ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| White fish | Osteoporosis (bbj-a-137) | All - Inverse variance weighted | 1.93428364543299 | 0.979906712280609 | 0.0483878010187412 |
| White fish | Total body bone mineral density (age 15-30) (ebi-a-GCST005344) | rs10089529 | -4.76316485842816 | 2.29820891951556 | 0.0382136935485458 |
| White fish | Total body bone mineral density (age 15-30) (ebi-a-GCST005344) | All - Inverse variance weighted | -1.89903524057003 | 0.882921078192277 | 0.0314876441123882 |
| White fish | Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) (ebi-a-GCST005528) | rs10089529 | -9.17438475787245 | 4.63592963275781 | 0.0478189203224225 |
| White fish | Sciatica (ebi-a-GCST90038692) | rs151062788 | 0.0431833631579505 | 0.0170401414639828 | 0.0112699918288427 |
| White fish | Sciatica (ebi-a-GCST90038692) | All - Inverse variance weighted | 0.019273977469991 | 0.0078070417032608 | 0.0135569248666712 |
| White fish | Benign neoplasm: Scapula and long bones of upper limb (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER) | rs138602679 | -8.94677632360442 | 4.41609078141049 | 0.042769973554257 |
| White fish | Benign neoplasm: Scapula and long bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SCAPULA_LONG_UPPER_EXALLC) | rs138602679 | -8.9677387798453 | 4.41888577557594 | 0.042416367821228 |
| White fish | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | All - Inverse variance weighted | -2.7143602349984 | 1.31737769413927 | 0.0393577622348062 |
| White fish | Juvenile arthritis (FINNGEN) (finn-b-JUVEN_ARTHR) | All - Inverse variance weighted | 3.20876392397093 | 1.42514701909654 | 0.0243518710949179 |
| White fish | Achilles tendinitis (finn-b-M13_ACHILLESTEND) | All - Inverse variance weighted | -2.06617106142127 | 1.01084932474334 | 0.0409540317294169 |
| White fish | Loose body in joint (finn-b-M13_LOOSEJOINT) | rs138602679 | 6.19230957355377 | 2.6384744921845 | 0.0189289139122778 |
| White fish | Loose body in joint (finn-b-M13_LOOSEJOINT) | All - Inverse variance weighted | 4.25954869096335 | 2.10479454962231 | 0.0429973131758932 |
| White fish | Other osteochondropathies (finn-b-M13_OSTEOCHONDROPATHY) | rs138602679 | 3.10803351198004 | 1.47296192519198 | 0.0348534528584482 |
| White fish | Other osteochondropathies (finn-b-M13_OSTEOCHONDROPATHY) | All - Inverse variance weighted | 2.51529560840146 | 1.17363212273213 | 0.0320992825734931 |
| White fish | Otherdisorders of bone (finn-b-M13_OTHERBONE) | All - Inverse variance weighted | 1.4711921852899 | 0.689545739342069 | 0.0328782237849912 |
| White fish | Villonodular synovitis (pigmented) (finn-b-M13_VILLONODULAR) | rs11098631 | -26.0570041584123 | 12.8857239742286 | 0.0431597564770136 |
| White fish | Villonodular synovitis (pigmented) (finn-b-M13_VILLONODULAR) | rs138602679 | 9.95297422316631 | 4.62990783506739 | 0.0315779036583125 |
| White fish | Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) | rs138602679 | -1.40588206522119 | 0.697351044279695 | 0.0437966230223281 |
| White fish | Injury of muscle and tendon at shoulder and upper arm level (finn-b-ST19_INJURY_MUSCLE_TENDON_SHOUL_UPPER_ARM_LEVEL) | All - Inverse variance weighted | -1.2310428913536 | 0.556531257177641 | 0.0269671925344761 |
| White fish | Alkaline phosphatase, bone (prot-c-2795_23_3) | rs10089529 | 8.45334889638848 | 4.16624677833884 | 0.0424574546284934 |
| White fish | Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC (ukb-b-13151) | rs11098631 | 0.0308016990594492 | 0.0101777587406971 | 0.0024750638411601 |
| White fish | Operative procedures - main OPCS: W20.5 Primary open reduction of fracture of ankle and extramedullary fixation NEC (ukb-b-13151) | All - Inverse variance weighted | 0.0223828830941513 | 0.0082375077439082 | 0.006583857223022 |
| White fish | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | rs10089529 | 0.102825636991739 | 0.0513428572464267 | 0.045206786232609 |
| White fish | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | All - Inverse variance weighted | 0.0612368541401149 | 0.0255524091934485 | 0.0165515999678489 |
| White fish | Fractured heel (ukb-b-18389) | All - Inverse variance weighted | -0.0117293618872706 | 0.0054912911856932 | 0.0326799494508234 |
| White fish | Diagnoses - secondary ICD10: M47.82 Other spondylosis (Cervical region) (ukb-b-2625) | All - Inverse variance weighted | 0.0132668663934957 | 0.0062846701420437 | 0.0347733003727687 |
| White fish | Operation code: ankle surgery (ukb-b-4274) | rs61758614 | 0.0257449303647398 | 0.009627042620032 | 0.0074900965374155 |
| White fish | Operation code: ankle surgery (ukb-b-4274) | All - Inverse variance weighted | 0.0187194162415146 | 0.0071802068864121 | 0.0091316444705373 |
| White fish | Impingement syndrome of shoulder (ukb-d-M13_IMPINGEMENT) | rs111269255 | 0.0486766159710853 | 0.0213479804810149 | 0.0225987428620318 |
| White fish | Impingement syndrome of shoulder (ukb-d-M13_IMPINGEMENT) | All - Inverse variance weighted | 0.0226976737996289 | 0.0084565504949358 | 0.0072739586306343 |
| White fish | Impingement syndrome of shoulder (ukb-d-M13_IMPINGEMENT) | All - MR Egger | 0.040970780802634 | 0.0144670461998758 | 0.0472487659723629 |
| White fish | Shoulder lesions (ukb-d-M13_SHOULDER) | All - Inverse variance weighted | 0.0243577378045359 | 0.0122363553659952 | 0.0465244413515971 |
| White fish | Diagnoses - main ICD10: M75 Shoulder lesions (ukb-d-M75) | All - Inverse variance weighted | 0.0243090006332461 | 0.0122371817021595 | 0.0469792906300139 |
| White fish | Ankle spacing width (ukb-e-3143_AFR) | All - Inverse variance weighted | 1.65797808601614 | 0.658866851920566 | 0.0118557710990349 |
| White fish | Heel bone mineral density (BMD) (ukb-e-3148_AFR) | All - Inverse variance weighted | -1.60605079856962 | 0.809140113914655 | 0.0471571681101041 |
| White fish | Heel bone mineral density (BMD) T-score, automated (ukb-e-78_p1_AFR) | All - Inverse variance weighted | -1.68025161913131 | 0.81049426971254 | 0.0381611431364106 |