ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Sausage | Total body bone mineral density (ebi-a-GCST005348) | rs34269822 | 0.656043756244131 | 0.284910431283165 | 0.0212995808258321 |
| Sausage | Total body bone mineral density (ebi-a-GCST005348) | All - Inverse variance weighted | 0.149141312077687 | 0.0759354389785099 | 0.0495238155892763 |
| Sausage | Total body bone mineral density (age 45-60) (ebi-a-GCST005350) | rs117524659 | 1.64731239553092 | 0.764273774962611 | 0.0311308838678233 |
| Sausage | Total body bone mineral density (age 45-60) (ebi-a-GCST005350) | rs4245952 | -1.85470445612605 | 0.749480199216672 | 0.0133365168434353 |
| Sausage | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | rs117524659 | 6.16949283012228 | 2.44096947303598 | 0.0114885532394344 |
| Sausage | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | rs145497791 | 8.82269928747665 | 3.57108707850055 | 0.0134889604747392 |
| Sausage | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | rs2831441 | 4.91567125856795 | 1.99550782558217 | 0.0137638347061346 |
| Sausage | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | rs75139174 | 4.32525786323698 | 1.88768092873212 | 0.0219456230894494 |
| Sausage | Bone morphogenetic protein 6 levels (ebi-a-GCST90010107) | All - Inverse variance weighted | 1.97667404386305 | 0.791175830448214 | 0.0124755179908417 |
| Sausage | Osteoprotegerin levels (ebi-a-GCST90010243) | rs4245952 | 3.75309980865805 | 1.47856555706756 | 0.011138021143473 |
| Sausage | Osteoprotegerin levels (ebi-a-GCST90010243) | All - Inverse variance weighted | 1.28865308885318 | 0.596870497083214 | 0.0308489080180455 |
| Sausage | Osteopontin levels (ebi-a-GCST90010244) | All - Inverse variance weighted | 1.52854034247215 | 0.578354865487046 | 0.0082196677308407 |
| Sausage | Neck circumference (ebi-a-GCST90017134) | rs116938798 | -7.92685097729591 | 3.39692266451095 | 0.0196198822457891 |
| Sausage | Neck circumference (BMI adjusted) (ebi-a-GCST90017137) | rs116938798 | -7.92685097729591 | 3.39692266451095 | 0.0196198822457891 |
| Sausage | Achilles tendinitis (finn-b-M13_ACHILLESTEND) | All - Inverse variance weighted | -1.01004250626918 | 0.484383169818121 | 0.0370498910363705 |
| Sausage | Ankylosing spondylitis (finn-b-M13_ANKYLOSPON) | All - MR Egger | 3.53915496569929 | 1.27065892817555 | 0.0192748729214656 |
| Sausage | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | rs116938798 | 2.29742550121364 | 1.10578000423045 | 0.0377414677323008 |
| Sausage | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | All - MR Egger | 2.00138858044763 | 0.760588172574111 | 0.0251030760516198 |
| Sausage | Cervicalgia (finn-b-M13_CERVICALGIA) | rs117524659 | 4.06989531098795 | 1.6154218351368 | 0.0117554708589857 |
| Sausage | Cervicalgia (finn-b-M13_CERVICALGIA) | rs4245952 | -2.58691552632851 | 0.949802095781497 | 0.006456755446978 |
| Sausage | Cervicalgia (finn-b-M13_CERVICALGIA) | rs75139174 | -2.27885309223651 | 1.13014134725583 | 0.0437548300034802 |
| Sausage | Cervicalgia (finn-b-M13_CERVICALGIA) | All - MR Egger | 2.33996991465016 | 0.905573598042245 | 0.0272304773553194 |
| Sausage | Loose body in joint (finn-b-M13_LOOSEJOINT) | rs75139174 | 7.01430451207606 | 3.34267159047498 | 0.0358687045065121 |
| Sausage | Loose body in joint (finn-b-M13_LOOSEJOINT) | All - Inverse variance weighted | 2.16374052071139 | 1.01293776933072 | 0.0326709297670279 |
| Sausage | Osteomalacia (finn-b-M13_OSTEOMALACIA) | All - Inverse variance weighted | 4.55695643873163 | 1.75600099743612 | 0.009456994326888 |
| Sausage | Shoulder lesions (finn-b-M13_SHOULDER) | All - Inverse variance weighted | 0.344861606874735 | 0.160849637298482 | 0.0320328945025865 |
| Sausage | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | rs116938798 | 2.37910243334429 | 1.01572595085562 | 0.0191669440799126 |
| Sausage | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | All - MR Egger | 1.84215227358775 | 0.695599482191201 | 0.0243843350171711 |
| Sausage | Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) | rs4245952 | -2.41767806198927 | 1.00160948282412 | 0.0157874242343648 |
| Sausage | Spondyloarthritis (finn-b-SPONDYLOARTHRITIS) | All - MR Egger | 2.81451221064667 | 0.913081649040912 | 0.0115925132155661 |
| Sausage | Contusion of ankle (finn-b-ST19_CONTU_ANKLE) | All - Inverse variance weighted | -2.07976140847966 | 0.889672338915197 | 0.0194043110313484 |
| Sausage | Fracture of femur (finn-b-ST19_FRACT_FEMUR) | All - Inverse variance weighted | 0.674980244433995 | 0.315320172194152 | 0.0323048027647098 |
| Sausage | Injuries to the elbow and forearm (finn-b-ST19_INJURI_ELBOW_FOREA) | All - Inverse variance weighted | 0.459939136695087 | 0.179241607994132 | 0.010287027259686 |
| Sausage | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | rs75139174 | -15.7238210450359 | 6.87104715819857 | 0.0221132492490303 |
| Sausage | Injury of nerves at ankle and foot level (finn-b-ST19_INJURY_NERVES_ANKLE_FOOT_LEVEL) | All - Inverse variance weighted | -4.3959990408566 | 2.06816963491462 | 0.0335407033686393 |
| Sausage | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | rs75139174 | 6.14680164692899 | 2.87045290547137 | 0.032241407720248 |
| Sausage | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | All - Inverse variance weighted | 2.1810166637928 | 0.870033290240354 | 0.0121822806168773 |
| Sausage | Psoriatic arthritis (ieu-b-5116) | rs116719977 | -3.73388636139193 | 0.874468853616666 | 1.95568847650435e-05 |
| Sausage | Psoriatic arthritis (ieu-b-5116) | rs116938798 | -4.02455753092728 | 1.02397741528113 | 8.48333589631422e-05 |
| Sausage | Psoriatic arthritis (ieu-b-5116) | rs12498806 | -2.05812632994851 | 0.987510887661385 | 0.0371460174871433 |
| Sausage | Psoriatic arthritis (ieu-b-5116) | All - Inverse variance weighted | -1.3431703419362 | 0.493909508903513 | 0.0065387326610265 |
| Sausage | Psoriatic arthritis (ieu-b-5116) | All - MR Egger | -3.04055650143564 | 1.1189004871685 | 0.0216548938431032 |
| Sausage | Pain type(s) experienced in last month: Knee pain (ukb-a-476) | rs11829741 | -0.103680316422209 | 0.0497781228044306 | 0.0372649838424311 |
| Sausage | Pain type(s) experienced in last month: Knee pain (ukb-a-476) | rs144214838 | -0.122259821512287 | 0.0471878382870635 | 0.0095720285212742 |
| Sausage | Pain type(s) experienced in last month: Knee pain (ukb-a-476) | All - MR Egger | -0.0948244068079462 | 0.0275255098450614 | 0.0048498344976726 |
| Sausage | Heel bone mineral density (BMD) (left) (ukb-b-1096) | rs12498806 | 0.35096858840781 | 0.170994167521141 | 0.040119357960561 |
| Sausage | Heel bone mineral density (BMD) (left) (ukb-b-1096) | rs2831441 | -0.33956909062493 | 0.171513987809507 | 0.0477222723148387 |
| Sausage | Heel bone mineral density (BMD) (left) (ukb-b-1096) | rs76866342 | 0.420674316183294 | 0.168572417551664 | 0.0125775868359377 |
| Sausage | Heel bone mineral density (BMD) (left) (ukb-b-1096) | All - MR Egger | 0.225189517499221 | 0.0972916129046923 | 0.0376261136536396 |
| Sausage | Diagnoses - main ICD10: M75.4 Impingement syndrome of shoulder (ukb-b-1418) | All - Inverse variance weighted | -0.0112000872011235 | 0.0057054264314549 | 0.0496393494872483 |
| Sausage | Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) | rs12498806 | 0.361613689235824 | 0.171071345880329 | 0.0345308154571733 |
| Sausage | Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) | rs76866342 | 0.409766390243184 | 0.168621761352757 | 0.0150949913988123 |
| Sausage | Heel bone mineral density (BMD) T-score, automated (left) (ukb-b-15730) | All - MR Egger | 0.224751010600168 | 0.0945829623074391 | 0.0335432813355076 |
| Sausage | Ankle spacing width (left) (ukb-b-2122) | rs117524659 | 0.39936438814111 | 0.154011612562681 | 0.0095120720828159 |
| Sausage | Ankle spacing width (left) (ukb-b-2122) | All - MR Egger | 0.183653950640045 | 0.0813769041098128 | 0.0418757171578996 |
| Sausage | Operation code: shoulder surgery (ukb-b-5935) | rs75139174 | -0.0270302750541194 | 0.0124215002759031 | 0.0295486969174304 |
| Sausage | Operation code: shoulder surgery (ukb-b-5935) | All - Inverse variance weighted | -0.0127526408051394 | 0.0054159772101572 | 0.0185409876247879 |
| Sausage | Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) | rs144214838 | -0.0307335555195663 | 0.0124045551019017 | 0.0132268447297062 |
| Sausage | Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) | rs17059045 | -0.025605460587849 | 0.0116509566421011 | 0.0279695540732119 |
| Sausage | Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) | All - Inverse variance weighted | -0.0106686390077526 | 0.0033958595365323 | 0.0016799249634671 |
| Sausage | Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) | rs17059045 | -2.29072279379736 | 0.978863881094682 | 0.0192741781086306 |
| Sausage | Heel bone mineral density (BMD) (left) (ukb-e-4105_EAS) | rs76866342 | 2.81554256086963 | 1.20560899088244 | 0.0195241222283768 |
| Sausage | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) | rs76866342 | -1.24758804554359 | 0.524296298478443 | 0.0173338999413606 |
| Sausage | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_AFR) | All - Inverse variance weighted | -0.464751882925882 | 0.234937185999998 | 0.0479065607724235 |
| Sausage | M75 Shoulder lesions (ukb-e-M75_CSA) | All - MR Egger | 4.72806298213581 | 1.98270939541181 | 0.048549268805347 |