ONMR: An Orthopedic and Nutritional Mendelian Randomization Database
| Intake (exposure) | Outcome | SNP | b | se | P-value |
|---|---|---|---|---|---|
| Fresh tomato | Osteoarthritis of the hip or knee (ebi-a-GCST007092) | All - Inverse variance weighted | 0.121963415063542 | 0.0616236573580647 | 0.0477973787023084 |
| Fresh tomato | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs114826856 | 7.60744053242636 | 3.07677772879007 | 0.0134158587030887 |
| Fresh tomato | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | rs12607299 | 5.18472788962 | 2.64506447030953 | 0.0499780499546084 |
| Fresh tomato | Benign neoplasm: Short bones of upper limb (finn-b-CD2_BENIGN_BONE_SHORT_UPPER) | All - Inverse variance weighted | 1.89389994720384 | 0.859569544895296 | 0.0275727613352627 |
| Fresh tomato | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs114826856 | 7.75860259074972 | 3.11036929730638 | 0.0126159138568568 |
| Fresh tomato | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | rs12607299 | 5.20229473145318 | 2.64757401914284 | 0.049422466124017 |
| Fresh tomato | Benign neoplasm: Short bones of upper limb (all cancers excluded) (finn-b-CD2_BENIGN_BONE_SHORT_UPPER_EXALLC) | All - Inverse variance weighted | 1.90552202644186 | 0.868438146886953 | 0.0282214446236512 |
| Fresh tomato | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | rs2367001 | -2.76580167575043 | 1.2202066216546 | 0.0234105961611167 |
| Fresh tomato | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | rs9953073 | -2.43104897241959 | 1.01917640767056 | 0.0170648578386862 |
| Fresh tomato | Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck (finn-b-CD2_BENIGN_LIPO_SKIN_HEADFACENECK) | All - MR Egger | -3.77417090960003 | 1.39399061582364 | 0.0267632073423442 |
| Fresh tomato | Pain in joint (finn-b-JOINTPAIN) | All - Inverse variance weighted | 0.230696983951171 | 0.115313210549867 | 0.0454342276466538 |
| Fresh tomato | Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) | rs76800056 | 8.21186117352099 | 4.12773198810612 | 0.0466530310341851 |
| Fresh tomato | Ankylosis of joint (finn-b-M13_ANKYLOSISJOINT) | All - Inverse variance weighted | 3.03023898154553 | 1.26551140089799 | 0.0166440500405374 |
| Fresh tomato | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs76800056 | 9.66771030782368 | 3.05098499942469 | 0.0015311300968768 |
| Fresh tomato | Other bursitis of knee (finn-b-M13_BURSITISKNEEOTH) | rs7718343 | -5.7886504734824 | 2.8767614617498 | 0.0441977208337911 |
| Fresh tomato | Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) | rs76800056 | -3.62266619026567 | 1.6084589437221 | 0.0243059072176769 |
| Fresh tomato | Panniculitis affecting regions of neck and back (finn-b-M13_PANNICULITIS) | All - Inverse variance weighted | -1.12703377184126 | 0.488691889216572 | 0.0210980268311828 |
| Fresh tomato | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | rs114826856 | 2.04646133820411 | 1.0376645461989 | 0.0485890538809074 |
| Fresh tomato | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | rs117498265 | 3.84068439232396 | 1.14830926839371 | 0.0008238858740071 |
| Fresh tomato | Trochanteric bursitis (finn-b-M13_TROCHANTERICBURSITIS) | All - MR Egger | 2.91429826047497 | 1.18010909853144 | 0.038739674450575 |
| Fresh tomato | Villonodular synovitis (pigmented) (finn-b-M13_VILLONODULAR) | All - MR Egger | 9.2787352399146 | 3.50169169390791 | 0.0292654962509573 |
| Fresh tomato | Pain (limb, back, neck, head abdominally) (finn-b-PAIN) | rs2281147 | 0.330799766132258 | 0.1577068652491 | 0.0359439454460275 |
| Fresh tomato | Pain (limb, back, neck, head abdominally) (finn-b-PAIN) | All - Inverse variance weighted | 0.153160972197475 | 0.0584027398492683 | 0.0087288202297104 |
| Fresh tomato | Crushing injury of wrist and hand (finn-b-ST19_CRUSHI_INJURY_WRIST_HAND) | rs11781542 | -8.16863763358402 | 3.19076896859458 | 0.0104646766800206 |
| Fresh tomato | Crushing injury of wrist and hand (finn-b-ST19_CRUSHI_INJURY_WRIST_HAND) | All - Inverse variance weighted | -2.9106143092667 | 0.878184914720834 | 0.0009185564994491 |
| Fresh tomato | Dislocation, sprain and strain of joints and ligaments of thorax (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_THORAX) | rs76800056 | 5.19357827611475 | 2.15712754425382 | 0.01605617369096 |
| Fresh tomato | Dislocation, sprain and strain of joints and ligaments of thorax (finn-b-ST19_DISLO_SPRAIN_STRAIN_JOINTS_LIGAM_THORAX) | All - Inverse variance weighted | 1.57349202112395 | 0.653296854669148 | 0.0160164431931938 |
| Fresh tomato | Traumatic amputation of wrist and hand (finn-b-ST19_TRAUMAT_AMPUT_WRIST_HAND) | rs76800056 | -3.39375147613655 | 1.61693726646763 | 0.0358277973465449 |
| Fresh tomato | Traumatic amputation of wrist and hand (finn-b-ST19_TRAUMAT_AMPUT_WRIST_HAND) | All - Inverse variance weighted | -1.01713711347521 | 0.488474717257906 | 0.0373176530644788 |
| Fresh tomato | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | rs7718343 | 0.0065364605480637 | 0.0031040182219543 | 0.0352211975866083 |
| Fresh tomato | Diagnoses - main ICD10: M24 Other specific joint derangements (ukb-a-567) | All - Inverse variance weighted | 0.0030564111002573 | 0.0009846106325345 | 0.0019080559223295 |
| Fresh tomato | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | rs114826856 | 0.0030609424534441 | 0.0013811435829606 | 0.026675228401633 |
| Fresh tomato | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | rs117498265 | 0.0023915180956111 | 0.0012168489778509 | 0.049375267166266 |
| Fresh tomato | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | rs9953073 | 0.0026295668118267 | 0.0012714111085644 | 0.0386186803420091 |
| Fresh tomato | Diagnoses - main ICD10: S76 Injury of muscle and tendon at hip and thigh level (ukb-a-592) | All - Inverse variance weighted | 0.0011824972732588 | 0.0004946434609577 | 0.0168206254823643 |
| Fresh tomato | Non-cancer illness code self-reported: ankylosing spondylitis (ukb-a-88) | All - Inverse variance weighted | -0.002797844136019 | 0.0010579444046398 | 0.0081786539190159 |
| Fresh tomato | Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) | rs9953073 | 0.0144353579341432 | 0.0060516158606463 | 0.0170618364134469 |
| Fresh tomato | Operative procedures - secondary OPCS: Z84.6 Knee joint (ukb-b-10001) | All - Inverse variance weighted | 0.0047057907489844 | 0.0023130136438316 | 0.0419027549169987 |
| Fresh tomato | Operative procedures - main OPCS: S06.5 Excision of lesion of skin of head or neck NEC (ukb-b-10810) | All - Inverse variance weighted | 0.0057306218096173 | 0.0025002058361968 | 0.0219021806794838 |
| Fresh tomato | Fracture resulting from simple fall (ukb-b-15251) | rs11785751 | 0.247329736701052 | 0.086495788982969 | 0.0042438632174619 |
| Fresh tomato | Fracture resulting from simple fall (ukb-b-15251) | All - MR Egger | -0.304695506817921 | 0.128901624046721 | 0.0456876141873255 |
| Fresh tomato | Heel bone ultrasound T-score, manual entry (ukb-b-17612) | All - Inverse variance weighted | 0.108816185790363 | 0.0533618011736629 | 0.0414285737323997 |
| Fresh tomato | Non-cancer illness code, self-reported: joint disorder (ukb-b-8201) | rs11781542 | -0.0073402933803315 | 0.0037030185616201 | 0.0474517251700064 |
| Fresh tomato | Non-cancer illness code, self-reported: joint disorder (ukb-b-8201) | All - Inverse variance weighted | -0.0043567447729096 | 0.0018884520013734 | 0.021052281316255 |
| Fresh tomato | Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure (ukb-b-8566) | rs12607299 | 0.0086111905801575 | 0.0036440154788972 | 0.0181225424825159 |
| Fresh tomato | Operative procedures - main OPCS: W84.8 Other specified therapeutic endoscopic operations on other joint structure (ukb-b-8566) | All - Inverse variance weighted | 0.0042916646969701 | 0.002170295427616 | 0.047990058273101 |
| Fresh tomato | Cervicalgia (ukb-d-M13_CERVICALGIA) | All - Inverse variance weighted | 0.0021473560349907 | 0.0010803800192471 | 0.0468566933143897 |
| Fresh tomato | Diagnoses - main ICD10: M47 Spondylosis (ukb-d-M47) | rs114826856 | -0.0142147445991056 | 0.0048960918309504 | 0.0036927171634334 |
| Fresh tomato | Diagnoses - main ICD10: M47 Spondylosis (ukb-d-M47) | rs117498265 | -0.0117091660711521 | 0.0043074208461193 | 0.0065604316697041 |
| Fresh tomato | Diagnoses - main ICD10: M47 Spondylosis (ukb-d-M47) | rs76800056 | -0.0101222453021008 | 0.0048639289758791 | 0.0374262080481696 |
| Fresh tomato | Diagnoses - main ICD10: M47 Spondylosis (ukb-d-M47) | All - MR Egger | -0.0191829747254694 | 0.0045847869078894 | 0.0030625942725254 |
| Fresh tomato | Fractured/broken bones in last 5 years (ukb-e-2463_AFR) | All - Inverse variance weighted | 1.55836202822306 | 0.71975991209577 | 0.0303789809952604 |
| Fresh tomato | Ankle spacing width (right) (ukb-e-4119_AFR) | All - Inverse variance weighted | -0.447523529427627 | 0.221110043480762 | 0.0429716401981674 |
| Fresh tomato | Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) | rs12607299 | 1.03669462304067 | 0.509438413162082 | 0.0418533513686107 |
| Fresh tomato | Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) | rs7718343 | 1.18028567942228 | 0.579974338400328 | 0.0418442979927488 |
| Fresh tomato | Heel bone mineral density (BMD) (right) (ukb-e-4124_CSA) | All - Inverse variance weighted | 0.527225393701295 | 0.186529966504372 | 0.0047060970276075 |
| Fresh tomato | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA) | rs12607299 | 1.12653647127319 | 0.511697007112061 | 0.0276957396522912 |
| Fresh tomato | Heel bone mineral density (BMD) T-score, automated (right) (ukb-e-4125_CSA) | All - Inverse variance weighted | 0.535513888716575 | 0.18744266238465 | 0.0042773627103947 |