ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Pulses | Osteoprotegerin levels (ebi-a-GCST90000490) | All - Inverse variance weighted | 2.32746441344057 | 1.14628138652428 | 0.0423110514749642 |
| Pulses | Rheumatoid arthritis (ebi-a-GCST90013534) | rs1104785 | -1.37913355549859 | 0.676749551397078 | 0.0415620564509015 |
| Pulses | Rheumatoid arthritis (ebi-a-GCST90013534) | rs7115225 | 1.37447192451366 | 0.632425732138189 | 0.0297552384318807 |
| Pulses | Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016610) | rs7115225 | -1.05404288689698 | 0.375239267735326 | 0.0049697381034436 |
| Pulses | Crohn's disease vs rheumatoid arthritis (ordinary least squares (OLS)) (ebi-a-GCST90016610) | All - Inverse variance weighted | -0.558517027367611 | 0.202218916214853 | 0.0057458589356758 |
| Pulses | Neck circumference (ebi-a-GCST90017133) | rs6129441 | -3.46651823089908 | 1.71968267329197 | 0.043821994741791 |
| Pulses | Neck circumference (ebi-a-GCST90017133) | All - Inverse variance weighted | -1.92872133432021 | 0.697166278933025 | 0.0056658886973285 |
| Pulses | Neck circumference (BMI adjusted) (ebi-a-GCST90017136) | rs6845267 | -2.30780518389072 | 1.16501918724348 | 0.0476006910389957 |
| Pulses | Neck circumference (BMI adjusted) (ebi-a-GCST90017136) | All - Inverse variance weighted | -1.31672983751444 | 0.508892328366792 | 0.009669122217711 |
| Pulses | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | rs1104785 | 3.71186875160215 | 1.14842348115868 | 0.001228656148684 |
| Pulses | Ohter specific/unspecified arthritis (finn-b-M13_ARTHRITISNAS) | All - MR Egger | -14.5500174248903 | 4.35558020640173 | 0.0288211142058048 |
| Pulses | Chronic crepitant synovitis/bursitis of hand and wrist/periarhritis of wrist (finn-b-M13_CHRONSYNOVITISHANDWRIST) | All - Inverse variance weighted | -4.96378790204486 | 2.06768741871515 | 0.0163661092550955 |
| Pulses | Gluteal tendinitis (finn-b-M13_GLUTEALTEND) | rs1104785 | 10.6382978723404 | 3.93232504486029 | 0.0068233380061182 |
| Pulses | Gluteal tendinitis (finn-b-M13_GLUTEALTEND) | All - Inverse variance weighted | 3.6807982780386 | 1.60521291701716 | 0.0218463889182742 |
| Pulses | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | rs7115225 | 6.52241738411853 | 3.00613031343019 | 0.0300291654222119 |
| Pulses | Polyarthritis, unspecified (finn-b-M13_POLYARTHRITIS) | All - Inverse variance weighted | 2.66850177646351 | 1.30249331913742 | 0.0404851709980807 |
| Pulses | Spinal osteochondrosis (finn-b-M13_SPINALOSTEOCHON) | rs139435676 | 10.0427053041013 | 5.11657888761107 | 0.0496720472553645 |
| Pulses | Spinal osteochondrosis (finn-b-M13_SPINALOSTEOCHON) | All - Inverse variance weighted | 5.52702950671016 | 2.24020288844879 | 0.0136174115317401 |
| Pulses | Spondylosis (finn-b-M13_SPONDYLOSIS) | rs7115225 | 1.93943891189045 | 0.767343221661003 | 0.01148868119623 |
| Pulses | Spondylosis (finn-b-M13_SPONDYLOSIS) | All - Inverse variance weighted | 1.22360722622969 | 0.332252955793204 | 0.000230724179239 |
| Pulses | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | rs1104785 | 2.69161753396565 | 1.05101256088183 | 0.0104378683789466 |
| Pulses | Other arthritis (FG) (finn-b-RHEU_ARTHRITIS_OTH) | All - MR Egger | -12.1195042602598 | 3.98721881022186 | 0.0384177162176367 |
| Pulses | Injury of muscle and tendon at forearm level (finn-b-ST19_INJURY_MUSCLE_TENDON_FOREA_LEVEL) | All - Inverse variance weighted | 3.71147193933837 | 1.80421705531392 | 0.0396756997097962 |
| Pulses | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | rs12150952 | -7.01261715790685 | 3.43094674298044 | 0.0409604001169518 |
| Pulses | Other and unspecified injuries of ankle and foot (finn-b-ST19_OTHER_UNSPE_INJURI_ANKLE_FOOT) | All - Inverse variance weighted | -3.08687080022983 | 1.32942821618114 | 0.0202354274091054 |
| Pulses | Operative procedures - main OPCS: S06.5 Excision of lesion of skin of head or neck NEC (ukb-b-10810) | rs1104785 | -0.0332426044603948 | 0.0158690079466803 | 0.0361876172534075 |
| Pulses | Diagnoses - secondary ICD10: G55.1 Nerve root and plexus compressions in intervertebral disk disorders (ukb-b-1220) | All - Inverse variance weighted | -0.0067203301552094 | 0.0029820101322948 | 0.0242198205071675 |
| Pulses | Ankle spacing width (left) (ukb-b-2122) | rs139435676 | 0.663111553872411 | 0.143037130906774 | 3.55319064146127e-06 |
| Pulses | Ankle spacing width (left) (ukb-b-2122) | rs6129441 | 0.435961279986967 | 0.164531092315281 | 0.0080558570748975 |
| Pulses | Ankle spacing width (left) (ukb-b-2122) | All - Inverse variance weighted | 0.267189969046278 | 0.107405664361539 | 0.012858257951967 |
| Pulses | Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC (ukb-b-5602) | rs7115225 | 0.0201582750798965 | 0.0079632940105067 | 0.0113608507411902 |
| Pulses | Operative procedures - main OPCS: W36.5 Diagnostic extraction of bone marrow NEC (ukb-b-5602) | All - Inverse variance weighted | 0.008035359952219 | 0.0030615558153994 | 0.0086750767646276 |
| Pulses | Ankle spacing width (right) (ukb-b-8607) | rs139435676 | 0.608023176600716 | 0.144775742215255 | 2.6719963524055e-05 |
| Pulses | Ankle spacing width (right) (ukb-b-8607) | rs6129441 | 0.488674984500229 | 0.166554887292903 | 0.0033460514489017 |
| Pulses | Ankle spacing width (right) (ukb-b-8607) | All - Inverse variance weighted | 0.287245134143997 | 0.103408112461581 | 0.0054731421173159 |
| Pulses | Pain in joint (ukb-e-745_AFR) | rs1104785 | -11.7046911048449 | 5.40374263009485 | 0.0303085770171313 |
| Pulses | Pain in joint (ukb-e-745_AFR) | All - Inverse variance weighted | -7.04387496289258 | 2.5723738321827 | 0.006176182183081 |