ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Cucumber | Rheumatoid Arthritis (bbj-a-74) | rs2232354 | -2.75454033201855 | 0.890006212705706 | 0.0019683444238257 |
| Cucumber | Rheumatoid arthritis (ebi-a-GCST002318) | rs2232354 | -2.62128140667216 | 1.01842139482467 | 0.0100568871146005 |
| Cucumber | Rheumatoid arthritis (ebi-a-GCST002318) | rs4343301 | 1.28898172414846 | 0.657642846863975 | 0.0499954802862695 |
| Cucumber | Total body bone mineral density (age 0-15) (ebi-a-GCST005345) | rs35040843 | 1.25366611075968 | 0.55974083232695 | 0.0251087147774743 |
| Cucumber | Total body bone mineral density (age 0-15) (ebi-a-GCST005345) | rs4254639 | -1.10714425724679 | 0.475842220452834 | 0.0199809957713187 |
| Cucumber | Total body bone mineral density (age 0-15) (ebi-a-GCST005345) | All - MR Egger | -0.697449572833686 | 0.304448698587359 | 0.0368694963571155 |
| Cucumber | Neck injury (ebi-a-GCST90038700) | rs148590142 | 0.0199649581312807 | 0.0077040134665405 | 0.0095558280858994 |
| Cucumber | Neck injury (ebi-a-GCST90038700) | rs77781525 | -0.0243731732239182 | 0.0077948782941376 | 0.0017670870737566 |
| Cucumber | Neck injury (ebi-a-GCST90038700) | rs78250650 | 0.0164141000045095 | 0.0081643121564061 | 0.0443815285846855 |
| Cucumber | Fractures (ebi-a-GCST90038703) | All - MR Egger | -0.0129835998317528 | 0.0060010027662545 | 0.0497079876940657 |
| Cucumber | Malignant neoplasm of bone and articular cartilage (finn-b-C3_BONE_CARTILAGE) | All - MR Egger | 4.92634266517383 | 2.20587735952672 | 0.0411884929568624 |
| Cucumber | Malignant neoplasm of bone and articular cartilage (all cancers excluded) (finn-b-C3_BONE_CARTILAGE_EXALLC) | All - MR Egger | 4.99964343154619 | 2.21062429979145 | 0.0390051367583463 |
| Cucumber | Adhesive capsulitis of shoulder (finn-b-M13_ADHCAPSULITIS) | All - Inverse variance weighted | 0.586439477294347 | 0.253861371218823 | 0.0208838561195155 |
| Cucumber | Bicipital tendinitis (finn-b-M13_BICIPITALTEND) | rs140812249 | 3.4192471080887 | 1.51235929780846 | 0.0237673352613926 |
| Cucumber | Bicipital tendinitis (finn-b-M13_BICIPITALTEND) | rs183032803 | 4.9980482473261 | 1.98610352096182 | 0.0118523727080778 |
| Cucumber | Bicipital tendinitis (finn-b-M13_BICIPITALTEND) | rs7328844 | 4.32163150930178 | 2.01136452089982 | 0.031665581311785 |
| Cucumber | Bicipital tendinitis (finn-b-M13_BICIPITALTEND) | All - Inverse variance weighted | 1.32788917909425 | 0.530509661376725 | 0.0123130134190301 |
| Cucumber | Chondromalacia (finn-b-M13_CHONDROMALACIA) | rs117632321 | 5.7080346792496 | 2.5568599278332 | 0.0255859404560149 |
| Cucumber | Chondromalacia (finn-b-M13_CHONDROMALACIA) | All - MR Egger | 3.3230558017133 | 1.16756028271523 | 0.0122615223056383 |
| Cucumber | Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) | rs183032803 | -8.13490514482005 | 3.67241783121243 | 0.0267507273777046 |
| Cucumber | Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) | All - Inverse variance weighted | -1.94909807612387 | 0.94228476582383 | 0.0385948212760621 |
| Cucumber | Impingement syndrome of shoulder (finn-b-M13_IMPINGEMENT) | rs140812249 | 1.21819330166723 | 0.5762192747943 | 0.0345055219817355 |
| Cucumber | Impingement syndrome of shoulder (finn-b-M13_IMPINGEMENT) | rs4254639 | 1.62624486137716 | 0.712411506189328 | 0.0224461332327299 |
| Cucumber | Impingement syndrome of shoulder (finn-b-M13_IMPINGEMENT) | rs77781525 | 1.86301456668277 | 0.754077324609694 | 0.0134891037280277 |
| Cucumber | Impingement syndrome of shoulder (finn-b-M13_IMPINGEMENT) | All - Inverse variance weighted | 0.476571436481018 | 0.232713195864731 | 0.0405706063474881 |
| Cucumber | Loose body in joint (finn-b-M13_LOOSEJOINT) | All - MR Egger | -2.94362942121806 | 1.27466957577957 | 0.0355767488042812 |
| Cucumber | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | rs117632321 | -4.40103188727611 | 1.43680506800333 | 0.0021908013757422 |
| Cucumber | Pathological/recurrent dislocation and subluxation of joint, not elsewhere classified (finn-b-M13_PATHODISLOCATIO) | All - MR Egger | -1.77473108656586 | 0.707112871891229 | 0.0240348468383597 |
| Cucumber | Pyogenic arthritis (finn-b-M13_PYOGARTH) | rs117632321 | 3.3446536156873 | 1.6131402354401 | 0.0381368760397568 |
| Cucumber | Pyogenic arthritis (finn-b-M13_PYOGARTH) | All - Inverse variance weighted | 0.821385370198752 | 0.409394497604633 | 0.0448197731368995 |
| Cucumber | Shoulder lesions (finn-b-M13_SHOULDER) | rs4254639 | 1.00440559601266 | 0.410954644936539 | 0.0145222483050517 |
| Cucumber | Shoulder lesions (finn-b-M13_SHOULDER) | rs76515994 | 0.96548326274599 | 0.385624816425533 | 0.0122907231005575 |
| Cucumber | Shoulder lesions (finn-b-M13_SHOULDER) | All - Inverse variance weighted | 0.303620205293102 | 0.115424955583496 | 0.0085270540897935 |
| Cucumber | Injuries to the neck (finn-b-ST19_INJURI_NECK) | rs140812249 | -1.52706759761553 | 0.689559702719305 | 0.0267906525240073 |
| Cucumber | Injuries to the neck (finn-b-ST19_INJURI_NECK) | All - Inverse variance weighted | -0.500329915600613 | 0.235726084670718 | 0.0337953097596429 |
| Cucumber | Injury of muscle and tendon at lower leg level (finn-b-ST19_INJURY_MUSCLE_TENDON_LOWER_LEG_LEVEL) | All - Inverse variance weighted | -0.762386277988372 | 0.290182417202628 | 0.0086074124576276 |
| Cucumber | Injury of nerves at shoulder and upper arm level (finn-b-ST19_INJURY_NERVES_SHOUL_UPPER_ARM_LEVEL) | rs140812249 | 8.35431429041105 | 3.36820065581713 | 0.0131253716637058 |
| Cucumber | Injury of nerves at shoulder and upper arm level (finn-b-ST19_INJURY_NERVES_SHOUL_UPPER_ARM_LEVEL) | rs183032803 | 10.7705519556562 | 4.61082051682411 | 0.0194949128850458 |
| Cucumber | Injury of nerves at shoulder and upper arm level (finn-b-ST19_INJURY_NERVES_SHOUL_UPPER_ARM_LEVEL) | All - MR Egger | 6.36049839928334 | 2.11399215964218 | 0.0088140548207692 |
| Cucumber | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | rs4254639 | -8.653028559996 | 2.92805184517284 | 0.0031244921174837 |
| Cucumber | Other and unspecified injuries of shoulder and upper arm (finn-b-ST19_OTHER_UNSPE_INJURI_SHOUL_UPPER_ARM) | rs7328844 | -6.73153265353779 | 3.15093017825173 | 0.0326497856176951 |
| Cucumber | Osteomyelitis (ieu-b-4975) | rs183032803 | -1.86663283628699 | 0.89554219689281 | 0.0371273823906243 |
| Cucumber | Osteomyelitis (ieu-b-4975) | rs2232354 | 2.10117680204586 | 0.956698886047419 | 0.0280720449770326 |
| Cucumber | Osteomyelitis (ieu-b-4975) | rs7328844 | -1.8901907060014 | 0.904743519887912 | 0.0366896693152229 |
| Cucumber | Osteomyelitis (ieu-b-4975) | All - MR Egger | -1.05506805911137 | 0.430495241656887 | 0.0269976341428256 |
| Cucumber | Bone sialoprotein 2 (prot-a-1396) | rs2232354 | 2.5717711990522 | 1.13056795688671 | 0.0229203079710577 |
| Cucumber | Bone sialoprotein 2 (prot-a-1396) | All - MR Egger | -1.15642404986071 | 0.477004287268517 | 0.0284371772650551 |
| Cucumber | Alkaline phosphatase, bone (prot-c-2795_23_3) | rs4254639 | 3.45120792277297 | 1.59115149761876 | 0.030082668426997 |
| Cucumber | Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) | rs76515994 | -0.0580601271519665 | 0.0294825805595824 | 0.0489183348979959 |
| Cucumber | Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) | rs77781525 | -0.0677945614549257 | 0.0289155385870555 | 0.0190489334304332 |
| Cucumber | Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) | All - Inverse variance weighted | -0.0184012985896713 | 0.0073657090579363 | 0.0124812159267332 |
| Cucumber | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | rs28567375 | 0.368488060846251 | 0.187084538889834 | 0.0488803368560542 |
| Cucumber | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | rs35040843 | -0.360711177564361 | 0.177211647209922 | 0.0418023641632203 |
| Cucumber | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | rs4254639 | 0.533574588943968 | 0.175381653849117 | 0.0023472893118037 |
| Cucumber | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | rs79041188 | 0.512728086367959 | 0.180220394920848 | 0.004441060082675 |
| Cucumber | Heel bone mineral density (BMD) T-score automated (right) (ukb-a-362) | All - MR Egger | 0.301103362305176 | 0.119451715612207 | 0.0244669563746702 |
| Cucumber | Non-cancer illness code, self-reported: cervical spondylosis (ukb-b-2349) | rs4343301 | 0.0178423506120295 | 0.0077995281681849 | 0.0221597051186049 |
| Cucumber | Non-cancer illness code, self-reported: cervical spondylosis (ukb-b-2349) | All - Inverse variance weighted | 0.0087274358827556 | 0.00383162049316 | 0.0227420633605492 |
| Cucumber | Operative procedures - main OPCS: W91.9 Unspecified other manipulation of joint (ukb-b-4663) | rs4343301 | -0.0088129636009227 | 0.0044041270021236 | 0.0453849157651968 |
| Cucumber | Non-cancer illness code, self-reported: other joint disorder (ukb-b-5316) | rs7328844 | 0.0153744531797307 | 0.006985350665525 | 0.0277391011856142 |
| Cucumber | Non-cancer illness code, self-reported: other joint disorder (ukb-b-5316) | All - Inverse variance weighted | 0.0122356982397759 | 0.0035862092233679 | 0.0006451764870787 |
| Cucumber | Adhesive capsulitis of shoulder (ukb-d-M13_ADHCAPSULITIS) | All - Inverse variance weighted | -0.0038195643383724 | 0.0016416231399414 | 0.0199812450446156 |
| Cucumber | Ankle spacing width (ukb-e-3143_EAS) | All - MR Egger | 2.70002337713106 | 1.0352957068983 | 0.0477866608804642 |
| Cucumber | Osteoarthrosis (ukb-e-740_CSA) | All - Inverse variance weighted | 2.52096776211713 | 0.853838462064754 | 0.0031520046825147 |
| Cucumber | M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_CSA) | rs9289020 | 6.63523452224528 | 2.36632915757493 | 0.0050469758540203 |
| Cucumber | M17 Gonarthrosis [arthrosis of knee] (ukb-e-M17_CSA) | All - Inverse variance weighted | 2.13453695140195 | 0.923309828240498 | 0.0207869584796275 |