ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Peach/nectarine | Osteoprotegerin levels (ebi-a-GCST90000490) | All - MR Egger | 6.64963431194124 | 2.90758652001954 | 0.0411546145539675 |
| Peach/nectarine | Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016610) | rs7006940 | -0.599838043728193 | 0.296586588287829 | 0.0431276226781775 |
| Peach/nectarine | Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016610) | rs7032259 | -0.677446273891528 | 0.274057810801573 | 0.0134393303230719 |
| Peach/nectarine | Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016610) | All - Inverse variance weighted | -0.190551019874846 | 0.0884321511879685 | 0.0311797719099941 |
| Peach/nectarine | Achilles tendon injury (ebi-a-GCST90018787) | rs73013804 | -4.69740694710678 | 1.13538221726034 | 3.51429873684738e-05 |
| Peach/nectarine | Achilles tendon injury (ebi-a-GCST90018787) | All - Inverse variance weighted | -0.915588719086133 | 0.285613224921477 | 0.0013473699476037 |
| Peach/nectarine | Achilles tendon injury (ebi-a-GCST90018787) | All - MR Egger | -1.68221380484082 | 0.689651352902725 | 0.0276196244860868 |
| Peach/nectarine | Pain in joint (finn-b-JOINTPAIN) | rs62140616 | -1.37056619270058 | 0.646784045993532 | 0.0340864428132274 |
| Peach/nectarine | Pain in joint (finn-b-JOINTPAIN) | All - Inverse variance weighted | -0.465424407566295 | 0.216095555909086 | 0.0312566587344368 |
| Peach/nectarine | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | rs78476393 | 15.7333714989764 | 6.30977641985526 | 0.0126493746775286 |
| Peach/nectarine | Other acquired deformities of ankle and foot (finn-b-M13_ANKLEFOOT) | All - MR Egger | 12.4951463006581 | 5.53778980366543 | 0.0394048415628159 |
| Peach/nectarine | Cervical disc disorders (finn-b-M13_CERVICDISC) | All - Inverse variance weighted | 0.59323700863286 | 0.282003820497191 | 0.0354090906293502 |
| Peach/nectarine | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | rs6727287 | 8.15681890562138 | 3.58120096971903 | 0.0227458319796312 |
| Peach/nectarine | Radial styloid tenosynovitis [de Quervain] (finn-b-M13_DEQUERVAIN) | All - MR Egger | -6.44529597936278 | 2.00246862965047 | 0.0057400882541844 |
| Peach/nectarine | Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) | rs75548124 | -7.25020897661168 | 3.64311154328043 | 0.04657832782245 |
| Peach/nectarine | Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) | rs78476393 | -7.9786936149294 | 4.00988158279559 | 0.0466176095497497 |
| Peach/nectarine | Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) | All - MR Egger | -8.39625297290399 | 3.61997760769531 | 0.0348882515590653 |
| Peach/nectarine | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | rs78476393 | 3.47099929683951 | 1.58677809375058 | 0.028709618000749 |
| Peach/nectarine | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | All - MR Egger | 3.84625685874901 | 1.4008651338897 | 0.0150176460364769 |
| Peach/nectarine | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | rs111855924 | -14.2148912078832 | 6.12269879644486 | 0.0202506666833576 |
| Peach/nectarine | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | rs2943329 | -19.4015490783745 | 9.76191629808569 | 0.0468699596188891 |
| Peach/nectarine | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | rs7006940 | -14.8459915822728 | 5.92173446502778 | 0.0121748887187102 |
| Peach/nectarine | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | rs75548124 | -7.5705450072123 | 3.24885181331044 | 0.0197944364495519 |
| Peach/nectarine | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | rs78907083 | 17.5758083197276 | 6.33538465832182 | 0.0055332700607708 |
| Peach/nectarine | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | All - Inverse variance weighted | -4.39234127074157 | 1.7725525657136 | 0.0132130334730769 |
| Peach/nectarine | Dislocation, sprain and strain of joints and ligaments of elbow (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ELBOW) | rs6727287 | -9.12523804262344 | 3.41221508004082 | 0.0074888618778172 |
| Peach/nectarine | Dislocation, sprain and strain of joints and ligaments of elbow (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_ELBOW) | All - MR Egger | 4.33928446798289 | 1.90426215894077 | 0.0377431019653004 |
| Peach/nectarine | Injuries to the abdomen, lower back, lumbar spine and pelvis (finn-b-ST19_INJURI_ABDOMEN_LOWER_BACK_LUMBAR_SPINE_PELVIS) | rs78476393 | -1.74483363720652 | 0.825124608750303 | 0.0344614548091272 |
| Peach/nectarine | Injuries to the abdomen, lower back, lumbar spine and pelvis (finn-b-ST19_INJURI_ABDOMEN_LOWER_BACK_LUMBAR_SPINE_PELVIS) | All - MR Egger | -1.62666373728145 | 0.730289052349327 | 0.0416532531160416 |
| Peach/nectarine | Injury of nerves at shoulder and upper arm level (finn-b-ST19_INJURY_NERVES_SHOUL_UPPER_ARM_LEVEL) | rs75548124 | 11.4998739506152 | 4.89791895308878 | 0.0188790714578471 |
| Peach/nectarine | Injury of nerves at shoulder and upper arm level (finn-b-ST19_INJURY_NERVES_SHOUL_UPPER_ARM_LEVEL) | rs78476393 | 10.7913355693422 | 5.43984866492847 | 0.0472829829801861 |
| Peach/nectarine | Injury of nerves at shoulder and upper arm level (finn-b-ST19_INJURY_NERVES_SHOUL_UPPER_ARM_LEVEL) | rs78907083 | 26.5939632436053 | 9.60424777773126 | 0.0056232208567948 |
| Peach/nectarine | Injury of nerves at shoulder and upper arm level (finn-b-ST19_INJURY_NERVES_SHOUL_UPPER_ARM_LEVEL) | All - Inverse variance weighted | 4.84219199305723 | 2.07685912930127 | 0.0197271385667017 |
| Peach/nectarine | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | rs75548124 | -3.77389962678009 | 1.78743714116204 | 0.0347425171389886 |
| Peach/nectarine | Osteoclast-associated immunoglobulin-like receptor (prot-a-2153) | All - Inverse variance weighted | -0.83256951416179 | 0.407853356935013 | 0.0412165220062962 |
| Peach/nectarine | Fractured bone site(s): Other bones (ukb-a-441) | rs184625579 | 0.0802885574136904 | 0.0374919863751648 | 0.0322348802947993 |
| Peach/nectarine | Fractured bone site(s): Other bones (ukb-a-441) | All - Inverse variance weighted | 0.0188928335093858 | 0.0092211974585127 | 0.0404769641195397 |
| Peach/nectarine | Diagnoses - main ICD10: S66 Injury of muscle and tendon at wrist and hand level (ukb-a-591) | rs73013804 | -0.0189899521833463 | 0.0068433004023339 | 0.0055206828209583 |
| Peach/nectarine | Diagnoses - main ICD10: S66 Injury of muscle and tendon at wrist and hand level (ukb-a-591) | All - Inverse variance weighted | -0.0043490512899853 | 0.0018330987083308 | 0.0176675211978017 |
| Peach/nectarine | Diagnoses - main ICD10: S66 Injury of muscle and tendon at wrist and hand level (ukb-a-591) | All - MR Egger | -0.0098136921034282 | 0.004535689805541 | 0.0482719306409401 |
| Peach/nectarine | Diagnoses - main ICD10: M51.3 Other specified intervertebral disk degeneration (ukb-b-19807) | rs6727287 | -0.0169798971785856 | 0.006729473088997 | 0.0116287783360156 |
| Peach/nectarine | Diagnoses - main ICD10: M54.56 Low back pain (Lumbar region) (ukb-b-19813) | rs6727287 | -0.01541144814408 | 0.0078508244561579 | 0.049642033937753 |
| Peach/nectarine | Non-cancer illness code, self-reported: joint pain (ukb-b-4122) | rs6727287 | -0.0212161134545265 | 0.0082059548027739 | 0.0097251027909688 |
| Peach/nectarine | Diagnoses - main ICD10: M51 Other intervertebral disk disorders (ukb-d-M51) | All - Inverse variance weighted | 0.010911600869605 | 0.0046546651261813 | 0.0190664619470331 |
| Peach/nectarine | Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) | rs149599449 | 0.0442454744750507 | 0.0178471992045078 | 0.013170438035832 |
| Peach/nectarine | Diagnoses - main ICD10: S82 Fracture of lower leg, including ankle (ukb-d-S82) | rs28542413 | -0.0405014151181406 | 0.0165558730843154 | 0.014431192072955 |