
Coffee Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) All - MR Egger 0.0464760693677261 0.0157146990078685 0.0037712958783866
Coffee Fracture resulting from simple fall (ukb-a-332) rs4984636 -1.05463893547479 0.490296123101029 0.0314742719938139
Coffee Fracture resulting from simple fall (ukb-a-332) rs6469262 -1.03049226140469 0.415013104320001 0.0130268113111085
Coffee Fracture resulting from simple fall (ukb-a-332) rs6969878 -0.938640751345352 0.427336062898126 0.0280566621742278
Coffee Fracture resulting from simple fall (ukb-a-332) rs7224815 0.751405130660577 0.353153717242776 0.0333619727989053
Coffee Fracture resulting from simple fall (ukb-a-332) rs763030 1.00677665702296 0.469716162327 0.0320832076770536
Coffee Fracture resulting from simple fall (ukb-a-332) rs7743687 -1.52188988026444 0.4767753781669 0.0014126786688418
Coffee Fracture resulting from simple fall (ukb-a-332) All - MR Egger -0.147759287305072 0.0741637766832512 0.048723912978243
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs11206378 -0.365390379234177 0.131160320070925 0.0053390832949759
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs12930957 -0.26938107865926 0.126028696182532 0.0325607365279947
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs1338549 -0.327160226045131 0.106099642268027 0.0020456828530163
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs13387939 0.211095205305693 0.0798288213194168 0.008184839386212
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs1421085 0.153318304876339 0.0548628563416134 0.0051968166085657
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs2472297 0.094315785396421 0.024238446508345 9.97642172680692e-05
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs2595223 -0.289934702112365 0.124859709209962 0.0202284263529718
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs2597805 -0.220976720493718 0.110242292760441 0.0450203665490031
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs329122 0.32356156692146 0.115511728173865 0.0050926459605756
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs34060476 0.172410630955223 0.0794597703644217 0.030023124717231
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs476828 0.189409723223088 0.0674693446941964 0.0049951722168599
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs4840338 0.274981675548248 0.132776005863825 0.0383569890791585
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs55716899 -0.288696268363977 0.127929694914396 0.0240281339307257
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs6030315 0.589638777384503 0.131753898067219 7.63025856220106e-06
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs6469262 0.322139035797353 0.110008554133023 0.0034081118848766
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs7224815 -0.215895655696948 0.093529585090514 0.0209816753462398
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs7585210 0.305166396363977 0.134697006295013 0.0234773142176461
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) rs9953004 -0.302960117357225 0.133437910756644 0.0231821048667012
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) All - Inverse variance weighted 0.0325555476071461 0.0120383461543016 0.0068444215144583
Coffee Pain type(s) experienced in last month: Knee pain (ukb-a-476) All - MR Egger 0.0990258338828211 0.0253686378072875 0.0001609640104002
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) rs1057868 0.0448276518853786 0.0186526923597432 0.0162487183354235
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) rs1338549 -0.0708385487149265 0.0357928773141217 0.0478020274720512
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) rs1421085 0.0613063971611317 0.0185090548251054 0.0009255272853861
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) rs2472297 0.0255696049992684 0.0081770703323377 0.001766068275553
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) rs2521501 0.0812734733545705 0.0391661357378111 0.0379776815668037
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) rs2595223 -0.137160598976738 0.0421227551963467 0.0011290961926142
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) rs476828 0.0501260225641499 0.0227610817417172 0.0276463192997325
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) rs516636 0.104341123776409 0.0352338417532351 0.0030625451338134
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) rs6937318 0.0937151981850103 0.039551336060211 0.0178142165670262
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) rs780093 0.0605664422462106 0.0260431037725204 0.0200386691862977
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) rs9296406 0.0866032242925587 0.0435643079271594 0.0468183414365307
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) All - Inverse variance weighted 0.0138234843255337 0.0031458662030439 1.11194591021301e-05
Coffee Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] (ukb-a-563) All - MR Egger 0.0263255648771144 0.0067502123860495 0.0001630373006571
Coffee Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs1527961 -0.0532329818408016 0.0264765309410857 0.0443706438320633
Coffee Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs4840338 -0.0845055039389317 0.0318296057106255 0.0079323915573828
Coffee Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs55716899 0.0609970010249661 0.030666354537057 0.0466953657581813
Coffee Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs76881016 0.0637046059009222 0.0288537446247918 0.0272550555266593
Coffee Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) rs7811609 0.0628294800976951 0.0270055500599652 0.0199897854954189
Coffee Diagnoses - main ICD10: S52 Fracture of forearm (ukb-a-590) All - Inverse variance weighted 0.0047240326476122 0.0021601645129679 0.0287508770644772
Coffee Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) rs13088645 -0.0149229739126621 0.006853792991342 0.0294559019494307
Coffee Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) rs13437947 -0.0156593311551028 0.0068487699404189 0.0222282777979425
Coffee Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) rs2189234 0.0110133384867561 0.005352487110602 0.0396274516339854
Coffee Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) rs329122 0.0125538363921458 0.0060286602470026 0.0373096682463253
Coffee Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) rs34276507 0.0138728007450875 0.0070191921094016 0.0481083716792031
Coffee Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) rs476828 0.0070590507376297 0.0035211315511844 0.0449878890540063
Coffee Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) rs62121718 0.0173370544838839 0.0067849282016071 0.0106117545187826
Coffee Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) rs8056750 -0.0105673435675429 0.0053125801031015 0.0466882867951231
Coffee Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) All - Inverse variance weighted 0.0013755399552695 0.0004831121097949 0.004409900253137
Coffee Non-cancer illness code self-reported: osteoporosis (ukb-a-87) rs11206378 0.107436208716064 0.0395832126476877 0.0066438815370433
Coffee Non-cancer illness code self-reported: osteoporosis (ukb-a-87) rs13387939 -0.0564728373138115 0.0240924630643038 0.0190779508234025
Coffee Non-cancer illness code self-reported: osteoporosis (ukb-a-87) rs1421085 -0.0435253416457239 0.0165576024937172 0.0085706276209057
Coffee Non-cancer illness code self-reported: osteoporosis (ukb-a-87) rs4840338 -0.115647695081123 0.0400711847170771 0.0039010236763574
Coffee Non-cancer illness code self-reported: osteoporosis (ukb-a-87) rs73123665 -0.133947556658739 0.0396536587453459 0.0007303183972177
Coffee Non-cancer illness code self-reported: osteoporosis (ukb-a-87) rs780093 -0.0835272877722195 0.0232972505359762 0.0003367100278581
Coffee Non-cancer illness code self-reported: osteoporosis (ukb-a-87) All - Inverse variance weighted -0.0069616393533187 0.003093119369791 0.0244054548175489
Coffee Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) rs12930957 -0.0718654701234011 0.0312915222217776 0.0216391168022065
Coffee Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) rs1338549 -0.07545658174985 0.0263269994000768 0.0041552462183738
Coffee Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) rs2577374 -0.0693545631122131 0.0292411609425073 0.0177010510953606
Coffee Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) rs2595223 -0.0641513992835958 0.0309652127164767 0.0382911126816425
Coffee Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) rs476828 0.0404997088682759 0.0167685531618058 0.0157258010622464
Coffee Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) rs75347775 0.0559786228278343 0.0275787529663936 0.0423795645112283
Coffee Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) rs8068193 0.0679882611923841 0.0330215946562067 0.0395035290682727
Coffee Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) rs11032480 0.0346263634086179 0.0147861182841286 0.0191901903555175
Coffee Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) rs2189234 -0.0277853265631243 0.0116868214228854 0.0174308124856679
Coffee Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) rs2472297 0.0060907924976544 0.0027684696626698 0.0278028143545181
Coffee Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) rs4840338 0.045682495030937 0.0151019896062389 0.0024868884810295
Coffee Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) rs6063085 0.033605940099514 0.0112723570207289 0.002870555594917
Coffee Operative procedures - secondary OPCS: W28.1 Application of internal fixation to bone NEC (ukb-b-10298) All - Inverse variance weighted 0.0031020913679733 0.0013429379865076 0.0208920865590422
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs10938398 1.03338372737753 0.465055918773842 0.0262790225496443
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs11032480 -1.02522787712942 0.450016380174208 0.0227145902057744
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs11206378 -1.5520845664258 0.454552094641054 0.0006389071084988
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs11236225 -0.875503161609725 0.425952649379932 0.0398403660051133
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs12514566 0.870075106166427 0.321170111957323 0.0067470335372934
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs13054099 -1.08103769821019 0.366384293494902 0.0031720163205658
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs13378244 1.6700463095567 0.444964627812602 0.000174583510944
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs13387939 0.933636550332814 0.275435194916585 0.0006997482890256
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs1421085 1.08509054825105 0.189627668180298 1.0514327825991e-08
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs1447365 1.13202920754336 0.4419047916822 0.0104160093649112
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs17842490 0.759793926271301 0.323839949699236 0.0189658273982985
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs2126069 -2.13404999909455 0.393547065428007 5.87369295353987e-08
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs2189234 -0.764684501381311 0.355800454395713 0.0316189579939137
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs2595223 -1.13925786323083 0.430664033005334 0.0081606031661731
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs34060476 0.550371150131313 0.275211078071756 0.045520280345901
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs4615895 1.16874410981356 0.323684490883016 0.0003053116329825
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs476828 0.675679259314774 0.233133672698762 0.0037525343284163
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs4840338 4.28473886830827 0.459425371606675 1.09631216478427e-20
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs516636 1.36542002449322 0.36364212491543 0.0001734483826133
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs55716899 -1.31967555392461 0.443275083199413 0.0029098628891533
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs56791931 0.975582676201633 0.435031384959698 0.0249253959514581
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs57918684 1.19540756146014 0.371150980879066 0.001278279365546
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs6062682 0.787756499267145 0.339124816786238 0.020183976545771
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs62121718 0.978753687844659 0.452056026772243 0.0303788112037954
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs6469262 -1.16200741358195 0.381644338158097 0.0023288228673248
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs6544966 1.02000184160178 0.443324705087937 0.0214028925212724
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs7585210 -1.33073957773626 0.467149596517778 0.0043906959033077
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs763030 -1.01475226105768 0.428204794050443 0.0177985483444231
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs76852278 0.959633600117483 0.431345913796901 0.0260985273262407
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs780093 0.552989054801219 0.266127054575544 0.037717307715264
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs78308709 -1.09158271043224 0.42096256684492 0.0095125176693262
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) rs8056750 -0.964683432542508 0.353337510561742 0.0063295173143327
Coffee Heel bone mineral density (BMD) (left) (ukb-b-1096) All - Inverse variance weighted 0.118552622894441 0.0583528682041567 0.0421890694497709
Coffee Operation code: knee replacement/revision (ukb-b-11120) rs1057868 0.0416972667899694 0.012675919382083 0.0010037034015684
Coffee Operation code: knee replacement/revision (ukb-b-11120) rs1421085 0.0273264806445698 0.0125544961332284 0.0295082579510267
Coffee Operation code: knee replacement/revision (ukb-b-11120) rs2472297 0.0279485182092841 0.0055749632026993 5.35265779301043e-07
Coffee Operation code: knee replacement/revision (ukb-b-11120) rs4410790 0.0172174191236691 0.0060599662162162 0.0044947765236344
Coffee Operation code: knee replacement/revision (ukb-b-11120) rs516636 0.0489021727029041 0.0240658747762638 0.042152330219456
Coffee Operation code: knee replacement/revision (ukb-b-11120) rs9398171 0.055112040303195 0.0232036250771342 0.0175419218920747
Coffee Operation code: knee replacement/revision (ukb-b-11120) All - Inverse variance weighted 0.0125131590328836 0.0021209097779937 3.63718383962318e-09
Coffee Operation code: knee replacement/revision (ukb-b-11120) All - MR Egger 0.031343871915802 0.0047237192443609 1.45085956007888e-09
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs10193706 -1.64959990772293 0.831876574508214 0.0473689521757746
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs10992783 -2.01892272695072 0.896251662822824 0.0242825341330308
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs11236225 -1.7950884760551 0.843356698201069 0.0332952822777691
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs12930957 1.72630588486363 0.857983846423405 0.044214729636188
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs13378244 1.82581827491198 0.871832535315156 0.0362394532053542
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs13387939 1.16766933642591 0.53785561555467 0.0299333093809963
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs1421085 1.41318908890878 0.372912644397226 0.0001508911486365
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs17842490 -1.40832840731221 0.633269350407255 0.0261550988041517
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs329122 1.53723869236054 0.783746031456202 0.0498324950802953
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs4840338 3.24482127881561 0.896996110593844 0.0002975419463167
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs4970968 2.81599124179388 0.879014751915544 0.0013573184601786
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) rs62121718 2.08384430833627 0.886660905032093 0.0187625387372096
Coffee Heel bone mineral density (BMD), manual entry (ukb-b-11364) All - Inverse variance weighted 0.149321085700979 0.0711212284847718 0.0357702892392035
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs10938398 -0.102077856803794 0.0352891275182063 0.0038204938695253
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs11206378 0.13627067502525 0.0345047187037984 7.83687824639728e-05
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs11678584 -0.0617034197502331 0.0302612430963443 0.0414475703030137
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs13378240 0.0676448719040702 0.0331508214760095 0.0412986881604372
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs13378244 -0.0913883741974404 0.0337485647079101 0.0067706577496381
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs13387939 -0.0657624518295703 0.0209742205148649 0.0017162325274537
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs1421085 -0.0457956812960426 0.0144134587382568 0.0014866033359818
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs144620429 -0.0715126139255322 0.0345222112313396 0.0383124909982934
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs1527961 -0.0656364712847839 0.0287915102187648 0.0226245278931543
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs2472297 -0.0144328911918882 0.0064005569088545 0.024136904905405
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs476828 -0.0457294723309562 0.0177653190054249 0.0100505068798072
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs4840338 -0.0837964301986965 0.0349144528747928 0.01639283563901
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs56113850 -0.0411623390464762 0.0209499711842864 0.0494382984725957
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs73123665 -0.122080248460875 0.0344148269516467 0.0003891782573347
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) rs780093 -0.0715522623838718 0.0202541843758228 0.0004113155137307
Coffee Non-cancer illness code, self-reported: osteoporosis (ukb-b-12141) All - Inverse variance weighted -0.0095552117009589 0.0031102492580686 0.0021250929288301
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs1057868 0.0782430867780401 0.0317626773729506 0.0137639487621635
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs117968677 -0.126185711201132 0.0630411312959436 0.045323359310209
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs13054099 -0.126413798862466 0.0604150236135725 0.0364006725400072
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs13387939 0.159310936348591 0.0457751362060426 0.0005008636476971
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs1421085 0.0676081024236083 0.0314583715336576 0.0316241657517125
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs2231142 0.241778718393457 0.0717112486673138 0.000747439796808
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs2472297 0.0750494934453463 0.013969890770118 7.77679859928337e-08
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs329122 0.179777601778455 0.0662748526132476 0.0066756308594052
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs35303290 0.183239940842561 0.0691787689510037 0.0080780822659771
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs4410790 0.0337996519246519 0.0151847870597871 0.0260216109956201
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs442355 0.137719534532917 0.0590322522716661 0.019650554875766
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs476828 0.0975533405203475 0.0387739030675483 0.011871081442478
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs4840338 0.154341409298916 0.0762022491200962 0.0428244576036499
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs4984636 -0.148669955563173 0.0750138941595564 0.0474905552374333
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs56791931 0.152964523630514 0.0722306925672722 0.0341986221710752
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs73123665 0.188531916584641 0.0751111165455135 0.0120717442816284
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs76852278 -0.159997062926793 0.0717383802041266 0.0257285009482675
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs7743687 -0.211671520811181 0.071981925275809 0.0032755563269239
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) rs8056750 0.140558989110725 0.0584960078987592 0.0162664470095862
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) All - Inverse variance weighted 0.0264461432033451 0.0068573438659116 0.0001149674749719
Coffee Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) All - MR Egger 0.0511564642485324 0.0147154337741861 0.0007160082445227
Coffee Diagnoses - main ICD10: T84.0 Mechanical complication of internal joint prosthesis (ukb-b-14753) rs12604773 0.0252973455844819 0.0128425913035408 0.0488612141483013
Coffee Diagnoses - main ICD10: T84.0 Mechanical complication of internal joint prosthesis (ukb-b-14753) rs1421085 0.012317204706999 0.0057566900003235 0.0323844261364643
Coffee Diagnoses - main ICD10: T84.0 Mechanical complication of internal joint prosthesis (ukb-b-14753) rs4410790 0.0058280354217854 0.0027786906224406 0.0359578720082992
Coffee Diagnoses - main ICD10: T84.0 Mechanical complication of internal joint prosthesis (ukb-b-14753) rs4840338 0.0308540185027437 0.0139442804598612 0.02692076405927
Coffee Diagnoses - main ICD10: T84.0 Mechanical complication of internal joint prosthesis (ukb-b-14753) rs9953004 -0.0286313747524337 0.0140249002743251 0.0412044048010028
Coffee Diagnoses - main ICD10: T84.0 Mechanical complication of internal joint prosthesis (ukb-b-14753) All - MR Egger 0.0099569743123553 0.0032956211297182 0.0037648314621753
Coffee Fracture resulting from simple fall (ukb-b-15251) rs10938398 1.02217337944588 0.430899660006409 0.0176832709157155
Coffee Fracture resulting from simple fall (ukb-b-15251) rs13378240 -0.824342024995338 0.404692898957415 0.0416543533508268
Coffee Fracture resulting from simple fall (ukb-b-15251) rs4984636 -0.972660945782174 0.418926660872333 0.0202440898841535
Coffee Fracture resulting from simple fall (ukb-b-15251) rs6969878 -1.07474282090262 0.363459583477117 0.0031066798606737
Coffee Fracture resulting from simple fall (ukb-b-15251) rs7743687 -1.38466991224608 0.404158798685173 0.0006124183722093
Coffee Fracture resulting from simple fall (ukb-b-15251) All - MR Egger -0.173969778679914 0.0625102363297495 0.0062965913520596
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs10938398 0.976760234711258 0.465204840487559 0.0357609861628289
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs11032480 -1.00039986895861 0.450135618207045 0.0262535148011944
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs11206378 -1.52192364943318 0.45473973458393 0.0008174971079273
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs11236225 -0.983834125778148 0.426108524091956 0.0209501529566208
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs12514566 0.890604709928755 0.321281542835082 0.0055706498738373
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs13054099 -1.07555415348358 0.366512335656031 0.0033401593504357
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs13378244 1.65685302862473 0.445100235983565 0.0001973171549805
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs13387939 0.915383128571256 0.275545126179345 0.0008934886809792
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs1421085 1.0645001240387 0.189704787893823 2.00753266684073e-08
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs1447365 1.18905414603291 0.442019033967238 0.0071440905537466
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs17842490 0.760801269917176 0.323961716513573 0.0188527650052052
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs2126069 -2.16746120135456 0.393670433349631 3.67545749612328e-08
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs2189234 -0.805821431897217 0.355929623736719 0.0235746740082617
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs2595223 -1.13173622311219 0.430833167219373 0.008617806924042
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs34060476 0.558635209341697 0.275303322987433 0.0424417305440379
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs4615895 1.1420364679369 0.32380823601721 0.0004204692615832
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs476828 0.681697903275088 0.233213229486743 0.0034660188707421
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs4840338 4.24407509393345 0.459591777438803 2.59627913652575e-20
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs516636 1.38681305505836 0.363783431962798 0.0001377386395433
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs55716899 -1.33720120971314 0.443407949181925 0.0025635655582689
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs56791931 0.956270872309548 0.435214099627577 0.028003139006713
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs57918684 1.19607493171095 0.371278246833871 0.001275189938816
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs6062682 0.762818213376533 0.339236673609504 0.0245359612634655
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs62121718 0.991712810983088 0.452214300923569 0.0283062878917439
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs6469262 -1.17406841339951 0.381755771308586 0.0021018954866402
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs6544966 1.03850098730318 0.443461546331632 0.0191906782651429
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs7585210 -1.30509368576203 0.467348010194273 0.0052294039128213
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs763030 -1.02364879540577 0.428362047245463 0.0168629963357297
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs76852278 0.948575519494823 0.431452382700639 0.0279089649969082
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs780093 0.558729454244556 0.266236882687027 0.0358506082190059
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs78308709 -1.18176500132951 0.421197151889385 0.0050202917726168
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) rs8056750 -0.972098012968395 0.353471371744847 0.0059568647986614
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) All - Inverse variance weighted 0.121303251074922 0.0582364945058062 0.0372564938412608
Coffee Neck/shoulder pain for 3+ months (ukb-b-16118) rs1421085 -0.286996429842633 0.110106457562586 0.0091463246652409
Coffee Neck/shoulder pain for 3+ months (ukb-b-16118) rs2472297 0.0975360871773242 0.0489229795914854 0.0461885536414001
Coffee Neck/shoulder pain for 3+ months (ukb-b-16118) rs2595223 -0.533033724154178 0.250722142688872 0.0335037746921632
Coffee Neck/shoulder pain for 3+ months (ukb-b-16118) rs4840338 0.587231654087178 0.26685552407932 0.0277671714808629
Coffee Neck/shoulder pain for 3+ months (ukb-b-16118) rs55780162 -0.522273513768907 0.26325077735425 0.0472626279409809
Coffee Neck/shoulder pain for 3+ months (ukb-b-16118) rs7590617 -0.551164602279851 0.267457029363824 0.0393259942611974
Coffee Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) rs13163336 0.0519001552130165 0.0200644267822736 0.0096906890350129
Coffee Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) rs13387939 0.0438895734425398 0.0175139226132232 0.0122111863218692
Coffee Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) rs1421085 0.0452468370131481 0.0120349896993949 0.0001701801703184
Coffee Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) rs2472297 0.0259976157070677 0.0053441300773819 1.14627710302124e-06
Coffee Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) rs476828 0.038723055903056 0.0148333631190873 0.0090399966931805
Coffee Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) rs6030315 0.0649578977782823 0.0289287667557555 0.024739705429119
Coffee Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) rs780093 0.0333103396396735 0.0169122503479144 0.0488844259302577
Coffee Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) rs9398171 0.0554865210864179 0.0222432927783969 0.0126124704324466
Coffee Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) All - Inverse variance weighted 0.0097833228150044 0.002334591806938 2.78227011744759e-05
Coffee Operative procedures - main OPCS: W40.1 Primary total prosthetic replacement of knee joint using cement (ukb-b-16240) All - MR Egger 0.029438177763215 0.0047535292120298 1.19532478861743e-08
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs11206378 -0.315927734694751 0.112067892916781 0.0048162344357734
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs12930957 -0.304244284953844 0.107697988017592 0.0047284084216534
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs13163336 0.187746199957183 0.0780661260971955 0.016174072003672
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs1338549 -0.305161984550126 0.0906015208634662 0.0007566692302522
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs13387939 0.224688628758502 0.068128994068544 0.0009738017450656
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs1421085 0.115037265539892 0.0468230453118764 0.014016064068419
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs2231142 0.219996658339035 0.106724694874529 0.0392699216305554
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs2472297 0.0935023713815988 0.0207936596744622 6.90237193148396e-06
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs2595223 -0.233970606889803 0.106559749681363 0.0281151946341151
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs2597805 -0.201005172998127 0.0941054406789636 0.0326829203986443
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs329122 0.249358071635782 0.0986404813150345 0.0114731130830024
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs34060476 0.160099190415211 0.068019772968984 0.0185868332430673
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs35303290 0.309962422720467 0.102955479241345 0.0026069324437103
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs4410790 0.0514550061425061 0.0225997389434889 0.0227983816523745
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs476828 0.199502481825886 0.057722485169577 0.0005477772369948
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs4840338 0.286968178186308 0.113419837952416 0.011401670883186
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs516636 0.257985560988978 0.089730831484923 0.0040389317581063
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs56791931 0.237857779798227 0.107503540643086 0.0269281584290613
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs6030315 0.364784019730257 0.112559206249291 0.0011918681434473
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs6469262 0.223001768728144 0.0939884000275305 0.0176608930317106
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs763030 -0.229402003457833 0.105715849558214 0.0300078420920901
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) rs9953004 -0.276782286584513 0.114096977339581 0.0152725317798349
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) All - Inverse variance weighted 0.0312097669066481 0.0107791022555203 0.0037868078277746
Coffee Pain type(s) experienced in last month: Knee pain (ukb-b-16254) All - MR Egger 0.101692069420864 0.0222976360646478 1.27309108448801e-05
Coffee Operative procedures - secondary OPCS: Z84.3 Hip joint (ukb-b-17133) rs13088645 -0.046425811512178 0.0204223307922444 0.0230089128001693
Coffee Operative procedures - secondary OPCS: Z84.3 Hip joint (ukb-b-17133) rs2465037 0.0322499694310411 0.0154432499035902 0.0367717700066445
Coffee Operative procedures - secondary OPCS: Z84.3 Hip joint (ukb-b-17133) rs2521501 0.0404296744236272 0.0180597159980563 0.0251776482478867
Coffee Operative procedures - secondary OPCS: Z84.3 Hip joint (ukb-b-17133) rs780093 0.0285516981983676 0.0119829992101403 0.0171869494208488
Coffee Operative procedures - secondary OPCS: Z84.3 Hip joint (ukb-b-17133) rs7811609 -0.0369256256948517 0.0175201124018454 0.0350644335272271
Coffee Operative procedures - secondary OPCS: Z84.3 Hip joint (ukb-b-17133) All - MR Egger 0.0080052221759319 0.0033070955312875 0.0174363608181721
Coffee Fractured heel (ukb-b-18389) rs11032480 -0.0391244074231095 0.0192806694673553 0.0424375384219656
Coffee Fractured heel (ukb-b-18389) rs117968677 0.0369978633511549 0.0163761082053116 0.0238673033491878
Coffee Fractured heel (ukb-b-18389) rs1421085 -0.0164253125235943 0.0081370465846213 0.0435304692499375
Coffee Fractured heel (ukb-b-18389) rs17842490 -0.0273649882771767 0.0137699891295444 0.0468900554143166
Coffee Fractured heel (ukb-b-18389) rs2577374 -0.0406217126331365 0.0174687696515522 0.0200510839899981
Coffee Fractured heel (ukb-b-18389) rs4615895 -0.0313423478795329 0.0139018233968449 0.0241616253158592
Coffee Fractured heel (ukb-b-18389) rs4877113 0.0440017119411607 0.0187190375526168 0.0187411734767006
Coffee Fractured heel (ukb-b-18389) rs4937720 -0.0504582438863285 0.0197772957230571 0.0107315216395551
Coffee Fractured heel (ukb-b-18389) rs56349356 -0.0421430392986632 0.0200852647568642 0.0358868802845325
Coffee Fractured heel (ukb-b-18389) rs6989976 -0.0512699803642643 0.0190425216582036 0.007094097849605
Coffee Fractured heel (ukb-b-18389) rs723145 0.0412789366049006 0.0187214909356317 0.027461407793094
Coffee Fractured heel (ukb-b-18389) rs7590617 -0.0436052917308036 0.0197255428185749 0.0270635249553309
Coffee Fractured heel (ukb-b-18389) All - Inverse variance weighted -0.002963474077201 0.0013797090028892 0.0317218668354496
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs10938398 1.09655312715654 0.463025530766295 0.0178731939262457
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs10992783 -1.59982578077239 0.458524541559419 0.0004846980374954
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs11032480 -0.90132751676559 0.448055576967548 0.0442576651647359
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs11206378 -1.59754632439798 0.4524729433277 0.0004144611845184
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs13054099 -0.92677472930217 0.364816240941945 0.0110729614193855
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs13163336 0.619139370584457 0.315313235923785 0.0495800676640437
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs13378244 1.58617202213328 0.443057241856539 0.0003435137999913
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs13387939 0.984410297297624 0.274130516193721 0.0003293765302596
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs1421085 1.12155792607293 0.188728117955411 2.8033498879707e-09
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs1447365 1.37532078031088 0.439741403568688 0.0017625953478653
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs17144566 0.798949294013826 0.397682563612296 0.0445357940610881
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs17842490 0.867446859855252 0.322305687838595 0.0071157239515969
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs2126069 -1.94757202875718 0.391825573604245 6.67778109968394e-07
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs2595223 -1.0415115766329 0.428592138883352 0.0150956467368626
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs4615895 1.25304650686335 0.322115140340094 0.0001002203573642
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs476828 0.836810579899805 0.232161696289079 0.0003128387643376
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs4840338 4.41545989421344 0.457497177043919 4.85184874217295e-22
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs516636 1.18855498556955 0.361946440347016 0.0010242232968468
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs55716899 -1.15910005441178 0.441247927923368 0.0086174760024038
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs56791931 0.882712919413215 0.433123808857727 0.0415484096740772
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs57918684 1.42835081946859 0.369557828408244 0.0001110771151457
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs6062682 0.669725372213222 0.337645606726838 0.0473098517564639
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs630194 0.723439880915681 0.31932565861908 0.0234805549496253
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs6544966 1.10048751291679 0.441196631914959 0.0126197159976136
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs75347775 0.864897037433974 0.383281979637143 0.0240358671972125
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs7585210 -1.41510852365436 0.465144509240408 0.0023477881134865
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs763030 -1.07955621584521 0.426349901390952 0.0113384964660913
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs78308709 -1.09522261943451 0.419114249416492 0.0089703013483409
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs8056750 -0.854526121918107 0.351771049908386 0.015131721058696
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) rs874573 1.00020941408543 0.437646142277883 0.0222876545543347
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-b-20032) All - Inverse variance weighted 0.119642976173426 0.0593829288784458 0.0439286963113765
Coffee Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) rs12604773 0.0595714418302473 0.0280818135412316 0.0338921000563343
Coffee Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) rs13387939 0.0411736068326508 0.0183187160994938 0.0246001031363604
Coffee Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) rs1421085 0.0381512301403255 0.0125873933536829 0.0024381959568163
Coffee Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) rs2472297 0.0164749907468776 0.005589488452964 0.0032035965885905
Coffee Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) rs4615895 -0.0450420815406679 0.021520426142184 0.0363498612840984
Coffee Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) rs476828 0.0660915133661169 0.015514496053868 2.04441042295789e-05
Coffee Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) rs4840338 0.0832657804895765 0.0304899066938727 0.006315601257191
Coffee Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) rs516636 0.0506746769207053 0.02412830679901 0.0357097682543808
Coffee Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) rs780093 0.0392055515853613 0.0176893970737579 0.026668870535591
Coffee Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) All - Inverse variance weighted 0.0089546066704846 0.0023383424648713 0.0001284207970131
Coffee Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) All - MR Egger 0.0182226753337679 0.0051338571911797 0.000578895156516
Coffee Ankle spacing width (left) (ukb-b-2122) rs10053913 0.936836336397424 0.387242103046301 0.0155524502237658
Coffee Ankle spacing width (left) (ukb-b-2122) rs10193706 0.77976702493567 0.380393821853714 0.0403747727948137
Coffee Ankle spacing width (left) (ukb-b-2122) rs10500356 0.802719515062174 0.397028866254503 0.0431953119336323
Coffee Ankle spacing width (left) (ukb-b-2122) rs1057868 0.51863825692074 0.170858457513195 0.0024014929902016
Coffee Ankle spacing width (left) (ukb-b-2122) rs10938398 1.47308838370743 0.415165815020616 0.0003878840796073
Coffee Ankle spacing width (left) (ukb-b-2122) rs10992783 0.816815304004681 0.411518147398912 0.0471575093796328
Coffee Ankle spacing width (left) (ukb-b-2122) rs11032480 0.793443594388345 0.402482559932167 0.048681129683279
Coffee Ankle spacing width (left) (ukb-b-2122) rs11206378 -0.960959557925332 0.406078022955039 0.0179600515570692
Coffee Ankle spacing width (left) (ukb-b-2122) rs11236225 1.11027890789667 0.380998970638694 0.0035668620664103
Coffee Ankle spacing width (left) (ukb-b-2122) rs13163336 0.982110361806893 0.282559275315778 0.0005093935878459
Coffee Ankle spacing width (left) (ukb-b-2122) rs1338549 -0.656652428630831 0.327951659099734 0.0452541732592172
Coffee Ankle spacing width (left) (ukb-b-2122) rs13387939 2.34117348602907 0.246175962502567 1.90364344076015e-21
Coffee Ankle spacing width (left) (ukb-b-2122) rs1421085 1.72358245337763 0.169576003365224 2.86844857690314e-24
Coffee Ankle spacing width (left) (ukb-b-2122) rs17144566 -1.01519524930137 0.357321848801294 0.0044954998926914
Coffee Ankle spacing width (left) (ukb-b-2122) rs2189234 2.10605103290414 0.317617396406689 3.3391794010232e-11
Coffee Ankle spacing width (left) (ukb-b-2122) rs2231142 1.09017710803113 0.388733033114269 0.0050404614670159
Coffee Ankle spacing width (left) (ukb-b-2122) rs2350804 0.79603381363557 0.390043016817293 0.0412620370300642
Coffee Ankle spacing width (left) (ukb-b-2122) rs2521501 1.43413422601371 0.360111225095837 6.82010816892259e-05
Coffee Ankle spacing width (left) (ukb-b-2122) rs2577374 0.853486163563683 0.3647758168362 0.0192963763264273
Coffee Ankle spacing width (left) (ukb-b-2122) rs2597805 0.700947334454928 0.340239796570682 0.0393835521919573
Coffee Ankle spacing width (left) (ukb-b-2122) rs329122 1.03246959256664 0.356954395126594 0.0038226074908311
Coffee Ankle spacing width (left) (ukb-b-2122) rs4410790 0.262361793611794 0.081735002047502 0.0013277770706475
Coffee Ankle spacing width (left) (ukb-b-2122) rs476828 2.11848196424557 0.208401312110503 2.82968405996246e-24
Coffee Ankle spacing width (left) (ukb-b-2122) rs4840338 1.55510212167436 0.410718648678989 0.0001529098992208
Coffee Ankle spacing width (left) (ukb-b-2122) rs4937720 1.42583529741442 0.411905333793704 0.0005370530845824
Coffee Ankle spacing width (left) (ukb-b-2122) rs4984636 1.18571655914505 0.406126895910098 0.0035051284254297
Coffee Ankle spacing width (left) (ukb-b-2122) rs516636 2.43883117661668 0.324855481428828 6.0297438761134e-14
Coffee Ankle spacing width (left) (ukb-b-2122) rs55716899 1.29772103205234 0.395712857630936 0.0010400917238606
Coffee Ankle spacing width (left) (ukb-b-2122) rs56791931 1.00469463046177 0.389035371461542 0.0098079483028458
Coffee Ankle spacing width (left) (ukb-b-2122) rs6062682 -1.38046748437862 0.303242883591761 5.30501967565644e-06
Coffee Ankle spacing width (left) (ukb-b-2122) rs6063085 1.15961616045185 0.307145601598371 0.0001597121788649
Coffee Ankle spacing width (left) (ukb-b-2122) rs62064918 1.85092408440456 0.349648314334223 1.19883265239176e-07
Coffee Ankle spacing width (left) (ukb-b-2122) rs6691876 1.34140831174161 0.357357085324247 0.0001742491847162
Coffee Ankle spacing width (left) (ukb-b-2122) rs6937318 0.899110626820991 0.36197653127986 0.0129955197807526
Coffee Ankle spacing width (left) (ukb-b-2122) rs730632 1.06525422115623 0.385848894980298 0.0057658788550376
Coffee Ankle spacing width (left) (ukb-b-2122) rs73123665 0.808158124805126 0.403992859195315 0.0454542016099797
Coffee Ankle spacing width (left) (ukb-b-2122) rs7590617 1.34472814386593 0.411022838529648 0.001069170000706
Coffee Ankle spacing width (left) (ukb-b-2122) rs9398171 2.0037669119611 0.312971439623493 1.52957896577839e-10
Coffee Ankle spacing width (left) (ukb-b-2122) rs9650210 0.770391149000188 0.382669403873879 0.0440932895582679
Coffee Ankle spacing width (left) (ukb-b-2122) All - Inverse variance weighted 0.352038315421423 0.0652728802176681 6.91629797936861e-08
Coffee Ankle spacing width (ukb-b-4080) rs10500356 0.575671777406421 0.289933346464948 0.0470853747923853
Coffee Ankle spacing width (ukb-b-4080) rs10938398 1.88937775987171 0.303216576050463 4.63123018826763e-10
Coffee Ankle spacing width (ukb-b-4080) rs11032480 0.826022074693594 0.294629952593849 0.0050536866804989
Coffee Ankle spacing width (ukb-b-4080) rs11206378 -1.34777111453089 0.295733143258689 5.17933291364487e-06
Coffee Ankle spacing width (ukb-b-4080) rs11236225 1.16844272339591 0.280873486593794 3.18202853618923e-05
Coffee Ankle spacing width (ukb-b-4080) rs12514566 0.495819148562805 0.20892061208016 0.0176327120680671
Coffee Ankle spacing width (ukb-b-4080) rs12604773 -0.684420390737389 0.27777739106223 0.0137427993780861
Coffee Ankle spacing width (ukb-b-4080) rs13163336 0.943775422821665 0.207011346606722 5.13851318919902e-06
Coffee Ankle spacing width (ukb-b-4080) rs13387939 2.1821778470385 0.180164051269042 9.10515247925635e-34
Coffee Ankle spacing width (ukb-b-4080) rs1421085 1.97802897112595 0.124385469135936 6.09713634438907e-57
Coffee Ankle spacing width (ukb-b-4080) rs16930598 -0.762843970532456 0.300354187478965 0.0110911224405195
Coffee Ankle spacing width (ukb-b-4080) rs2189234 1.74034158782163 0.232492798058254 7.123617165352862e-14
Coffee Ankle spacing width (ukb-b-4080) rs2231142 1.39904205719014 0.282201677195551 7.13705824156672e-07
Coffee Ankle spacing width (ukb-b-4080) rs2372891 0.672530344910468 0.290946314831665 0.0208037479091702
Coffee Ankle spacing width (ukb-b-4080) rs2465037 0.513617765738311 0.223969826086139 0.0218338826859582
Coffee Ankle spacing width (ukb-b-4080) rs2472297 -0.130643328713945 0.0551307487712714 0.0178025295440844
Coffee Ankle spacing width (ukb-b-4080) rs2521501 2.10632255277793 0.26327520112305 1.23955879293725e-15
Coffee Ankle spacing width (ukb-b-4080) rs2597805 0.701257836107892 0.24932572435165 0.0049140102753753
Coffee Ankle spacing width (ukb-b-4080) rs329122 0.706307217214864 0.261186671627109 0.0068464157624765
Coffee Ankle spacing width (ukb-b-4080) rs4410790 0.155732493857494 0.0598843161343161 0.0093072934666644
Coffee Ankle spacing width (ukb-b-4080) rs442355 -0.493123047085443 0.232849369679991 0.0341939553646614
Coffee Ankle spacing width (ukb-b-4080) rs476828 2.35391240682344 0.153598215160757 5.19515914574325e-53
Coffee Ankle spacing width (ukb-b-4080) rs4840338 1.34589301161539 0.300966078303189 7.7524300708117e-06
Coffee Ankle spacing width (ukb-b-4080) rs4877113 0.609648965475441 0.286031475473103 0.03305577736323
Coffee Ankle spacing width (ukb-b-4080) rs4984636 0.595348210897428 0.295828079668009 0.0441693211792518
Coffee Ankle spacing width (ukb-b-4080) rs516636 2.36616509801571 0.236971918435859 1.77297367241963e-23
Coffee Ankle spacing width (ukb-b-4080) rs55716899 0.568600604856568 0.288950611816215 0.0490896237506535
Coffee Ankle spacing width (ukb-b-4080) rs56349356 1.1082385639153 0.305298833199664 0.0002834075552843
Coffee Ankle spacing width (ukb-b-4080) rs56791931 1.02812407112759 0.28588900739601 0.0003228560861678
Coffee Ankle spacing width (ukb-b-4080) rs6062682 -1.1290596312582 0.221695402298851 3.52735851491207e-07
Coffee Ankle spacing width (ukb-b-4080) rs6063085 1.48784892321288 0.22502449426546 3.79310414089118e-11
Coffee Ankle spacing width (ukb-b-4080) rs62064918 1.63503274314819 0.255295658501091 1.50895109175892e-10
Coffee Ankle spacing width (ukb-b-4080) rs641727 0.613557951856185 0.260276500054925 0.0184068144960859
Coffee Ankle spacing width (ukb-b-4080) rs6544966 1.29885360288927 0.289706980693875 7.34852415701702e-06
Coffee Ankle spacing width (ukb-b-4080) rs6691876 1.37512196506178 0.262034431801067 1.53869938252325e-07
Coffee Ankle spacing width (ukb-b-4080) rs6937318 1.4055108659327 0.264380827759552 1.05935753671953e-07
Coffee Ankle spacing width (ukb-b-4080) rs7743687 -0.558125861625469 0.283275782975288 0.0488090179711316
Coffee Ankle spacing width (ukb-b-4080) rs8068193 -0.673320310512079 0.301859340481531 0.0257092038131999
Coffee Ankle spacing width (ukb-b-4080) rs9398171 2.36032493069435 0.228712342392956 5.718784066207241e-25
Coffee Ankle spacing width (ukb-b-4080) All - Inverse variance weighted 0.332733223052767 0.0664108177542368 5.43660790538619e-07
Coffee Non-cancer illness code, self-reported: joint pain (ukb-b-4122) rs11206378 -0.0356393736603893 0.0158282477451724 0.024345598907519
Coffee Non-cancer illness code, self-reported: joint pain (ukb-b-4122) rs6063085 -0.0286380227844697 0.0119538739361804 0.0165881806632892
Coffee Non-cancer illness code, self-reported: joint pain (ukb-b-4122) rs641727 -0.037224057189844 0.0138452661923598 0.0071757393640779
Coffee Non-cancer illness code, self-reported: joint pain (ukb-b-4122) rs780093 0.0194492044984391 0.0092913830067326 0.0363266800437944
Coffee Non-cancer illness code, self-reported: joint pain (ukb-b-4122) All - Inverse variance weighted -0.0027161559949249 0.0012440906847791 0.0290176998365993
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs10938398 1.05949156531347 0.463092013674204 0.0221454400216503
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs10992783 -1.57403398849209 0.458524541559419 0.0005973300098649
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs11032480 -0.934658762429662 0.448130251291143 0.0370071217146888
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs11206378 -1.63468392114589 0.452515760495873 0.0003033347690929
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs13054099 -0.961216214962376 0.364849643244848 0.0084247814673547
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs13163336 0.709269963605224 0.315417603296939 0.0245335271469672
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs13378244 1.58506941364041 0.443115540696392 0.0003474248501356
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs13387939 1.01053407265128 0.274156488964592 0.0002278283636392
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs1421085 1.14133940224133 0.188762093773257 1.48077799890792e-09
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs1447365 1.41821575196677 0.43978108773086 0.0012605098986002
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs17144566 0.788280445653773 0.397741395793499 0.0474913421066995
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs17842490 0.801900890668898 0.322549221467268 0.0129138986763659
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs2126069 -2.00137855163796 0.391864055341265 3.26745010806783e-07
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs2595223 -0.96962711946312 0.428656168264381 0.0236964135700207
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs4615895 1.20058184798197 0.322128252407294 0.0001937489574353
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs476828 0.818581698479774 0.232181873735306 0.000422515797945
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs4840338 4.41774467270218 0.457594907453264 4.715065373816869e-22
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs516636 1.13480692318891 0.361990973477095 0.0017191040380928
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs55716899 -1.11486960152859 0.441304870487302 0.0115270177381906
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs56791931 0.896700645183851 0.433167520500761 0.0384428596424382
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs57918684 1.40856251552024 0.369589644896946 0.0001383203738711
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs6062682 0.745761012111394 0.337684178045206 0.0272124269194312
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs630194 0.704567834902627 0.319374102683801 0.0273777380520991
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs6544966 1.06556102352135 0.441277201993022 0.0157472963610558
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs7224815 0.657411465718863 0.321692049870168 0.0409925898101308
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs75347775 0.858665697006813 0.383323126387507 0.0250872151054616
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs7585210 -1.40927935166791 0.465208593160767 0.0024508109623169
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs763030 -1.08205836613062 0.426402898324081 0.0111601736803974
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs780093 0.53137172302253 0.264845977357355 0.0448197255135643
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs78308709 -1.09620941294649 0.419127839985818 0.0089109030748971
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs8056750 -0.868722052917889 0.351796682900895 0.0135344867510477
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) rs874573 1.04492854422489 0.437707989961144 0.0169738733109523
Coffee Heel bone mineral density (BMD) (right) (ukb-b-4657) All - Inverse variance weighted 0.117961838796697 0.0597066670402745 0.0481899479472468
Coffee Operative procedures - main OPCS: W85.2 Endoscopic irrigation of knee joint (ukb-b-4944) rs2126069 -0.0311637556364427 0.0154525678636751 0.0437230322051225
Coffee Operative procedures - main OPCS: W85.2 Endoscopic irrigation of knee joint (ukb-b-4944) rs2350804 0.0437035868236937 0.0172264224421556 0.011180411595575
Coffee Operative procedures - main OPCS: W85.2 Endoscopic irrigation of knee joint (ukb-b-4944) rs476828 0.0282388548434518 0.009180565083794 0.0020984102630523
Coffee Operative procedures - main OPCS: W85.2 Endoscopic irrigation of knee joint (ukb-b-4944) rs9296406 0.0356375352624766 0.0175333800921079 0.0420976408354039
Coffee Operative procedures - main OPCS: W85.2 Endoscopic irrigation of knee joint (ukb-b-4944) All - Inverse variance weighted 0.0039395618096749 0.001429469572488 0.0058520047079277
Coffee Operative procedures - main OPCS: W85.2 Endoscopic irrigation of knee joint (ukb-b-4944) All - MR Egger 0.0075720437033654 0.0030166779517703 0.0139894515518837
Coffee Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) rs10938398 0.0382337884753209 0.0188163914939108 0.0421596769590386
Coffee Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) rs2372891 -0.0362307286212165 0.0179929867632668 0.0440512516843235
Coffee Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) rs2472297 0.0076805004432891 0.0034125945755183 0.0244087455230745
Coffee Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) rs4615895 -0.02620045072731 0.013139192788363 0.0461445668384213
Coffee Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) rs71429826 0.0431580155425124 0.0186304663846717 0.0205294032742876
Coffee Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) rs723145 0.0587085425652228 0.0177309202402778 0.0009293575147964
Coffee Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) rs730632 0.039273789808311 0.0175398321055337 0.0251481057748887
Coffee Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) rs8056750 0.0292561685321789 0.0142901085130016 0.0406284362123266
Coffee Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) All - Inverse variance weighted 0.0035896233687944 0.0014596734690949 0.0139248516258383
Coffee Operative procedures - main OPCS: T72.3 Release of constriction of sheath of tendon (ukb-b-5534) All - MR Egger 0.0070562422852178 0.0030929664644491 0.0250257595128674
Coffee Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint (ukb-b-6725) rs13088645 -0.0387866762478923 0.0147321664707848 0.0084687102638733
Coffee Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint (ukb-b-6725) rs2465037 0.0264993368887384 0.0111404573116247 0.017375792945351
Coffee Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint (ukb-b-6725) rs6544966 -0.0425773216971384 0.0143958267257343 0.0031002847617208
Coffee Operative procedures - main OPCS: W58.1 Primary resurfacing arthroplasty of joint (ukb-b-6725) All - MR Egger 0.0052713326129523 0.0025745409795556 0.0445343021805435
Coffee Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) rs10938398 0.0555872900635975 0.0191038635877102 0.003617286892754
Coffee Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) rs11236225 0.0371549433851282 0.0176154110092643 0.0349247824685729
Coffee Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) rs12649199 -0.0392507919671565 0.0186594091380462 0.0354186932911127
Coffee Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) rs17144566 0.0323691903221062 0.0164157412854832 0.048628048198238
Coffee Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) rs442355 0.0343943720145099 0.0146416514025069 0.0188199955623572
Coffee Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) rs55780162 -0.0396309562574623 0.0186596944215654 0.0336801591503306
Coffee Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) rs61928609 0.0269535996741455 0.0130085876243169 0.0382668311616693
Coffee Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) rs71429826 0.0404581871440907 0.0189149752434666 0.0324397143716418
Coffee Operative procedures - main OPCS: A52.1 Therapeutic lumbar epidural injection (ukb-b-6798) rs7585210 -0.0451087947786393 0.0192034861652675 0.0188244181292249
Coffee Ankle spacing width (right) (ukb-b-8607) rs10053913 0.830086561956295 0.391945932880381 0.0341869372161685
Coffee Ankle spacing width (right) (ukb-b-8607) rs1057868 0.430137487531891 0.172942574019217 0.0128764049673311
Coffee Ankle spacing width (right) (ukb-b-8607) rs10938398 1.61671805795448 0.420331536965162 0.0001199185726772
Coffee Ankle spacing width (right) (ukb-b-8607) rs11236225 0.867831969021126 0.385636978579481 0.0244244675178114
Coffee Ankle spacing width (right) (ukb-b-8607) rs13163336 1.03339086919289 0.286074983943481 0.000303484141476
Coffee Ankle spacing width (right) (ukb-b-8607) rs1338549 -0.751761943708795 0.331927869553211 0.0235227906122014
Coffee Ankle spacing width (right) (ukb-b-8607) rs13387939 2.39580086736974 0.249288466881697 7.21580085073578e-22
Coffee Ankle spacing width (right) (ukb-b-8607) rs1421085 1.59830875928942 0.171571408540334 1.21144422647456e-20
Coffee Ankle spacing width (right) (ukb-b-8607) rs17144566 -0.856446720105898 0.361690138255626 0.0178892846501502
Coffee Ankle spacing width (right) (ukb-b-8607) rs2189234 2.12831021469146 0.321421383433682 3.5543339093724497e-11
Coffee Ankle spacing width (right) (ukb-b-8607) rs2231142 1.10724344795761 0.393444775074392 0.0048894479723341
Coffee Ankle spacing width (right) (ukb-b-8607) rs2350804 0.936317429196825 0.394813586331306 0.0177139814461048
Coffee Ankle spacing width (right) (ukb-b-8607) rs2521501 1.33980886561201 0.364445764267588 0.0002366490999629
Coffee Ankle spacing width (right) (ukb-b-8607) rs329122 0.9631162226995 0.361264730116198 0.0076769519986064
Coffee Ankle spacing width (right) (ukb-b-8607) rs4410790 0.231401771089271 0.0827375102375102 0.0051608570381428
Coffee Ankle spacing width (right) (ukb-b-8607) rs476828 2.06737537544462 0.210976530747546 1.13618526596494e-22
Coffee Ankle spacing width (right) (ukb-b-8607) rs4840338 1.50835000693358 0.415873267431341 0.0002867929135408
Coffee Ankle spacing width (right) (ukb-b-8607) rs4937720 1.22909567201597 0.417013195622476 0.0032048080234652
Coffee Ankle spacing width (right) (ukb-b-8607) rs4984636 1.09745987831899 0.411001481227583 0.0075804033457137
Coffee Ankle spacing width (right) (ukb-b-8607) rs516636 2.26868036345885 0.328740140621922 5.158837494221199e-12
Coffee Ankle spacing width (right) (ukb-b-8607) rs55716899 1.31381679679097 0.400561833297481 0.0010383098716929
Coffee Ankle spacing width (right) (ukb-b-8607) rs6062682 -1.297944148731 0.306991051454139 2.35825631385242e-05
Coffee Ankle spacing width (right) (ukb-b-8607) rs6063085 1.24952452308224 0.311023380016522 5.88283881041628e-05
Coffee Ankle spacing width (right) (ukb-b-8607) rs62064918 1.98637885035169 0.354035411108416 2.01534935172221e-08
Coffee Ankle spacing width (right) (ukb-b-8607) rs6691876 1.14917827744951 0.361731456399264 0.0014886741599718
Coffee Ankle spacing width (right) (ukb-b-8607) rs6937318 1.08112264830339 0.366309254282124 0.0031634390799037
Coffee Ankle spacing width (right) (ukb-b-8607) rs7224815 0.691320601830537 0.292479880665181 0.0180958105888177
Coffee Ankle spacing width (right) (ukb-b-8607) rs730632 0.982867911598424 0.390749624045838 0.0118917854160577
Coffee Ankle spacing width (right) (ukb-b-8607) rs73123665 1.20884408224153 0.408937621891946 0.0031159662733139
Coffee Ankle spacing width (right) (ukb-b-8607) rs73228435 -0.759686857504349 0.372119526285922 0.0411998611686932
Coffee Ankle spacing width (right) (ukb-b-8607) rs7590617 1.89656368297635 0.416256946130308 5.20791361085689e-06
Coffee Ankle spacing width (right) (ukb-b-8607) rs9398171 2.01875166932223 0.316746640632915 1.84888061691962e-10
Coffee Ankle spacing width (right) (ukb-b-8607) rs9650210 0.814306086629474 0.387180310913308 0.0354508954296552
Coffee Ankle spacing width (right) (ukb-b-8607) All - Inverse variance weighted 0.347297032788683 0.064167555520648 6.22042355606045e-08
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs1057868 0.0297926910565438 0.0121547398864212 0.0142413605628959
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs11206378 -0.0916652604165355 0.0288187247032392 0.0014689254273782
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs13054099 -0.0552019447563024 0.0231169915659185 0.0169431955601423
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs144620429 0.0640924089917166 0.0288332968368911 0.0262251790712221
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs2372891 -0.0830045968032688 0.028184498772469 0.0032290844987192
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs2472297 0.014551417234048 0.0053457009562994 0.0064872745438317
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs34276507 0.0682826344745454 0.0295324881544326 0.020771112400007
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs35303290 0.0572366457093765 0.0264728402179437 0.030611290326076
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs516636 0.0461659544220542 0.0230757833977065 0.0454329797072155
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs6937318 -0.160388415320094 0.0257222773978245 4.50655714397979e-10
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs71429826 -0.0572929577772677 0.0291829797466417 0.0496192303014891
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) rs7224815 0.0628835564722565 0.0205218135945931 0.0021823107643977
Coffee Non-cancer illness code, self-reported: rheumatoid arthritis (ukb-b-9125) All - MR Egger 0.0137471086355015 0.0059256300596155 0.0222974714340439
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs1057868 0.0490575863745495 0.0231834152845235 0.0343393798199007
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs12514566 0.0766057452707683 0.038797950373776 0.0483272824443743
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs12930957 -0.123237408588969 0.0528631311165514 0.0197399475911353
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs1338549 -0.100357837779501 0.044462137652216 0.0239985295893156
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs13387939 0.0738635402698752 0.0334634387948634 0.0272937502985439
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs1421085 0.0920199971956468 0.0229953188873189 6.28932869324866e-05
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs2372891 0.107975518052432 0.0538290598657442 0.0448673011411987
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs2472297 0.0364665553422795 0.0101591106673438 0.0003312593431685
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs2521501 0.152845958641542 0.0486846282598132 0.0016922967313749
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs2595223 -0.179764299391721 0.0523667313000985 0.0005973916645189
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs34276507 -0.112225617979815 0.0563735768778596 0.046508535240663
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs476828 0.0787779385567937 0.0283110901009449 0.0053928183771821
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs4840338 0.115969677159479 0.055634092064687 0.0371140369020445
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs516636 0.118531776957531 0.0438237687017736 0.0068358448292391
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs56212739 -0.105641366845547 0.0536106837169062 0.0487778604307267
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs56791931 0.111529382966447 0.0527005927298795 0.0343207223507598
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs6937318 0.138717739923654 0.0491467524581908 0.0047647704319274
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs75347775 0.128963484651305 0.0465188892291204 0.0055664770528779
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs77350503 -0.139366659606016 0.0565225285199867 0.0136752152075753
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) rs780093 0.098434573287697 0.0323454319780344 0.0023405374616626
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) All - Inverse variance weighted 0.0219620787704716 0.0048248499714275 5.31717680469329e-06
Coffee Gonarthrosis [arthrosis of knee](FG) (ukb-d-KNEE_ARTHROSIS) All - MR Egger 0.0426672166741597 0.0103198497786955 6.82523682463576e-05
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs12649199 -0.0364259907284204 0.0168718599508483 0.0308517989161518
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs2400677 -0.0367468774291356 0.0157352465467046 0.0195265725783149
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs2577374 0.0413500623618943 0.0151868938894643 0.0064741712511916
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs329122 0.0495888234851061 0.0148975311149811 0.0008726470537331
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs4410790 -0.0079335329647829 0.0034213503276003 0.0204042053641779
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs4937720 0.0433227498135999 0.0171640670739946 0.0116015535471479
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs630194 -0.0259758836637806 0.0119301876987308 0.029456403830186
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs723145 -0.033659451750524 0.0162879709435311 0.0387792088335695
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs730632 0.0329920240610664 0.016191156035254 0.0415842372630028
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs73075167 0.027293745603496 0.0120923935034456 0.0240018050557623
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs763030 0.0378590976620533 0.0159809211040738 0.0178353615526894
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs78267637 -0.0267684526408111 0.0133596844162842 0.0451049905391802
Coffee Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) rs874573 0.0330864489555879 0.0164495306628878 0.0442841024870369
Coffee Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) rs12649199 -0.087965650644228 0.0391073145092171 0.024490866551177
Coffee Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) rs13387939 0.0530525858007466 0.0238715133065149 0.026254773184899
Coffee Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) rs4840338 0.081759411504454 0.0396871306219748 0.0393890933695379
Coffee Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) rs4970968 0.113370168237223 0.038869424816838 0.0035376410444328
Coffee Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) rs730632 0.127539832105534 0.0375291721394171 0.0006777665880855
Coffee Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) rs78308709 -0.07729606759831 0.0360340355127485 0.0319460547795052
Coffee Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) rs7989746 0.0941250571997148 0.0398560961593717 0.0181951548447962
Coffee Disorders of synovium and tendon (ukb-d-M13_SYNOTEND) All - Inverse variance weighted 0.0071266900414059 0.002979348289645 0.0167554796133103
Coffee Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs13054099 -52.0983141115451 24.1609990999935 0.0310604031076423
Coffee Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs1338549 19.2144709513385 9.15861566931641 0.0359080846067863
Coffee Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs144620429 41.9306366238022 20.4027697024156 0.0398650655494412
Coffee Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs1527961 -14.1046683304479 5.64111788115206 0.0124076918678902
Coffee Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs2373834 52.0707452030534 23.3243572166481 0.025584432596352
Coffee Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs4984636 86.3886202548691 32.2075187601758 0.0073128766692704
Coffee Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs516636 25.6579341766081 10.7478996634323 0.0169748975791059
Coffee Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs55895231 58.780872395504 25.2207128582631 0.0197713666005393
Coffee Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs7224815 35.9753964015396 13.9408114031049 0.0098634145260489
Coffee Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) rs780093 16.6171437168541 8.32737804190018 0.0459901950552615
Coffee Neck/shoulder pain for 3+ months (ukb-e-3404_AFR) All - Inverse variance weighted 2.07793487532826 0.779617564131189 0.0076913748434972
Coffee Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs1057868 -4.82634868602419 2.0149466941341 0.0166079658242848
Coffee Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs11236225 10.3818440272536 4.57624626243812 0.0232903772494867
Coffee Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs2126069 11.6011118958367 5.72359247387769 0.0426733141090936
Coffee Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs4410790 -2.7257371007371 0.995085995085995 0.0061589357170047
Coffee Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs476828 -7.1947008261223 2.83810193645834 0.0112434611935884
Coffee Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) rs9953004 14.072188930895 6.55939429841176 0.031924966493277
Coffee Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) All - MR Egger -2.76816869281737 0.960171833538224 0.004778774013726
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs1057868 -4.5471632858668 1.9994085479853 0.0229507072197086
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs11236225 10.4308612322925 4.54487525121318 0.0217284273088281
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs4410790 -2.63615888615889 0.9876638001638 0.0076058141681182
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs476828 -7.49448002721073 2.81677149330397 0.00779869416855
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs630194 -21.8702932187117 10.5167660503994 0.0375654969629512
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) rs9953004 13.4620127170893 6.51490228282176 0.038796248917621
Coffee Heel bone mineral density (BMD) T-score, automated (left) (ukb-e-4106_EAS) All - MR Egger -2.68352946239709 0.940520593009071 0.0052137162000199
Coffee Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs2372891 16.3849640324824 7.50682438580528 0.0290596922067893
Coffee Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs2597805 9.69150747537803 4.64534825905985 0.0369530663301623
Coffee Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs4410790 -2.53122440622441 0.970260032760033 0.0090857583972662
Coffee Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs476828 -6.7623269783986 2.7625806377226 0.0143719561065058
Coffee Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs4938000 -10.0496036599554 4.81956176473045 0.0370539086388016
Coffee Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs4970968 -12.4095463444636 4.65718111524331 0.0077078885245035
Coffee Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs630194 -20.3905472417711 10.3229897915144 0.0482391068487674
Coffee Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs7743687 -15.8485743988032 7.9871125130244 0.0472259348666907
Coffee Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) rs9953004 16.1442456569437 6.39032463916975 0.0115252078444855
Coffee Heel bone mineral density (BMD) (right) (ukb-e-4124_EAS) All - MR Egger -2.59829778527731 0.990987863333641 0.0100424102498958
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) rs2372891 16.9751231823098 7.53794186825073 0.0243249708288166
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) rs2597805 9.32519670178244 4.66462777345962 0.045594304298813
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) rs4410790 -2.45981777231777 0.973843161343161 0.0115406597980989
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) rs476828 -7.12552101048651 2.77180461314071 0.0101488669811573
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) rs4938000 -9.56872141405632 4.83865386382322 0.0479785270036807
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) rs4970968 -12.239192220829 4.67597017299712 0.0088585353105226
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) rs630194 -21.8086371363392 10.3582218385844 0.0352528356766658
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) rs9953004 15.978989599038 6.41701984852376 0.0127708922863474
Coffee Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_EAS) All - MR Egger -2.50130845393945 0.983893388261081 0.0124733693177433