ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Watercress | Rheumatoid arthritis (ebi-a-GCST000679) | rs1447897 | 5.44461522367161 | 2.215012835266 | 0.0139693210114947 |
| Watercress | Rheumatoid arthritis (ebi-a-GCST000679) | All - Inverse variance weighted | 4.09392684529677 | 1.72665954044555 | 0.0177395564488399 |
| Watercress | Knee osteoarthritis (ebi-a-GCST007090) | All - MR Egger | -1.10802446534015 | 0.44149312813757 | 0.0309274004287338 |
| Watercress | Osteoarthritis of the hip or knee (ebi-a-GCST007092) | rs55718637 | -1.5181586852674 | 0.631668861955231 | 0.0162430051045951 |
| Watercress | Osteoarthritis of the hip or knee (ebi-a-GCST007092) | All - Inverse variance weighted | -0.421095660607118 | 0.191659708463063 | 0.0280132622281457 |
| Watercress | Osteoarthritis (Firth correction) (ebi-a-GCST90013881) | rs1447897 | -1.52721961582721 | 0.676342069897881 | 0.0239420442055761 |
| Watercress | Osteoarthritis (Firth correction) (ebi-a-GCST90013881) | All - Inverse variance weighted | -0.48912821650791 | 0.202105717034344 | 0.0155136700276925 |
| Watercress | Osteoarthritis (SPA correction) (ebi-a-GCST90013931) | rs1447897 | -1.52611715097331 | 0.675293521208366 | 0.0238254978852427 |
| Watercress | Osteoarthritis (SPA correction) (ebi-a-GCST90013931) | All - Inverse variance weighted | -0.489317500639598 | 0.202077679122273 | 0.0154594632226461 |
| Watercress | Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016610) | rs116023894 | 0.535359132289918 | 0.251618792176262 | 0.0333653189448041 |
| Watercress | Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016610) | All - MR Egger | 0.582827958763125 | 0.222782450229882 | 0.0473182111195562 |
| Watercress | Osteoarthritis (ebi-a-GCST90038686) | All - Inverse variance weighted | -0.0267604762494224 | 0.0128859828221144 | 0.0378281405648428 |
| Watercress | Benign neoplasm: Short bones of lower limb (finn-b-CD2_BENIGN_BONE_SHORT_LOWER) | All - Inverse variance weighted | -5.94318366532007 | 2.75421076116384 | 0.0309392143359344 |
| Watercress | Benign neoplasm: Short bones of lower limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_LOWER_EXALLC) | All - Inverse variance weighted | -5.90427787488021 | 2.75191794132571 | 0.0319117905543135 |
| Watercress | Melanocytic naevi of upper limb, including shoulder (finn-b-CD2_BENIGN_MELANOCYTIC_UPPERLIMB) | rs61917839 | -15.6431425905215 | 7.73608964176064 | 0.043166079096483 |
| Watercress | Melanocytic naevi of upper limb, including shoulder (finn-b-CD2_BENIGN_MELANOCYTIC_UPPERLIMB) | All - Inverse variance weighted | -4.51584650561107 | 2.11400297496552 | 0.032666455107748 |
| Watercress | Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) | rs187693683 | 13.5104528421024 | 6.12723229605633 | 0.0274551753317577 |
| Watercress | Benign neoplasm: Skin of upper limb, including shoulder (finn-b-CD2_BENIGN_SKIN_UPPERLIMB) | All - MR Egger | 7.95759497924493 | 3.39484255968083 | 0.0410568625190756 |
| Watercress | Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) | rs116023894 | 19.8966221515548 | 9.32060249316748 | 0.0327861192452538 |
| Watercress | Other bursitis of elbow (finn-b-M13_BURSELBOWOTH) | All - MR Egger | 16.8065877082491 | 6.06604224159214 | 0.0197668752438836 |
| Watercress | Osteopathies and chondropathies (finn-b-M13_OSTEOCHONDRO) | rs114107092 | -3.0172806597863 | 1.45951518465359 | 0.0387042865145395 |
| Watercress | Osteopathies and chondropathies (finn-b-M13_OSTEOCHONDRO) | rs191852210 | 2.12558804524842 | 0.632998365606991 | 0.0007851779680607 |
| Watercress | Osteopathies and chondropathies (finn-b-M13_OSTEOCHONDRO) | All - Inverse variance weighted | 0.891401037568521 | 0.441524727368434 | 0.0434960213184441 |
| Watercress | Osteoporosis (finn-b-M13_OSTEOPOROSIS) | rs191852210 | 4.11668221143023 | 1.06425591261406 | 0.0001096723536822 |
| Watercress | Osteoporosis (finn-b-M13_OSTEOPOROSIS) | All - Inverse variance weighted | 1.76449311081511 | 0.724694454254804 | 0.0148996219925135 |
| Watercress | Osteoporosis (finn-b-M13_OSTEOPOROSIS) | All - MR Egger | 2.8901260348008 | 1.26278490057171 | 0.0451139248501255 |
| Watercress | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | All - Inverse variance weighted | 3.32161380935116 | 1.38796244148611 | 0.0167040333060102 |
| Watercress | Disorders of synovium and tendon in diseases classified elsewhere (finn-b-M13_SYNOTENDINOTH) | All - Inverse variance weighted | 4.25279927628298 | 1.98624748079448 | 0.032264156427974 |
| Watercress | Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) | rs191852210 | 1.50720857953997 | 0.475114246702707 | 0.0015123268262511 |
| Watercress | Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) | All - Inverse variance weighted | 0.698114873177021 | 0.255618444093365 | 0.0063126806580419 |
| Watercress | Articial joint operation, menisceal resection (finn-b-OPER_ARTIF_JOINT_MENISC_RESECT) | All - MR Egger | 1.26440354764334 | 0.445286228628923 | 0.0175625475928018 |
| Watercress | Osteoporosis with pathological fracture (FG) (finn-b-OSTEOPOROSIS_FRACTURE_FG) | rs191852210 | 10.1996064592147 | 2.23815357446721 | 5.18518545309844e-06 |
| Watercress | Osteoporosis with pathological fracture (FG) (finn-b-OSTEOPOROSIS_FRACTURE_FG) | All - Inverse variance weighted | 3.26450808512355 | 1.59290506804158 | 0.0404224996524631 |
| Watercress | Osteoporosis with pathological fracture (FG) (finn-b-OSTEOPOROSIS_FRACTURE_FG) | All - MR Egger | 7.67370139730812 | 2.4197495722031 | 0.0099659723945616 |
| Watercress | Postmenopausal osteoporosis with pathological fracture (finn-b-OSTPOPATFRCTURE_POSTEMENO) | rs191852210 | 8.83127742871094 | 2.42673738315844 | 0.000273532401495 |
| Watercress | Postmenopausal osteoporosis with pathological fracture (finn-b-OSTPOPATFRCTURE_POSTEMENO) | rs7704452 | -11.1548334225088 | 5.2082980582327 | 0.0322142068876543 |
| Watercress | Postmenopausal osteoporosis with pathological fracture (finn-b-OSTPOPATFRCTURE_POSTEMENO) | All - Inverse variance weighted | 3.30614966538691 | 1.62075077782399 | 0.0413615066463395 |
| Watercress | Postmenopausal osteoporosis with pathological fracture (finn-b-OSTPOPATFRCTURE_POSTEMENO) | All - MR Egger | 8.50975783704026 | 2.25608977077915 | 0.0036501084993272 |
| Watercress | Seropositive rheumatoid arthritis, strict definition (finn-b-RHEUMA_SEROPOS_STRICT) | rs191852210 | -3.79360452367238 | 1.63731678863702 | 0.0205056773393939 |
| Watercress | Seropositive rheumatoid arthritis, strict definition (finn-b-RHEUMA_SEROPOS_STRICT) | rs7704452 | 7.25368949332539 | 3.57604860175145 | 0.042518513040939 |
| Watercress | Seropositive rheumatoid arthritis, strict definition (finn-b-RHEUMA_SEROPOS_STRICT) | All - MR Egger | -3.96471181193103 | 1.7558600058644 | 0.0475305869073153 |
| Watercress | Burn and corrosion of head and neck (finn-b-ST19_BURN_CORROSION_HEAD_NECK) | All - Inverse variance weighted | -4.23356164639491 | 1.79018993683267 | 0.0180365322094519 |
| Watercress | Contusion of ankle (finn-b-ST19_CONTU_ANKLE) | rs187693683 | 11.0876995511386 | 4.72368258500226 | 0.0189121776345942 |
| Watercress | Contusion of ankle (finn-b-ST19_CONTU_ANKLE) | All - Inverse variance weighted | 3.89707466159131 | 1.45751579087447 | 0.007500192897075 |
| Watercress | Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) | rs116023894 | 2.13340614217532 | 0.808392289757777 | 0.0083133114754033 |
| Watercress | Dislocation, sprain and strain of joints and ligaments of knee (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_KNEE) | All - MR Egger | 1.251755411248 | 0.527075495715082 | 0.0389496027064675 |
| Watercress | Fracture of neck (finn-b-ST19_FRACT_NECK) | rs115479010 | 12.2099717225308 | 6.16577781462139 | 0.0476719795515417 |
| Watercress | Fracture of neck (finn-b-ST19_FRACT_NECK) | rs61917839 | -13.9050156360191 | 4.92231854738177 | 0.004729663443502 |
| Watercress | Fracture of neck (finn-b-ST19_FRACT_NECK) | rs76868681 | 14.1664988420099 | 6.23521045211962 | 0.0230855349426998 |
| Watercress | Fracture of neck (finn-b-ST19_FRACT_NECK) | All - MR Egger | 6.05424986809135 | 2.55185629473705 | 0.0391107511815123 |
| Watercress | Injury of muscle and tendon at lower leg level (finn-b-ST19_INJURY_MUSCLE_TENDON_LOWER_LEG_LEVEL) | rs114107092 | 6.75506344975281 | 2.97883489394664 | 0.0233483258654616 |
| Watercress | Injury of muscle and tendon at lower leg level (finn-b-ST19_INJURY_MUSCLE_TENDON_LOWER_LEG_LEVEL) | rs12141896 | 9.12375906589167 | 3.55241499922843 | 0.01021910625202 |
| Watercress | Injury of muscle and tendon at lower leg level (finn-b-ST19_INJURY_MUSCLE_TENDON_LOWER_LEG_LEVEL) | rs1447897 | 7.87819775161547 | 2.80042167268865 | 0.0049048326815486 |
| Watercress | Injury of muscle and tendon at lower leg level (finn-b-ST19_INJURY_MUSCLE_TENDON_LOWER_LEG_LEVEL) | All - Inverse variance weighted | 2.15834136805698 | 0.936734454585045 | 0.0212163410988597 |
| Watercress | Rheumatoid arthritis (ieu-a-834) | rs1447897 | 5.44461522367161 | 2.30468265911304 | 0.0181563398188729 |
| Watercress | Rheumatoid arthritis (ieu-a-834) | All - Inverse variance weighted | 4.08014665699615 | 1.79063254728214 | 0.022690477322947 |
| Watercress | Bone morphogenetic protein 6 (prot-a-255) | rs1447897 | -4.82026604005891 | 2.10836344323111 | 0.0222390792619651 |
| Watercress | Bone morphogenetic protein 6 (prot-a-255) | All - Inverse variance weighted | -1.29270908827629 | 0.644207536906157 | 0.0447852837427344 |
| Watercress | Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) | rs1447897 | -0.144855834614178 | 0.0561825746175574 | 0.0099286209720056 |
| Watercress | Non-cancer illness code self-reported: osteoarthritis (ukb-a-106) | All - Inverse variance weighted | -0.0537790308686054 | 0.0168459955126802 | 0.0014109942218735 |
| Watercress | Diagnoses - main ICD10: N32.0 Bladder-neck obstruction (ukb-b-123) | All - Inverse variance weighted | -0.0142320594727328 | 0.0066418742775853 | 0.032130960217226 |
| Watercress | Diagnoses - main ICD10: M25.5 Pain in joint (ukb-b-13019) | rs1447897 | -0.0204425953793042 | 0.0096966209854587 | 0.035012097067318 |
| Watercress | Diagnoses - main ICD10: M25.5 Pain in joint (ukb-b-13019) | All - Inverse variance weighted | -0.0172405181706177 | 0.0068111935990225 | 0.011367182513112 |
| Watercress | Non-cancer illness code, self-reported: fracture lower leg / ankle (ukb-b-13979) | All - Inverse variance weighted | 0.015458057273968 | 0.0063573267201833 | 0.0150350292688481 |
| Watercress | Non-cancer illness code, self-reported: osteoarthritis (ukb-b-14486) | All - Inverse variance weighted | -0.0385110771257574 | 0.0142802827305784 | 0.0070009147339256 |
| Watercress | Fracture resulting from simple fall (ukb-b-15251) | rs116023894 | -0.686354498756628 | 0.276448748731868 | 0.0130370738619312 |
| Watercress | Fracture resulting from simple fall (ukb-b-15251) | All - MR Egger | -0.878755996264188 | 0.302912225024604 | 0.0337503857453221 |
| Watercress | Fractured bone site(s): Arm (ukb-b-19255) | rs61917839 | 0.036515126690934 | 0.0172837492253225 | 0.0346276936064577 |
| Watercress | Fractured bone site(s): Arm (ukb-b-19255) | rs7704452 | -0.0463004151738244 | 0.0176822057717966 | 0.0088323742514308 |
| Watercress | Operative procedures - main OPCS: W26.2 Manipulation of fracture of bone NEC (ukb-b-1935) | rs1447897 | -0.0183648112531887 | 0.0083401868557219 | 0.0276676817484596 |
| Watercress | Diagnoses - secondary ICD10: Z96.6 Presence of orthopaedic joint implants (ukb-b-20477) | All - Inverse variance weighted | -0.0227069335446999 | 0.0095525658931734 | 0.0174516887255363 |
| Watercress | Fractured heel (right) (ukb-b-3499) | All - Inverse variance weighted | -0.0211137437987445 | 0.0099372578941334 | 0.0336112169657489 |
| Watercress | Operative procedures - main OPCS: W38.1 Primary total prosthetic replacement of hip joint not using cement (ukb-b-8136) | All - Inverse variance weighted | -0.0183500085095506 | 0.0075170824125853 | 0.014642283237406 |
| Watercress | Diagnoses - main ICD10: M13 Other arthritis (ukb-d-M13) | rs12141896 | -0.0274821897021758 | 0.0104733552800782 | 0.0086901216274684 |
| Watercress | Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) | rs12141896 | -0.0272682732369734 | 0.0098975425646828 | 0.0058682286212994 |
| Watercress | Ohter specific/unspecified arthritis (ukb-d-M13_ARTHRITISNAS) | All - MR Egger | -0.021725786685667 | 0.0088959356834482 | 0.0446137651680235 |
| Watercress | Other arthritis (FG) (ukb-d-RHEU_ARTHRITIS_OTH) | rs12141896 | -0.0274821897021758 | 0.0104733552800782 | 0.0086901216274684 |
| Watercress | Diagnoses - main ICD10: S42 Fracture of shoulder and upper arm (ukb-d-S42) | rs12141896 | -0.0312953937554653 | 0.0128583920580217 | 0.014939196604449 |
| Watercress | Diagnoses - main ICD10: S42 Fracture of shoulder and upper arm (ukb-d-S42) | All - Inverse variance weighted | -0.0099855821132947 | 0.0041805644456438 | 0.0169139614659953 |
| Watercress | Internal derangement of knee (ukb-e-835_CSA) | rs191852210 | 6.83433570256971 | 2.0554173257354 | 0.0008840725784864 |
| Watercress | Internal derangement of knee (ukb-e-835_CSA) | rs55718637 | -13.4767987309198 | 6.1982507079357 | 0.0296833121016406 |
| Watercress | Internal derangement of knee (ukb-e-835_CSA) | All - MR Egger | 6.93554433283862 | 2.78605454301912 | 0.0416344337511717 |